WO2001081892A3 - Laser capture microdissection (lcm) extraction device and device carrier and method for post-lcm fluid processing - Google Patents

Laser capture microdissection (lcm) extraction device and device carrier and method for post-lcm fluid processing Download PDF

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Publication number
WO2001081892A3
WO2001081892A3 PCT/US2001/013796 US0113796W WO0181892A3 WO 2001081892 A3 WO2001081892 A3 WO 2001081892A3 US 0113796 W US0113796 W US 0113796W WO 0181892 A3 WO0181892 A3 WO 0181892A3
Authority
WO
WIPO (PCT)
Prior art keywords
lcm
post
fluid processing
extraction
transfer film
Prior art date
Application number
PCT/US2001/013796
Other languages
French (fr)
Other versions
WO2001081892A2 (en
Inventor
Thomas M Baer
Robert H Reamey
Keith E Moravick
David F Head
Bruce J Richardson
Derrick A Richardson
Original Assignee
Arcturus Eng Inc
Thomas M Baer
Robert H Reamey
Keith E Moravick
David F Head
Bruce J Richardson
Derrick A Richardson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arcturus Eng Inc, Thomas M Baer, Robert H Reamey, Keith E Moravick, David F Head, Bruce J Richardson, Derrick A Richardson filed Critical Arcturus Eng Inc
Priority to EP01932737.8A priority Critical patent/EP1279020B1/en
Priority to AU2001259241A priority patent/AU2001259241A1/en
Publication of WO2001081892A2 publication Critical patent/WO2001081892A2/en
Publication of WO2001081892A3 publication Critical patent/WO2001081892A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G01N2001/2833—Collecting samples on a sticky, tacky, adhesive surface
    • G01N2001/284—Collecting samples on a sticky, tacky, adhesive surface using local activation of adhesive, i.e. Laser Capture Microdissection
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction

Abstract

The present invention generally discloses an extraction system (10) that provides a locale for fluid processing and extraction on a post-microcapture transfer film (28). The extraction system includes a transfer film carrier (12) and an extraction device (14) forming a reservoir. The extraction system (10) selectively excludes regions (90) of the transfer film (28) from the reservoir to advantageously reduce contamination due to matter adhered to the transfer film by non-specific transfer.
PCT/US2001/013796 2000-04-26 2001-04-26 Laser capture microdissection (lcm) extraction device and device carrier and method for post-lcm fluid processing WO2001081892A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP01932737.8A EP1279020B1 (en) 2000-04-26 2001-04-26 Laser capture microdissection (lcm) extraction device and device carrier and method for post-lcm fluid processing
AU2001259241A AU2001259241A1 (en) 2000-04-26 2001-04-26 Laser capture microdissection (lcm) extraction device and device carrier and method for post-lcm fluid processing

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19993100P 2000-04-26 2000-04-26
US60/199,931 2000-04-26

Publications (2)

Publication Number Publication Date
WO2001081892A2 WO2001081892A2 (en) 2001-11-01
WO2001081892A3 true WO2001081892A3 (en) 2002-06-06

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/013796 WO2001081892A2 (en) 2000-04-26 2001-04-26 Laser capture microdissection (lcm) extraction device and device carrier and method for post-lcm fluid processing

Country Status (4)

Country Link
US (3) US7776273B2 (en)
EP (1) EP1279020B1 (en)
AU (1) AU2001259241A1 (en)
WO (1) WO2001081892A2 (en)

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AU2001259241A1 (en) * 2000-04-26 2001-11-07 Arcturus Engineering, Inc. Laser capture microdissection (lcm) extraction device and device carrier and method for post-lcm fluid processing
US8722357B2 (en) * 2001-11-05 2014-05-13 Life Technologies Corporation Automated microdissection instrument
US10156501B2 (en) 2001-11-05 2018-12-18 Life Technologies Corporation Automated microdissection instrument for determining a location of a laser beam projection on a worksurface area
TWI236500B (en) * 2002-10-18 2005-07-21 Ind Tech Res Inst Device and method for capturing biological tissues
EP1787101B1 (en) * 2004-09-09 2014-11-12 Life Technologies Corporation Laser microdissection apparatus and method
US8000773B2 (en) * 2004-11-09 2011-08-16 Spectrum Dynamics Llc Radioimaging
US20080134806A1 (en) * 2006-12-06 2008-06-12 Agamatrix, Inc. Container system for dispensing a liquid
US20090225309A1 (en) * 2008-03-04 2009-09-10 Demou Zoe N Time-lapse analysis chamber for laser capture microdissection applications
IT1391385B1 (en) * 2008-10-14 2011-12-13 Univ Bologna Alma Mater SUPERCONDUCTIVE FAULT CURRENT LIMITER.
DE102011076238A1 (en) * 2011-05-20 2012-11-22 Siemens Ag Arrangement and method for optical analysis and specific isolation of biological samples
US10429279B2 (en) 2013-07-28 2019-10-01 Xmd, Llc Devices and cartridges for extracting bio-sample regions and molecules of interest
WO2017027620A1 (en) 2015-08-10 2017-02-16 Life Technologies Corporation Devices and methods for laser capture microdissection
US10324008B2 (en) * 2015-12-22 2019-06-18 George Mason Research Foundation Compositions and methods for laser capture microdissection
US20220019069A1 (en) 2019-01-09 2022-01-20 Google Llc Augmented Reality Laser Capture Microdissection Machine
WO2023170171A1 (en) * 2022-03-10 2023-09-14 Molecular Machines & Industries Gmbh Biological sample transfer and rearrangement method

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Also Published As

Publication number Publication date
US20160003717A1 (en) 2016-01-07
EP1279020A2 (en) 2003-01-29
US9103757B2 (en) 2015-08-11
AU2001259241A1 (en) 2001-11-07
US20020001837A1 (en) 2002-01-03
EP1279020B1 (en) 2016-03-16
US7776273B2 (en) 2010-08-17
WO2001081892A2 (en) 2001-11-01
US20110059548A1 (en) 2011-03-10

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