WO2000024453A2 - Axially activated hemostasis valve with lumen size selection - Google Patents
Axially activated hemostasis valve with lumen size selection Download PDFInfo
- Publication number
- WO2000024453A2 WO2000024453A2 PCT/US1999/025010 US9925010W WO0024453A2 WO 2000024453 A2 WO2000024453 A2 WO 2000024453A2 US 9925010 W US9925010 W US 9925010W WO 0024453 A2 WO0024453 A2 WO 0024453A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hemostasis valve
- lumen
- valve
- cylinder
- hemostasis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/02—Access sites
- A61M39/06—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
- A61M39/0613—Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof with means for adjusting the seal opening or pressure
Definitions
- the present invention generally relates to the field of minimally invasive medicine. More particularly, the present invention relates to those devices, commonly known as y- adapters, which are used to prevent blood from exiting a patient during a minimally invasive procedure. Such procedures include but are not limited to angioplasty, atherectomy, stenting, angiography, venous filtration, liquid infusion, dialysis, and intravascular ultrasound. Those skilled in the art will recognize the benefits of applying the present invention to similar fields not discussed herein. Background of the Invention
- Angioplasty has gained wide acceptance in recent years as an efficient and effective method for treating various types of vascular diseases.
- angioplasty is widely used for opening stenoses in the coronary arteries, although it is also used for treatment of stenoses in other parts of the vascular system.
- the most widely used form of angioplasty makes use of a guide catheter positioned within the vascular system of a patient. The distal end of the guide catheter is inserted into an introducer sheath which is then inserted into the femoral artery located in the groin of the patient and pushed distally up through the vascular system until the distal end of the guide catheter is located in the ostium of the coronary artery.
- the distal end of the guide catheter is normally curved so that the distal tip of the guide catheter is more easily directed to the coronary ostium of the patient.
- a Y-adapter assembly is releasably secured to the proximal end of the guide catheter.
- the proximal end of the guide catheter and the Y-adapter protrude outside the patient's body.
- the Y-adapter provides an entry way for subsequent insertion of additional angioplasty devices into the patient's vascular system through the guide catheter.
- Prior art Y-adapters typically includes a main body portion that is secured at its distal end to the guide catheter via a luer fitting.
- the Y-adapter further includes a side branch that defines an infusion port.
- the main body portion of the Y-adapter is configured to receive a dilatation balloon catheter.
- the proximal end of the side branch and the main body portion typically include valves which are known as Tuohy-Borst valves.
- Tuohy-Borst valves are seals that minimize back-bleeding during the minimally invasive procedure.
- Each Tuohy-Borst seal includes a gasket having a through lumen and a threadably attached cap.
- the through lumen is configured to receive a shaft of a dilatation catheter or other minimally invasive device.
- the cap can be rotatably tightened to compress the gasket and thereby decrease the diameter of the through lumen to form a fluid tight seal about the shaft of the dilatation catheter.
- the cap of the Tuohy-Borst seal is tightened too much, the dilatation catheter may be damaged or the flow of inflation fluid through the catheter may be restricted so as to make inflation of the balloon of the dilatation catheter difficult.
- tightening the cap too little may allow back-bleeding through the proximal ends of the side branch and the main body portion of the Y-adapter.
- a Y-adapter of efficient design which incorporates a valve member that provides an effective releasable seal about the shaft of a dilatation catheter and provides simplified physician use.
- the valve member would preferably provide a fluid tight seal about the dilatation catheter to prevent back-bleeding, while minimizing damage to the catheter.
- the seal formed by the vale member would not restrict the flow of inflation fluid through the dilatation catheter. It would also be advantageous to provide a valve member which may selectively seal about certain diameter devices while at the same time providing visual feedback as to diameter.
- Figure 1 depicts a y-adapter assembly which incorporates the present invention.
- Figure 2 is an exploded view of the assembly shown in Figure 1.
- Figure 3 is an enlarged side view of the cam depicted in Figure 2.
- Figure 4A is a partial side view the assembly of Figure 1 , where the valve is in the fully open position.
- Figure 4B is an enlarged partial side view the assembly of Figure 4A.
- Figure 4C is a partial side view the assembly of Figure 4B where the valve is partially closed.
- Figure 4D is a partial side view the assembly of Figure 4B where the valve is completely closed.
- Figure 5 is a depiction of an alternative y-adapter assembly which incorporates the present invention.
- Figure 6 is a depiction of another alternative y-adapter assembly which incorporates the present invention.
- Figure 7A is a side view of a valve.
- Figure 7B is an end view of the valve of Figure 7A.
- Figure 7C is a side view of an alternative valve.
- Figure 7D is an end view of the valve of Figure 7C.
- Figure 8 depicts an axially activated Y-adapter assembly.
- Figure 9 is an exploded view of the assembly shown in Figure 8.
- Figure 10 is a partial sectioned side view of Figure 8.
- Figure 1 depicts an embodiment of a y-adapter 50 with actuating button 51.
- Actuating button 51 may be moved either proximally or distally with the thumb or forefinger and thereby actuate the opening or closing of y-adapter 50.
- Figure 2 is an exploded view of y-adapter 50.
- Actuating button 51 is designed to slide within 62 of distal housing 70. Movement of button 51 actuates motion of cam 20.
- Cam 20 is pinned to proximal housing 80 by pin 22. Accordingly pin 22 defines the axis of rotation of cam 20.
- Follower surface 30 is integrally molded with cylinder 40 and serves to compress valve 53 when cylinder 40 is moved axially. Washers 60 may additionally be provided proximally and distally of valve 53.
- Proximal housing 80 is bonded to body 90 and when brought into contact with distal housing 20, encases cylinder 40, cam 20, valve 53 and washers 60.
- Valve 53 may preferably be formed of medical grade silicone such as Wacker R4000. The amount of force needed to compress valve 53 is dependent on the relative hardness of the material used for valve 53. Accordingly, it may be desirable to provide a material for valve 53 that is 20-50 Shore A durometer. Preferably, the durometer of the material of valve 53 may be 30 Shore A.
- Lower durometer valves or valves with a cutout as shown in Figure 7A-D are examples of valves which require less compression to close valve lumen 62. Cylindrical valves with cutouts provide reduced friction and thereby allow physicians to have better tactile feedback during a procedure.
- Proximal housing 80, distal housing 70, cylinder 40 and body 90 may be formed of a suitable medical grade polymer.
- proximal housing 80, distal housing 70, cylinder 40 and body 90 may be formed of polycarbonate.
- Button 51 may be formed of a medical grade acetal-copolymer such as Celcon, natural.
- Detents 120 may be formed in proximal housing 70. Detents 120 may be spaced at regular positions along the travel length of button 51 and require button 51 to click into positions which correspond with particular diameters of valve lumen 62. Detents 120 may be conveniently positioned to correspond to atherectomy devices, stent catheters, balloon catheters and guide wire (8 Fr., 5 Fr., 3 Fr. and .014 inches respectively). Button 53 may also be moved rapidly such that the valve lumen 62 moves from completely open to completely closed. In an alternative embodiment, button 51 may be designed such that specified positions along it travel length are indexed by radial teeth (not shown) which project from button 51 and mate with slots in proximal housing 70. In yet another embodiment of button 51, button 51 may have a spring mechanism which may include a coil spring or a leaf spring which maintains the button position but may also be depressed and allow the diameter of valve lumen 62 to be fine tuned.
- Figure 3 depicts cam 20 with button contact surface 29 and follower contact surface 25.
- Mechanical advantage is gained by the moment arm 27 or the perpendicular distance from the point which the button 51 contacts button contact surface 29, with varying force F, to the cam axis 23.
- Moment arm 27 is a key factor in the amount of force required to actuate button 51 and compress valve 53.
- the location of cam axis 23 and its position relative to the follower contact surface 25 also is a factor in the mechanical advantage provide by cam 20.
- the ratio of the distance the button travels axially compared to the axial travel of the follower may be a factor of 3: 1 or more depending on the size and design of the cam 20.
- the cam 20 should be as small as possible.
- small cam sizes have fairly high stress and therefore require stronger materials of construction.
- filled materials may be required to withstand the high stress. Suitable filled materials may include glass filled ABS or CelconTM.
- valve 53 will be sized such that any device may be used.
- a total range for valve 53 may be 9.6-0 French or .125-0 inches.
- Ergonomic designs of button 51 may include various shapes or sizes as well as being fully circumferential. These designs allow easy access irrespective of the position of the y-adapter.
- Figures 5 and 6 are examples of alternative button designs 51.
- a cylindrical activation surface which encompasses the total circumference of the valve may also be used and will allow for easy access from any angle.
- Axial adjustment may also include another mechanism which allows the user analog adjustment.
- Analog adjustment provides for fine tuning of the valve to the required amount of hemostasis and the appropriate feel or lumen size for the particular device within the y-adapter.
- One such method of achieving analog adjustment is through the addition of a cylindrical threaded surface which can be adjusted for fine tuning.
- FIG. 8 depicts this embodiment of a y-adapter 160 with a cylindrical actuating button, hereafter called a collar 161.
- the cylindrical actuating collar 161 may be moved either proximally or distally with the thumb or forefingers and thereby actuate the opening or closing of the y-adapter.
- Figure 9 is an exploded view of the assembly shown in Figure 8.
- Various lumen sizes would be achieved by axially sliding the collar 161 along the adjusting threads 162 to snap fit into certain positions.
- the partial sectioned side view in Figure 10 shows how the snap fit would be achieved by axially located spring arms 164 located within the adjusting threads 162.
- the spring arms deflect when forced to move axially and snap into the thread minor diameter in either direction to achieve closing or opening of the y-adapter lumen.
- the collar 161 may be rotated to achieve fine tuning of the y-adapter lumen.
- a spring mechanism 163 would increase the ratio of manual motion to valve compression, thereby providing the physician with greater tactile feedback.
- the spring 163 actuates the cylindrical push rod 40 similar to that found in the embodiment of Figure 2.
- the pushrod 40 then compresses valve 53 to reduce the lumen size.
- a secondary mechanism may be adjusted for fine tuning at each interval.
Abstract
Description
Claims
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99970933A EP1042031A2 (en) | 1998-10-23 | 1999-10-25 | Axially activated hemostasis valve with lumen size selection |
CA002318344A CA2318344A1 (en) | 1998-10-23 | 1999-10-25 | Axially activated hemostasis valve with lumen size selection |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10538498P | 1998-10-23 | 1998-10-23 | |
US60/105,384 | 1998-10-23 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000024453A2 true WO2000024453A2 (en) | 2000-05-04 |
WO2000024453A3 WO2000024453A3 (en) | 2000-08-10 |
Family
ID=22305533
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/025010 WO2000024453A2 (en) | 1998-10-23 | 1999-10-25 | Axially activated hemostasis valve with lumen size selection |
Country Status (4)
Country | Link |
---|---|
US (1) | US6458103B1 (en) |
EP (1) | EP1042031A2 (en) |
CA (1) | CA2318344A1 (en) |
WO (1) | WO2000024453A2 (en) |
Cited By (3)
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US7967790B2 (en) | 2009-09-01 | 2011-06-28 | Pacesetter, Inc. | Hemostasis valve with iris seal |
AU2012201577B2 (en) * | 2011-03-18 | 2013-10-24 | Cook Medical Technologies Llc | Adjustable diameter hemostatic valve |
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- 1999-10-22 US US09/425,466 patent/US6458103B1/en not_active Expired - Lifetime
- 1999-10-25 CA CA002318344A patent/CA2318344A1/en not_active Abandoned
- 1999-10-25 WO PCT/US1999/025010 patent/WO2000024453A2/en not_active Application Discontinuation
- 1999-10-25 EP EP99970933A patent/EP1042031A2/en not_active Withdrawn
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006507859A (en) * | 2002-08-21 | 2006-03-09 | アロウ・インターナショナル・インコーポレイテッド | Catheter connector with pivot lever spring latch |
US7967790B2 (en) | 2009-09-01 | 2011-06-28 | Pacesetter, Inc. | Hemostasis valve with iris seal |
AU2012201577B2 (en) * | 2011-03-18 | 2013-10-24 | Cook Medical Technologies Llc | Adjustable diameter hemostatic valve |
US9440059B2 (en) | 2011-03-18 | 2016-09-13 | Cook Medical Technologies Llc | Adjustable diameter hemostatic valve |
Also Published As
Publication number | Publication date |
---|---|
WO2000024453A3 (en) | 2000-08-10 |
US6458103B1 (en) | 2002-10-01 |
EP1042031A2 (en) | 2000-10-11 |
CA2318344A1 (en) | 2000-05-04 |
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