WO2001010375A3 - Inhibition of action potentials - Google Patents

Inhibition of action potentials Download PDF

Info

Publication number
WO2001010375A3
WO2001010375A3 PCT/IL2000/000467 IL0000467W WO0110375A3 WO 2001010375 A3 WO2001010375 A3 WO 2001010375A3 IL 0000467 W IL0000467 W IL 0000467W WO 0110375 A3 WO0110375 A3 WO 0110375A3
Authority
WO
WIPO (PCT)
Prior art keywords
nervous tissue
inhibition
action potentials
action potential
electrical energy
Prior art date
Application number
PCT/IL2000/000467
Other languages
French (fr)
Other versions
WO2001010375A2 (en
Inventor
Bella Felsen
Nissim Darvish
Daniel Goldenholz
Original Assignee
Impulse Dynamics Nv
Bella Felsen
Nissim Darvish
Daniel Goldenholz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Impulse Dynamics Nv, Bella Felsen, Nissim Darvish, Daniel Goldenholz filed Critical Impulse Dynamics Nv
Priority to AU64654/00A priority Critical patent/AU6465400A/en
Publication of WO2001010375A2 publication Critical patent/WO2001010375A2/en
Publication of WO2001010375A3 publication Critical patent/WO2001010375A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36071—Pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36003—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of motor muscles, e.g. for walking assistance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3601—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of respiratory organs

Abstract

Apparatus (20) for modifying the electrical behavior of nervous tissue (30) in a human subject is provided. At least one inhibiting electrode (22) is placed in a vicinity of the subject's nervous tissue, and a control unit (40) drives the at least one inhibiting electrode to apply electrical energy to the nervous tissue to inhibit propagation therein of an action potential. Preferably, application of the electrical energy substantially does not cause generation of an action potential in at least a portion of the nervous tissue.
PCT/IL2000/000467 1999-08-04 2000-08-03 Inhibition of action potentials WO2001010375A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU64654/00A AU6465400A (en) 1999-08-04 2000-08-03 Inhibition of action potentials

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36812499A 1999-08-04 1999-08-04
US09/368,124 1999-08-04

Publications (2)

Publication Number Publication Date
WO2001010375A2 WO2001010375A2 (en) 2001-02-15
WO2001010375A3 true WO2001010375A3 (en) 2001-08-16

Family

ID=23449949

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2000/000467 WO2001010375A2 (en) 1999-08-04 2000-08-03 Inhibition of action potentials

Country Status (2)

Country Link
AU (1) AU6465400A (en)
WO (1) WO2001010375A2 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8880192B2 (en) 2012-04-02 2014-11-04 Bio Control Medical (B.C.M.) Ltd. Electrode cuffs
US8909355B2 (en) 2004-11-15 2014-12-09 Bio Control Medical (B.C.M.) Ltd. Techniques for nerve stimulation
US9101765B2 (en) 1999-03-05 2015-08-11 Metacure Limited Non-immediate effects of therapy
US9186504B2 (en) 2010-11-15 2015-11-17 Rainbow Medical Ltd Sleep apnea treatment
US9265930B2 (en) 1997-07-16 2016-02-23 Metacure Limited Methods and devices for modifying vascular parameters
US9457186B2 (en) 2010-11-15 2016-10-04 Bluewind Medical Ltd. Bilateral feedback
US9597521B2 (en) 2015-01-21 2017-03-21 Bluewind Medical Ltd. Transmitting coils for neurostimulation
US11951316B2 (en) 2021-12-09 2024-04-09 Bluewind Medical Ltd. Antenna configuration

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR061600A0 (en) 2000-10-10 2000-11-02 D & E Consulting Pty Ltd Method and apparatus for controlling repetitive nervous system malfunction
US6600954B2 (en) 2001-01-25 2003-07-29 Biocontrol Medical Bcm Ltd. Method and apparatus for selective control of nerve fibers
US6907295B2 (en) 2001-08-31 2005-06-14 Biocontrol Medical Ltd. Electrode assembly for nerve control
US6892098B2 (en) 2001-04-26 2005-05-10 Biocontrol Medical Ltd. Nerve stimulation for treating spasticity, tremor, muscle weakness, and other motor disorders
US6684105B2 (en) * 2001-08-31 2004-01-27 Biocontrol Medical, Ltd. Treatment of disorders by unidirectional nerve stimulation
US7904176B2 (en) 2006-09-07 2011-03-08 Bio Control Medical (B.C.M.) Ltd. Techniques for reducing pain associated with nerve stimulation
US20100010603A1 (en) 2008-07-09 2010-01-14 Tamir Ben-David Electrode cuffs
US7551599B2 (en) 2004-03-29 2009-06-23 Corrigent Systems Ltd. Layer-3 network routing with RPR layer-2 visibility
US8116881B2 (en) 2004-06-10 2012-02-14 Bio Control Medical (B.C.M.) Ltd Electrode assembly for nerve control
ATE533403T1 (en) 2005-03-24 2011-12-15 Metacure Ltd WIRELESS CABLES FOR GASTROINTESTINAL APPLICATIONS
US7974202B2 (en) 2005-05-06 2011-07-05 Corrigent Systems, Ltd. Tunnel provisioning with link aggregation
EP1931319A2 (en) 2005-08-09 2008-06-18 Tylerton International Inc. Satiety
US7545740B2 (en) 2006-04-07 2009-06-09 Corrigent Systems Ltd. Two-way link aggregation
US8423130B2 (en) 2008-05-09 2013-04-16 Metacure Limited Optimization of thresholds for eating detection
WO2013111137A2 (en) 2012-01-26 2013-08-01 Rainbow Medical Ltd. Wireless neurqstimulatqrs
WO2014087337A1 (en) 2012-12-06 2014-06-12 Bluewind Medical Ltd. Delivery of implantable neurostimulators
US9370660B2 (en) 2013-03-29 2016-06-21 Rainbow Medical Ltd. Independently-controlled bidirectional nerve stimulation
US10004896B2 (en) 2015-01-21 2018-06-26 Bluewind Medical Ltd. Anchors and implant devices
US9764146B2 (en) 2015-01-21 2017-09-19 Bluewind Medical Ltd. Extracorporeal implant controllers
US9782589B2 (en) 2015-06-10 2017-10-10 Bluewind Medical Ltd. Implantable electrostimulator for improving blood flow
US10105540B2 (en) 2015-11-09 2018-10-23 Bluewind Medical Ltd. Optimization of application of current
US9713707B2 (en) 2015-11-12 2017-07-25 Bluewind Medical Ltd. Inhibition of implant migration
US10124178B2 (en) 2016-11-23 2018-11-13 Bluewind Medical Ltd. Implant and delivery tool therefor
US20180353764A1 (en) 2017-06-13 2018-12-13 Bluewind Medical Ltd. Antenna configuration
US11400299B1 (en) 2021-09-14 2022-08-02 Rainbow Medical Ltd. Flexible antenna for stimulator

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4608985A (en) * 1984-10-11 1986-09-02 Case Western Reserve University Antidromic pulse generating wave form for collision blocking
US5178161A (en) * 1988-09-02 1993-01-12 The Board Of Trustees Of The Leland Stanford Junior University Microelectronic interface
US5330515A (en) * 1992-06-17 1994-07-19 Cyberonics, Inc. Treatment of pain by vagal afferent stimulation
US5702429A (en) * 1996-04-04 1997-12-30 Medtronic, Inc. Neural stimulation techniques with feedback
US5716377A (en) * 1996-04-25 1998-02-10 Medtronic, Inc. Method of treating movement disorders by brain stimulation
US5755750A (en) * 1995-11-13 1998-05-26 University Of Florida Method and apparatus for selectively inhibiting activity in nerve fibers
US5792186A (en) * 1996-04-25 1998-08-11 Medtronic, Inc. Method and apparatus for treating neurodegenerative disorders by electrical brain stimulation
WO1999003533A1 (en) * 1997-07-16 1999-01-28 Impulse Dynamics (Israel) Ltd. Smooth muscle controller

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4784142A (en) 1984-01-09 1988-11-15 Pain Suppression Labs, Inc. Methodology for electronic dental analgesia
US5312321A (en) 1986-11-21 1994-05-17 Holcomb Technology, Inc. Method and apparatus for suppressing neuron action potential firings
US5018525A (en) 1989-11-01 1991-05-28 Kharkovski Medicinsky Institute Device for dental electroanalgesia
US5203326A (en) 1991-12-18 1993-04-20 Telectronics Pacing Systems, Inc. Antiarrhythmia pacer using antiarrhythmia pacing and autonomic nerve stimulation therapy
US5324317A (en) 1992-09-30 1994-06-28 Medserve Group, Inc. Interferential stimulator for applying low frequency alternating current to the body
US5713923A (en) 1996-05-13 1998-02-03 Medtronic, Inc. Techniques for treating epilepsy by brain stimulation and drug infusion

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4608985A (en) * 1984-10-11 1986-09-02 Case Western Reserve University Antidromic pulse generating wave form for collision blocking
US5178161A (en) * 1988-09-02 1993-01-12 The Board Of Trustees Of The Leland Stanford Junior University Microelectronic interface
US5330515A (en) * 1992-06-17 1994-07-19 Cyberonics, Inc. Treatment of pain by vagal afferent stimulation
US5755750A (en) * 1995-11-13 1998-05-26 University Of Florida Method and apparatus for selectively inhibiting activity in nerve fibers
US5702429A (en) * 1996-04-04 1997-12-30 Medtronic, Inc. Neural stimulation techniques with feedback
US5716377A (en) * 1996-04-25 1998-02-10 Medtronic, Inc. Method of treating movement disorders by brain stimulation
US5792186A (en) * 1996-04-25 1998-08-11 Medtronic, Inc. Method and apparatus for treating neurodegenerative disorders by electrical brain stimulation
WO1999003533A1 (en) * 1997-07-16 1999-01-28 Impulse Dynamics (Israel) Ltd. Smooth muscle controller

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9265930B2 (en) 1997-07-16 2016-02-23 Metacure Limited Methods and devices for modifying vascular parameters
US9101765B2 (en) 1999-03-05 2015-08-11 Metacure Limited Non-immediate effects of therapy
US8909355B2 (en) 2004-11-15 2014-12-09 Bio Control Medical (B.C.M.) Ltd. Techniques for nerve stimulation
US9186504B2 (en) 2010-11-15 2015-11-17 Rainbow Medical Ltd Sleep apnea treatment
US9457186B2 (en) 2010-11-15 2016-10-04 Bluewind Medical Ltd. Bilateral feedback
US8880192B2 (en) 2012-04-02 2014-11-04 Bio Control Medical (B.C.M.) Ltd. Electrode cuffs
US9597521B2 (en) 2015-01-21 2017-03-21 Bluewind Medical Ltd. Transmitting coils for neurostimulation
US11951316B2 (en) 2021-12-09 2024-04-09 Bluewind Medical Ltd. Antenna configuration

Also Published As

Publication number Publication date
AU6465400A (en) 2001-03-05
WO2001010375A2 (en) 2001-02-15

Similar Documents

Publication Publication Date Title
WO2001010375A3 (en) Inhibition of action potentials
WO2002034327A3 (en) Method and apparatus to minimize the effects of a cardiac insult
WO2002034330A3 (en) Method and apparatus to minimize the effects of a cardiac insult
GB2269750B (en) Electrical stimulation for treatment of incontinence and other neuro-muscular disorders
CA2235365A1 (en) Apparatus and method for delivering electrical stimulus to tissue
AU3357297A (en) Cardiac output enhanced pacemaker
GB2380414A (en) Stimulation method for the sphenopalatine ganglia,sphenopalatine nerve,or vidian nerve for treatment of medical conditions
AU565851B2 (en) Stimulating penile erection tissue
AU2003295342A1 (en) Medical device comprising a nanoactuator
WO2002003872A3 (en) Application of photochemotherapy for the treatment of cardiac arrhythmias
WO2002026313A3 (en) Method and apparatus employing a scaling exponent for selectively defibrillating a patient
WO2005051479A3 (en) Electrical stimulation system and method for treating tinnitus
WO2001010496A3 (en) Method and apparatus for waveform output
AU2001289037A1 (en) Electrical stimulation of tissue for therapeutic and diagnostic purposes
AU6012900A (en) Apparatus and method for treating body tissues with electricity or medicaments
EP1080731A3 (en) Composition and device structure for iontophoresis
AU2002232523A1 (en) Pacing methods and devices for treating cardiac arrhythmias and fibrillation
AU6278199A (en) Ultrasonic device for providing reversible tissue damage to heart muscle
AU4028597A (en) Minimally invasive direct cardiac massage device and method
AU6118799A (en) Incontinence treatment device
ZA928345B (en) Treatment of acne of pseudofolliculitis barbae.
WO2001058518A8 (en) Cardiac control using paired pacing
AUPQ952800A0 (en) Power efficient electrical stimulation
ATE219929T1 (en) SKIN BLEACHING DERMATOLOGICAL AND/OR COSMETIC COMPOSITION
AU2003291815A1 (en) Pacing therapy for extending atrial refractory period

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP