WO2001087410A3 - Cardiac stimulation devices and methods for measuring impedances associated with the left side of the heart - Google Patents

Cardiac stimulation devices and methods for measuring impedances associated with the left side of the heart Download PDF

Info

Publication number
WO2001087410A3
WO2001087410A3 PCT/US2001/015520 US0115520W WO0187410A3 WO 2001087410 A3 WO2001087410 A3 WO 2001087410A3 US 0115520 W US0115520 W US 0115520W WO 0187410 A3 WO0187410 A3 WO 0187410A3
Authority
WO
WIPO (PCT)
Prior art keywords
heart
pacing
methods
measuring
location
Prior art date
Application number
PCT/US2001/015520
Other languages
French (fr)
Other versions
WO2001087410A2 (en
Inventor
Kerry Bradley
Gene A Bornzin
Euljoon Park
Mark W Kroll
Original Assignee
Pacesetter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pacesetter Inc filed Critical Pacesetter Inc
Priority to AU2001263108A priority Critical patent/AU2001263108A1/en
Publication of WO2001087410A2 publication Critical patent/WO2001087410A2/en
Publication of WO2001087410A3 publication Critical patent/WO2001087410A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362Heart stimulators
    • A61N1/365Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/36514Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure
    • A61N1/36521Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure the parameter being derived from measurement of an electrical impedance

Abstract

Methods of and systems for measuring at least one physiological parameter for assessing a patient's cardiac condition based on left heart impedance measurements are described. Various embodiments establish a current flow through a left side of the heart and measure a voltage between a first location on or in the left side of the heart and a second location within the human body while establishing the current flow. The inventive techniques and systems can be used for, among other things, measuring progression or regression of myocardial failure, dilation, or hypertrophy, pulmonary congestion, myocardial contractility, or ejection fraction. The measured voltage, related to left heart impedance, can be used to monitor patient condition for diagnostic purposes or to adapt pacing or defibrillation therapy. Therapy adaptation can include controlling pacing modes, pacing rates, or interchamber pacing delays, for example.
PCT/US2001/015520 2000-05-15 2001-05-14 Cardiac stimulation devices and methods for measuring impedances associated with the left side of the heart WO2001087410A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001263108A AU2001263108A1 (en) 2000-05-15 2001-05-14 Cardiac stimulation devices and methods for measuring impedances associated withthe left side of the heart

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20431000P 2000-05-15 2000-05-15
US60/204,310 2000-05-15

Publications (2)

Publication Number Publication Date
WO2001087410A2 WO2001087410A2 (en) 2001-11-22
WO2001087410A3 true WO2001087410A3 (en) 2002-03-21

Family

ID=22757394

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/015520 WO2001087410A2 (en) 2000-05-15 2001-05-14 Cardiac stimulation devices and methods for measuring impedances associated with the left side of the heart

Country Status (3)

Country Link
US (1) US20020002389A1 (en)
AU (1) AU2001263108A1 (en)
WO (1) WO2001087410A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8010196B1 (en) 2006-03-31 2011-08-30 Pacesetter, Inc. Tissue characterization using intracardiac impedances with an implantable lead system
US9066662B2 (en) 2007-04-04 2015-06-30 Pacesetter, Inc. System and method for estimating cardiac pressure based on cardiac electrical conduction delays using an implantable medical device
US9113789B2 (en) 2007-04-04 2015-08-25 Pacesetter, Inc. System and method for estimating electrical conduction delays from immittance values measured using an implantable medical device

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7158830B2 (en) * 1998-05-08 2007-01-02 Cardiac Pacemakers, Inc. Method and apparatus for optimizing stroke volume during DDD resynchronization therapy using adjustable atrio-ventricular delays
US7110817B2 (en) * 1998-05-08 2006-09-19 Cardiac Pacemakers, Inc. Method and apparatus for optimizing ventricular synchrony during DDD resynchronization therapy using adjustable atrio-ventricular delays
US6493579B1 (en) * 1999-08-20 2002-12-10 Cardiac Pacemakers, Inc. System and method for detection enhancement programming
US7127290B2 (en) * 1999-10-01 2006-10-24 Cardiac Pacemakers, Inc. Cardiac rhythm management systems and methods predicting congestive heart failure status
US6640135B1 (en) * 2000-04-06 2003-10-28 Cardiac Pacemakers, Inc. Apparatus and method for spatially and temporally distributing cardiac electrical stimulation
US6751502B2 (en) * 2001-03-14 2004-06-15 Cardiac Pacemakers, Inc. Cardiac rhythm management system with defibrillation threshold prediction
US7386344B2 (en) * 2004-08-11 2008-06-10 Cardiac Pacemakers, Inc. Pacer with combined defibrillator tailored for bradycardia patients
US6684101B2 (en) * 2001-04-25 2004-01-27 Cardiac Pacemakers, Inc. Implantable medical device employing single drive, dual sense impedance measuring
US6628988B2 (en) * 2001-04-27 2003-09-30 Cardiac Pacemakers, Inc. Apparatus and method for reversal of myocardial remodeling with electrical stimulation
US6973349B2 (en) 2001-12-05 2005-12-06 Cardiac Pacemakers, Inc. Method and apparatus for minimizing post-infarct ventricular remodeling
US7127289B2 (en) * 2001-12-05 2006-10-24 Cardiac Pacemakers, Inc. Cardiac resynchronization system employing mechanical measurement of cardiac walls
US6915160B2 (en) * 2002-02-08 2005-07-05 Cardiac Pacemakers, Inc. Dynamically optimized multisite cardiac resynchronization device
US6978171B2 (en) * 2002-03-15 2005-12-20 Medtronic, Inc. Automated impedance measurement of an implantable medical device
SE0200921D0 (en) * 2002-03-25 2002-03-25 St Jude Medical A heart monitoring device, a system including such a device and a lesser use of the system
SE0200922D0 (en) * 2002-03-25 2002-03-25 St Jude Medical A heart monitoring device, a system including such a device and a lesser use of the system
EP1350539B1 (en) * 2002-04-03 2006-10-18 Osypka Medical GmbH Apparatus for automatic determination of hemodynamically optimal cardiac pacing parameter values
US6839592B2 (en) * 2002-04-22 2005-01-04 Medtronic, Inc. Cardiac resynchronization with adaptive A1-A2 and/or V1-V2 intervals
SE0202290D0 (en) * 2002-07-22 2002-07-22 St Jude Medical Monitor
US6965797B2 (en) 2002-09-13 2005-11-15 Cardiac Pacemakers, Inc. Method and apparatus for assessing and treating myocardial wall stress
US7313434B2 (en) * 2002-11-25 2007-12-25 Regents Of The University Of Minnesota Impedance monitoring for detecting pulmonary edema and thoracic congestion
CA2451054A1 (en) * 2002-11-27 2004-05-27 Z-Tech (Canada) Inc. Improved apparatus and method for performing impedance measurements
US7101339B2 (en) * 2002-12-13 2006-09-05 Cardiac Pacemakers, Inc. Respiration signal measurement apparatus, systems, and methods
US7272442B2 (en) 2002-12-30 2007-09-18 Cardiac Pacemakers, Inc. Automatically configurable minute ventilation sensor
US8050764B2 (en) 2003-10-29 2011-11-01 Cardiac Pacemakers, Inc. Cross-checking of transthoracic impedance and acceleration signals
US7149573B2 (en) * 2003-04-25 2006-12-12 Medtronic, Inc. Method and apparatus for impedance signal localizations from implanted devices
US7613513B1 (en) 2003-07-01 2009-11-03 Pacesetter, Inc. System and method for determining cardiac geometry
US7003348B1 (en) 2003-07-01 2006-02-21 Pacesetter, Inc. Monitoring cardiac geometry for diagnostics and therapy
US7200440B2 (en) 2003-07-02 2007-04-03 Cardiac Pacemakers, Inc. Cardiac cycle synchronized sampling of impedance signal
US7010347B2 (en) * 2004-02-14 2006-03-07 Pacesetter, Inc. Optimization of impedance signals for closed loop programming of cardiac resynchronization therapy devices
US7592909B2 (en) * 2006-01-19 2009-09-22 Board Of Regents, The University Of Texas System Location and tracking system using wireless technology
US7065400B2 (en) * 2003-08-20 2006-06-20 Pacesetter, Inc. Method and apparatus for automatically programming CRT devices
EP1510173B1 (en) * 2003-09-01 2017-04-05 BIOTRONIK SE & Co. KG Intracardial impedance measuring device
US7587239B1 (en) 2003-09-24 2009-09-08 Pacesetter, Inc. Cardiac pacemaker system, lead and method for rejecting far-field signals
US9002452B2 (en) 2003-11-07 2015-04-07 Cardiac Pacemakers, Inc. Electrical therapy for diastolic dysfunction
US7184821B2 (en) * 2003-12-03 2007-02-27 Regents Of The University Of Minnesota Monitoring thoracic fluid changes
US7184835B2 (en) * 2003-12-12 2007-02-27 Cardiac Pacemakers, Inc. Method and apparatus for adjustable AVD programming using a table
US7215997B2 (en) * 2003-12-22 2007-05-08 Cardiac Pacemakers, Inc. Dynamic device therapy control for treating post myocardial infarction patients
US7474918B2 (en) * 2004-03-24 2009-01-06 Noninvasive Medical Technologies, Inc. Thoracic impedance monitor and electrode array and method of use
US7505814B2 (en) * 2004-03-26 2009-03-17 Pacesetter, Inc. System and method for evaluating heart failure based on ventricular end-diastolic volume using an implantable medical device
US7272443B2 (en) * 2004-03-26 2007-09-18 Pacesetter, Inc. System and method for predicting a heart condition based on impedance values using an implantable medical device
US7627366B1 (en) 2004-05-17 2009-12-01 Pacesetter, Inc. Analysis of polarization information
US20070191901A1 (en) * 2004-06-04 2007-08-16 Pacesetter, Inc. Quantifying systolic and diastolic cardiac performance from dynamic impedance waveforms
US7356366B2 (en) * 2004-08-02 2008-04-08 Cardiac Pacemakers, Inc. Device for monitoring fluid status
US7212849B2 (en) * 2004-10-28 2007-05-01 Cardiac Pacemakers, Inc. Methods and apparatuses for arrhythmia detection and classification using wireless ECG
US7386345B2 (en) * 2005-01-27 2008-06-10 Cardiac Pacemakers, Inc. Apparatus and method for temporary treatment of acute heart failure decompensation
US7447543B2 (en) * 2005-02-15 2008-11-04 Regents Of The University Of Minnesota Pathology assessment with impedance measurements using convergent bioelectric lead fields
US7366567B2 (en) * 2005-03-23 2008-04-29 Cardiac Pacemakers, Inc. Method for treating myocardial infarction
US7630763B2 (en) 2005-04-20 2009-12-08 Cardiac Pacemakers, Inc. Thoracic or intracardiac impedance detection with automatic vector selection
WO2006119103A2 (en) 2005-04-29 2006-11-09 Medtronic, Inc. Event-based lead impedance monitoring
EP1883450B1 (en) * 2005-04-29 2009-12-09 Medtronic, Inc. Distributed lead functionality testing
US20060271121A1 (en) * 2005-05-25 2006-11-30 Cardiac Pacemakers, Inc. Closed loop impedance-based cardiac resynchronization therapy systems, devices, and methods
US7922669B2 (en) 2005-06-08 2011-04-12 Cardiac Pacemakers, Inc. Ischemia detection using a heart sound sensor
US7711425B2 (en) * 2005-08-22 2010-05-04 Cardiac Pacemakers, Inc. Defibrillation threshold prediction methods and systems
US9839781B2 (en) 2005-08-22 2017-12-12 Cardiac Pacemakers, Inc. Intracardiac impedance and its applications
US8494618B2 (en) * 2005-08-22 2013-07-23 Cardiac Pacemakers, Inc. Intracardiac impedance and its applications
US7974691B2 (en) * 2005-09-21 2011-07-05 Cardiac Pacemakers, Inc. Method and apparatus for controlling cardiac resynchronization therapy using cardiac impedance
US8108034B2 (en) 2005-11-28 2012-01-31 Cardiac Pacemakers, Inc. Systems and methods for valvular regurgitation detection
US8204585B2 (en) * 2005-12-20 2012-06-19 Cardiac Pacemakers, Inc. Bio-impedance sensor and sensing method
US7677503B2 (en) * 2005-12-30 2010-03-16 Thomas & Betts International, Inc. Rework bracket for electrical outlet boxes
US8712519B1 (en) 2006-03-31 2014-04-29 Pacesetter, Inc. Closed-loop adaptive adjustment of pacing therapy based on cardiogenic impedance signals detected by an implantable medical device
US7794404B1 (en) 2006-03-31 2010-09-14 Pacesetter, Inc System and method for estimating cardiac pressure using parameters derived from impedance signals detected by an implantable medical device
US7869871B2 (en) 2006-03-31 2011-01-11 Cardiac Pacemakers, Inc. Pacing therapy for diastolic heart failure
US7890163B2 (en) * 2006-10-19 2011-02-15 Cardiac Pacemakers, Inc. Method and apparatus for detecting fibrillation using cardiac local impedance
US8014863B2 (en) * 2007-01-19 2011-09-06 Cardiac Pacemakers, Inc. Heart attack or ischemia detector
US7840267B2 (en) 2007-03-23 2010-11-23 Cardiac Pacemakers, Inc. Closed-loop resynchronization therapy for mechanical dyssynchrony
US7890167B2 (en) * 2007-04-03 2011-02-15 Cardiac Pacemakers, Inc. Pain free defibrillation threshold estimation
US8521278B2 (en) * 2008-05-08 2013-08-27 Cardiac Pacemakers, Inc. Smart delay for intermittent stress therapy
US9050016B2 (en) * 2009-02-10 2015-06-09 Siemens Medical Solutions Usa, Inc. System for heart performance characterization and abnormality detection
US8983590B2 (en) 2009-05-13 2015-03-17 St. Jude Medical Ab Medical device and method for determining a dyssynchronicity measure technical field
US9462959B2 (en) * 2009-11-20 2016-10-11 Pacesetter, Inc. Methods and systems that use implanted posture sensor to monitor left atrial pressure and/or inter-thoracic fluid volume
US8626278B2 (en) * 2010-10-08 2014-01-07 Euljoon Park Method and system for discriminating and monitoring atrial arrhythmia based on cardiogenic impedance
JP6781044B2 (en) 2014-01-10 2020-11-04 カーディアック ペースメイカーズ, インコーポレイテッド System to detect cardiac arrhythmia
US10449361B2 (en) 2014-01-10 2019-10-22 Cardiac Pacemakers, Inc. Systems and methods for treating cardiac arrhythmias
US10463866B2 (en) 2014-07-11 2019-11-05 Cardiac Pacemakers, Inc. Systems and methods for treating cardiac arrhythmias
WO2016126613A1 (en) 2015-02-06 2016-08-11 Cardiac Pacemakers, Inc. Systems and methods for treating cardiac arrhythmias
US10758737B2 (en) 2016-09-21 2020-09-01 Cardiac Pacemakers, Inc. Using sensor data from an intracardially implanted medical device to influence operation of an extracardially implantable cardioverter
CN114732392A (en) * 2022-04-08 2022-07-12 苏州景昱医疗器械有限公司 Impedance measuring apparatus, system, and computer-readable storage medium

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4674518A (en) * 1985-09-06 1987-06-23 Cardiac Pacemakers, Inc. Method and apparatus for measuring ventricular volume
US5501702A (en) * 1994-06-06 1996-03-26 Medtronic, Inc. Time sharing multipolar rheography apparatus and method
WO1999030777A1 (en) * 1997-12-15 1999-06-24 Medtronic, Inc. Four-chamber pacing system for optimizing cardiac output
EP0990451A2 (en) * 1998-09-28 2000-04-05 Medtronic, Inc. Dual site pacing system with automatic pulse output adjustment
WO2000078391A1 (en) * 1999-06-21 2000-12-28 Cardiac Pacemakers, Inc. Multi-site impedance sensor using coronary sinus/vein electrodes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5154171A (en) * 1991-06-15 1992-10-13 Raul Chirife Rate adaptive pacemaker controlled by ejection fraction
US5466254A (en) 1993-09-22 1995-11-14 Pacesetter, Inc. Coronary sinus lead with atrial sensing capability

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4674518A (en) * 1985-09-06 1987-06-23 Cardiac Pacemakers, Inc. Method and apparatus for measuring ventricular volume
US5501702A (en) * 1994-06-06 1996-03-26 Medtronic, Inc. Time sharing multipolar rheography apparatus and method
WO1999030777A1 (en) * 1997-12-15 1999-06-24 Medtronic, Inc. Four-chamber pacing system for optimizing cardiac output
EP0990451A2 (en) * 1998-09-28 2000-04-05 Medtronic, Inc. Dual site pacing system with automatic pulse output adjustment
WO2000078391A1 (en) * 1999-06-21 2000-12-28 Cardiac Pacemakers, Inc. Multi-site impedance sensor using coronary sinus/vein electrodes

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8010196B1 (en) 2006-03-31 2011-08-30 Pacesetter, Inc. Tissue characterization using intracardiac impedances with an implantable lead system
US8065005B1 (en) 2006-03-31 2011-11-22 Pacesetter, Inc. Tissue characterization using intracardiac impedances with an implantable lead system
US9066662B2 (en) 2007-04-04 2015-06-30 Pacesetter, Inc. System and method for estimating cardiac pressure based on cardiac electrical conduction delays using an implantable medical device
US9113789B2 (en) 2007-04-04 2015-08-25 Pacesetter, Inc. System and method for estimating electrical conduction delays from immittance values measured using an implantable medical device

Also Published As

Publication number Publication date
US20020002389A1 (en) 2002-01-03
AU2001263108A1 (en) 2001-11-26
WO2001087410A2 (en) 2001-11-22

Similar Documents

Publication Publication Date Title
WO2001087410A3 (en) Cardiac stimulation devices and methods for measuring impedances associated with the left side of the heart
US6459929B1 (en) Implantable cardiac rhythm management device for assessing status of CHF patients
US7305266B1 (en) Cardiac stimulation devices and methods for measuring impedances associated with the heart
US9049995B2 (en) System and method for detecting pulmonary congestion based on stroke volume using an implantable medical device
US6473640B1 (en) Implantable device and method for long-term detection and monitoring of congestive heart failure
US6887207B2 (en) Methods and apparatus for estimation of ventricular afterload based on ventricular pressure measurements
EP2648801B1 (en) Admittance measurement for tuning bi-ventricular pacemakers
US5562712A (en) Minute volume rate-responsive pacemaker using dual unipolar leads
US7654964B1 (en) System and method for detecting arterial blood pressure based on aortic electrical resistance using an implantable medical device
US8983592B2 (en) Monitoring fluid in a subject using an electrode configuration providing negative sensitivity regions
US8483817B2 (en) Method and implantable medical device for assessing a degree of pulmonary edema of a patient
US8282562B2 (en) System and method for monitoring cardiopulmonary fluid transfer rates using an implantable medical device
SE0202288D0 (en) A heart stimulator
Braun et al. Impedance cardiography as a noninvasive technique for atrioventricular interval optimization in cardiac resynchronization therapy
US7917204B2 (en) Method and implantable medical device for measuring an electrical bio-impedance of a patient
CA2268892A1 (en) Cardioversion/defibrillation lead impedance measurement system
FR2803759B1 (en) ACTIVE IMPLANTABLE MEDICAL DEVICE, IN PARTICULAR A CARDIAC STIMULATOR, DEFIBRILLATOR AND / OR MULTI-SITE DEVICE PROVIDED WITH MEANS OF MEASUREMENT OF TRANSVALVULAR IMPEDANCE
US8670820B2 (en) Near field-based systems and methods for assessing impedance and admittance for use with an implantable medical device
US9332913B2 (en) System and method for discriminating hypervolemia, hypervolemia and euvolemia using an implantable medical device
WO2001089377A3 (en) Internal cardiac output monitor
US20110087304A1 (en) Method of vagal stimulation to treat patients suffering from congestive heart failure
US8600487B2 (en) System and method for exploiting atrial electrocardiac parameters in assessing left atrial pressure using an implantable medical device
US8521277B2 (en) Implantable systems and method for use therewith for tracking changes in hemodynamics and cardiac disease
JP2012528607A (en) System and method for detection and treatment of decompensation based on patient hemodynamics
JPH09215758A (en) Pacemaker device

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP