WO2001058266A1 - Therapeutic platelets and methods - Google Patents
Therapeutic platelets and methods Download PDFInfo
- Publication number
- WO2001058266A1 WO2001058266A1 PCT/US2001/004224 US0104224W WO0158266A1 WO 2001058266 A1 WO2001058266 A1 WO 2001058266A1 US 0104224 W US0104224 W US 0104224W WO 0158266 A1 WO0158266 A1 WO 0158266A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- platelets
- trehalose
- freeze
- dried
- composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/19—Platelets; Megacaryocytes
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0205—Chemical aspects
- A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
- A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0205—Chemical aspects
- A01N1/0231—Chemically defined matrices, e.g. alginate gels, for immobilising, holding or storing cells, tissue or organs for preservation purposes; Chemically altering or fixing cells, tissue or organs, e.g. by cross-linking, for preservation purposes
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0278—Physical preservation processes
- A01N1/0284—Temperature processes, i.e. using a designated change in temperature over time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01907169A EP1255439A4 (en) | 2000-02-10 | 2001-02-08 | Therapeutic platelets and methods |
JP2001557391A JP2004502641A (en) | 2000-02-10 | 2001-02-08 | Therapeutic platelets and methods |
AU2001234978A AU2001234978A1 (en) | 2000-02-10 | 2001-02-08 | Therapeutic platelets and methods |
CA002397362A CA2397362A1 (en) | 2000-02-10 | 2001-02-08 | Therapeutic platelets and methods |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50177300A | 2000-02-10 | 2000-02-10 | |
US09/501,773 | 2000-02-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2001058266A1 true WO2001058266A1 (en) | 2001-08-16 |
Family
ID=23994957
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/004224 WO2001058266A1 (en) | 2000-02-10 | 2001-02-08 | Therapeutic platelets and methods |
Country Status (6)
Country | Link |
---|---|
US (5) | US6723497B2 (en) |
EP (1) | EP1255439A4 (en) |
JP (1) | JP2004502641A (en) |
AU (1) | AU2001234978A1 (en) |
CA (1) | CA2397362A1 (en) |
WO (1) | WO2001058266A1 (en) |
Cited By (13)
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---|---|---|---|---|
US6610291B2 (en) | 1999-12-29 | 2003-08-26 | Dade Behring Marburg Gmbh | Ready-to-use ristocetin cofactor test reagent possessing long-term stability |
WO2007038629A2 (en) | 2005-09-26 | 2007-04-05 | Lifecell Corporation | Dry platelet composition |
WO2006020773A3 (en) * | 2004-08-12 | 2007-07-12 | Adlyfe Inc | Methods for preparing freeze-dried platelets, compositions comprising freeze-dried platelets, and methods of use |
US7811558B2 (en) | 2004-08-12 | 2010-10-12 | Cellphire, Inc. | Use of stabilized platelets as hemostatic agent |
CN101957364A (en) * | 2010-09-19 | 2011-01-26 | 李勇 | Preparation method of lyophilization type platelet antigen spectrum cells |
US8097403B2 (en) | 2006-12-14 | 2012-01-17 | Cellphire, Inc. | Freeze-dried platelets, method of making and method of use as a diagnostic agent |
WO2019224709A1 (en) * | 2018-05-22 | 2019-11-28 | Jawaharlal Nehru University | Antibiotic delivery system |
WO2021232015A1 (en) * | 2020-05-15 | 2021-11-18 | Cellphire, Inc. | Platelet derived extracellular vesicles |
EP3886879A4 (en) * | 2018-11-30 | 2022-12-07 | Cellphire Inc. | Platelets as delivery agents |
US11529587B2 (en) | 2019-05-03 | 2022-12-20 | Cellphire, Inc. | Materials and methods for producing blood products |
US11701388B2 (en) | 2019-08-16 | 2023-07-18 | Cellphire, Inc. | Thrombosomes as an antiplatelet agent reversal agent |
US11903971B2 (en) | 2020-02-04 | 2024-02-20 | Cellphire, Inc. | Treatment of von Willebrand disease |
US11965178B2 (en) | 2018-11-30 | 2024-04-23 | Cellphire, Inc. | Platelets loaded with anti-cancer agents |
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EP1255439A4 (en) * | 2000-02-10 | 2007-01-03 | Univ California | Therapeutic platelets and methods |
US20020076445A1 (en) * | 2000-02-10 | 2002-06-20 | Crowe John H. | Eukaryotic cells and method for preserving cells |
US6653062B1 (en) | 2000-07-26 | 2003-11-25 | Wisconsin Alumni Research Foundation | Preservation and storage medium for biological materials |
US20030108972A1 (en) * | 2001-12-06 | 2003-06-12 | Zweig Stephen Eliot | Tethered receptor-ligand reagent and assay |
US7294455B2 (en) * | 2003-05-16 | 2007-11-13 | The University Of North Carolina At Chapel Hill | Fixed-dried platelets cross-linked to protein |
US20070077237A1 (en) * | 2003-10-09 | 2007-04-05 | Udi Damari | Method for freezing, thawing and transplantation of viable cartilage |
US7314755B2 (en) * | 2003-10-15 | 2008-01-01 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Preservation of eukaryotic cells using reversible pore formation |
EP1711214A1 (en) * | 2004-02-02 | 2006-10-18 | Interface Multigrad Technology (IMT) Ltd. | Device for directional cooling of biological matter |
EP1711053A2 (en) * | 2004-02-02 | 2006-10-18 | I.M.T. Interface Multigrad Technology Ltd. | Biological material and methods and solutions for preservation thereof |
US20050191286A1 (en) * | 2004-02-09 | 2005-09-01 | Gandy James B. | Lyophilized platelet rich plasma for the use in wound healing (chronic or acute) and bone or tissue grafts or repair |
CN1333126C (en) * | 2004-04-28 | 2007-08-22 | 王小建 | Method for preparing hemostatic fiber non-woven cloth |
DE602005019998D1 (en) * | 2004-06-07 | 2010-04-29 | Core Dynamics Ltd | PROCESS FOR STERILIZING BIOLOGICAL PREPARATIONS |
US20060004189A1 (en) * | 2004-07-02 | 2006-01-05 | James Gandy | Compositions for treating wounds and processes for their preparation |
US20060142198A1 (en) * | 2004-07-02 | 2006-06-29 | Wound Care Partners Llc | Compositions for treating wounds and processes for their preparation |
EP1778007A1 (en) * | 2004-08-12 | 2007-05-02 | I.M.T. Interface Multigrad Technology Ltd. | Method and apparatus for freezing or thawing of a biological material |
US7718167B2 (en) * | 2004-09-13 | 2010-05-18 | Hynes Richard A | Method for treating wounds exposing the dura using PPP and PRP |
EP1850661A2 (en) * | 2005-02-22 | 2007-11-07 | Interface Multigrad Technology (IMT) Ltd. | Preserved viable cartilage, method for its preservation, and system and devices used therefor |
EP1909565A2 (en) * | 2005-08-03 | 2008-04-16 | Interface Multigrad Technology (IMT) Ltd. | Somatic cells for use in cell therapy |
BRPI0520502A2 (en) * | 2005-08-30 | 2009-06-13 | Mackie J Walker Jr | dehydrated composition usable for mammal therapy, wound healing composition, wound healing method, wound healing, and wound healing method |
US8277837B2 (en) | 2006-01-11 | 2012-10-02 | Entegrion, Inc. | Hemostatic textile |
JP2007197353A (en) * | 2006-01-25 | 2007-08-09 | Univ Of Tsukuba | Liver regeneration promoter |
US8372437B2 (en) | 2006-08-17 | 2013-02-12 | Mimedx Group, Inc. | Placental tissue grafts |
WO2008027917A2 (en) * | 2006-08-28 | 2008-03-06 | The Regents Of The University Of California | Method of freezing platelets that preserves active platelet growth factors |
US8372427B2 (en) | 2007-03-05 | 2013-02-12 | Abbott Cardiovascular Systems Inc. | Therapeutic composition with enhanced endothelium targeting |
US8357403B2 (en) | 2007-09-07 | 2013-01-22 | Mimedx Group, Inc. | Placental tissue grafts |
US20090081785A1 (en) * | 2007-09-24 | 2009-03-26 | Hememics Biotechnologies, Inc. | Desiccated Biologics And Methods Of Preparing The Same |
US20090090022A1 (en) * | 2007-10-09 | 2009-04-09 | Hememics Biotechnologies, Inc. | Desiccation Chamber and Methods for Drying Biological Materials |
US8835104B2 (en) | 2007-12-20 | 2014-09-16 | Fenwal, Inc. | Medium and methods for the storage of platelets |
US20090202978A1 (en) * | 2008-02-13 | 2009-08-13 | Ginadi Shaham | Method and apparatus for freezing of a biological material |
CA2743841C (en) * | 2008-11-13 | 2020-09-01 | Eastern Virginia Medical School | Activation and aggregation of human platelets and formation of platelet gels by nanosecond pulsed electric fields |
US9867782B2 (en) * | 2009-04-09 | 2018-01-16 | Entegrion, Inc. | Spray-dried blood products and methods of making same |
WO2011035062A2 (en) | 2009-09-16 | 2011-03-24 | Velico Medical, Inc. | Spray dried human plasma |
US8407912B2 (en) | 2010-09-16 | 2013-04-02 | Velico Medical, Inc. | Spray dried human plasma |
WO2011103114A1 (en) | 2010-02-17 | 2011-08-25 | Hememics Biotechnologies, Inc. | Preservation solutions for biologics and methods related thereto |
US8802363B2 (en) * | 2010-04-08 | 2014-08-12 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Zeodration method for the preservation of blood platelets |
US8533971B2 (en) | 2010-10-29 | 2013-09-17 | Velico Medical, Inc. | System and method for spray drying a liquid |
US20140083628A1 (en) | 2012-09-27 | 2014-03-27 | Velico Medical, Inc. | Spray drier assembly for automated spray drying |
EP2694131B1 (en) | 2011-04-07 | 2019-08-28 | Fenwal, Inc. | Automated methods and systems for providing platelet concentrates with reduced residual plasma volumes and storage media for such platelet concentrates |
US20150250822A1 (en) * | 2012-10-04 | 2015-09-10 | Genesys Research Institute | Platelet compositions and uses thereof |
US9561184B2 (en) | 2014-09-19 | 2017-02-07 | Velico Medical, Inc. | Methods and systems for multi-stage drying of plasma |
US10815456B2 (en) | 2016-10-04 | 2020-10-27 | Transwell Biotech Co., Ltd. | Composition, kit and method for cryopreserving cells |
EP3681518A4 (en) * | 2017-09-13 | 2021-06-23 | Cellphire Inc. | Canine blood platelet preparations |
CA3078625C (en) | 2017-10-09 | 2023-01-17 | Terumo Bct Biotechnologies, Llc | Lyophilization container and method of using same |
WO2020185909A2 (en) | 2019-03-14 | 2020-09-17 | Terumo Bct Biotechnologies, Llc | Lyophilization loading tray assembly and system |
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US11841189B1 (en) | 2022-09-15 | 2023-12-12 | Velico Medical, Inc. | Disposable for a spray drying system |
Citations (1)
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US5651966A (en) * | 1992-05-29 | 1997-07-29 | The University Of North Carolina At Chapel Hill | Pharmaceutically acceptable fixed-dried human blood platelets |
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-
2001
- 2001-02-08 EP EP01907169A patent/EP1255439A4/en active Pending
- 2001-02-08 CA CA002397362A patent/CA2397362A1/en not_active Abandoned
- 2001-02-08 JP JP2001557391A patent/JP2004502641A/en not_active Withdrawn
- 2001-02-08 AU AU2001234978A patent/AU2001234978A1/en not_active Abandoned
- 2001-02-08 WO PCT/US2001/004224 patent/WO2001058266A1/en not_active Application Discontinuation
- 2001-04-05 US US09/828,627 patent/US6723497B2/en not_active Expired - Fee Related
- 2001-08-23 US US09/938,408 patent/US20020009500A1/en not_active Abandoned
-
2004
- 2004-03-16 US US10/802,099 patent/US20040175374A1/en not_active Abandoned
- 2004-03-24 US US10/807,614 patent/US20040265293A1/en not_active Abandoned
-
2005
- 2005-12-22 US US11/317,411 patent/US20060134084A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5651966A (en) * | 1992-05-29 | 1997-07-29 | The University Of North Carolina At Chapel Hill | Pharmaceutically acceptable fixed-dried human blood platelets |
Non-Patent Citations (1)
Title |
---|
See also references of EP1255439A4 * |
Cited By (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6610291B2 (en) | 1999-12-29 | 2003-08-26 | Dade Behring Marburg Gmbh | Ready-to-use ristocetin cofactor test reagent possessing long-term stability |
WO2006020773A3 (en) * | 2004-08-12 | 2007-07-12 | Adlyfe Inc | Methods for preparing freeze-dried platelets, compositions comprising freeze-dried platelets, and methods of use |
AU2005272821B2 (en) * | 2004-08-12 | 2010-09-09 | Cellphire, Inc | Methods for preparing freeze-dried platelets, compositions comprising freeze-dried platelets, and methods of use |
US7811558B2 (en) | 2004-08-12 | 2010-10-12 | Cellphire, Inc. | Use of stabilized platelets as hemostatic agent |
US8486617B2 (en) | 2004-08-12 | 2013-07-16 | Cellphirc, Inc | Methods for preparing freeze-dried platelets, compositions comprising freeze-dried platelets, and methods of use |
WO2007038629A2 (en) | 2005-09-26 | 2007-04-05 | Lifecell Corporation | Dry platelet composition |
EP1929289A2 (en) * | 2005-09-26 | 2008-06-11 | Lifecell Corporation | Dry platelet composition |
EP1929289B1 (en) * | 2005-09-26 | 2018-02-21 | Lifecell Corporation | Dry platelet composition |
US8097403B2 (en) | 2006-12-14 | 2012-01-17 | Cellphire, Inc. | Freeze-dried platelets, method of making and method of use as a diagnostic agent |
CN101957364A (en) * | 2010-09-19 | 2011-01-26 | 李勇 | Preparation method of lyophilization type platelet antigen spectrum cells |
WO2019224709A1 (en) * | 2018-05-22 | 2019-11-28 | Jawaharlal Nehru University | Antibiotic delivery system |
EP3886879A4 (en) * | 2018-11-30 | 2022-12-07 | Cellphire Inc. | Platelets as delivery agents |
US11767511B2 (en) | 2018-11-30 | 2023-09-26 | Cellphire, Inc. | Platelets as delivery agents |
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Also Published As
Publication number | Publication date |
---|---|
US20010019819A1 (en) | 2001-09-06 |
AU2001234978A1 (en) | 2001-08-20 |
US20040265293A1 (en) | 2004-12-30 |
JP2004502641A (en) | 2004-01-29 |
US6723497B2 (en) | 2004-04-20 |
US20020009500A1 (en) | 2002-01-24 |
EP1255439A4 (en) | 2007-01-03 |
US20040175374A1 (en) | 2004-09-09 |
EP1255439A1 (en) | 2002-11-13 |
US20060134084A1 (en) | 2006-06-22 |
CA2397362A1 (en) | 2001-08-16 |
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