WO2002007646A3 - Artificial vascular grafts, and methods of producing and using same - Google Patents
Artificial vascular grafts, and methods of producing and using same Download PDFInfo
- Publication number
- WO2002007646A3 WO2002007646A3 PCT/IL2001/000670 IL0100670W WO0207646A3 WO 2002007646 A3 WO2002007646 A3 WO 2002007646A3 IL 0100670 W IL0100670 W IL 0100670W WO 0207646 A3 WO0207646 A3 WO 0207646A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- artificial vascular
- same
- producing
- vascular grafts
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/383—Nerve cells, e.g. dendritic cells, Schwann cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3808—Endothelial cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3826—Muscle cells, e.g. smooth muscle cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
Abstract
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0300810A HUP0300810A2 (en) | 2000-07-20 | 2000-07-20 | Artifical vascular grafts, and methods of producing and using same |
EP01956749A EP1301146B1 (en) | 2000-07-20 | 2001-07-20 | Artificial vascular grafts and methods of producing and using same |
JP2002513384A JP5067822B2 (en) | 2000-07-20 | 2001-07-20 | Artificial vascular graft and its production method and use |
AT01956749T ATE469615T1 (en) | 2000-07-20 | 2001-07-20 | ARTIFICIAL VASCULAR TRANSPLANT AND METHOD FOR THE PRODUCTION AND USE THEREOF |
DE60142290T DE60142290D1 (en) | 2000-07-20 | 2001-07-20 | ARTIFICIAL, VASCULAR TRANSPLANT AND PROCESS FOR ITS MANUFACTURE AND ITS USE |
AU2001278664A AU2001278664A1 (en) | 2000-07-20 | 2001-07-20 | Artificial vascular grafts, and methods of producing and using same |
PL01362561A PL362561A1 (en) | 2000-07-20 | 2001-07-20 | Artificial vascular grafts, and methods of producing and using same |
IL15394601A IL153946A0 (en) | 2000-07-20 | 2001-07-20 | Artificial vascular grafts, and methods of producing and using same |
CA002416548A CA2416548A1 (en) | 2000-07-20 | 2001-07-20 | Artificial vascular grafts, and methods of producing and using same |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62022700A | 2000-07-20 | 2000-07-20 | |
US09/620,227 | 2000-07-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002007646A2 WO2002007646A2 (en) | 2002-01-31 |
WO2002007646A3 true WO2002007646A3 (en) | 2002-06-13 |
Family
ID=24485086
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IL2001/000670 WO2002007646A2 (en) | 2000-07-20 | 2001-07-20 | Artificial vascular grafts, and methods of producing and using same |
Country Status (13)
Country | Link |
---|---|
US (4) | US7364725B1 (en) |
EP (1) | EP1301146B1 (en) |
JP (1) | JP5067822B2 (en) |
AT (1) | ATE469615T1 (en) |
AU (1) | AU2001278664A1 (en) |
CA (1) | CA2416548A1 (en) |
CZ (1) | CZ2003253A3 (en) |
DE (1) | DE60142290D1 (en) |
HU (1) | HUP0300810A2 (en) |
IL (1) | IL153946A0 (en) |
PL (1) | PL362561A1 (en) |
WO (1) | WO2002007646A2 (en) |
ZA (1) | ZA200300635B (en) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6485723B1 (en) | 1995-02-10 | 2002-11-26 | Purdue Research Foundation | Enhanced submucosal tissue graft constructs |
CN100506293C (en) * | 2000-03-15 | 2009-07-01 | 祥丰医疗有限公司 | Coating that promotes endothelial Cell adherence |
HUP0300810A2 (en) | 2000-07-20 | 2003-08-28 | M.G.V.S. Ltd. | Artifical vascular grafts, and methods of producing and using same |
US7175658B1 (en) | 2000-07-20 | 2007-02-13 | Multi-Gene Vascular Systems Ltd. | Artificial vascular grafts, their construction and use |
CA2476917A1 (en) * | 2002-02-19 | 2003-08-28 | Bioarttis, Inc. | Artificial vessel scaffold and artificial organs therefrom |
EP1585426A4 (en) * | 2002-05-02 | 2006-09-20 | Cook Biotech Inc | Cell-seeded extracellular matrix grafts |
AU2003231248B2 (en) | 2002-05-02 | 2009-03-05 | Purdue Research Foundation | Vascularization enhanced graft constructs |
NZ536564A (en) | 2002-05-02 | 2008-05-30 | Purdue Research Foundation | Vascularization enhanced graft constructs which comprise a matrix composition consisting of liver basement membrane |
AU2003234317B2 (en) | 2002-05-02 | 2009-04-09 | Purdue Research Foundation | Vascularization enhanced graft constructs |
EP1740219B1 (en) | 2004-04-30 | 2015-03-04 | OrbusNeich Medical, Inc. | Medical device with coating for capturing genetically-altered cells and methods of using same |
WO2006017275A1 (en) | 2004-07-13 | 2006-02-16 | The University Of Tennessee Research Foundation | Adhesive composition for carrying therapeutic agents as delivery vehicle on coatings applied to vascular grafts |
EP1984040A1 (en) * | 2006-01-31 | 2008-10-29 | Multi Gene Vascular Systems, Inc. | Drug-eluting intravascular prostheses and methods of use |
JP5839814B2 (en) * | 2010-03-17 | 2016-01-06 | グンゼ株式会社 | DANCE protein-containing sustained release substrate and method for producing the sustained release substrate |
EP2575913B1 (en) | 2010-05-25 | 2018-07-25 | Cook Biotech Incorporated | Methods, substrates, and systems useful for cell seeding of medical grafts |
US20140065110A1 (en) | 2012-08-31 | 2014-03-06 | The Regents Of The University Of California | Genetically modified msc and therapeutic methods |
US9663564B2 (en) | 2013-03-15 | 2017-05-30 | The Regents Of The University Of California | Vectors and methods to treat ischemia |
AU2013338051C1 (en) | 2012-10-29 | 2017-08-10 | Ariste Medical, Llc. | Polymer coating compositions and coated products |
US9878071B2 (en) | 2013-10-16 | 2018-01-30 | Purdue Research Foundation | Collagen compositions and methods of use |
GB2528421B (en) | 2014-04-22 | 2016-12-14 | Ariste Medical Inc | Methods and processes for application of drug delivery polymeric coatings |
EP3226886A4 (en) * | 2014-12-07 | 2018-07-25 | Vessl Therapeutics Ltd. | Use of fibulin-5 for the treatment of keloid scars |
WO2016140716A1 (en) | 2015-03-02 | 2016-09-09 | The Trustees Of Columbia University In The City Of New York | Injectable microtissue systems, devices, and methods |
WO2016172365A1 (en) | 2015-04-21 | 2016-10-27 | Purdue Research Foundation Office Of Technology Commercialization | Cell-collagen-silica composites and methods of making and using the same |
CA2992728A1 (en) | 2015-07-20 | 2017-01-26 | Acadia Pharmaceuticals Inc. | Methods for preparing n-(4-fluorobenzyl)-n-(1-methylpiperidin-4-yl)-n'-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and polymorphic form c |
CN106075585B (en) * | 2016-07-08 | 2019-06-21 | 福建师范大学 | A kind of preparation method based on artificial tendon scaffold materials microstructure engineering artificial tendon graft |
US11439731B2 (en) | 2016-09-14 | 2022-09-13 | Revotek Co., Ltd. | Artificial tissue progenitor and method for preparing the same |
CN110331123A (en) * | 2016-09-14 | 2019-10-15 | 四川蓝光英诺生物科技股份有限公司 | Artificial organ precursor and the method for preparing it |
US11739291B2 (en) | 2017-04-25 | 2023-08-29 | Purdue Research Foundation | 3-dimensional (3D) tissue-engineered muscle for tissue restoration |
EP3829603A4 (en) * | 2018-07-27 | 2022-04-27 | Washington University | Cell-embedded vascular graft for transplantation |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5631153A (en) * | 1989-08-22 | 1997-05-20 | University Of Utah | Cells and non-human organisms containing predetermined genomic modifications and positive-negative selection methods and vectors for making same |
US5785965A (en) * | 1996-05-15 | 1998-07-28 | The Board Of Trustees Of The Leland Stanford Junior Univ. | VEGF gene transfer into endothelial cells for vascular prosthesis |
US6010573A (en) * | 1998-07-01 | 2000-01-04 | Virginia Commonwealth University | Apparatus and method for endothelial cell seeding/transfection of intravascular stents |
Family Cites Families (76)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL154600B (en) | 1971-02-10 | 1977-09-15 | Organon Nv | METHOD FOR THE DETERMINATION AND DETERMINATION OF SPECIFIC BINDING PROTEINS AND THEIR CORRESPONDING BINDABLE SUBSTANCES. |
NL154598B (en) | 1970-11-10 | 1977-09-15 | Organon Nv | PROCEDURE FOR DETERMINING AND DETERMINING LOW MOLECULAR COMPOUNDS AND PROTEINS THAT CAN SPECIFICALLY BIND THESE COMPOUNDS AND TEST PACKAGING. |
NL154599B (en) | 1970-12-28 | 1977-09-15 | Organon Nv | PROCEDURE FOR DETERMINING AND DETERMINING SPECIFIC BINDING PROTEINS AND THEIR CORRESPONDING BINDABLE SUBSTANCES, AND TEST PACKAGING. |
US3901654A (en) | 1971-06-21 | 1975-08-26 | Biological Developments | Receptor assays of biologically active compounds employing biologically specific receptors |
US3853987A (en) | 1971-09-01 | 1974-12-10 | W Dreyer | Immunological reagent and radioimmuno assay |
US3867517A (en) | 1971-12-21 | 1975-02-18 | Abbott Lab | Direct radioimmunoassay for antigens and their antibodies |
NL171930C (en) | 1972-05-11 | 1983-06-01 | Akzo Nv | METHOD FOR DETERMINING AND DETERMINING BITES AND TEST PACKAGING. |
US3850578A (en) | 1973-03-12 | 1974-11-26 | H Mcconnell | Process for assaying for biologically active molecules |
US3935074A (en) | 1973-12-17 | 1976-01-27 | Syva Company | Antibody steric hindrance immunoassay with two antibodies |
US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
US4034074A (en) | 1974-09-19 | 1977-07-05 | The Board Of Trustees Of Leland Stanford Junior University | Universal reagent 2-site immunoradiometric assay using labelled anti (IgG) |
US3984533A (en) | 1975-11-13 | 1976-10-05 | General Electric Company | Electrophoretic method of detecting antigen-antibody reaction |
US4098876A (en) | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
US4879219A (en) | 1980-09-19 | 1989-11-07 | General Hospital Corporation | Immunoassay utilizing monoclonal high affinity IgM antibodies |
US5011771A (en) | 1984-04-12 | 1991-04-30 | The General Hospital Corporation | Multiepitopic immunometric assay |
US4736866B1 (en) | 1984-06-22 | 1988-04-12 | Transgenic non-human mammals | |
US4666828A (en) | 1984-08-15 | 1987-05-19 | The General Hospital Corporation | Test for Huntington's disease |
US4801531A (en) | 1985-04-17 | 1989-01-31 | Biotechnology Research Partners, Ltd. | Apo AI/CIII genomic polymorphisms predictive of atherosclerosis |
ES2004281A6 (en) | 1986-04-04 | 1988-12-16 | Univ Jefferson | Method of treating a synthetic naturally occurring surface with a collagen laminate to support microvascular endothelial cell growth, and the surface itself |
ATE132266T1 (en) | 1987-05-01 | 1996-01-15 | Stratagene Inc | MUTAGENEOSIS TESTING USING NON-HUMAN LIVING BEINGS CONTAINING TEST DNA SEQUENCES |
US5175385A (en) | 1987-09-03 | 1992-12-29 | Ohio University/Edison Animal Biotechnolgy Center | Virus-resistant transgenic mice |
US6001350A (en) | 1987-12-11 | 1999-12-14 | Somatix Therapy Corp | Genetic modification of endothelial cells |
US5674722A (en) * | 1987-12-11 | 1997-10-07 | Somatix Therapy Corporation | Genetic modification of endothelial cells |
US5221778A (en) | 1988-08-24 | 1993-06-22 | Yale University | Multiplex gene regulation |
US5272057A (en) | 1988-10-14 | 1993-12-21 | Georgetown University | Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase |
US5175384A (en) | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
US5175383A (en) | 1989-02-17 | 1992-12-29 | President And Fellows Of Harvard College | Animal model for benign prostatic disease |
US5272263A (en) * | 1989-04-28 | 1993-12-21 | Biogen, Inc. | DNA sequences encoding vascular cell adhesion molecules (VCAMS) |
US5192659A (en) | 1989-08-25 | 1993-03-09 | Genetype Ag | Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes |
US5498238A (en) | 1990-06-15 | 1996-03-12 | Cortrak Medical, Inc. | Simultaneous angioplasty and phoretic drug delivery |
AU646877B2 (en) | 1990-06-15 | 1994-03-10 | Scios Nova Inc. | Transgenic non-human mammal displaying the amyloid-forming pathology of alzheimer's disease |
US5288846A (en) | 1990-10-19 | 1994-02-22 | The General Hospital Corporation | Cell specific gene regulators |
WO1992011895A1 (en) | 1990-12-28 | 1992-07-23 | Boston Scientific Corporation | Balloon drug delivery system |
US5298422A (en) | 1991-11-06 | 1994-03-29 | Baylor College Of Medicine | Myogenic vector systems |
US5925564A (en) | 1991-11-06 | 1999-07-20 | Baylor College Of Medicine | Expression vector systems and method of use |
EP0620849B1 (en) | 1992-01-07 | 2003-06-25 | Elan Pharmaceuticals, Inc. | Transgenic animal models for alzheimer's disease |
US5360735A (en) | 1992-01-08 | 1994-11-01 | Synaptic Pharmaceutical Corporation | DNA encoding a human 5-HT1F receptor, vectors, and host cells |
US5599352A (en) | 1992-03-19 | 1997-02-04 | Medtronic, Inc. | Method of making a drug eluting stent |
US5281521A (en) | 1992-07-20 | 1994-01-25 | The Trustees Of The University Of Pennsylvania | Modified avidin-biotin technique |
EP0663952A4 (en) | 1992-09-11 | 1997-06-11 | Univ California | Transgenic non-human animals having targeted lymphocyte transduction genes. |
US5634901A (en) | 1992-11-02 | 1997-06-03 | Localmed, Inc. | Method of using a catheter sleeve |
WO1994023049A2 (en) | 1993-04-02 | 1994-10-13 | The Johns Hopkins University | The introduction and expression of large genomic sequences in transgenic animals |
US6664107B1 (en) | 1993-05-26 | 2003-12-16 | Ontario Cancer Institute, University Health Network | CD45 disrupted nucleic acid |
PT711158E (en) | 1993-07-29 | 2004-04-30 | Us Gov Health & Human Serv | METHOD FOR TREATING ATHEROSCLEROSIS OR RESTENING USING A MICROTUBLE STABILIZING AGENT |
US5736360A (en) * | 1993-09-10 | 1998-04-07 | The Trustees Of The University Of Pennsylvania | Endothelial cell tropic compositions and methods of making and using the same |
WO1995025547A1 (en) * | 1994-03-24 | 1995-09-28 | University Of Washington | Devices and methods for implanting transduced cells |
US5700346A (en) * | 1994-07-19 | 1997-12-23 | Edwards; Peter S. | Automated slide staining system |
US6425881B1 (en) | 1994-10-05 | 2002-07-30 | Nitrosystems, Inc. | Therapeutic mixture useful in inhibiting lesion formation after vascular injury |
EP1181904B1 (en) | 1994-10-17 | 2009-06-24 | Kabushikikaisha Igaki Iryo Sekkei | Stent for liberating drug |
US20020026037A1 (en) * | 1995-06-06 | 2002-02-28 | Jing-Shan Hu | Vascular endothelial growth factor 3 antibodies |
EP0871512A1 (en) | 1995-12-22 | 1998-10-21 | Localmed, Inc. | Localized intravascular delivery of growth factors for promotion of angiogenesis |
ES2274549T3 (en) * | 1996-09-24 | 2007-05-16 | MERCK & CO., INC. | COMPOUNDS FOR THE INHIBITION OF ANGIOGENESIS BY GENES THERAPY. |
WO1998044938A1 (en) * | 1997-04-10 | 1998-10-15 | University Of Southern California | Modified proteins which bind extracellular matrix components |
WO1998056312A1 (en) | 1997-06-13 | 1998-12-17 | Scimed Life Systems, Inc. | Stents having multiple layers of biodegradable polymeric composition |
US5872234A (en) | 1997-06-27 | 1999-02-16 | Incyte Pharmaceuticals, Inc. | Human extracellular matrix proteins |
US5899935A (en) | 1997-08-04 | 1999-05-04 | Schneider (Usa) Inc. | Balloon expandable braided stent with restraint |
US6077987A (en) | 1997-09-04 | 2000-06-20 | North Shore-Long Island Jewish Research Institute | Genetic engineering of cells to enhance healing and tissue regeneration |
WO1999040197A2 (en) * | 1998-02-06 | 1999-08-12 | Collateral Therapeutics, Inc. | Variants of the angiogenic factor vascular endothelial cell growth factor: vegf |
US6364856B1 (en) | 1998-04-14 | 2002-04-02 | Boston Scientific Corporation | Medical device with sponge coating for controlled drug release |
US6846647B1 (en) | 1998-04-28 | 2005-01-25 | Ono Pharmaceutical Co., Ltd. | Polypeptides suppressing smooth muscle cell proliferation, the encoding cDNA, and related methods |
EP1568375A1 (en) | 1998-10-26 | 2005-08-31 | Ludwig Institute For Cancer Research | Use of VEGF-C or VEGF-D gene or protein to prevent restenosis |
US6328762B1 (en) * | 1999-04-27 | 2001-12-11 | Sulzer Biologics, Inc. | Prosthetic grafts |
US6554857B1 (en) | 1999-07-20 | 2003-04-29 | Medtronic, Inc | Transmural concentric multilayer ingrowth matrix within well-defined porosity |
US6589534B1 (en) * | 1999-09-30 | 2003-07-08 | Yeda Research And Development Co., Ltd. | Hepatitis B virus binding proteins and uses thereof |
US6716242B1 (en) | 1999-10-13 | 2004-04-06 | Peter A. Altman | Pulmonary vein stent and method for use |
US20030229393A1 (en) | 2001-03-15 | 2003-12-11 | Kutryk Michael J. B. | Medical device with coating that promotes cell adherence and differentiation |
US7175658B1 (en) * | 2000-07-20 | 2007-02-13 | Multi-Gene Vascular Systems Ltd. | Artificial vascular grafts, their construction and use |
HUP0300810A2 (en) * | 2000-07-20 | 2003-08-28 | M.G.V.S. Ltd. | Artifical vascular grafts, and methods of producing and using same |
US6939376B2 (en) | 2001-11-05 | 2005-09-06 | Sun Biomedical, Ltd. | Drug-delivery endovascular stent and method for treating restenosis |
EP1578352A2 (en) | 2002-03-27 | 2005-09-28 | University of Utah Research Foundation | Elastin prevents occlusion of body vessels by vascular smooth muscle cells |
US20040126788A1 (en) | 2002-08-13 | 2004-07-01 | Schiemann William P. | Fibulin-5 and uses thereof |
US6918929B2 (en) | 2003-01-24 | 2005-07-19 | Medtronic Vascular, Inc. | Drug-polymer coated stent with pegylated styrenic block copolymers |
CA2561495A1 (en) | 2004-03-29 | 2005-10-06 | Kyoto University | Truncated dance, dance complex and method of using these |
WO2005099695A1 (en) | 2004-04-19 | 2005-10-27 | Novartis Ag | Drug delivery systems for the prevention and treatment of vascular diseases |
US9074175B2 (en) | 2005-02-07 | 2015-07-07 | Nb Health Laboratory Co., Ltd. | Method of regenerating elastic fiber with the use of dance or factor enhancing the expression thereof |
EP1984040A1 (en) | 2006-01-31 | 2008-10-29 | Multi Gene Vascular Systems, Inc. | Drug-eluting intravascular prostheses and methods of use |
-
2000
- 2000-07-20 HU HU0300810A patent/HUP0300810A2/en unknown
-
2001
- 2001-07-20 DE DE60142290T patent/DE60142290D1/en not_active Expired - Lifetime
- 2001-07-20 CA CA002416548A patent/CA2416548A1/en not_active Abandoned
- 2001-07-20 PL PL01362561A patent/PL362561A1/en unknown
- 2001-07-20 WO PCT/IL2001/000670 patent/WO2002007646A2/en not_active Application Discontinuation
- 2001-07-20 JP JP2002513384A patent/JP5067822B2/en not_active Expired - Fee Related
- 2001-07-20 AU AU2001278664A patent/AU2001278664A1/en not_active Abandoned
- 2001-07-20 EP EP01956749A patent/EP1301146B1/en not_active Expired - Lifetime
- 2001-07-20 AT AT01956749T patent/ATE469615T1/en not_active IP Right Cessation
- 2001-07-20 IL IL15394601A patent/IL153946A0/en unknown
- 2001-07-20 CZ CZ2003253A patent/CZ2003253A3/en unknown
-
2002
- 2002-06-04 US US10/163,387 patent/US7364725B1/en not_active Expired - Fee Related
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2003
- 2003-01-23 ZA ZA200300635A patent/ZA200300635B/en unknown
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2006
- 2006-01-31 US US11/344,870 patent/US7563278B2/en not_active Expired - Fee Related
-
2008
- 2008-03-13 US US12/075,657 patent/US8022195B2/en not_active Expired - Fee Related
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2009
- 2009-06-02 US US12/455,521 patent/US8088160B2/en not_active Expired - Fee Related
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5631153A (en) * | 1989-08-22 | 1997-05-20 | University Of Utah | Cells and non-human organisms containing predetermined genomic modifications and positive-negative selection methods and vectors for making same |
US5785965A (en) * | 1996-05-15 | 1998-07-28 | The Board Of Trustees Of The Leland Stanford Junior Univ. | VEGF gene transfer into endothelial cells for vascular prosthesis |
US6010573A (en) * | 1998-07-01 | 2000-01-04 | Virginia Commonwealth University | Apparatus and method for endothelial cell seeding/transfection of intravascular stents |
Also Published As
Publication number | Publication date |
---|---|
US7563278B2 (en) | 2009-07-21 |
CA2416548A1 (en) | 2002-01-31 |
IL153946A0 (en) | 2003-07-31 |
AU2001278664A1 (en) | 2002-02-05 |
US20090263452A1 (en) | 2009-10-22 |
DE60142290D1 (en) | 2010-07-15 |
CZ2003253A3 (en) | 2003-05-14 |
ATE469615T1 (en) | 2010-06-15 |
JP2004506418A (en) | 2004-03-04 |
US7364725B1 (en) | 2008-04-29 |
US20060275338A1 (en) | 2006-12-07 |
WO2002007646A2 (en) | 2002-01-31 |
EP1301146A2 (en) | 2003-04-16 |
ZA200300635B (en) | 2004-04-22 |
JP5067822B2 (en) | 2012-11-07 |
HUP0300810A2 (en) | 2003-08-28 |
US8088160B2 (en) | 2012-01-03 |
EP1301146A4 (en) | 2008-11-19 |
PL362561A1 (en) | 2004-11-02 |
US20080269472A1 (en) | 2008-10-30 |
US8022195B2 (en) | 2011-09-20 |
EP1301146B1 (en) | 2010-06-02 |
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