WO2000044940A3 - Nucleic acid sequences for detecting genetic markers for cancer in a biological sample - Google Patents

Nucleic acid sequences for detecting genetic markers for cancer in a biological sample Download PDF

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Publication number
WO2000044940A3
WO2000044940A3 PCT/US2000/002270 US0002270W WO0044940A3 WO 2000044940 A3 WO2000044940 A3 WO 2000044940A3 US 0002270 W US0002270 W US 0002270W WO 0044940 A3 WO0044940 A3 WO 0044940A3
Authority
WO
WIPO (PCT)
Prior art keywords
prostate
nucleic acid
acid sequences
genetic markers
biological sample
Prior art date
Application number
PCT/US2000/002270
Other languages
French (fr)
Other versions
WO2000044940A2 (en
Inventor
Richard C Harvey
Thomas J Clark Jr
Original Assignee
Gen Probe Inc
Richard C Harvey
Thomas J Clark Jr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Probe Inc, Richard C Harvey, Thomas J Clark Jr filed Critical Gen Probe Inc
Priority to CA2360073A priority Critical patent/CA2360073C/en
Priority to AU34755/00A priority patent/AU767587B2/en
Priority to JP2000596180A priority patent/JP4495349B2/en
Priority to EP00913284A priority patent/EP1151142A2/en
Publication of WO2000044940A2 publication Critical patent/WO2000044940A2/en
Publication of WO2000044940A3 publication Critical patent/WO2000044940A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Abstract

Nucleic acid sequences for detecting the presence of nucleic acids, particularly mRNA, encoding human prostate-associated genetic markers encoding prostate-specific antigen (PSA), prostate specific membrane antigen (PSMA) or human kallikrein 2 (hK2) are disclosed. Preferred combinations of nucleic acid sequences amplifying and detecting the prostate-associated genetic markers RNA, used in methods that include amplification of the target sequences and detection of the amplified sequences are disclosed. Methods of detecting the presence of prostate-associated genetic marker nucleic acids, particularly mRNA, in a biological sample of non-prostate origin are disclosed.
PCT/US2000/002270 1999-01-28 2000-01-28 Nucleic acid sequences for detecting genetic markers for cancer in a biological sample WO2000044940A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA2360073A CA2360073C (en) 1999-01-28 2000-01-28 Probes and primers for detecting prostate specific antigen (psa) in a biological sample
AU34755/00A AU767587B2 (en) 1999-01-28 2000-01-28 Nucleic acid sequences for detecting genetic markers for cancer in a biological sample
JP2000596180A JP4495349B2 (en) 1999-01-28 2000-01-28 Nucleic acid sequences for detecting cancer genetic markers in biological samples
EP00913284A EP1151142A2 (en) 1999-01-28 2000-01-28 Nucleic acid sequences for detecting genetic markers for cancer in a biological sample

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11764099P 1999-01-28 1999-01-28
US60/117,640 1999-01-28

Publications (2)

Publication Number Publication Date
WO2000044940A2 WO2000044940A2 (en) 2000-08-03
WO2000044940A3 true WO2000044940A3 (en) 2000-12-07

Family

ID=22374015

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/002270 WO2000044940A2 (en) 1999-01-28 2000-01-28 Nucleic acid sequences for detecting genetic markers for cancer in a biological sample

Country Status (6)

Country Link
US (5) US6551778B1 (en)
EP (1) EP1151142A2 (en)
JP (1) JP4495349B2 (en)
AU (1) AU767587B2 (en)
CA (1) CA2360073C (en)
WO (1) WO2000044940A2 (en)

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JP5340167B2 (en) 2006-12-21 2013-11-13 ジェン−プロウブ インコーポレイテッド Methods and compositions for nucleic acid amplification
US20110091883A1 (en) * 2009-02-18 2011-04-21 Helicos Biosciences Corporation Methods for analyzing minute cellular nucleic acids
CN102414554B (en) * 2009-04-22 2014-11-26 威斯康星校友研究基金会 Analyte detection using liquid crystals
US9169512B2 (en) 2009-07-01 2015-10-27 Gen-Probe Incorporated Methods and compositions for nucleic acid amplification
SG10201912361VA (en) * 2010-07-27 2020-02-27 Genomic Health Inc Method for using gene expression to determine prognosis of prostate cancer
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US9255293B2 (en) 2010-11-01 2016-02-09 Gen-Probe Incorporated Integrated capture and amplification of target nucleic acid for sequencing
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SG11201608035UA (en) 2014-03-28 2016-10-28 Opko Diagnostics Llc Compositions and methods related to diagnosis of prostate cancer
DK3253800T3 (en) 2015-03-27 2021-05-31 Opko Diagnostics Llc Prostate antigen standards and use thereof
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CN111518170A (en) * 2020-05-09 2020-08-11 新乡医学院 FRET-based PSA fluorescent probe, preparation method and application thereof
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Also Published As

Publication number Publication date
CA2360073A1 (en) 2000-08-03
AU3475500A (en) 2000-08-18
US20030104448A1 (en) 2003-06-05
US20050118630A1 (en) 2005-06-02
EP1151142A2 (en) 2001-11-07
US6811985B2 (en) 2004-11-02
US7267956B2 (en) 2007-09-11
JP4495349B2 (en) 2010-07-07
WO2000044940A2 (en) 2000-08-03
US20090035773A1 (en) 2009-02-05
AU767587B2 (en) 2003-11-20
US20080026398A1 (en) 2008-01-31
US6551778B1 (en) 2003-04-22
CA2360073C (en) 2011-01-18
JP2002535014A (en) 2002-10-22

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