WO2000064345A1 - Respiratory ventilator with automatic flow calibration - Google Patents

Respiratory ventilator with automatic flow calibration Download PDF

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Publication number
WO2000064345A1
WO2000064345A1 PCT/US2000/010531 US0010531W WO0064345A1 WO 2000064345 A1 WO2000064345 A1 WO 2000064345A1 US 0010531 W US0010531 W US 0010531W WO 0064345 A1 WO0064345 A1 WO 0064345A1
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WO
WIPO (PCT)
Prior art keywords
flow
gas
consecutive
values
composite
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Application number
PCT/US2000/010531
Other languages
French (fr)
Inventor
Anthony Fiorenza
John Macdonald
Original Assignee
Bird Products Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bird Products Corporation filed Critical Bird Products Corporation
Priority to AU42507/00A priority Critical patent/AU4250700A/en
Publication of WO2000064345A1 publication Critical patent/WO2000064345A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/021—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes operated by electrical means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/003—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter
    • A61M2016/0033—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical
    • A61M2016/0039—Accessories therefor, e.g. sensors, vibrators, negative pressure with a flowmeter electrical in the inspiratory circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/70—General characteristics of the apparatus with testing or calibration facilities
    • A61M2205/702—General characteristics of the apparatus with testing or calibration facilities automatically during use

Definitions

  • This invention relates in general to respiratory ventilators, and in particular to a respiratory ventilator having automatic flow calibration of respiratory gas delivered in accord with immediately preceding breath data.
  • Certain respiratory diseases not only require patient special care with respect to physical activity and attendant exertion levels, but also require specialized mechanical augmentation to permit the patient to simply accomplish the act of breathing.
  • lung disfunction, lung tissue degradation, autonomic nervous system disability, etc. can significantly interfere with proper inhalation and exhalation action and thereby deprive an individual of adequate oxygenation and attendant carbon dioxide removal
  • employment of a ventilator for positive respiratory regulation can result in a highly beneficial contribution toward life quality.
  • such ventilator therapy can be administered in association with physical activity-monitoring to thereby provide a treatment program to the patient that achieves improved comfort in day-to-day functions along with medically acceptable respiratory levels .
  • Ventilators presently in service generally operate under constant parameters that are pre-set such that inhalation and expiration of air or oxygen-enriched air does not automatically vary, but, instead, can be changed manually if a health care provider in charge of a treatment program determines such modification is desired. Therefore, volume, pressure, and delivery duration of inspiratory air or oxygen-enriched air are quantitatively estimated in accord with standard expectations usually present under a majority of circumstances in similarly- situated patients. While these parameters may adequately serve most patients most of the time, any patients whose needs do not fit expectations must endure at least partially ineffective ventilation until manual readjustment of the ventilator can be completed.
  • Another object of the present invention is to provide a ventilator whose respiratory sensor member comparatively monitors incremental exhalation flow parameters during a single exhalation and automatically calibrates ventilator output to maintain or change such output in accord with such exhalation parameters.
  • Yet another object of the present invention is to provide a ventilator whose calibrateable parameters include volume, pressure, and delivery-duration of air or oxygen- enriched air as administered to a patient.
  • the present invention is a respiratory ventilator for monitoring breath flow and automatically regulating and calibrating respiration gas flow delivery in accord with such monitored breath flow.
  • the ventilator first comprises a respiratory gas delivery member having a calibrateable gas flow adjuster and a calibrateable gas pressure adjuster that regulate delivery of respiratory gas.
  • the ventilator comprises a gas flow calibration member m communication with the gas flow adjuster and gas pressure adjuster for calibrating these adjusters to thereby regulate delivery of respiratory gas.
  • the gas flow calibration member first comprises a reader component for recording mspiratory gas volume, exhalation gas volume, and exhalation time, and for measuring a plurality of incremental exhalation gas flow values m a plurality of incremental time periods during a single exhalation and averaging as a set of consecutive flow values a pre- selected number of these flow values.
  • the gas flow calibration member comprises a composite calculator component for determining an average composite flow value of a plurality of consecutive sets of flow values and thereafter determining an average aggregate flow value of a plurality of consecutive composite flow values.
  • the composite calculator component additionally determines a volume flow calibration value as the difference between inspired and exhaled gas volume divided by exhalation time.
  • the gas flow calibration member comprises a scanner calculator component for scanning in reverse order the plurality of consecutive composite flow values and calculating a new flow calibration value where a preselected number of consecutive composite flow values fall within a pre-selected flow rate. Thereafter, the gas flow adjuster and gas pressure adjuster are calibrated in accord with the determined new flow calibration value.
  • the scanner calculator component calculates a new flow calibration value where 60 consecutive composite flow values fall within a flow rate of ⁇ 2.5 liters per minute per millisecond, or where less than 60 consecutive composite flow values fall within a flow rate of ⁇ 2.5 liters per minute per millisecond.
  • certain criteria must be met, and include (1) an existing flow calibration value that is greater than an existing bias flow plus 2.5 liters per minute, (n) a volume flow calibration value that is less than the bias flow plus 2.5 liters per minute, and (m) the existing flow calibration value minus the volume flow calibration value must be greater than 3.1 liters per minute.
  • the gas flow adjuster and gas pressure adjuster are calibrated to a flow calibration value equal to the volume flow calibration value minus 1.0 liter per minute.
  • the present invention additionally includes methodology as exemplified m the operation of the ventilator for sensing untoward respiratory activity and thereafter responding to such activity.
  • the present ventilator and methodology comparatively monitors incremental exhalation flow parameters during consecutive single exhalations and automatically calibrates ventilator output to maintain or change such output in accord with these exhalation parameters and the thereby reflected needs of a patient.
  • Figure 1 is a flow chart defining ventilator operation and respiratory gas flow calibration methodology.
  • a respiratory ventilator 10 is conventionally equipped with a respiratory gas delivery member 12 and a gas flow calibration member 14.
  • Gas delivery from the delivery member 12 to a patient is regulated by a standard calibrateable gas flow adjuster and a standard calibrateable gas pressure adjuster to thereby maintain a desired flow, defined throughout this application as the volume of gas per unit of time, of air, oxygen enriched air, or the like, to a patient.
  • the gas flow calibration member 14 has a reader component 16, a composite calculator component 18, and a scanner calculator component 20 all conventionally cooperatively networked such that data is shared among all three components 16, 18, 20.
  • the reader component 16 measures a plurality of incremental exhalation gas flow values in a plurality of two millisecond timer periods during breath exhalation, and thereafter averaging a series of three consecutive flow values to produce at least 15 consecutive sets.
  • the composite calculator component 18 receives the 15 consecutive sets of flow values to first average these values to thereby determine an average composite flow value and to second determine an average aggregate flow value derived from the averaging a plurality of average composite flow values.
  • the composite calculator component 18 additionally determines a volume flow calibration value calculated as the difference between inspired and exhaled gas volume divided by exhalation time.
  • Data from the composite calculator component 18 is conventionally transmitted to the scanner calculator component 20 where initial scanning is performed in reverse order on the plurality of composite flow values to calculate a new flow calibration value on data under "Option One" 22 where 60 consecutive composite flow values fall within a flow rate of ⁇ 2.5 liters per minute per millisecond.
  • Such calibration value is transmitted to the gas flow calibration member 14 for subsequent appropriate calibration of the gas flow and/or gas pressure adjuster (s) of the gas delivery member 12 and ultimate calibrated output from the ventilator 10.
  • a flow calibration value equal to the volume flow calibration value minus 1.0 liter per minute is transmitted to the gas flow calibration member 14 for subsequent appropriate calibration of the gas flow and/or gas pressure adjuster (s) of the gas delivery member 12 and ultimate calibrated output from the ventilator 10 m the same manner as earlier related.

Abstract

This invention is a respiratory ventilator (10), and methodology thereof for automatically calibrating respiration gas flow delivery. The ventilator includes a gas flow calibration member (14) having a reader component (16) for recording inspiratory, and exhalation gas volume with exhalation time, and for measuring a plurality of incremental exhalation gas flow values in a plurality of incremental time periods during a single exhalation. The gas flow calibration member (14) includes a composite component (14) for determining an average of consecutive composite flow values, and a scanner calculator component (20) for scanning in reverse order the plurality of consecutive composite flow values, and calculating a new flow calibration value where a preselected number of consecutive composite flow values fall within a pre-selected flow rate. Thereafter, the gas delivery member (12) is calibrated in accord with the determined new flow calibration value.

Description

RESPIRATORY VENTILATOR WITH AUTOMATIC FLOW CALIBRATION
CROSS-REFERENCE TO RELATED APPLICATIONS (Not Applicable)
STATEMENT RE: FEDERALLY SPONSORED RESEARCH/DEVELOPMENT (Not Applicable)
BACKGROUND OF THE INVENTION
This invention relates in general to respiratory ventilators, and in particular to a respiratory ventilator having automatic flow calibration of respiratory gas delivered in accord with immediately preceding breath data. Certain respiratory diseases not only require patient special care with respect to physical activity and attendant exertion levels, but also require specialized mechanical augmentation to permit the patient to simply accomplish the act of breathing. Thus, while lung disfunction, lung tissue degradation, autonomic nervous system disability, etc. can significantly interfere with proper inhalation and exhalation action and thereby deprive an individual of adequate oxygenation and attendant carbon dioxide removal, employment of a ventilator for positive respiratory regulation can result in a highly beneficial contribution toward life quality. As required, and in accord with actual maladies encountered, such ventilator therapy can be administered in association with physical activity-monitoring to thereby provide a treatment program to the patient that achieves improved comfort in day-to-day functions along with medically acceptable respiratory levels .
Ventilators presently in service generally operate under constant parameters that are pre-set such that inhalation and expiration of air or oxygen-enriched air does not automatically vary, but, instead, can be changed manually if a health care provider in charge of a treatment program determines such modification is desired. Therefore, volume, pressure, and delivery duration of inspiratory air or oxygen-enriched air are quantitatively estimated in accord with standard expectations usually present under a majority of circumstances in similarly- situated patients. While these parameters may adequately serve most patients most of the time, any patients whose needs do not fit expectations must endure at least partially ineffective ventilation until manual readjustment of the ventilator can be completed. Further, of course, any momentary change of respiratory needs such as that encountered in momentary exertion for whatever reason is not addressed by a ventilator whose delivery capabilities can be modified only through manual adjustment unless a technician just happens to be present. In view of these limitations, it is apparent that a need is present for a ventilator apparatus that is more responsive to patient needs. It is therefore a primary object of the present invention to provide a ventilator that is capable of sensing untoward respiratory activity and thereafter responding to such activity.
Another object of the present invention is to provide a ventilator whose respiratory sensor member comparatively monitors incremental exhalation flow parameters during a single exhalation and automatically calibrates ventilator output to maintain or change such output in accord with such exhalation parameters.
Yet another object of the present invention is to provide a ventilator whose calibrateable parameters include volume, pressure, and delivery-duration of air or oxygen- enriched air as administered to a patient.
These and other objects of the present invention will become apparent throughout the description thereof which now follows.
BRIEF SUMMARY OF THE INVENTION
The present invention is a respiratory ventilator for monitoring breath flow and automatically regulating and calibrating respiration gas flow delivery in accord with such monitored breath flow. The ventilator first comprises a respiratory gas delivery member having a calibrateable gas flow adjuster and a calibrateable gas pressure adjuster that regulate delivery of respiratory gas. Second, the ventilator comprises a gas flow calibration member m communication with the gas flow adjuster and gas pressure adjuster for calibrating these adjusters to thereby regulate delivery of respiratory gas. The gas flow calibration member first comprises a reader component for recording mspiratory gas volume, exhalation gas volume, and exhalation time, and for measuring a plurality of incremental exhalation gas flow values m a plurality of incremental time periods during a single exhalation and averaging as a set of consecutive flow values a pre- selected number of these flow values. Second, the gas flow calibration member comprises a composite calculator component for determining an average composite flow value of a plurality of consecutive sets of flow values and thereafter determining an average aggregate flow value of a plurality of consecutive composite flow values. The composite calculator component additionally determines a volume flow calibration value as the difference between inspired and exhaled gas volume divided by exhalation time. Third, the gas flow calibration member comprises a scanner calculator component for scanning in reverse order the plurality of consecutive composite flow values and calculating a new flow calibration value where a preselected number of consecutive composite flow values fall within a pre-selected flow rate. Thereafter, the gas flow adjuster and gas pressure adjuster are calibrated in accord with the determined new flow calibration value.
In a preferred embodiment, the scanner calculator component calculates a new flow calibration value where 60 consecutive composite flow values fall within a flow rate of ±2.5 liters per minute per millisecond, or where less than 60 consecutive composite flow values fall within a flow rate of ±2.5 liters per minute per millisecond. In the latter event, certain criteria must be met, and include (1) an existing flow calibration value that is greater than an existing bias flow plus 2.5 liters per minute, (n) a volume flow calibration value that is less than the bias flow plus 2.5 liters per minute, and (m) the existing flow calibration value minus the volume flow calibration value must be greater than 3.1 liters per minute. When all three qualifying conditions are met, the gas flow adjuster and gas pressure adjuster are calibrated to a flow calibration value equal to the volume flow calibration value minus 1.0 liter per minute.
The present invention additionally includes methodology as exemplified m the operation of the ventilator for sensing untoward respiratory activity and thereafter responding to such activity. Thus, the present ventilator and methodology comparatively monitors incremental exhalation flow parameters during consecutive single exhalations and automatically calibrates ventilator output to maintain or change such output in accord with these exhalation parameters and the thereby reflected needs of a patient.
BRIEF DESCRIPTION OF THE DRAWING
An illustrative and presently preferred embodiment of the invention is shown m the accompanying drawings in which:
Figure 1 is a flow chart defining ventilator operation and respiratory gas flow calibration methodology.
DETAILED DESCRIPTION OF THE INVENTION Referring to the drawing figure, a respiratory ventilator 10 is conventionally equipped with a respiratory gas delivery member 12 and a gas flow calibration member 14. Gas delivery from the delivery member 12 to a patient is regulated by a standard calibrateable gas flow adjuster and a standard calibrateable gas pressure adjuster to thereby maintain a desired flow, defined throughout this application as the volume of gas per unit of time, of air, oxygen enriched air, or the like, to a patient. The gas flow calibration member 14 has a reader component 16, a composite calculator component 18, and a scanner calculator component 20 all conventionally cooperatively networked such that data is shared among all three components 16, 18, 20. In addition to recording inspiratory and exhalation gas volume of an individual breath along with exhalation time for that breath, the reader component 16 measures a plurality of incremental exhalation gas flow values in a plurality of two millisecond timer periods during breath exhalation, and thereafter averaging a series of three consecutive flow values to produce at least 15 consecutive sets. The composite calculator component 18 then receives the 15 consecutive sets of flow values to first average these values to thereby determine an average composite flow value and to second determine an average aggregate flow value derived from the averaging a plurality of average composite flow values. The composite calculator component 18 additionally determines a volume flow calibration value calculated as the difference between inspired and exhaled gas volume divided by exhalation time.
Data from the composite calculator component 18 is conventionally transmitted to the scanner calculator component 20 where initial scanning is performed in reverse order on the plurality of composite flow values to calculate a new flow calibration value on data under "Option One" 22 where 60 consecutive composite flow values fall within a flow rate of ±2.5 liters per minute per millisecond. Such calibration value is transmitted to the gas flow calibration member 14 for subsequent appropriate calibration of the gas flow and/or gas pressure adjuster (s) of the gas delivery member 12 and ultimate calibrated output from the ventilator 10. When less than 60 consecutive composite flow values fall within a flow rate of ±2.5 liters per minute per millisecond, data from that exhalation is ignored and no new calibration value is calculated unless all of the following are present as defined in "Option Two" 24: (i) the existing flow calibration value is greater than the existing bias flow plus 2.5 liters per minute, (n) the volume flow calibration value is less than the bias flow plus 2.5 liters per minute, and (m) the existing flow calibration value minus the volume flow calibration value is greater than 3.1 liters per minute. When all the criteria of (ι), (11), and (m) are present, a flow calibration value equal to the volume flow calibration value minus 1.0 liter per minute is transmitted to the gas flow calibration member 14 for subsequent appropriate calibration of the gas flow and/or gas pressure adjuster (s) of the gas delivery member 12 and ultimate calibrated output from the ventilator 10 m the same manner as earlier related.
In operation, all of the described events are performed automatically during every breath. Consequently, a patient whose respiratory maladies are addressed by the ventilator 10 can experience a generally consistent respiratory pattern generally irrespective of extraneous factors that may include nebulizer use, random exertion, altitude changes, and other impinging influences. Additionally, because both gas flow and gas pressure are under consideration for calibration, a proper flow can be delivered to a patient where pressurized force is indicated for sufficient respiratory gas inhalation. The ventilator and operational methodology here described thereby produces a life quality for respiratory disease sufferers.
While an illustrative and presently preferred embodiment of the invention has been described in detail herein, it is to be understood that the inventive concepts may be otherwise variously embodied and employed and that the appended claims are intended to be construed to include such variations except insofar as limited by the prior art.

Claims

1. A respiratory ventilator for monitoring breath flow and automatically regulating and calibrating respiration gas flow delivery in accord with such monitored breath flow, the ventilator comprising: a) a respiratory gas delivery member having a calibrateable gas flow adjuster and a calibrateable gas pressure adjuster, wherein said flow and pressure adjusters regulate delivery of respiratory gas; and b) a gas flow calibration member m communication with the gas flow adjuster and gas pressure adjuster for calibrating said adjusters to thereby regulate delivery of respiratory gas, said gas flow calibration member comprising: 1) a reader component for recording mspiratory gas volume, exhalation gas volume, and exhalation time of an individual breath, and for measuring a plurality of incremental exhalation gas flow values in a plurality of incremental time periods during exhalation of said individual breath and averaging as a set of consecutive flow values a pre-selected number of said flow values;
2) a composite calculator component for determining an average composite flow value of a plurality of consecutive sets of flow values and thereafter determining and saving an average aggregate flow value of a plurality of consecutive composite flow values, and additionally for determining a volume flow calibration value as the difference between inspired and exhaled gas volume divided by exhalation time; and
3) a scanner calculator component for scanning m reverse order the plurality of consecutive composite flow values and calculating a new flow calibration value where a pre-selected number of consecutive composite flow values fall with n a pre-selected flow rate, and thereafter for calibration of the gas flow adjuster and gas pressure adjuster.
2. A respiratory ventilator as claimed in Claim 1 wherein each incremental time period is two milliseconds.
3. A respiratory ventilator as claimed m Claim 2 wherein the pre-selected number of flow values of each set is determined from three consecutive flow values..
4. A respiratory ventilator as claimed in Claim 3 wherein the average composite flow value is determined from
15 consecutive sets.
5. A respiratory ventilator as claimed m Claim 4 wherein the pre-selected number of composite flow values for calculating a new flow calibration is 60 and the pre- selected flow rate is ±2.5 liters per minute per millisecond.
6. A respiratory ventilator for monitoring breath flow and automatically regulating and calibrating respiration gas flow delivery m accord with such monitored breath flow, the ventilator comprising: a) a respiratory gas delivery member having a calibrateable gas flow adjuster and a calibrateable gas pressure adjuster, wherein said flow and pressure adjusters regulate delivery of respiratory gas; and b) a gas flow calibration member m communication with the gas flow adjuster and gas pressure adjuster for calibrating said adjusters to thereby regulate delivery of respiratory gas, said gas flow calibration member comprising: 1) a reader component for recording inspiratory gas volume, exhalation gas volume, and exhalation time of an individual breath, and for measuring a plurality of incremental exhalation gas flow values in a plurality of consecutive two millisecond time periods during exhalation of said individual breath and averaging as a set of flow values three consecutive flow values; 2) a composite calculator component for determining an average composite flow value of 15 consecutive sets of flow values and thereafter determining and saving an average aggregate flow value of a plurality of consecutive composite flow values, and additionally for determining a volume flow calibration value as the difference between inspired and exhaled gas volume divided by exhalation time; and 3) a scanner calculator component for scanning in reverse order the plurality of composite flow values and calculating a new flow calibration value where 60 consecutive composite flow values fall within a flow rate of ±2.5 liters per minute per millisecond or where less than 60 consecutive composite flow values fall within a flow rate of ±2.5 liters per minute per millisecond and wherein (l) an existing flow calibration value is greater than an existing bias flow plus 2.5 liters per minute, (n) the volume flow calibration value is less than said bias flow plus 2.5 liters per minute, and (m) said existing flow calibration value minus said volume flow calibration value is greater than 3.1 liters per minute, and thereafter for calibration of the gas flow adjuster and gas pressure adjuster to a flow calibration value equal to said volume flow calibration value minus 1.0 liter per minute.
7. A method for monitoring breath flow and regulating and calibrating respiration gas flow delivery by a ventilator in accord with such monitored breath flow, the method comprising: a) activating a ventilator comprising a respiratory gas delivery member having a calibrateable gas flow adjuster and a calibrateable gas pressure adjuster, wherein said flow and pressure adjusters regulate delivery of respiratory gas; b) recording mspiratory gas volume, exhalation gas volume, and exhalation time of an individual breath, and measuring a plurality of incremental exhalation gas flow values in a plurality of incremental time periods during exhalation of said individual breath and averaging as a set of consecutive flow values a pre-selected number of said flow values; c) determining an average composite flow value of a plurality of consecutive sets of flow values and thereafter determining and saving an average aggregate flow value of a plurality of consecutive composite flow values, and additionally determining a volume flow calibration value as the difference between inspired and exhaled gas volume divided by exhalation time ; d) scanning in reverse order the plurality of consecutive composite flow values and calculating a new flow calibration value where a pre-selected number of consecutive composite flow values fall within a pre-selected flow rate; and e) automatically transmitting the new flow calibration value to the gas flow adjuster and gas pressure adjuster of the ventilator to thereby regulate delivery of respiratory gas.
8. A method for monitoring breath flow and regulating and calibrating respiration gas flow delivery as claimed m Claim 7 wherein each incremental time period is two milliseconds .
9. A method for monitoring breath flow and regulating and calibrating respiration gas flow delivery as claimed in
Claim 8 wherein the pre-selected number of flow values of each set is determined from three consecutive flow values..
10. A method for monitoring breath flow and regulating and calibrating respiration gas flow delivery as claimed m Claim 9 wherein the average composite flow value is determined from 15 consecutive sets.
11. A method for monitoring breath flow and regulating and calibrating respiration gas flow delivery as claimed m Claim 10 wherein the pre-selected number of composite flow values for calculating a new flow calibration is 60 and the pre-selected flow rate is ±2.5 liters per minute per millisecond.
12. A method for monitoring breath flow and regulating and calibrating respiration gas flow delivery by a ventilator m accord with such monitored breath flow, the method comprising: a) recording inspiratory gas volume, exhalation gas volume, and exhalation time of an individual breath, and measuring a plurality of incremental exhalation gas flow values in a plurality of consecutive two millisecond time periods during exhalation of said individual breath and averaging as a set of flow values three consecutive flow values;
2) determining an average composite flow value of 15 consecutive sets of flow values and thereafter determining and saving an average aggregate flow value of a plurality of consecutive composite flow values, and additionally determining a volume flow calibration value as the difference between inspired and exhaled gas volume divided by exhalation time; and
3) scanning in reverse order the plurality of composite flow values and calculating a new flow calibration value where 60 consecutive composite flow values fall within a flow rate of
±2.5 liters per minute per millisecond or where less than 60 consecutive composite flow values fall within a flow rate of ±2.5 liters per minute per millisecond and wherein (i) an existing flow calibration value is greater than an existing bias flow plus 2.5 liters per minute, (n) the volume flow calibration value is less than said bias flow plus 2.5 liters per minute, and (m) said existing flow calibration value minus said volume flow calibration value is greater than 3.1 liters per minute, and thereafter calibrating a gas flow adjuster and gas pressure adjuster of the ventilator to a flow calibration value equal to said volume flow calibration value minus 1.0 liter per minute.
PCT/US2000/010531 1999-04-26 2000-04-19 Respiratory ventilator with automatic flow calibration WO2000064345A1 (en)

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US09/299,780 US6135967A (en) 1999-04-26 1999-04-26 Respiratory ventilator with automatic flow calibration

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011079752A1 (en) * 2009-12-31 2011-07-07 北京谊安医疗系统股份有限公司 Method, device and system for detecting medical equipment
JP2012512686A (en) * 2008-12-19 2012-06-07 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ System and method for treating lung disease using positive airway pressure support
CN111504387A (en) * 2020-05-19 2020-08-07 南京舒普医疗科技有限公司 Breathing machine calibration equipment and breathing machine calibration system

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9903467D0 (en) * 1999-09-24 1999-09-24 Siemens Elema Ab Feedback control of mechanical breathing aid gas flow
US6666209B2 (en) 2001-02-20 2003-12-23 3M Innovative Properties Company Method and system of calibrating air flow in a respirator system
KR20030065791A (en) * 2002-02-01 2003-08-09 (주)바이오텔 System for providing oxygen for providing perfumed ingredients in medicine
US6668850B2 (en) * 2002-01-08 2003-12-30 Biotel Co., Ltd. Apparatus for supplying oxygen
US9901288B2 (en) * 2002-03-14 2018-02-27 Omegapoint Systems, Llc Methods of detecting gaseous component levels in a breath
US20030236489A1 (en) 2002-06-21 2003-12-25 Baxter International, Inc. Method and apparatus for closed-loop flow control system
FR2858236B1 (en) 2003-07-29 2006-04-28 Airox DEVICE AND METHOD FOR SUPPLYING RESPIRATORY GAS IN PRESSURE OR VOLUME
US8457706B2 (en) 2008-05-16 2013-06-04 Covidien Lp Estimation of a physiological parameter using a neural network
CN102056539B (en) 2008-06-06 2015-10-07 柯惠有限合伙公司 For making great efforts with patient the system and method that carries out pro rata taking a breath
US8302602B2 (en) 2008-09-30 2012-11-06 Nellcor Puritan Bennett Llc Breathing assistance system with multiple pressure sensors
US8434479B2 (en) 2009-02-27 2013-05-07 Covidien Lp Flow rate compensation for transient thermal response of hot-wire anemometers
US8439036B2 (en) 2009-12-01 2013-05-14 Covidien Lp Exhalation valve assembly with integral flow sensor
US8439037B2 (en) 2009-12-01 2013-05-14 Covidien Lp Exhalation valve assembly with integrated filter and flow sensor
US8469030B2 (en) 2009-12-01 2013-06-25 Covidien Lp Exhalation valve assembly with selectable contagious/non-contagious latch
US8469031B2 (en) 2009-12-01 2013-06-25 Covidien Lp Exhalation valve assembly with integrated filter
USD655809S1 (en) 2010-04-27 2012-03-13 Nellcor Puritan Bennett Llc Valve body with integral flow meter for an exhalation module
USD653749S1 (en) 2010-04-27 2012-02-07 Nellcor Puritan Bennett Llc Exhalation module filter body
USD655405S1 (en) 2010-04-27 2012-03-06 Nellcor Puritan Bennett Llc Filter and valve body for an exhalation module
US8714154B2 (en) 2011-03-30 2014-05-06 Covidien Lp Systems and methods for automatic adjustment of ventilator settings
US9629971B2 (en) 2011-04-29 2017-04-25 Covidien Lp Methods and systems for exhalation control and trajectory optimization
US9364624B2 (en) 2011-12-07 2016-06-14 Covidien Lp Methods and systems for adaptive base flow
US9498589B2 (en) 2011-12-31 2016-11-22 Covidien Lp Methods and systems for adaptive base flow and leak compensation
US9144658B2 (en) 2012-04-30 2015-09-29 Covidien Lp Minimizing imposed expiratory resistance of mechanical ventilator by optimizing exhalation valve control
USD731049S1 (en) 2013-03-05 2015-06-02 Covidien Lp EVQ housing of an exhalation module
USD701601S1 (en) 2013-03-08 2014-03-25 Covidien Lp Condensate vial of an exhalation module
USD731048S1 (en) 2013-03-08 2015-06-02 Covidien Lp EVQ diaphragm of an exhalation module
USD744095S1 (en) 2013-03-08 2015-11-24 Covidien Lp Exhalation module EVQ internal flow sensor
USD692556S1 (en) 2013-03-08 2013-10-29 Covidien Lp Expiratory filter body of an exhalation module
USD736905S1 (en) 2013-03-08 2015-08-18 Covidien Lp Exhalation module EVQ housing
USD731065S1 (en) 2013-03-08 2015-06-02 Covidien Lp EVQ pressure sensor filter of an exhalation module
USD693001S1 (en) 2013-03-08 2013-11-05 Covidien Lp Neonate expiratory filter assembly of an exhalation module
US9950135B2 (en) 2013-03-15 2018-04-24 Covidien Lp Maintaining an exhalation valve sensor assembly
USD775345S1 (en) 2015-04-10 2016-12-27 Covidien Lp Ventilator console
CN105854141B (en) * 2016-05-05 2018-07-03 湖南明康中锦医疗科技发展有限公司 A kind of respiratory triggering conversion method and device
US11896767B2 (en) 2020-03-20 2024-02-13 Covidien Lp Model-driven system integration in medical ventilators
CN111921048B (en) * 2020-08-03 2022-06-14 暨南大学 Device and method for external calibration of breathing machine
CN117180574B (en) * 2023-11-07 2024-01-23 中国测试技术研究院辐射研究所 Respirator detection device and measurement method for plateau region

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5520192A (en) * 1991-12-23 1996-05-28 Imperial College Of Science, Technology And Medicine Apparatus for the monitoring and control of respiration
US5522397A (en) * 1993-03-10 1996-06-04 Vermaak; Jan C. Method of and apparatus for monitoring lung function

Family Cites Families (142)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US29778A (en) * 1860-08-28 Appaeatus foe steeet oaes
US1793226A (en) * 1926-04-02 1931-02-17 American Radiator Co Motor-operated device
US2536691A (en) * 1943-03-25 1951-01-02 Alco Valve Co Three-way motor operated valve
US2503563A (en) * 1944-09-30 1950-04-11 Gen Controls Co Valve operator
GB623059A (en) * 1946-11-06 1949-05-11 Henry Rex Marrett Improvements in or relating to apparatus for the administration of inhalent gas mixtures
US2770232A (en) * 1954-05-26 1956-11-13 Smith Welding Equipment Corp Respirator system
US2770231A (en) * 1954-08-18 1956-11-13 Smith Welding Equipment Corp Respirator system
US2880719A (en) * 1955-01-31 1959-04-07 Air Shields Lung ventilators and timing devices therefor
US2892348A (en) * 1955-08-03 1959-06-30 Jr Regner A Ekstrom Flowmeter for fluids
US2904035A (en) * 1957-01-29 1959-09-15 Air Shields Control apparatus for lung ventilators
US3043302A (en) * 1958-05-08 1962-07-10 Oxy Gear Inc Flow control unit for portable inhalators
US3007490A (en) * 1958-06-26 1961-11-07 Allis Chalmers Mfg Co Rotary valve control
US3015963A (en) * 1959-04-20 1962-01-09 A W Cash Valve Mfg Corp Valve mechanism
US3306570A (en) * 1963-10-07 1967-02-28 R D Cooksley Mfg Company Valves and valve structure
US3351057A (en) * 1964-05-28 1967-11-07 Foregger Company Inc Patient safeguarding anesthesia apparatus
US3374410A (en) * 1965-01-06 1968-03-19 Ibm Stepping motor positioning system including acceleration and deceleration control
US3386458A (en) * 1965-06-18 1968-06-04 Air Force Usa Internally actuated combined oxygen pressure regulator and oxygenair dilution valves for respiratory apparatus
US3416054A (en) * 1966-05-10 1968-12-10 Hughes Aircraft Co Motor control apparatus including sequential interval generating means for alternately enabling motor rotation in forward and reverse directions
US3403556A (en) * 1966-07-13 1968-10-01 Automatic Sprinkler Corp Flow measuring device
US3488030A (en) * 1966-08-17 1970-01-06 Halliburton Co Electrical motor operated valve
US3450382A (en) * 1967-01-26 1969-06-17 Master Swaging & Mfg Co Actuator apparatus
US3509895A (en) * 1967-07-20 1970-05-05 Bendix Corp Oxygen regulator
CA902167A (en) * 1967-09-22 1972-06-06 Fairchild Camera And Instrument Corporation Stepper motor control system
DE1922998B2 (en) * 1968-05-16 1971-10-28 CIRCUIT ARRANGEMENT FOR CONTROL OF A STEPPER MOTOR
US3675633A (en) * 1969-01-20 1972-07-11 Nissan Motor Air-pollution preventive system for motor vehicles
US3569813A (en) * 1969-06-09 1971-03-09 Ibm Program controlled positioning device utilizing a stepping motor
US3727627A (en) * 1970-07-15 1973-04-17 H Pohndorf Apparatus for mixing gases
US3813592A (en) * 1971-08-12 1974-05-28 Honeywell Inf Systems Stepping motor acceleration and deceleration control
US3906792A (en) * 1972-03-23 1975-09-23 Sperry Rand Corp Variable throat venturi airspeed sensor
US3795145A (en) * 1972-03-23 1974-03-05 Sperry Rand Corp Variable throat venturi airspeed sensor
US3759099A (en) * 1972-04-03 1973-09-18 Gregor R Mc Flowmeter
US4036221A (en) * 1972-05-01 1977-07-19 Sutter Hospitals Medical Research Foundation Respirator
US3842828A (en) * 1972-09-08 1974-10-22 Bird F M Pediatric ventilator
DE2250174A1 (en) * 1972-10-13 1974-04-18 Draegerwerk Ag GAS MIXING DEVICE FOR COMPRESSED GASES, IN PARTICULAR FOR BREATHING AND MEDICAL DEVICES
US3820539A (en) * 1972-10-19 1974-06-28 Veriflo Corp Ventilator with compliance isolation switch
US3904174A (en) * 1972-10-25 1975-09-09 Tomlinson Ind Inc Web tip seat cup
US3840006A (en) * 1973-04-26 1974-10-08 Department Of Health Education Respirator
US3839662A (en) * 1973-05-08 1974-10-01 Telemecanique Electrique Motorized valve control
US4153021A (en) * 1973-06-04 1979-05-08 Nippon Soken, Inc. Air-fuel mixture ratio correcting system for carburetor
CH568756A5 (en) * 1973-09-07 1975-11-14 Hoffmann La Roche
US3910112A (en) * 1974-05-17 1975-10-07 Southwest Res Inst Flow meter
US3964310A (en) * 1974-05-17 1976-06-22 Dart Industries Inc. Linear response flow meter
USRE29778E (en) 1974-06-07 1978-09-26 Bio-Med Devices, Inc. Pediatric respirator
US3968416A (en) * 1974-07-01 1976-07-06 The Superior Electric Company Motor control for a stepping motor
US3985131A (en) * 1974-11-20 1976-10-12 Searle Cardio-Pulmonary Systems Inc. Infant and pediatric ventilator
JPS51138228A (en) * 1975-05-26 1976-11-29 Nissan Motor Co Ltd Exhaust circulation device
US4024447A (en) * 1975-06-25 1977-05-17 Computer Transceiver Systems, Inc. Stepping motor driving apparatus
JPS5219818A (en) * 1975-08-08 1977-02-15 Hitachi Ltd Mixed gas suppiying device for internal combustion engine
US4006634A (en) * 1975-09-17 1977-02-08 National Semiconductor Corporation Flow meter
JPS5240719A (en) * 1975-09-26 1977-03-29 Hitachi Ltd Motor driving system
DE2558935C3 (en) 1975-12-29 1978-09-21 Siemens Ag, 1000 Berlin Und 8000 Muenchen Flow meter
US4087732A (en) * 1976-05-21 1978-05-02 Pritchard Eric K Digital stepping motor device circuit
US4081736A (en) * 1976-07-09 1978-03-28 The Superior Electric Company Open loop motor stabilization method and circuit
US4126818A (en) * 1976-07-27 1978-11-21 Taylor William W Hybrid stepping motor unit
US4083245A (en) * 1977-03-21 1978-04-11 Research Development Corporation Variable orifice gas flow sensing head
US4114601A (en) * 1976-08-09 1978-09-19 Micro Tec Instrumentation, Inc. Medical and surgical implement detection system
GB1579130A (en) * 1976-08-16 1980-11-12 Secretary Industry Brit Flowrate meters
US4121578A (en) * 1976-10-04 1978-10-24 The Bendix Corporation Physiological responsive control for an oxygen regulator
US4126821A (en) * 1976-10-13 1978-11-21 Dana Corporation Stepping motor control circuit
GB1590581A (en) * 1976-10-14 1981-06-03 Hawker Siddeley Dynamics Eng Electro-hydraulic systems
US4323064A (en) * 1976-10-26 1982-04-06 Puritan-Bennett Corporation Volume ventilator
FR2368942A1 (en) * 1976-10-29 1978-05-26 Arion Henri Gilbert ARTIFICIAL RESPIRATOR DEVICE FOR OPERATION AND RESUSCITATION
JPS5824626B2 (en) * 1976-12-14 1983-05-23 トヨタ自動車株式会社 Exhaust gas recirculation control valve device for internal combustion engines
US4177830A (en) * 1976-12-21 1979-12-11 Bourns, Inc. Valve assembly permitting independent peak flow and decay rate control of periodic gas flows
US4107594A (en) * 1977-01-24 1978-08-15 Teletype Corporation Step motor velocity control
IT1072173B (en) * 1977-02-07 1985-04-10 Weber Edoardo Spa Fabbrica Ita SYSTEM SUITABLE FOR CORRECTING THE TITLE OF THE MIXTURE DELIVERED BY INTEGRATED COMBUSTION ENGINE CARBURETORS
GB1583273A (en) * 1977-05-06 1981-01-21 Medishield Corp Ltd Lung ventilators
NL7707259A (en) * 1977-06-30 1979-01-03 Philips Nv RESPIRATOR.
US4119902A (en) * 1977-07-08 1978-10-10 Mesur-Matic Electronics Corp. Acceleration/deceleration control circuit for a stepping motor
US4176687A (en) * 1977-08-25 1979-12-04 Cla-Val Co. Hollow spool valve
IT1109806B (en) * 1978-01-13 1985-12-23 Pirelli PERFECTED FLOWMETER
DE2919192A1 (en) * 1978-05-26 1979-11-29 Sperry Rand Corp FLOW MEASURING DEVICE
US4199132A (en) * 1978-08-17 1980-04-22 The Perkin-Elmer Corporation High-pressure remote-controlled valve
US4333453A (en) * 1978-10-13 1982-06-08 Rodder Jerome A Respirator valve
US4436090A (en) * 1979-01-22 1984-03-13 Darling Phillip H Piston actuated, pilot valve operated breathing regulator
US4256100A (en) * 1979-02-12 1981-03-17 Rule Medical Instruments, Inc. Flow control equipment
US4256101A (en) * 1979-03-05 1981-03-17 Bourns Medical Systems, Inc. Thermistor assist sensing
FR2455765A1 (en) * 1979-05-02 1980-11-28 Intertechnique Sa REGULATOR DEVICE FOR SUPPLYING GAS TO A RECEIVING MEMBER
DE2926747C2 (en) * 1979-07-03 1982-05-19 Drägerwerk AG, 2400 Lübeck Ventilation system with a ventilator controlled by patient values
US4297998A (en) * 1979-10-12 1981-11-03 Tony Christianson Pilot controlled regulator second stage
US4548382A (en) * 1979-10-18 1985-10-22 Otting Machine Company, Inc. Pinch tube valve
US4266573A (en) * 1979-10-19 1981-05-12 Airco, Inc. Anesthesia machine having proportion limiting control system
US4304136A (en) * 1980-02-01 1981-12-08 Transamerica Delaval Inc. Electrical transducer responsive to fluid flow
US4368646A (en) * 1980-03-18 1983-01-18 Irion & Vosseler, Zahlerfabrik Flow meter for liquid or gaseous media
US4328823A (en) * 1980-05-14 1982-05-11 N.A.D. Inc. Oxygen flow ratio controller for anesthesia apparatus
SE434799B (en) * 1980-06-18 1984-08-20 Gambro Engstrom Ab SET AND DEVICE FOR CONTROL OF A LUNG FAN
US4433685A (en) * 1980-09-10 1984-02-28 Figgie International Inc. Pressure demand regulator with automatic shut-off
JPS5758249A (en) 1980-09-24 1982-04-07 Olympus Optical Co Ltd Optical system recording and/or reproducing device
DE3042448A1 (en) * 1980-11-11 1982-06-24 Robert Bosch Gmbh, 7000 Stuttgart QUANTITY METER
US4401116A (en) * 1980-12-04 1983-08-30 Bear Medical Systems, Inc. Gas flow rate control device for medical ventilator
US4350050A (en) * 1981-02-10 1982-09-21 Deere & Company Flow transducer
US4592349A (en) 1981-08-10 1986-06-03 Bird F M Ventilator having an oscillatory inspiratory phase and method
US4393869A (en) * 1981-06-22 1983-07-19 Canadian Patents & Development Limited Electronically controlled respirator
DE3134065A1 (en) * 1981-08-28 1983-03-10 Mannesmann Rexroth GmbH, 8770 Lohr PRESSURE CONTROL VALVE
US4457304A (en) * 1981-12-04 1984-07-03 Minnesota Mining And Manufacturing Company Self-regulating infant ventilator
US4457339A (en) * 1982-03-03 1984-07-03 Coulter Electronics, Inc. Multiprogrammable pinch valve module
US4448192A (en) * 1982-03-05 1984-05-15 Hewlett Packard Company Medical ventilator device parametrically controlled for patient ventilation
DE3216693A1 (en) * 1982-05-05 1983-11-10 Kienzle Apparate Gmbh, 7730 Villingen-Schwenningen ELECTROPNEUMATIC SERVO VALVE FOR CONTROLLING A VOLUME FLOW OR A PRINT
DE3227229A1 (en) * 1982-07-21 1984-01-26 Robert Bosch Gmbh, 7000 Stuttgart PRESSURE REGULATOR
JPS5985665A (en) 1982-09-13 1984-05-17 イメツド・コ−ポレ−シヨン Apparatus and method of supplying fluid to patient
US4459982A (en) * 1982-09-13 1984-07-17 Bear Medical Systems, Inc. Servo-controlled demand regulator for respiratory ventilator
US4493614A (en) * 1982-10-08 1985-01-15 Lifecare Services, Inc. Pump for a portable ventilator
GB2128883B (en) 1982-10-25 1986-01-08 Normalair Garrett Deep diving apparatus
US4506666A (en) 1982-12-03 1985-03-26 Kircaldie, Randall And Mcnab Method and apparatus for rectifying obstructive apnea
JPS59136550A (en) * 1983-01-27 1984-08-06 Honda Motor Co Ltd Mixture adjusting device for carburettor
GB8305117D0 (en) 1983-02-24 1983-03-30 Penlon Ltd Gas mixing and flow smoothing apparatus
GB8305926D0 (en) * 1983-03-03 1983-04-07 Fluid Devices Ltd Fluid flow sensors
US4606340A (en) 1983-07-14 1986-08-19 Figgie International Inc. Combined pressure compensating exhalation and anti-suffocation valve
DE8322570U1 (en) 1983-08-05 1985-01-17 Robert Bosch Gmbh, 7000 Stuttgart PRESSURE REGULATOR
JPS6099268A (en) 1983-11-04 1985-06-03 シャープ株式会社 Constant flow control system
US4699137A (en) 1983-11-25 1987-10-13 The Boc Group Exhalation valve
US4561408A (en) 1984-01-23 1985-12-31 Borg-Warner Corporation Motorized flow control valve
US4611591A (en) 1984-07-10 1986-09-16 Sharp Kabushiki Kaisha Expiration valve control for automatic respirator
US4619139A (en) 1984-07-23 1986-10-28 Universal Flow Monitors, Inc. Flow meter with displaceable flow rate indicator
GB8424052D0 (en) 1984-09-22 1984-10-31 Cestradent Ltd Controlling gaseous anaesthetic
US4604902A (en) 1984-10-24 1986-08-12 Geoscience Ltd Means and techniques useful in mass flowmeters for multiphase flows
US4602653A (en) 1984-11-01 1986-07-29 Bear Medical Systems, Inc. Electronically-controlled gas blending system
US4527557A (en) * 1984-11-01 1985-07-09 Bear Medical Systems, Inc. Medical ventilator system
US4614122A (en) 1984-12-31 1986-09-30 Emhart Industries, Inc. Fluid flow detector with adaptor
US4617637A (en) 1985-07-09 1986-10-14 Lifecare Services, Inc. Servo control system for a reciprocating piston respirator
US4587967A (en) 1985-07-09 1986-05-13 Lifecare Services, Inc. Oxygen enriched reciprocating piston respirator
US4688433A (en) 1985-07-15 1987-08-25 Pall Corporation Flow sensing device
AU593903B2 (en) 1986-05-07 1990-02-22 Peter Joseph Jackson Pressure regulator
US4702240A (en) 1986-07-22 1987-10-27 Bear Medical Systems, Inc. Demand-responsive gas blending system for medical ventilator
US5072729A (en) 1986-11-04 1991-12-17 Bird Products Corporation Ventilator exhalation valve
GB8704104D0 (en) 1987-02-21 1987-03-25 Manitoba University Of Respiratory system load apparatus
US4790194A (en) 1987-05-01 1988-12-13 Westinghouse Electric Corp. Flow measurement device
US4838257A (en) 1987-07-17 1989-06-13 Hatch Guy M Ventilator
US4840457A (en) 1987-12-17 1989-06-20 General Electric Company Angled strut diaphragm spring
US4854574A (en) 1988-03-15 1989-08-08 501 Healthscan, Inc. Inspirator muscle trainer
US4898174A (en) 1988-05-03 1990-02-06 Life Support Products, Inc. Automatic ventilator
US4957107A (en) 1988-05-10 1990-09-18 Sipin Anatole J Gas delivery means
US4993269A (en) 1988-12-16 1991-02-19 Bird Products Corporation Variable orifice flow sensing apparatus
US5148802B1 (en) 1989-09-22 1997-08-12 Respironics Inc Method and apparatus for maintaining airway patency to treat sleep apnea and other disorders
US5239995A (en) 1989-09-22 1993-08-31 Respironics, Inc. Sleep apnea treatment apparatus
US4966193A (en) 1990-01-30 1990-10-30 Allied-Signal Inc. Timing control for a dual poppet valve
US5127400A (en) 1990-03-23 1992-07-07 Bird Products Corp. Ventilator exhalation valve
US5159924A (en) 1990-10-03 1992-11-03 Cegielski Michael J Method and apparatus for selectively mixing gases
US5014694A (en) 1990-10-15 1991-05-14 Bird Products Corporation Ambient pressure air/oxygen blender
US5099635A (en) 1990-12-04 1992-03-31 J. I. Case Company Drive system for a cotton harvester
US5197895A (en) 1991-05-10 1993-03-30 Bicore Monitoring Systems Disposable electro-fluidic connector with data storage
US5315990A (en) 1991-12-30 1994-05-31 Mondry Adolph J Method for delivering incremental doses of oxygen for maximizing blood oxygen saturation levels

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5520192A (en) * 1991-12-23 1996-05-28 Imperial College Of Science, Technology And Medicine Apparatus for the monitoring and control of respiration
US5522397A (en) * 1993-03-10 1996-06-04 Vermaak; Jan C. Method of and apparatus for monitoring lung function

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012512686A (en) * 2008-12-19 2012-06-07 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ System and method for treating lung disease using positive airway pressure support
WO2011079752A1 (en) * 2009-12-31 2011-07-07 北京谊安医疗系统股份有限公司 Method, device and system for detecting medical equipment
CN111504387A (en) * 2020-05-19 2020-08-07 南京舒普医疗科技有限公司 Breathing machine calibration equipment and breathing machine calibration system

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