WO2000022413A8 - Methods and apparatus for tailoring spectroscopic calibration models - Google Patents

Methods and apparatus for tailoring spectroscopic calibration models

Info

Publication number
WO2000022413A8
WO2000022413A8 PCT/US1999/023665 US9923665W WO0022413A8 WO 2000022413 A8 WO2000022413 A8 WO 2000022413A8 US 9923665 W US9923665 W US 9923665W WO 0022413 A8 WO0022413 A8 WO 0022413A8
Authority
WO
WIPO (PCT)
Prior art keywords
subject
calibration
tailored
methods
phase
Prior art date
Application number
PCT/US1999/023665
Other languages
French (fr)
Other versions
WO2000022413A1 (en
Inventor
Edward V Thomas
Robert K Rowe
Original Assignee
Rio Grande Medical Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rio Grande Medical Tech Inc filed Critical Rio Grande Medical Tech Inc
Priority to JP2000576263A priority Critical patent/JP4672147B2/en
Priority to EP99951924A priority patent/EP1129333A4/en
Priority to MXPA01003804A priority patent/MXPA01003804A/en
Priority to AU64258/99A priority patent/AU761015B2/en
Priority to CA002347494A priority patent/CA2347494A1/en
Priority to KR1020017004713A priority patent/KR20010090791A/en
Publication of WO2000022413A1 publication Critical patent/WO2000022413A1/en
Priority to NO20011885A priority patent/NO20011885L/en
Priority to HK02101171.7A priority patent/HK1040111A1/en
Publication of WO2000022413A8 publication Critical patent/WO2000022413A8/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1495Calibrating or testing of in-vivo probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/359Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light

Abstract

A method and apparatus for non-invasively measuring a biological attribute, such as the concentration of an analyte, particularly a blood analyte in tissue such as glucose. The method utilizes spectrographic techniques in conjunction with an improved subject tailored calibration model. In a calibration phase, calibration model data is modified to reduce or eliminate subject-specific attributes, resulting in a calibration data set modeling within subject physiological variation, sample location, insertion variations, and instrument variation. In a prediction phase, the prediction process is tailored for each target subject separately using a minimal number of spectral measurements from each subject.
PCT/US1999/023665 1998-10-13 1999-10-12 Methods and apparatus for tailoring spectroscopic calibration models WO2000022413A1 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP2000576263A JP4672147B2 (en) 1998-10-13 1999-10-12 Method for creating a spectroscopic calibration model
EP99951924A EP1129333A4 (en) 1998-10-13 1999-10-12 Methods and apparatus for tailoring spectroscopic calibration models
MXPA01003804A MXPA01003804A (en) 1998-10-13 1999-10-12 Methods and apparatus for tailoring spectroscopic calibration models.
AU64258/99A AU761015B2 (en) 1998-10-13 1999-10-12 Methods and apparatus for tailoring spectroscopic calibration models
CA002347494A CA2347494A1 (en) 1998-10-13 1999-10-12 Methods and apparatus for tailoring spectroscopic calibration models
KR1020017004713A KR20010090791A (en) 1998-10-13 1999-10-12 Methods and apparatus for tailoring spectorscopic calibration models
NO20011885A NO20011885L (en) 1998-10-13 2001-04-11 Method and apparatus for adapting spectroscopic calibration models
HK02101171.7A HK1040111A1 (en) 1998-10-13 2002-02-18 Methods and apparatus for tailoring spectroscopic calibration models

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US17002298A 1998-10-13 1998-10-13
US09/170,022 1998-10-13
US09/415,432 1999-10-08
US09/415,432 US6157041A (en) 1998-10-13 1999-10-08 Methods and apparatus for tailoring spectroscopic calibration models

Publications (2)

Publication Number Publication Date
WO2000022413A1 WO2000022413A1 (en) 2000-04-20
WO2000022413A8 true WO2000022413A8 (en) 2002-06-06

Family

ID=22618213

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/023665 WO2000022413A1 (en) 1998-10-13 1999-10-12 Methods and apparatus for tailoring spectroscopic calibration models

Country Status (11)

Country Link
US (2) US6157041A (en)
EP (1) EP1129333A4 (en)
JP (1) JP4672147B2 (en)
KR (1) KR20010090791A (en)
CN (1) CN100387969C (en)
AU (1) AU761015B2 (en)
CA (1) CA2347494A1 (en)
HK (1) HK1040111A1 (en)
MX (1) MXPA01003804A (en)
NO (1) NO20011885L (en)
WO (1) WO2000022413A1 (en)

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