WO2001080826A3 - Taste masking coating composition - Google Patents

Taste masking coating composition Download PDF

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Publication number
WO2001080826A3
WO2001080826A3 PCT/US2001/012709 US0112709W WO0180826A3 WO 2001080826 A3 WO2001080826 A3 WO 2001080826A3 US 0112709 W US0112709 W US 0112709W WO 0180826 A3 WO0180826 A3 WO 0180826A3
Authority
WO
WIPO (PCT)
Prior art keywords
coating composition
taste masking
masking coating
masks
medicine
Prior art date
Application number
PCT/US2001/012709
Other languages
French (fr)
Other versions
WO2001080826A2 (en
Inventor
Michael Corbo
Jatin Desai
Mahesh Patell
Ronald Warrick
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Priority to DE60128215T priority Critical patent/DE60128215T2/en
Priority to AU2001257107A priority patent/AU2001257107A1/en
Priority to EP01930585A priority patent/EP1276470B1/en
Priority to DK01930585T priority patent/DK1276470T3/en
Publication of WO2001080826A2 publication Critical patent/WO2001080826A2/en
Publication of WO2001080826A3 publication Critical patent/WO2001080826A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose

Abstract

There is provided a coating composition that masks the undesirable taste of a pharmaceutically active ingredient, i.e. drug or medicine, that is taken orally. The coating composition has a dimethylaminoethyl methacrylate and neutral methacrylic acid ester, a cellulose ester polymer, and an alkaline modifier.
PCT/US2001/012709 2000-04-20 2001-04-18 Taste masking coating composition WO2001080826A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DE60128215T DE60128215T2 (en) 2000-04-20 2001-04-18 COATING COMPOSITION FOR TASTE MASKING
AU2001257107A AU2001257107A1 (en) 2000-04-20 2001-04-18 Taste masking coating composition
EP01930585A EP1276470B1 (en) 2000-04-20 2001-04-18 Taste masking coating composition
DK01930585T DK1276470T3 (en) 2000-04-20 2001-04-18 Flavor-crushing coating composition

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55792400A 2000-04-20 2000-04-20
US09/557,924 2000-04-20

Publications (2)

Publication Number Publication Date
WO2001080826A2 WO2001080826A2 (en) 2001-11-01
WO2001080826A3 true WO2001080826A3 (en) 2002-03-21

Family

ID=24227421

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/012709 WO2001080826A2 (en) 2000-04-20 2001-04-18 Taste masking coating composition

Country Status (9)

Country Link
US (1) US6663893B2 (en)
EP (1) EP1276470B1 (en)
AT (1) ATE361061T1 (en)
AU (1) AU2001257107A1 (en)
DE (1) DE60128215T2 (en)
DK (1) DK1276470T3 (en)
ES (1) ES2284643T3 (en)
PT (1) PT1276470E (en)
WO (1) WO2001080826A2 (en)

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US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
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EA032013B1 (en) * 2013-10-31 2019-03-29 Сайма Лэбс Инк. Immediate release abuse-deterrent granulated dosage forms
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CN106389339B (en) * 2015-08-12 2020-08-04 北京科信必成医药科技发展有限公司 Aspirin taste-masking granule capable of being swallowed without water and preparation method thereof
CN105935445B (en) * 2016-03-28 2019-02-01 赤峰赛林泰药业有限公司 Pharmaceutical composition and preparation method thereof containing 2- (- 4- isobutyl phenenyl) propionic acid dextrogyre
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WO2001003698A1 (en) * 1999-07-09 2001-01-18 Ortho-Mcneil Pharmaceutical, Inc. Taste masked pharmaceutical liquid formulations

Also Published As

Publication number Publication date
PT1276470E (en) 2007-08-13
AU2001257107A1 (en) 2001-11-07
DE60128215T2 (en) 2008-01-10
US6663893B2 (en) 2003-12-16
DE60128215D1 (en) 2007-06-14
DK1276470T3 (en) 2007-06-18
WO2001080826A2 (en) 2001-11-01
EP1276470B1 (en) 2007-05-02
EP1276470A2 (en) 2003-01-22
ATE361061T1 (en) 2007-05-15
US20020197317A1 (en) 2002-12-26
ES2284643T3 (en) 2007-11-16

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