WO2001097741A3 - Atrio-ventricular valvular device - Google Patents

Atrio-ventricular valvular device Download PDF

Info

Publication number
WO2001097741A3
WO2001097741A3 PCT/US2001/019602 US0119602W WO0197741A3 WO 2001097741 A3 WO2001097741 A3 WO 2001097741A3 US 0119602 W US0119602 W US 0119602W WO 0197741 A3 WO0197741 A3 WO 0197741A3
Authority
WO
WIPO (PCT)
Prior art keywords
prosthesis
mitral valve
membrane
thin
valve
Prior art date
Application number
PCT/US2001/019602
Other languages
French (fr)
Other versions
WO2001097741A2 (en
Inventor
Carlos M G Duran
Original Assignee
Int Heart Inst Montana
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Int Heart Inst Montana filed Critical Int Heart Inst Montana
Priority to EP01946542A priority Critical patent/EP1296619A2/en
Priority to AU2001268574A priority patent/AU2001268574A1/en
Priority to BR0111860-9A priority patent/BR0111860A/en
Priority to CA002412451A priority patent/CA2412451A1/en
Publication of WO2001097741A2 publication Critical patent/WO2001097741A2/en
Publication of WO2001097741A3 publication Critical patent/WO2001097741A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2496—Devices for determining the dimensions of the prosthetic valve to be implanted, e.g. templates, sizers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2454—Means for preventing inversion of the valve leaflets, e.g. chordae tendineae prostheses
    • A61F2/2457—Chordae tendineae prostheses

Landscapes

  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

An anatomically designed atrioventricular valve is made of biologically compatible synthetic membrane or biological membrane of autologous, homologous or heterologous origin. A single piece of the selected membrane material is trimmed so as to form two unequal sheaths similar to the normal anterior and posterior mammalian mitral valve leaflets with a wide upper base to be sutured to the host's mitral annulus. These two leaflets are prolonged and tapered into two thin bands to be connected to the papillary muscles serving as replacements for the natural marginal chordae tendinae of the normal mitral valve. The two lateral sides of the membrane are joined to form a truncated cone with a wider upper circular base and a narrow extremity formed by the thin chordal bands. A set of sutures are placed between selected points at the base of the cone and the two thin prolongations serving as replacements for the strut or stay basal chords of the natural mitral valve. Thus, the mitral valve prosthesis is anatomical because it is stentless, bicuspid and supported by marginal and basal chordae. Obturators and sizers in the configuration of rods of varying diameter, to measure the host's valve annulus diameter and select the appropriate size of the prosthesis are used during implantation of the prosthesis. A rod shaped holder maintains the prosthesis during implantation, and a curved bodied measuring instrument is used to determine the precise location where the chordae tendinae of the prosthesis are to be sutured to the papillary muscles of a recipient mammal.
PCT/US2001/019602 2000-06-21 2001-06-20 Atrio-ventricular valvular device WO2001097741A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP01946542A EP1296619A2 (en) 2000-06-21 2001-06-20 Heart valve prosthesis
AU2001268574A AU2001268574A1 (en) 2000-06-21 2001-06-20 Atrio-ventricular valvular device
BR0111860-9A BR0111860A (en) 2000-06-21 2001-06-20 Atrioventricular vascular device
CA002412451A CA2412451A1 (en) 2000-06-21 2001-06-20 Atrio-ventricular valvular device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/598,630 US6358277B1 (en) 2000-06-21 2000-06-21 Atrio-ventricular valvular device
US09/598,630 2000-06-21

Publications (2)

Publication Number Publication Date
WO2001097741A2 WO2001097741A2 (en) 2001-12-27
WO2001097741A3 true WO2001097741A3 (en) 2002-09-19

Family

ID=24396331

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/019602 WO2001097741A2 (en) 2000-06-21 2001-06-20 Atrio-ventricular valvular device

Country Status (6)

Country Link
US (1) US6358277B1 (en)
EP (1) EP1296619A2 (en)
AU (1) AU2001268574A1 (en)
BR (1) BR0111860A (en)
CA (1) CA2412451A1 (en)
WO (1) WO2001097741A2 (en)

Families Citing this family (238)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2768324B1 (en) * 1997-09-12 1999-12-10 Jacques Seguin SURGICAL INSTRUMENT FOR PERCUTANEOUSLY FIXING TWO AREAS OF SOFT TISSUE, NORMALLY MUTUALLY REMOTE, TO ONE ANOTHER
US6254564B1 (en) 1998-09-10 2001-07-03 Percardia, Inc. Left ventricular conduit with blood vessel graft
ATE484241T1 (en) * 1999-04-09 2010-10-15 Evalve Inc METHOD AND DEVICE FOR HEART VALVE REPAIR
US6752813B2 (en) 1999-04-09 2004-06-22 Evalve, Inc. Methods and devices for capturing and fixing leaflets in valve repair
US7811296B2 (en) 1999-04-09 2010-10-12 Evalve, Inc. Fixation devices for variation in engagement of tissue
US8216256B2 (en) * 1999-04-09 2012-07-10 Evalve, Inc. Detachment mechanism for implantable fixation devices
US7563267B2 (en) 1999-04-09 2009-07-21 Evalve, Inc. Fixation device and methods for engaging tissue
US20040044350A1 (en) 1999-04-09 2004-03-04 Evalve, Inc. Steerable access sheath and methods of use
US7556646B2 (en) 2001-09-13 2009-07-07 Edwards Lifesciences Corporation Methods and apparatuses for deploying minimally-invasive heart valves
US8091556B2 (en) 2001-04-20 2012-01-10 V-Wave Ltd. Methods and apparatus for reducing localized circulatory system pressure
FR2828263B1 (en) * 2001-08-03 2007-05-11 Philipp Bonhoeffer DEVICE FOR IMPLANTATION OF AN IMPLANT AND METHOD FOR IMPLANTATION OF THE DEVICE
AU2002337598A1 (en) 2001-10-04 2003-04-14 Neovasc Medical Ltd. Flow reducing implant
AU2003217603A1 (en) * 2002-02-20 2003-09-09 Francisco J. Osse Venous bi-valve
US6974464B2 (en) * 2002-02-28 2005-12-13 3F Therapeutics, Inc. Supportless atrioventricular heart valve and minimally invasive delivery systems thereof
US6830586B2 (en) * 2002-02-28 2004-12-14 3F Therapeutics, Inc. Stentless atrioventricular heart valve fabricated from a singular flat membrane
US7048754B2 (en) * 2002-03-01 2006-05-23 Evalve, Inc. Suture fasteners and methods of use
WO2003092554A1 (en) * 2002-05-03 2003-11-13 The General Hospital Corporation Involuted endovascular valve and method of construction
US8348963B2 (en) * 2002-07-03 2013-01-08 Hlt, Inc. Leaflet reinforcement for regurgitant valves
CA2503258C (en) * 2002-08-28 2011-08-16 Heart Leaflet Technologies, Inc. Method and device for treating diseased valve
CO5500017A1 (en) * 2002-09-23 2005-03-31 3F Therapeutics Inc MITRAL PROTESTIC VALVE
AU2003282616B2 (en) * 2002-10-10 2006-06-29 The Cleveland Clinic Foundation Method and apparatus for replacing a mitral valve with a stentless bioprosthetic valve
US20060195182A1 (en) * 2002-10-10 2006-08-31 Navia Jose L Method and apparatus for replacing a mitral valve with a stentless bioprosthetic valve
US7404824B1 (en) * 2002-11-15 2008-07-29 Advanced Cardiovascular Systems, Inc. Valve aptation assist device
US6997950B2 (en) * 2003-01-16 2006-02-14 Chawla Surendra K Valve repair device
US20040162514A1 (en) * 2003-02-14 2004-08-19 Scout Medical Technologies System and method for controlling differential pressure in a cardio-vascular system
US6945996B2 (en) * 2003-04-18 2005-09-20 Sedransk Kyra L Replacement mitral valve
US10646229B2 (en) 2003-05-19 2020-05-12 Evalve, Inc. Fixation devices, systems and methods for engaging tissue
WO2005004753A1 (en) * 2003-06-09 2005-01-20 3F Therapeutics, Inc. Atrioventricular heart valve and minimally invasive delivery systems thereof
KR20050014434A (en) * 2003-07-31 2005-02-07 주식회사 사이언씨티 An Apparatus Sets for Repairing Atrioventricular Valve Insufficiency Due to Ventricular Dilatation
IL158960A0 (en) 2003-11-19 2004-05-12 Neovasc Medical Ltd Vascular implant
AU2011235960B2 (en) * 2004-01-15 2013-01-10 Mount Sinai School Of Medicine Of New York University Devices and methods for repairing cardiac valves
US7488346B2 (en) * 2004-01-21 2009-02-10 The Cleveland Clinic Foundation Method and apparatus for replacing a mitral valve and an aortic valve with a single homograft
US20070038294A1 (en) * 2004-01-21 2007-02-15 Navia Jose L Method and apparatus for replacing a mitral valve and an aortic valve with a homograft
CA2554595C (en) 2004-02-03 2016-03-29 Atria Medical Inc. Device and method for controlling in-vivo pressure
US8206439B2 (en) * 2004-02-23 2012-06-26 International Heart Institute Of Montana Foundation Internal prosthesis for reconstruction of cardiac geometry
EP2308425B2 (en) 2004-03-11 2023-10-18 Percutaneous Cardiovascular Solutions Pty Limited Percutaneous Heart Valve Prosthesis
CA2566666C (en) * 2004-05-14 2014-05-13 Evalve, Inc. Locking mechanisms for fixation devices and methods of engaging tissue
US7635329B2 (en) 2004-09-27 2009-12-22 Evalve, Inc. Methods and devices for tissue grasping and assessment
US8052592B2 (en) * 2005-09-27 2011-11-08 Evalve, Inc. Methods and devices for tissue grasping and assessment
DE102005003632A1 (en) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Catheter for the transvascular implantation of heart valve prostheses
US7462156B2 (en) * 2005-04-11 2008-12-09 Zan Mitrev Replacement aortic valve leaflets and related technology
EP1887980B1 (en) * 2005-05-17 2012-09-05 Cook Medical Technologies LLC Frameless valve prosthesis and system for its deployment
US8685083B2 (en) * 2005-06-27 2014-04-01 Edwards Lifesciences Corporation Apparatus, system, and method for treatment of posterior leaflet prolapse
US7455689B2 (en) * 2005-08-25 2008-11-25 Edwards Lifesciences Corporation Four-leaflet stented mitral heart valve
US8216302B2 (en) * 2005-10-26 2012-07-10 Cardiosolutions, Inc. Implant delivery and deployment system and method
US8778017B2 (en) * 2005-10-26 2014-07-15 Cardiosolutions, Inc. Safety for mitral valve implant
US7785366B2 (en) * 2005-10-26 2010-08-31 Maurer Christopher W Mitral spacer
US8852270B2 (en) * 2007-11-15 2014-10-07 Cardiosolutions, Inc. Implant delivery system and method
US8449606B2 (en) * 2005-10-26 2013-05-28 Cardiosolutions, Inc. Balloon mitral spacer
US9259317B2 (en) * 2008-06-13 2016-02-16 Cardiosolutions, Inc. System and method for implanting a heart implant
US8092525B2 (en) * 2005-10-26 2012-01-10 Cardiosolutions, Inc. Heart valve implant
WO2007058857A2 (en) 2005-11-10 2007-05-24 Arshad Quadri Balloon-expandable, self-expanding, vascular prosthesis connecting stent
KR100711079B1 (en) * 2005-12-29 2007-04-27 주식회사 사이언씨티 An apparatus set for repairing atrioventricular valve insufficiency due to ventricular dilatation
WO2007083288A2 (en) 2006-01-23 2007-07-26 Atria Medical Inc. Heart anchor device
US7749249B2 (en) 2006-02-21 2010-07-06 Kardium Inc. Method and device for closing holes in tissue
US8932348B2 (en) 2006-05-18 2015-01-13 Edwards Lifesciences Corporation Device and method for improving heart valve function
WO2007140470A2 (en) 2006-06-01 2007-12-06 Edwards Lifesciences Corporation Prosthetic insert for improving heart valve function
ITTO20060413A1 (en) * 2006-06-07 2007-12-08 Arrigo Lessana REPLACEMENT DEVICE OF THE TENDONE ROPES OF AN ATRIOVENTRICULAR VALVE
US8449605B2 (en) 2006-06-28 2013-05-28 Kardium Inc. Method for anchoring a mitral valve
US7837610B2 (en) 2006-08-02 2010-11-23 Kardium Inc. System for improving diastolic dysfunction
US20080033541A1 (en) * 2006-08-02 2008-02-07 Daniel Gelbart Artificial mitral valve
US7678144B2 (en) * 2007-01-29 2010-03-16 Cook Incorporated Prosthetic valve with slanted leaflet design
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US8480730B2 (en) * 2007-05-14 2013-07-09 Cardiosolutions, Inc. Solid construct mitral spacer
DE102007043830A1 (en) 2007-09-13 2009-04-02 Lozonschi, Lucian, Madison Heart valve stent
US20090076597A1 (en) * 2007-09-19 2009-03-19 Jonathan Micheal Dahlgren System for mechanical adjustment of medical implants
AU2008305600B2 (en) 2007-09-26 2013-07-04 St. Jude Medical, Inc. Collapsible prosthetic heart valves
WO2009045334A1 (en) 2007-09-28 2009-04-09 St. Jude Medical, Inc. Collapsible/expandable prosthetic heart valves with native calcified leaflet retention features
US8597347B2 (en) * 2007-11-15 2013-12-03 Cardiosolutions, Inc. Heart regurgitation method and apparatus
EP2244668A1 (en) 2008-01-25 2010-11-03 JenaValve Technology Inc. Medical apparatus for the therapeutic treatment of an insufficient cardiac valve
ES2903231T3 (en) 2008-02-26 2022-03-31 Jenavalve Tech Inc Stent for positioning and anchoring a valve prosthesis at an implantation site in a patient's heart
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
DK3967274T3 (en) 2008-04-23 2022-10-03 Medtronic Inc HEART VALVE DEVICES WITH STENT
US20090276040A1 (en) * 2008-05-01 2009-11-05 Edwards Lifesciences Corporation Device and method for replacing mitral valve
US20090287304A1 (en) * 2008-05-13 2009-11-19 Kardium Inc. Medical Device for Constricting Tissue or a Bodily Orifice, for example a mitral valve
US8591460B2 (en) * 2008-06-13 2013-11-26 Cardiosolutions, Inc. Steerable catheter and dilator and system and method for implanting a heart implant
US20100023118A1 (en) * 2008-07-24 2010-01-28 Edwards Lifesciences Corporation Method and apparatus for repairing or replacing chordae tendinae
US8778016B2 (en) * 2008-08-14 2014-07-15 Edwards Lifesciences Corporation Method and apparatus for repairing or replacing chordae tendinae
CN102292053A (en) 2008-09-29 2011-12-21 卡迪尔克阀门技术公司 Heart valve
WO2010040009A1 (en) 2008-10-01 2010-04-08 Cardiaq Valve Technologies, Inc. Delivery system for vascular implant
CN102438546B (en) 2008-11-21 2015-07-15 经皮心血管解决方案公司 Heart valve prosthesis
US9204965B2 (en) 2009-01-14 2015-12-08 Lc Therapeutics, Inc. Synthetic chord
CA2961053C (en) 2009-04-15 2019-04-30 Edwards Lifesciences Cardiaq Llc Vascular implant and delivery system
EP2427143B1 (en) 2009-05-04 2017-08-02 V-Wave Ltd. Device for regulating pressure in a heart chamber
US20210161637A1 (en) 2009-05-04 2021-06-03 V-Wave Ltd. Shunt for redistributing atrial blood volume
US10076403B1 (en) 2009-05-04 2018-09-18 V-Wave Ltd. Shunt for redistributing atrial blood volume
US9034034B2 (en) 2010-12-22 2015-05-19 V-Wave Ltd. Devices for reducing left atrial pressure, and methods of making and using same
US9730790B2 (en) 2009-09-29 2017-08-15 Edwards Lifesciences Cardiaq Llc Replacement valve and method
WO2011041571A2 (en) 2009-10-01 2011-04-07 Kardium Inc. Medical device, kit and method for constricting tissue or a bodily orifice, for example, a mitral valve
JP2013512765A (en) 2009-12-08 2013-04-18 アヴァロン メディカル リミテッド Devices and systems for transcatheter mitral valve replacement
US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
BR112012029896A2 (en) 2010-05-25 2017-06-20 Jenavalve Tech Inc prosthetic heart valve for stent graft and stent graft
US9050066B2 (en) 2010-06-07 2015-06-09 Kardium Inc. Closing openings in anatomical tissue
AU2011271007A1 (en) 2010-06-21 2013-01-31 Cardiaq Valve Technologies, Inc. Replacement heart valve
EP3459500B1 (en) 2010-09-23 2020-09-16 Edwards Lifesciences CardiAQ LLC Replacement heart valves and delivery devices
US8940002B2 (en) 2010-09-30 2015-01-27 Kardium Inc. Tissue anchor system
US8888843B2 (en) 2011-01-28 2014-11-18 Middle Peak Medical, Inc. Device, system, and method for transcatheter treatment of valve regurgitation
US8845717B2 (en) 2011-01-28 2014-09-30 Middle Park Medical, Inc. Coaptation enhancement implant, system, and method
US9072511B2 (en) 2011-03-25 2015-07-07 Kardium Inc. Medical kit for constricting tissue or a bodily orifice, for example, a mitral valve
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US9308087B2 (en) 2011-04-28 2016-04-12 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
US9629715B2 (en) 2011-07-28 2017-04-25 V-Wave Ltd. Devices for reducing left atrial pressure having biodegradable constriction, and methods of making and using same
US11135054B2 (en) 2011-07-28 2021-10-05 V-Wave Ltd. Interatrial shunts having biodegradable material, and methods of making and using same
AU2012299311B2 (en) 2011-08-11 2016-03-03 Tendyne Holdings, Inc. Improvements for prosthetic valves and related inventions
US8945177B2 (en) 2011-09-13 2015-02-03 Abbott Cardiovascular Systems Inc. Gripper pusher mechanism for tissue apposition systems
US9827092B2 (en) 2011-12-16 2017-11-28 Tendyne Holdings, Inc. Tethers for prosthetic mitral valve
EP2811939B8 (en) 2012-02-10 2017-11-15 CVDevices, LLC Products made of biological tissues for stents and methods of manufacturing
US9011515B2 (en) 2012-04-19 2015-04-21 Caisson Interventional, LLC Heart valve assembly systems and methods
US9427315B2 (en) 2012-04-19 2016-08-30 Caisson Interventional, LLC Valve replacement systems and methods
GB201207100D0 (en) * 2012-04-23 2012-06-06 Aortech Internat Plc Valve
US9345573B2 (en) 2012-05-30 2016-05-24 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
US20140005776A1 (en) 2012-06-29 2014-01-02 St. Jude Medical, Cardiology Division, Inc. Leaflet attachment for function in various shapes and sizes
WO2014022124A1 (en) 2012-07-28 2014-02-06 Tendyne Holdings, Inc. Improved multi-component designs for heart valve retrieval device, sealing structures and stent assembly
US9675454B2 (en) 2012-07-30 2017-06-13 Tendyne Holdings, Inc. Delivery systems and methods for transcatheter prosthetic valves
US20140228937A1 (en) 2013-02-11 2014-08-14 Joshua Krieger Expandable Support Frame and Medical Device
US10583002B2 (en) 2013-03-11 2020-03-10 Neovasc Tiara Inc. Prosthetic valve with anti-pivoting mechanism
US20140277427A1 (en) 2013-03-14 2014-09-18 Cardiaq Valve Technologies, Inc. Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery
US9681951B2 (en) 2013-03-14 2017-06-20 Edwards Lifesciences Cardiaq Llc Prosthesis with outer skirt and anchors
US9730791B2 (en) 2013-03-14 2017-08-15 Edwards Lifesciences Cardiaq Llc Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery
US9232998B2 (en) 2013-03-15 2016-01-12 Cardiosolutions Inc. Trans-apical implant systems, implants and methods
US9289297B2 (en) 2013-03-15 2016-03-22 Cardiosolutions, Inc. Mitral valve spacer and system and method for implanting the same
US11224510B2 (en) 2013-04-02 2022-01-18 Tendyne Holdings, Inc. Prosthetic heart valve and systems and methods for delivering the same
US10463489B2 (en) 2013-04-02 2019-11-05 Tendyne Holdings, Inc. Prosthetic heart valve and systems and methods for delivering the same
US9486306B2 (en) 2013-04-02 2016-11-08 Tendyne Holdings, Inc. Inflatable annular sealing device for prosthetic mitral valve
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
US10478293B2 (en) 2013-04-04 2019-11-19 Tendyne Holdings, Inc. Retrieval and repositioning system for prosthetic heart valve
EP2999412B1 (en) 2013-05-21 2020-05-06 V-Wave Ltd. Apparatus for delivering devices for reducing left atrial pressure
US9610159B2 (en) 2013-05-30 2017-04-04 Tendyne Holdings, Inc. Structural members for prosthetic mitral valves
CA2914495A1 (en) * 2013-06-05 2014-12-11 Lc Therapeutics, Inc. Synthetic chord for cardiac valve repair applications
JP6731339B2 (en) 2013-06-14 2020-07-29 カーディオソリューションズ インコーポレイテッドＣａｒｄｉｏｓｏｌｕｔｉｏｎｓ， Ｉｎｃ． Mitral valve spacer and implantation system and method thereof
JP6461122B2 (en) 2013-06-25 2019-01-30 テンダイン ホールディングス，インコーポレイテッド Thrombus management and structural compliance features of prosthetic heart valves
WO2015013666A1 (en) 2013-07-26 2015-01-29 Cardiaq Valve Technologies, Inc. Systems and methods for sealing openings in an anatomical wall
CA2919379C (en) 2013-08-01 2021-03-30 Tendyne Holdings, Inc. Epicardial anchor devices and methods
WO2015028209A1 (en) 2013-08-30 2015-03-05 Jenavalve Technology Gmbh Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
WO2015058039A1 (en) 2013-10-17 2015-04-23 Robert Vidlund Apparatus and methods for alignment and deployment of intracardiac devices
US9050188B2 (en) 2013-10-23 2015-06-09 Caisson Interventional, LLC Methods and systems for heart valve therapy
US10166098B2 (en) 2013-10-25 2019-01-01 Middle Peak Medical, Inc. Systems and methods for transcatheter treatment of valve regurgitation
CN108403261B (en) 2013-10-28 2021-02-12 坦迪尼控股股份有限公司 Prosthetic heart valves and systems and methods for delivering prosthetic heart valves
US9526611B2 (en) 2013-10-29 2016-12-27 Tendyne Holdings, Inc. Apparatus and methods for delivery of transcatheter prosthetic valves
WO2015120122A2 (en) 2014-02-05 2015-08-13 Robert Vidlund Apparatus and methods for transfemoral delivery of prosthetic mitral valve
WO2016126942A2 (en) 2015-02-05 2016-08-11 Vidlund Robert M Expandable epicardial pads and devices and methods for delivery of same
US9986993B2 (en) 2014-02-11 2018-06-05 Tendyne Holdings, Inc. Adjustable tether and epicardial pad system for prosthetic heart valve
EP3107497B1 (en) 2014-02-21 2020-07-22 Edwards Lifesciences CardiAQ LLC Delivery device for controlled deployment of a replacement valve
USD755384S1 (en) 2014-03-05 2016-05-03 Edwards Lifesciences Cardiaq Llc Stent
EP3116409B1 (en) 2014-03-10 2023-07-26 Tendyne Holdings, Inc. Devices for positioning and monitoring tether load for prosthetic mitral valve
US9572666B2 (en) 2014-03-17 2017-02-21 Evalve, Inc. Mitral valve fixation device removal devices and methods
US10390943B2 (en) 2014-03-17 2019-08-27 Evalve, Inc. Double orifice device for transcatheter mitral valve replacement
EP3128952A1 (en) 2014-05-19 2017-02-15 Edwards Lifesciences CardiAQ LLC Replacement mitral valve with annular flap
US9532870B2 (en) 2014-06-06 2017-01-03 Edwards Lifesciences Corporation Prosthetic valve for replacing a mitral valve
US9974647B2 (en) 2014-06-12 2018-05-22 Caisson Interventional, LLC Two stage anchor and mitral valve assembly
ES2908178T3 (en) 2014-06-18 2022-04-28 Polares Medical Inc Mitral valve implants for the treatment of valvular regurgitation
ES2914153T3 (en) 2014-06-24 2022-06-07 Polares Medical Inc Systems to anchor an implant
US9750605B2 (en) 2014-10-23 2017-09-05 Caisson Interventional, LLC Systems and methods for heart valve therapy
US9750607B2 (en) 2014-10-23 2017-09-05 Caisson Interventional, LLC Systems and methods for heart valve therapy
US10188392B2 (en) 2014-12-19 2019-01-29 Abbott Cardiovascular Systems, Inc. Grasping for tissue repair
EP3242630A2 (en) 2015-01-07 2017-11-15 Tendyne Holdings, Inc. Prosthetic mitral valves and apparatus and methods for delivery of same
BR112017019934B1 (en) 2015-03-19 2023-01-17 Caisson Interventional, LLC PROSTHETIC MITRAL VALVE SYSTEM AND ANCHOR ASSEMBLY OF A PROSTHETIC MITRAL VALVE SYSTEM
US10524912B2 (en) 2015-04-02 2020-01-07 Abbott Cardiovascular Systems, Inc. Tissue fixation devices and methods
CA2983002C (en) 2015-04-16 2023-07-04 Tendyne Holdings, Inc. Apparatus and methods for delivery, repositioning, and retrieval of transcatheter prosthetic valves
US10441416B2 (en) 2015-04-21 2019-10-15 Edwards Lifesciences Corporation Percutaneous mitral valve replacement device
US10376363B2 (en) 2015-04-30 2019-08-13 Edwards Lifesciences Cardiaq Llc Replacement mitral valve, delivery system for replacement mitral valve and methods of use
US10709555B2 (en) 2015-05-01 2020-07-14 Jenavalve Technology, Inc. Device and method with reduced pacemaker rate in heart valve replacement
US10940296B2 (en) 2015-05-07 2021-03-09 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Temporary interatrial shunts
US10376673B2 (en) 2015-06-19 2019-08-13 Evalve, Inc. Catheter guiding system and methods
CA2990872C (en) 2015-06-22 2022-03-22 Edwards Lifescience Cardiaq Llc Actively controllable heart valve implant and methods of controlling same
US10092400B2 (en) 2015-06-23 2018-10-09 Edwards Lifesciences Cardiaq Llc Systems and methods for anchoring and sealing a prosthetic heart valve
US10238494B2 (en) 2015-06-29 2019-03-26 Evalve, Inc. Self-aligning radiopaque ring
US10667815B2 (en) 2015-07-21 2020-06-02 Evalve, Inc. Tissue grasping devices and related methods
US10413408B2 (en) 2015-08-06 2019-09-17 Evalve, Inc. Delivery catheter systems, methods, and devices
US10575951B2 (en) 2015-08-26 2020-03-03 Edwards Lifesciences Cardiaq Llc Delivery device and methods of use for transapical delivery of replacement mitral valve
US10117744B2 (en) 2015-08-26 2018-11-06 Edwards Lifesciences Cardiaq Llc Replacement heart valves and methods of delivery
US10350066B2 (en) 2015-08-28 2019-07-16 Edwards Lifesciences Cardiaq Llc Steerable delivery system for replacement mitral valve and methods of use
US10327894B2 (en) 2015-09-18 2019-06-25 Tendyne Holdings, Inc. Methods for delivery of prosthetic mitral valves
US10709560B2 (en) 2015-10-08 2020-07-14 National University Of Singapore Naturally designed mitral prosthesis
US11576771B2 (en) * 2015-10-08 2023-02-14 National University Of Singapore Method for manufacturing personalized naturally designed mitral prosthesis
US10238495B2 (en) 2015-10-09 2019-03-26 Evalve, Inc. Delivery catheter handle and methods of use
US9592121B1 (en) 2015-11-06 2017-03-14 Middle Peak Medical, Inc. Device, system, and method for transcatheter treatment of valvular regurgitation
ES2777609T3 (en) 2015-12-03 2020-08-05 Tendyne Holdings Inc Framework Features for Prosthetic Mitral Valves
WO2017117109A1 (en) 2015-12-28 2017-07-06 Tendyne Holdings, Inc. Atrial pocket closures for prosthetic heart valves
WO2017117388A1 (en) 2015-12-30 2017-07-06 Caisson Interventional, LLC Systems and methods for heart valve therapy
US11058538B2 (en) 2016-03-10 2021-07-13 Charles Somers Living Trust Synthetic chord for cardiac valve repair applications
USD815744S1 (en) 2016-04-28 2018-04-17 Edwards Lifesciences Cardiaq Llc Valve frame for a delivery system
US10470877B2 (en) 2016-05-03 2019-11-12 Tendyne Holdings, Inc. Apparatus and methods for anterior valve leaflet management
CN109475419B (en) 2016-05-13 2021-11-09 耶拿阀门科技股份有限公司 Heart valve prosthesis delivery systems and methods for delivering heart valve prostheses through guide sheaths and loading systems
US10835394B2 (en) 2016-05-31 2020-11-17 V-Wave, Ltd. Systems and methods for making encapsulated hourglass shaped stents
US20170340460A1 (en) 2016-05-31 2017-11-30 V-Wave Ltd. Systems and methods for making encapsulated hourglass shaped stents
US11039921B2 (en) 2016-06-13 2021-06-22 Tendyne Holdings, Inc. Sequential delivery of two-part prosthetic mitral valve
CN109640887B (en) 2016-06-30 2021-03-16 坦迪尼控股股份有限公司 Prosthetic heart valve and apparatus and method for delivering same
US10736632B2 (en) 2016-07-06 2020-08-11 Evalve, Inc. Methods and devices for valve clip excision
US20190240018A1 (en) * 2016-07-06 2019-08-08 The Methodist Hospital Prosthetic mitral valve comprising an annular-ventricular coupling mechanism
WO2018013515A1 (en) 2016-07-12 2018-01-18 Tendyne Holdings, Inc. Apparatus and methods for trans-septal retrieval of prosthetic heart valves
US10350062B2 (en) 2016-07-21 2019-07-16 Edwards Lifesciences Corporation Replacement heart valve prosthesis
CA3033666A1 (en) 2016-08-19 2018-02-22 Edwards Lifesciences Corporation Steerable delivery system for replacement mitral valve and methods of use
EP3964173B1 (en) 2016-08-26 2024-04-10 Edwards Lifesciences Corporation Multi-portion replacement heart valve prosthesis
US11071564B2 (en) 2016-10-05 2021-07-27 Evalve, Inc. Cardiac valve cutting device
CN106618798B (en) * 2016-10-24 2019-10-11 宁波健世生物科技有限公司 A kind of heart valve prosthesis and its conveying and method for releasing fixed by interventricular septum
US10758348B2 (en) 2016-11-02 2020-09-01 Edwards Lifesciences Corporation Supra and sub-annular mitral valve delivery system
US10363138B2 (en) 2016-11-09 2019-07-30 Evalve, Inc. Devices for adjusting the curvature of cardiac valve structures
US10398553B2 (en) 2016-11-11 2019-09-03 Evalve, Inc. Opposing disk device for grasping cardiac valve tissue
US10426616B2 (en) 2016-11-17 2019-10-01 Evalve, Inc. Cardiac implant delivery system
US10779837B2 (en) 2016-12-08 2020-09-22 Evalve, Inc. Adjustable arm device for grasping tissues
US10314586B2 (en) 2016-12-13 2019-06-11 Evalve, Inc. Rotatable device and method for fixing tricuspid valve tissue
CN110392557A (en) 2017-01-27 2019-10-29 耶拿阀门科技股份有限公司 Heart valve simulation
US20190358034A1 (en) * 2017-02-17 2019-11-28 Mitrapex, Inc. Artificial heart valve
EP3585313A4 (en) * 2017-02-23 2020-12-30 University of Pittsburgh - of The Commonwealth System of Higher Education Stentless biopolymer heart valve replacement capable of living tissue regeneration
AU2018228451B2 (en) 2017-03-03 2022-12-08 V-Wave Ltd. Shunt for redistributing atrial blood volume
US11291807B2 (en) 2017-03-03 2022-04-05 V-Wave Ltd. Asymmetric shunt for redistributing atrial blood volume
EP3595587A4 (en) 2017-03-13 2020-11-11 Polares Medical Inc. Device, system, and method for transcatheter treatment of valvular regurgitation
US10478303B2 (en) 2017-03-13 2019-11-19 Polares Medical Inc. Device, system, and method for transcatheter treatment of valvular regurgitation
US10653524B2 (en) 2017-03-13 2020-05-19 Polares Medical Inc. Device, system, and method for transcatheter treatment of valvular regurgitation
US10842619B2 (en) 2017-05-12 2020-11-24 Edwards Lifesciences Corporation Prosthetic heart valve docking assembly
US11065119B2 (en) 2017-05-12 2021-07-20 Evalve, Inc. Long arm valve repair clip
ES2923913T3 (en) 2017-07-06 2022-10-03 Edwards Lifesciences Corp Steerable rail supply system
CN111050702B (en) 2017-07-13 2022-07-05 坦迪尼控股股份有限公司 Prosthetic heart valve and apparatus and method for delivering a prosthetic heart valve
CN111031967B (en) 2017-08-28 2022-08-09 坦迪尼控股股份有限公司 Prosthetic heart valve with tether connection features
CN109893297B (en) * 2017-12-07 2020-11-24 杭州德晋医疗科技有限公司 Artificial chordae tendineae implantation system with clamping auxiliary device
US11744589B2 (en) 2018-01-20 2023-09-05 V-Wave Ltd. Devices and methods for providing passage between heart chambers
US10898698B1 (en) 2020-05-04 2021-01-26 V-Wave Ltd. Devices with dimensions that can be reduced and increased in vivo, and methods of making and using the same
US11458287B2 (en) 2018-01-20 2022-10-04 V-Wave Ltd. Devices with dimensions that can be reduced and increased in vivo, and methods of making and using the same
WO2019144121A1 (en) 2018-01-22 2019-07-25 Edwards Lifesciences Corporation Heart shape preserving anchor
CN117481869A (en) 2018-01-25 2024-02-02 爱德华兹生命科学公司 Delivery system for assisting in recapture and repositioning of replacement valves after deployment
US11051934B2 (en) 2018-02-28 2021-07-06 Edwards Lifesciences Corporation Prosthetic mitral valve with improved anchors and seal
US11517435B2 (en) * 2018-05-04 2022-12-06 Edwards Lifesciences Corporation Ring-based prosthetic cardiac valve
WO2019226803A1 (en) 2018-05-22 2019-11-28 Boston Scientific Scimed, Inc. Percutaneous papillary muscle relocation
US11723783B2 (en) 2019-01-23 2023-08-15 Neovasc Medical Ltd. Covered flow modifying apparatus
US11612385B2 (en) 2019-04-03 2023-03-28 V-Wave Ltd. Systems and methods for delivering implantable devices across an atrial septum
CN114096205A (en) 2019-05-20 2022-02-25 V-波有限责任公司 System and method for creating room shunt tubes
EP3811904A4 (en) * 2019-07-29 2022-04-13 Miyamoto, Shinka Artificial valve forming template and artificial valve
EP3831343B1 (en) 2019-12-05 2024-01-31 Tendyne Holdings, Inc. Braided anchor for mitral valve
US11648114B2 (en) 2019-12-20 2023-05-16 Tendyne Holdings, Inc. Distally loaded sheath and loading funnel
US11951002B2 (en) 2020-03-30 2024-04-09 Tendyne Holdings, Inc. Apparatus and methods for valve and tether fixation
EP4199860A1 (en) 2020-08-19 2023-06-28 Tendyne Holdings, Inc. Fully-transseptal apical pad with pulley for tensioning
EP4203847A4 (en) 2020-08-25 2024-02-28 Shifamed Holdings Llc Adjustable interatrial shunts and associated systems and methods
US11857197B2 (en) 2020-11-12 2024-01-02 Shifamed Holdings, Llc Adjustable implantable devices and associated methods
US11234702B1 (en) 2020-11-13 2022-02-01 V-Wave Ltd. Interatrial shunt having physiologic sensor
US11464634B2 (en) 2020-12-16 2022-10-11 Polares Medical Inc. Device, system, and method for transcatheter treatment of valvular regurgitation with secondary anchors
US11759321B2 (en) 2021-06-25 2023-09-19 Polares Medical Inc. Device, system, and method for transcatheter treatment of valvular regurgitation
WO2023199267A1 (en) 2022-04-14 2023-10-19 V-Wave Ltd. Interatrial shunt with expanded neck region

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5415667A (en) * 1990-06-07 1995-05-16 Frater; Robert W. M. Mitral heart valve replacements

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3739402A (en) * 1970-10-15 1973-06-19 Cutter Lab Bicuspid fascia lata valve
US4790844A (en) * 1987-01-30 1988-12-13 Yoel Ovil Replacement of cardiac valves in heart surgery
US5156621A (en) * 1988-03-22 1992-10-20 Navia Jose A Stentless bioprosthetic cardiac valve
US4960424A (en) * 1988-06-30 1990-10-02 Grooters Ronald K Method of replacing a defective atrio-ventricular valve with a total atrio-ventricular valve bioprosthesis
ES2159508T3 (en) 1991-05-16 2001-10-16 Mures Cardiovascular Res Inc CARDIAC VALVE.
US5733331A (en) * 1992-07-28 1998-03-31 Newcor Industrial S.A. Total mitral heterologous bioprosthesis to be used in mitral or tricuspid heat replacement
US5662704A (en) * 1995-12-01 1997-09-02 Medtronic, Inc. Physiologic mitral valve bioprosthesis
US6630001B2 (en) 1998-06-24 2003-10-07 International Heart Institute Of Montana Foundation Compliant dehyrated tissue for implantation and process of making the same
US6214055B1 (en) * 1998-10-30 2001-04-10 Mures Cardiovascular Research, Inc. Method and kit for rapid preparation of autologous tissue medical devices

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5415667A (en) * 1990-06-07 1995-05-16 Frater; Robert W. M. Mitral heart valve replacements

Also Published As

Publication number Publication date
WO2001097741A2 (en) 2001-12-27
CA2412451A1 (en) 2001-12-27
EP1296619A2 (en) 2003-04-02
AU2001268574A1 (en) 2002-01-02
BR0111860A (en) 2003-05-13
US6358277B1 (en) 2002-03-19

Similar Documents

Publication Publication Date Title
WO2001097741A3 (en) Atrio-ventricular valvular device
DE60322567D1 (en) DEVICE FOR REPLACING A MITRAL FLAP WITH A STAINLESS BIOPROTHETIC FLAP WITH CHORDAE
US8795353B2 (en) Holder devices for annuloplasty devices having a plurality of anterior-posterior ratios
US4340977A (en) Catenary mitral valve replacement
CA2119786C (en) Cardiac valve
AU2001288486B2 (en) Fresh donor heart valve sizer and method of use
US7488346B2 (en) Method and apparatus for replacing a mitral valve and an aortic valve with a single homograft
US6678962B1 (en) Device and method for assessing the geometry of a heart valve
US20070050021A1 (en) Four-leaflet stented mitral heart valve
Gerosa et al. Small aortic annulus: the hydrodynamic performances of 5 commercially available tissue valves
Tasca et al. Comparison of the performance of a sutureless bioprosthesis with two pericardial stented valves on small annuli: an in vitro study
WO2018150392A1 (en) Atrio-ventricular prosthesis with asymmetric flow
US5910169A (en) Total mitral heterologous bioprosthesis to be used in mitral tricuspid heart replacement
Bartek et al. Frame-mounted tissue heart valves: technique of construction
Pomar et al. Mitroflow pericardial bioprosthesis: clinical performance to ten years
CN213758236U (en) Aortic valve annulus internal measuring device
Relland et al. The third generation Carpentier-Edwards bioprosthesis: early results
Punjabi et al. Technique for chordae replacement in mitral valve repair
Jamieson et al. Clinical and hemodynamic performance of the Sorin Mitroflow pericardial bioprosthesis
CN110538004A (en) Durability-enhanced tri-leaflet bioprosthetic valve graft and preparation method thereof
Nagy et al. The effect of sizing on the hydrodynamic parameters of the medtronic freestyle valve in vitro
Kotzé et al. A Semi-Stented and Chorded Mitral Valve Prosthesis: Design and Method of Chordal Setting and In Vitro Testing
Kadri et al. Commissurotomy and bileaflet pericardial augmentation-resuspension for bicuspid aortic valve stenosis
Repossini The Stentless Valve Concept
Glower Bicuspid aortic valve repair: An ongoing struggle in material science

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

WWE Wipo information: entry into national phase

Ref document number: 2412451

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2001946542

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2001946542

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWW Wipo information: withdrawn in national office

Ref document number: 2001946542

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: JP