WO2000012049A3 - A method for the treatment of staphylococcal disease - Google Patents
A method for the treatment of staphylococcal disease Download PDFInfo
- Publication number
- WO2000012049A3 WO2000012049A3 PCT/US1999/020396 US9920396W WO0012049A3 WO 2000012049 A3 WO2000012049 A3 WO 2000012049A3 US 9920396 W US9920396 W US 9920396W WO 0012049 A3 WO0012049 A3 WO 0012049A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- treatment
- lysostaphin
- staphylococcal
- staphylococcal disease
- effective
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24075—Lysostaphin (3.4.24.75)
Abstract
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU58111/99A AU5811199A (en) | 1998-08-27 | 1999-08-27 | A method for the treatment of staphylococcal disease |
DE69943089T DE69943089D1 (en) | 1998-08-27 | 1999-08-27 | METHOD FOR THE TREATMENT OF STAPHYLOKOCKSINFECTIONS |
IL14164899A IL141648A0 (en) | 1998-08-27 | 1999-08-27 | A method for the treatment of staphylococcal disease |
AT99945525T ATE493145T1 (en) | 1998-08-27 | 1999-08-27 | METHOD OF TREATING STAPHYLOCOCCAL INFECTIONS |
EP99945525A EP1107722B1 (en) | 1998-08-27 | 1999-08-27 | A method for the treatment of staphylococcal infection |
JP2000567170A JP2002523437A (en) | 1998-08-27 | 1999-08-27 | Methods for treating staphylococcal diseases |
CA002341699A CA2341699A1 (en) | 1998-08-27 | 1999-08-27 | A method for the treatment of staphylococcal disease |
NO20010953A NO20010953L (en) | 1998-08-27 | 2001-02-26 | A method for the treatment of staphylococcal disease |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/140,732 US6028051A (en) | 1997-07-23 | 1998-08-27 | Method for the treatment of staphylococcal disease |
US09/140,732 | 1998-08-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000012049A2 WO2000012049A2 (en) | 2000-03-09 |
WO2000012049A3 true WO2000012049A3 (en) | 2000-05-25 |
Family
ID=22492556
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/020396 WO2000012049A2 (en) | 1998-08-27 | 1999-08-27 | A method for the treatment of staphylococcal disease |
Country Status (12)
Country | Link |
---|---|
US (1) | US6028051A (en) |
EP (1) | EP1107722B1 (en) |
JP (1) | JP2002523437A (en) |
AR (1) | AR023645A1 (en) |
AT (1) | ATE493145T1 (en) |
AU (1) | AU5811199A (en) |
CA (1) | CA2341699A1 (en) |
DE (1) | DE69943089D1 (en) |
IL (1) | IL141648A0 (en) |
NO (1) | NO20010953L (en) |
WO (1) | WO2000012049A2 (en) |
ZA (1) | ZA995444B (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6875903B2 (en) * | 1998-06-22 | 2005-04-05 | University Of Vermont | Treatment of Staphylococcus infections |
US7091332B1 (en) | 1998-06-22 | 2006-08-15 | University Of Vermont | Treatment of staphylococcus infections |
US6569830B1 (en) | 1999-03-05 | 2003-05-27 | Ambi, Inc. | Compositions and methods for treatment of staphylococcal infection while suppressing formation of antibiotic-resistant strains |
US20030211995A1 (en) * | 2001-12-21 | 2003-11-13 | Kokai-Kun John Fitzgerald | Methods and formulations for eradicating or alleviating staphylococcal nasal colonization using lysostaphin |
JP4348194B2 (en) * | 2001-12-21 | 2009-10-21 | バイオシネクサス インコーポレーテッド | A truncated lysostaphin molecule with enhanced staphylococcal lytic activity |
US6759881B2 (en) * | 2002-03-22 | 2004-07-06 | Rambus Inc. | System with phase jumping locked loop circuit |
BR0308710A (en) * | 2002-03-26 | 2007-01-09 | Biosynexus Inc | antimicrobial polymer conjugates |
BR0308285A (en) * | 2002-03-26 | 2005-04-12 | Biosynexus Inc | Bacterial biofilm disruption by enzymes |
JP2006514944A (en) * | 2002-12-10 | 2006-05-18 | バイオシネクサス インコーポレーテッド | Anti-infective preparation for topical use |
US20100221237A1 (en) * | 2003-03-26 | 2010-09-02 | Biosynexus Incorporated | Enzyme disruption of bacterial biofilms |
WO2007041621A2 (en) * | 2005-10-03 | 2007-04-12 | Xingsheng Sean Ling | Hybridization assisted nanopore sequencing |
WO2008105826A2 (en) * | 2006-09-05 | 2008-09-04 | Biosynexus Incorporated | Compositions compromising lysostaphin variants and methods of using the same |
US20110044968A1 (en) * | 2008-03-10 | 2011-02-24 | Pharmal N Corporation | Compositions for treatment with metallopeptidases, methods of making and using the same |
WO2009150171A1 (en) * | 2008-06-10 | 2009-12-17 | Profos Ag | Method of treatment of inflammatory diseases |
CN106795506B (en) * | 2014-05-14 | 2020-11-27 | 达特茅斯学院理事会 | Deimmunized lysostaphin and methods of use |
EP3485899A4 (en) | 2017-09-25 | 2020-05-20 | Georgy Georgievich Chumburidze | Thermostable composition with antiviral and antibacterial activity and use thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3067099A (en) * | 1955-09-16 | 1962-12-04 | Lilly Co Eli | Vancomycin and method for its preparation |
US4980163A (en) * | 1989-03-01 | 1990-12-25 | Public Health Research Institute Of The City Of New York | Novel bacteriocin compositions for use as enhanced broad range bactericides and methods of preventing and treating microbial infection |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4931390A (en) * | 1986-04-16 | 1990-06-05 | Public Health Research Institute Of The City Of New York, Inc. | Expression of the cloned lysostaphin gene |
US5858962A (en) * | 1987-05-11 | 1999-01-12 | Ambi Inc. | Composition for treating mastitis and other staphylococcal infections |
US5342612A (en) * | 1991-12-20 | 1994-08-30 | American Cyanamid Company | Compositions for the treatment of mammalian diseases |
-
1998
- 1998-08-27 US US09/140,732 patent/US6028051A/en not_active Expired - Lifetime
-
1999
- 1999-08-25 ZA ZA9905444A patent/ZA995444B/en unknown
- 1999-08-26 AR ARP990104279A patent/AR023645A1/en unknown
- 1999-08-27 WO PCT/US1999/020396 patent/WO2000012049A2/en active Application Filing
- 1999-08-27 DE DE69943089T patent/DE69943089D1/en not_active Expired - Lifetime
- 1999-08-27 JP JP2000567170A patent/JP2002523437A/en active Pending
- 1999-08-27 CA CA002341699A patent/CA2341699A1/en not_active Abandoned
- 1999-08-27 EP EP99945525A patent/EP1107722B1/en not_active Expired - Lifetime
- 1999-08-27 AU AU58111/99A patent/AU5811199A/en not_active Abandoned
- 1999-08-27 AT AT99945525T patent/ATE493145T1/en not_active IP Right Cessation
- 1999-08-27 IL IL14164899A patent/IL141648A0/en unknown
-
2001
- 2001-02-26 NO NO20010953A patent/NO20010953L/en not_active Application Discontinuation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3067099A (en) * | 1955-09-16 | 1962-12-04 | Lilly Co Eli | Vancomycin and method for its preparation |
US4980163A (en) * | 1989-03-01 | 1990-12-25 | Public Health Research Institute Of The City Of New York | Novel bacteriocin compositions for use as enhanced broad range bactericides and methods of preventing and treating microbial infection |
Also Published As
Publication number | Publication date |
---|---|
EP1107722A4 (en) | 2006-05-17 |
US6028051A (en) | 2000-02-22 |
NO20010953D0 (en) | 2001-02-26 |
NO20010953L (en) | 2001-03-21 |
DE69943089D1 (en) | 2011-02-10 |
IL141648A0 (en) | 2002-03-10 |
WO2000012049A2 (en) | 2000-03-09 |
ATE493145T1 (en) | 2011-01-15 |
AU5811199A (en) | 2000-03-21 |
AR023645A1 (en) | 2002-09-04 |
CA2341699A1 (en) | 2000-03-09 |
ZA995444B (en) | 2000-07-10 |
JP2002523437A (en) | 2002-07-30 |
EP1107722A2 (en) | 2001-06-20 |
EP1107722B1 (en) | 2010-12-29 |
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