WO2000060051A3 - Arpe-19 as a platform cell line for encapsulated cell-based delivery - Google Patents
Arpe-19 as a platform cell line for encapsulated cell-based delivery Download PDFInfo
- Publication number
- WO2000060051A3 WO2000060051A3 PCT/US2000/009150 US0009150W WO0060051A3 WO 2000060051 A3 WO2000060051 A3 WO 2000060051A3 US 0009150 W US0009150 W US 0009150W WO 0060051 A3 WO0060051 A3 WO 0060051A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- arpe
- cell line
- cell
- based delivery
- encapsulated
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/126—Immunoprotecting barriers, e.g. jackets, diffusion chambers
- A61K2035/128—Immunoprotecting barriers, e.g. jackets, diffusion chambers capsules, e.g. microcapsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Abstract
Priority Applications (12)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0009562-1A BR0009562A (en) | 1999-04-06 | 2000-04-06 | arp- 19 as an encapsulated cell-based release platform cell line |
US09/958,040 US7115257B1 (en) | 1999-04-06 | 2000-04-06 | ARPE-19 as a platform cell line for encapsulated cell-based delivery |
DE60011761T DE60011761T2 (en) | 1999-04-06 | 2000-04-06 | ARPE-19 AS PLATFORM CELL LINE FOR THE ADMINISTRATION OF ENCAPSULATED CELLS |
EP00923144A EP1171573B1 (en) | 1999-04-06 | 2000-04-06 | Arpe-19 as a platform cell line for encapsulated cell-based delivery |
CA2365532A CA2365532C (en) | 1999-04-06 | 2000-04-06 | Arpe-19 as a platform cell line for encapsulated cell-based delivery |
AU43319/00A AU773387B2 (en) | 1999-04-06 | 2000-04-06 | ARPE-19 as a platform cell line for encapsulated cell-based delivery |
JP2000609543A JP4954374B2 (en) | 1999-04-06 | 2000-04-06 | ARPE-19 as a platform cell line for encapsulated cell-based delivery |
AT00923144T ATE269715T1 (en) | 1999-04-06 | 2000-04-06 | ARPE-19 AS A CELL LINE PLATFORM FOR ADMINISTRATION OF ENCAPSULATED CELLS |
NO20014856A NO20014856D0 (en) | 1999-04-06 | 2001-10-05 | ARPE-19 as a platform cell line for encapsulated cell-based delivery |
US11/543,015 US20070071734A1 (en) | 1999-04-06 | 2006-10-03 | ARPE-19 as platform cell line for encapsulated cell-based delivery |
US12/498,737 US20090269389A1 (en) | 1999-04-06 | 2009-07-07 | ARPE-19 as a Platform Cell Line for Encapsulated Cell-Based Delivery |
US12/499,403 US20090269319A1 (en) | 1999-04-06 | 2009-07-08 | ARPE-19 as a Platform Cell Line for Encapsulated Cell-Based Delivery |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12792699P | 1999-04-06 | 1999-04-06 | |
US60/127,926 | 1999-04-06 | ||
US09/543,119 US6361771B1 (en) | 1999-04-06 | 2000-04-05 | ARPE-19 as a platform cell line for encapsulated cell-based delivery |
US09/543,119 | 2000-04-05 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/543,015 Continuation US20070071734A1 (en) | 1999-04-06 | 2006-10-03 | ARPE-19 as platform cell line for encapsulated cell-based delivery |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2000060051A2 WO2000060051A2 (en) | 2000-10-12 |
WO2000060051A8 WO2000060051A8 (en) | 2001-04-05 |
WO2000060051A3 true WO2000060051A3 (en) | 2002-03-28 |
Family
ID=26826092
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/009150 WO2000060051A2 (en) | 1999-04-06 | 2000-04-06 | Arpe-19 as a platform cell line for encapsulated cell-based delivery |
Country Status (12)
Country | Link |
---|---|
US (2) | US6361771B1 (en) |
EP (1) | EP1171573B1 (en) |
JP (2) | JP4954374B2 (en) |
AT (1) | ATE269715T1 (en) |
AU (1) | AU773387B2 (en) |
BR (1) | BR0009562A (en) |
CA (1) | CA2365532C (en) |
DE (1) | DE60011761T2 (en) |
DK (1) | DK1171573T3 (en) |
ES (1) | ES2219335T3 (en) |
NO (1) | NO20014856D0 (en) |
WO (1) | WO2000060051A2 (en) |
Families Citing this family (55)
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US6878544B2 (en) * | 1996-04-19 | 2005-04-12 | Neurotech Sa | Retinal cell lines with extended life-span and their applications |
US6593133B1 (en) * | 1998-07-06 | 2003-07-15 | Nsgene A/S | Neurotrophic factors |
US20070071734A1 (en) * | 1999-04-06 | 2007-03-29 | Weng Tao | ARPE-19 as platform cell line for encapsulated cell-based delivery |
US6361771B1 (en) * | 1999-04-06 | 2002-03-26 | Neurotech S.A. | ARPE-19 as a platform cell line for encapsulated cell-based delivery |
US7442370B2 (en) | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
US7276580B2 (en) * | 2001-03-12 | 2007-10-02 | Biogen Idec Ma Inc. | Neurotrophic factors |
WO2003033016A1 (en) * | 2001-10-16 | 2003-04-24 | Jenny Phipps | Use of neurotrophic factors for treating neurodegenerative diseases and cancer |
CA2484965A1 (en) * | 2002-04-30 | 2003-11-13 | Canadian Blood Services | Encapsulated cells to elicit immune response |
JP4571776B2 (en) * | 2002-11-05 | 2010-10-27 | Jx日鉱日石エネルギー株式会社 | Lubricating oil composition |
NZ543365A (en) | 2003-04-18 | 2009-02-28 | Biogen Idec Inc | Polymer-conjugated glycosylated neublastin |
ES2323066T3 (en) * | 2003-06-10 | 2009-07-06 | Nsgene A/S | IMPROVED SECRETION OF NEUBLASTIN. |
US7897384B2 (en) * | 2003-09-08 | 2011-03-01 | Ethicon, Inc. | Chondrocyte therapeutic delivery system |
US8257963B2 (en) | 2007-06-01 | 2012-09-04 | Depuy Mitek, Inc. | Chondrocyte container and method of use |
US7927599B2 (en) | 2003-09-08 | 2011-04-19 | Ethicon, Inc. | Chondrocyte therapeutic delivery system |
US7598059B2 (en) * | 2003-10-02 | 2009-10-06 | Biogen Idec Ma Inc. | Neublastin expression constructs |
BRPI0415563A (en) | 2003-10-20 | 2007-01-02 | Nsgene As | method for treating parkinson's disease, use of a viral vector, viral expression vector, pharmaceutical composition, isolated host cell, packaging cell line, chimeric non-human mammal, implantable cell culture device, biocompatibly capsule, method for treatment of a nervous system disease, mammalian cell, and, method for producing neurturin or a functional equivalent thereof |
US20060239966A1 (en) * | 2003-10-20 | 2006-10-26 | Tornoee Jens | In vivo gene therapy of parkinson's disease |
KR101204286B1 (en) | 2004-03-30 | 2012-11-26 | 엔에스진 에이/에스 | Therapeutic use of a growth factor, NsG33 |
KR101215697B1 (en) * | 2004-08-19 | 2012-12-28 | 바이오겐 아이덱 엠에이 인코포레이티드 | Neublastin variants |
KR101241551B1 (en) * | 2004-08-19 | 2013-03-11 | 바이오겐 아이덱 엠에이 인코포레이티드 | Refolding transforming growth factor beta family proteins |
EP1869162A1 (en) * | 2005-04-01 | 2007-12-26 | NsGene A/S | A human immortalised neural precursor cell line |
WO2006122549A2 (en) * | 2005-05-17 | 2006-11-23 | Nsgene A/S | An implantable therapy system comprising a gripping element |
WO2007042040A2 (en) * | 2005-10-11 | 2007-04-19 | Ns Gene A/S | TREATMENT OF RETINOPATHIES USING GFRα3 AGONISTS |
JP2009513584A (en) * | 2005-10-28 | 2009-04-02 | エヌエスゲーネ・アクティーゼルスカブ | Implantable biocompatible immunoisolation vehicle for delivery of GDNF |
JP5247468B2 (en) * | 2005-12-30 | 2013-07-24 | ニューロテック ユーエスエー, インコーポレイテッド | Micronized device for delivery of bioactive molecules and method of use thereof |
TWI501774B (en) | 2006-02-27 | 2015-10-01 | Biogen Idec Inc | Treatments for neurological disorders |
EP1993590B1 (en) * | 2006-03-01 | 2013-12-25 | Biogen Idec MA Inc. | Compostions and methods for administering gdnf ligand family proteins |
TWI445544B (en) * | 2007-05-01 | 2014-07-21 | Biogen Idec Inc | Compositions and methods for increasing vascularization |
WO2009020964A2 (en) * | 2007-08-08 | 2009-02-12 | Biogen Idec Ma Inc. | Anti-neublastin antibodies and uses thereof |
US20090196854A1 (en) * | 2008-02-04 | 2009-08-06 | Kytos Biosystems S.A. | Methods and compositions for use of crl 5803 cells for expression of biotherapeutics and encapsulated cell-based delivery |
US8075537B2 (en) * | 2008-08-15 | 2011-12-13 | Oxyband Technologies, Inc. | Multiple cell therapeutic diffusion device |
WO2010083842A2 (en) | 2009-01-23 | 2010-07-29 | Nsgene A/S | Expression of neuropeptides in mammalian cells |
CN102361971A (en) * | 2009-01-23 | 2012-02-22 | Ns基因公司 | Improved cell lines and their use in encapsulated cell biodelivery |
JP2012524544A (en) * | 2009-04-23 | 2012-10-18 | ニューロテック ユーエスエー, インコーポレイテッド | Cell lines producing prostaglandin F2 alpha (PGF2a) and uses thereof |
US20110111008A1 (en) * | 2009-10-08 | 2011-05-12 | Weng Tao | Use of PEDF in an Encapsulated Cell-Based Delivery System |
US20110104154A1 (en) * | 2009-10-30 | 2011-05-05 | Alcon Research, Ltd. | Single nucleotide polymorphisms and genes associated with age-related macular degeneration |
WO2012009377A2 (en) | 2010-07-12 | 2012-01-19 | University Of Southern California | Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same |
CN108079279B (en) | 2010-10-01 | 2022-04-12 | 霍巴治疗公司 | Use of nickel-line protein for treating allodynia, hyperalgesia, spontaneous pain and phantom pain |
AU2011336592A1 (en) * | 2010-12-02 | 2013-07-11 | Neurotech Usa, Inc. | Cell lines that secrete anti-angiogenic antibody-scaffolds and soluble receptors and uses thereof |
US10478206B2 (en) | 2011-04-29 | 2019-11-19 | University Of Southern California | Instruments and methods for the implantation of cell-seeded substrates |
US8877489B2 (en) | 2011-12-05 | 2014-11-04 | California Institute Of Technology | Ultrathin parylene-C semipermeable membranes for biomedical applications |
US9265813B2 (en) | 2011-10-27 | 2016-02-23 | Wellstat Ophthalmics Corporation | Vectors encoding rod-derived cone viability factor |
US9248013B2 (en) | 2011-12-05 | 2016-02-02 | California Institute Of Technology | 3-Dimensional parylene scaffold cage |
CN104640579A (en) * | 2012-05-30 | 2015-05-20 | 神经技术美国有限公司 | Cryopreserved implantable cell culture devices and uses thereof |
US20160123960A1 (en) * | 2013-06-10 | 2016-05-05 | Millennium Pharmaceuticals, Inc. | Method for preparing three-dimensional, organotypic cell cultures and uses thereof |
WO2015038669A1 (en) | 2013-09-11 | 2015-03-19 | Neurotech Usa, Inc. | Encapsulated cell therapy cartridge |
FR3014316B1 (en) * | 2013-12-10 | 2017-01-20 | Defymed | BIOARTIFICIAL ORGAN |
EP3188712A1 (en) | 2014-09-04 | 2017-07-12 | Kemijski Institut | Cell-based device for local treatment with therapeutic protein |
US10456356B2 (en) | 2015-05-27 | 2019-10-29 | Neurotech Usa, Inc. | Use of encapsulated cell therapy for treatment of ophthalmic disorders |
EP4051192A1 (en) | 2019-11-01 | 2022-09-07 | Neurotech USA, Inc. | System, apparatuses, devices, and methods for an analyte diffusive implantable device |
EP3892259A1 (en) | 2020-04-09 | 2021-10-13 | Defymed | Membranes for medical devices |
WO2021204935A1 (en) | 2020-04-09 | 2021-10-14 | Defymed | Membranes for medical devices |
WO2022011081A1 (en) | 2020-07-09 | 2022-01-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Cell lines that produce human retinoschisin proteins and uses thereof |
AU2022269279A1 (en) | 2021-05-06 | 2023-11-30 | Hoba Therapeutics Aps | Prevention and treatment of chemotherapy-induced neuropathic pain |
WO2023104960A1 (en) | 2021-12-10 | 2023-06-15 | Hoba Therapeutics Aps | Treatment of nociceptive pain |
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WO1997034586A2 (en) * | 1996-03-22 | 1997-09-25 | Cytotherapeutics, Inc. | Device and method for treating ophthalmic diseases |
WO1997044065A2 (en) * | 1996-05-20 | 1997-11-27 | Cytotherapeutics, Inc. | Device and method for encapsulated gene therapy |
WO1998040498A2 (en) * | 1997-03-10 | 1998-09-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Immunoadhesins and methods of production and use thereof |
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JPH09502620A (en) | 1993-06-23 | 1997-03-18 | ブラウン ユニヴァーシティ リサーチ ファンデーション | Method and device for sealing an implantable membrane capsule device |
EP1179350A3 (en) | 1993-08-12 | 2003-01-02 | Cytotherapeutics, Inc. | Encapsulated cell system for implantation into the human CNS |
US5550050A (en) | 1994-04-15 | 1996-08-27 | Cytotherapeutics, Inc. | Method for implanting encapsulated cells in a host |
US5641750A (en) * | 1995-11-29 | 1997-06-24 | Amgen Inc. | Methods for treating photoreceptors using glial cell line-derived neurotrophic factor (GDNF) protein product |
US6020192A (en) * | 1996-01-18 | 2000-02-01 | University Of Florida | Humanized green fluorescent protein genes and methods |
US6054142A (en) | 1996-08-01 | 2000-04-25 | Cyto Therapeutics, Inc. | Biocompatible devices with foam scaffolds |
US6303136B1 (en) | 1998-04-13 | 2001-10-16 | Neurotech S.A. | Cells or tissue attached to a non-degradable filamentous matrix encapsulated by a semi-permeable membrane |
US6361771B1 (en) * | 1999-04-06 | 2002-03-26 | Neurotech S.A. | ARPE-19 as a platform cell line for encapsulated cell-based delivery |
-
2000
- 2000-04-05 US US09/543,119 patent/US6361771B1/en not_active Expired - Lifetime
- 2000-04-06 CA CA2365532A patent/CA2365532C/en not_active Expired - Lifetime
- 2000-04-06 BR BRPI0009562-1A patent/BR0009562A/en not_active IP Right Cessation
- 2000-04-06 AU AU43319/00A patent/AU773387B2/en not_active Expired
- 2000-04-06 EP EP00923144A patent/EP1171573B1/en not_active Expired - Lifetime
- 2000-04-06 DE DE60011761T patent/DE60011761T2/en not_active Expired - Lifetime
- 2000-04-06 WO PCT/US2000/009150 patent/WO2000060051A2/en active IP Right Grant
- 2000-04-06 US US09/958,040 patent/US7115257B1/en not_active Expired - Lifetime
- 2000-04-06 JP JP2000609543A patent/JP4954374B2/en not_active Expired - Lifetime
- 2000-04-06 AT AT00923144T patent/ATE269715T1/en active
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- 2000-04-06 DK DK00923144T patent/DK1171573T3/en active
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997034586A2 (en) * | 1996-03-22 | 1997-09-25 | Cytotherapeutics, Inc. | Device and method for treating ophthalmic diseases |
WO1997044065A2 (en) * | 1996-05-20 | 1997-11-27 | Cytotherapeutics, Inc. | Device and method for encapsulated gene therapy |
WO1998040498A2 (en) * | 1997-03-10 | 1998-09-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Immunoadhesins and methods of production and use thereof |
Non-Patent Citations (1)
Title |
---|
POCHON NAM: "Gene Therapy for Amyotrophic Lateral Sclerosis (ALS) Using a Polymer Encapsulated Xenogenic Cell Line Engineered to Secrete hCNTF", HUMAN GENE THERAPY, vol. 7, 1 May 1996 (1996-05-01), pages 851 - 860, XP001031178 * |
Also Published As
Publication number | Publication date |
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US6361771B1 (en) | 2002-03-26 |
DE60011761D1 (en) | 2004-07-29 |
US7115257B1 (en) | 2006-10-03 |
JP2003524621A (en) | 2003-08-19 |
ES2219335T3 (en) | 2004-12-01 |
DE60011761T2 (en) | 2005-08-04 |
BR0009562A (en) | 2007-05-29 |
CA2365532A1 (en) | 2000-10-12 |
CA2365532C (en) | 2012-11-06 |
ATE269715T1 (en) | 2004-07-15 |
NO20014856D0 (en) | 2001-10-05 |
JP4954374B2 (en) | 2012-06-13 |
AU773387B2 (en) | 2004-05-27 |
EP1171573A1 (en) | 2002-01-16 |
WO2000060051A2 (en) | 2000-10-12 |
JP2011074079A (en) | 2011-04-14 |
AU4331900A (en) | 2000-10-23 |
WO2000060051A8 (en) | 2001-04-05 |
EP1171573B1 (en) | 2004-06-23 |
DK1171573T3 (en) | 2004-09-27 |
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