WO2002013697A8 - Obstructive sleep apnea event detecting system and method - Google Patents

Obstructive sleep apnea event detecting system and method

Info

Publication number
WO2002013697A8
WO2002013697A8 PCT/US2001/041781 US0141781W WO0213697A8 WO 2002013697 A8 WO2002013697 A8 WO 2002013697A8 US 0141781 W US0141781 W US 0141781W WO 0213697 A8 WO0213697 A8 WO 0213697A8
Authority
WO
WIPO (PCT)
Prior art keywords
sleep apnea
obstructive sleep
apnea event
breathing
detecting system
Prior art date
Application number
PCT/US2001/041781
Other languages
French (fr)
Other versions
WO2002013697A1 (en
Inventor
Michael L Lehrman
Michael E Halleck
Original Assignee
Ilife Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ilife Systems Inc filed Critical Ilife Systems Inc
Priority to AU2001287193A priority Critical patent/AU2001287193A1/en
Publication of WO2002013697A1 publication Critical patent/WO2002013697A1/en
Publication of WO2002013697A8 publication Critical patent/WO2002013697A8/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B7/00Instruments for auscultation
    • A61B7/003Detecting lung or respiration noise
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813Specially adapted to be attached to a specific body part
    • A61B5/6822Neck
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/087Measuring breath flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4806Sleep evaluation
    • A61B5/4818Sleep apnoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/7253Details of waveform analysis characterised by using transforms
    • A61B5/7257Details of waveform analysis characterised by using transforms using Fourier transforms

Abstract

A system (100) and method for detecting the onset of an obstructive sleep apnea event before the obstructive sleep apnea event fully develops and before the cessation of breathing occurs. The system (100) comprises one or more microphones (125, 130, 135, 140) capable of detecting breathing sounds within an airway of a person (120). The microphones (125, 130, 135, 140) generate signals representative of the breathing sounds and send the signals to a controller (230). The controller (230) identifies at least one signal pattern that is associated with a breathing pattern of the person (120) that occurs at the onset of an obstructive sleep apnea event. The controller (230) may also identify at least one signal pattern that is associated with a partially occluded breathing pattern of the person (120).
PCT/US2001/041781 2000-08-17 2001-08-17 Obstructive sleep apnea event detecting system and method WO2002013697A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001287193A AU2001287193A1 (en) 2000-08-17 2001-08-17 System and method for detecting the onset of an obstructive sleep apnea event

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/641,982 2000-08-17
US09/641,982 US6666830B1 (en) 2000-08-17 2000-08-17 System and method for detecting the onset of an obstructive sleep apnea event

Publications (2)

Publication Number Publication Date
WO2002013697A1 WO2002013697A1 (en) 2002-02-21
WO2002013697A8 true WO2002013697A8 (en) 2002-07-18

Family

ID=24574653

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/041781 WO2002013697A1 (en) 2000-08-17 2001-08-17 Obstructive sleep apnea event detecting system and method

Country Status (5)

Country Link
US (2) US6666830B1 (en)
AR (1) AR030367A1 (en)
AU (1) AU2001287193A1 (en)
TW (1) TW579290B (en)
WO (1) WO2002013697A1 (en)

Families Citing this family (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP996499A0 (en) 1999-04-23 1999-05-20 Australian Centre For Advanced Medical Technology Ltd A treatment for hypertension caused by pre-eclampsia
CN1431886A (en) 2000-04-20 2003-07-23 帕默索里克私营有限公司 Method and appts. for determining conditions of biological tissues
US7708697B2 (en) 2000-04-20 2010-05-04 Pulmosonix Pty Ltd Method and apparatus for determining conditions of biological tissues
US6666830B1 (en) * 2000-08-17 2003-12-23 East River Ventures, Lp System and method for detecting the onset of an obstructive sleep apnea event
US6935335B1 (en) * 2000-08-17 2005-08-30 Ilife Systems, Inc. System and method for treating obstructive sleep apnea
US6814073B2 (en) 2000-08-29 2004-11-09 Resmed Limited Respiratory apparatus with improved flow-flattening detection
US6942699B2 (en) 2001-07-11 2005-09-13 Biomet, Inc. Shoulder prosthesis
US7841987B2 (en) * 2004-03-30 2010-11-30 Apneos Corporation System and method for visualizing sleep-related information
US20060155205A1 (en) * 2003-11-24 2006-07-13 Apneos Corp. System and method for assessing breathing
EP1538970B1 (en) 2002-08-09 2020-06-17 Intercure Ltd. Generalized metronome for modification of biorhythmic activity
US8467876B2 (en) 2003-10-15 2013-06-18 Rmx, Llc Breathing disorder detection and therapy delivery device and method
US8140164B2 (en) 2003-10-15 2012-03-20 Rmx, Llc Therapeutic diaphragm stimulation device and method
US20060167523A1 (en) * 2003-10-15 2006-07-27 Tehrani Amir J Device and method for improving upper airway functionality
US8244358B2 (en) * 2003-10-15 2012-08-14 Rmx, Llc Device and method for treating obstructive sleep apnea
US8265759B2 (en) 2003-10-15 2012-09-11 Rmx, Llc Device and method for treating disorders of the cardiovascular system or heart
US9259573B2 (en) 2003-10-15 2016-02-16 Rmx, Llc Device and method for manipulating exhalation
US7970475B2 (en) 2003-10-15 2011-06-28 Rmx, Llc Device and method for biasing lung volume
US8160711B2 (en) 2003-10-15 2012-04-17 Rmx, Llc Multimode device and method for controlling breathing
US7979128B2 (en) 2003-10-15 2011-07-12 Rmx, Llc Device and method for gradually controlling breathing
TWI250326B (en) * 2003-11-28 2006-03-01 Prime Optical Fiber Corp Optical fiber inclinometer
US8491492B2 (en) 2004-02-05 2013-07-23 Earlysense Ltd. Monitoring a condition of a subject
US8942779B2 (en) 2004-02-05 2015-01-27 Early Sense Ltd. Monitoring a condition of a subject
US7314451B2 (en) * 2005-04-25 2008-01-01 Earlysense Ltd. Techniques for prediction and monitoring of clinical episodes
US8403865B2 (en) 2004-02-05 2013-03-26 Earlysense Ltd. Prediction and monitoring of clinical episodes
JP4809779B2 (en) * 2004-02-05 2011-11-09 アーリーセンス・リミテッド Prediction and monitoring technology for clinical onset in respiration
MXPA06009516A (en) * 2004-02-24 2007-03-26 Microdose Technologies Inc Directional flow sensor inhaler.
US8226569B2 (en) 2004-05-26 2012-07-24 Sotos John G System and method for managing sleep disorders
KR20070048201A (en) 2004-07-23 2007-05-08 인터큐어 엘티디 Apparatus and method for breathing pattern determination using a non-contact microphone
US7469698B1 (en) 2004-09-14 2008-12-30 Winthrop De Childers Parameter optimization in sleep apnea treatment apparatus
US8578937B2 (en) 2004-09-21 2013-11-12 Medtronic Xomed, Inc. Smart mandibular repositioning system
US20090048500A1 (en) * 2005-04-20 2009-02-19 Respimetrix, Inc. Method for using a non-invasive cardiac and respiratory monitoring system
US20060243280A1 (en) * 2005-04-27 2006-11-02 Caro Richard G Method of determining lung condition indicators
WO2006117780A2 (en) 2005-04-29 2006-11-09 Oren Gavriely Cough detector
US20060276701A1 (en) * 2005-06-03 2006-12-07 Ray Charles D Detection and stimulus conditioning system for sleep apnea
DE102005053109A1 (en) * 2005-11-04 2007-05-10 Koehler, Ullrich, Prof. Dr. Body noise detection
US20080308112A1 (en) * 2005-12-20 2008-12-18 Koninklijke Philips Electronics, N.V. System and Method for Reducing Snoring and/or Sleep Apnea of Sleeping Person
US9779751B2 (en) * 2005-12-28 2017-10-03 Breath Research, Inc. Respiratory biofeedback devices, systems, and methods
WO2007079068A2 (en) * 2005-12-28 2007-07-12 Nirinjan Bikko Breathing biofeedback device
CA2641821C (en) 2006-02-16 2017-10-10 Imthera Medical, Inc. An rfid-based apparatus, system, and method for therapeutic treatment of a patient
GB0604138D0 (en) 2006-03-01 2006-04-12 Imp College Innovations Ltd A method and apparatus for monitoring respiratory activity
DE102006017279A1 (en) 2006-04-12 2007-10-18 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Automatic detection of hypopneas
DE102006017278A1 (en) * 2006-04-12 2007-10-18 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Proof of onset of apnea
US8280513B2 (en) 2006-12-22 2012-10-02 Rmx, Llc Device and method to treat flow limitations
US20080195173A1 (en) * 2007-02-14 2008-08-14 Canzzz Investments Ltd. Method and Apparatus for Treating Sleep Apnea and Snoring
US20080243017A1 (en) * 2007-03-28 2008-10-02 Zahra Moussavi Breathing sound analysis for estimation of airlow rate
US8585607B2 (en) 2007-05-02 2013-11-19 Earlysense Ltd. Monitoring, predicting and treating clinical episodes
US7974689B2 (en) 2007-06-13 2011-07-05 Zoll Medical Corporation Wearable medical treatment device with motion/position detection
US8140154B2 (en) * 2007-06-13 2012-03-20 Zoll Medical Corporation Wearable medical treatment device
AU2008311312A1 (en) 2007-10-09 2009-04-16 Imthera Medical, Inc. Apparatus, system, and method for selective stimulation
US20170188940A9 (en) 2007-11-26 2017-07-06 Whispersom Corporation Device to detect and treat Apneas and Hypopnea
DE102007063007A1 (en) * 2007-12-21 2009-06-25 Kouemou, Guy Leonard, Dr. Ing. Method and device for sleep diagnosis and therapy monitoring
US9883809B2 (en) 2008-05-01 2018-02-06 Earlysense Ltd. Monitoring, predicting and treating clinical episodes
US8882684B2 (en) 2008-05-12 2014-11-11 Earlysense Ltd. Monitoring, predicting and treating clinical episodes
JP2012502671A (en) 2008-05-12 2012-02-02 アーリーセンス エルティディ Monitoring, prediction and treatment of clinical symptoms
US8428725B2 (en) 2008-10-09 2013-04-23 Imthera Medical, Inc. Method of stimulating a Hypoglossal nerve for controlling the position of a patient's tongue
JP4935931B2 (en) * 2008-10-16 2012-05-23 富士通株式会社 Apnea detection program and apnea detection device
EP2348993B1 (en) * 2008-11-17 2016-06-08 University Health Network Method and apparatus for monitoring breathing cycle by frequency analysis of an acoustic data stream
US20100125224A1 (en) * 2008-11-17 2010-05-20 Aniekan Umana Medical diagnosis method and medical diagnostic system
JP5575789B2 (en) 2008-11-19 2014-08-20 インスパイア・メディカル・システムズ・インコーポレイテッド How to treat sleep-disordered breathing
EP3632491B1 (en) * 2009-02-11 2023-04-19 ResMed Pty Ltd Acoustic detection for respiratory treatment apparatus
EP2457504B1 (en) 2009-07-24 2014-07-16 Fujitsu Limited Sleep apnea syndrome examination device and program
BR112012005738A2 (en) * 2009-09-14 2016-03-08 Sleep Methods system and method for anticipating the onset of an obstructive sleep apnea event
EP2477689A4 (en) * 2009-09-14 2014-12-03 Sleep Methods System and method for training and promoting a conditioned reflex intervention during sleep
BR112012010986A2 (en) 2009-11-10 2016-04-12 Imthera Medical Inc system to stimulate a hypoglossal nerve to control a patient's tongue position
US20110172552A1 (en) * 2010-01-12 2011-07-14 Vanderbilt University Acoustic sleep apnea monitor
US8844537B1 (en) 2010-10-13 2014-09-30 Michael T. Abramson System and method for alleviating sleep apnea
US10292625B2 (en) 2010-12-07 2019-05-21 Earlysense Ltd. Monitoring a sleeping subject
US9427564B2 (en) 2010-12-16 2016-08-30 Zoll Medical Corporation Water resistant wearable medical device
WO2013023218A1 (en) 2011-08-11 2013-02-14 Inspire Medical Systems, Inc. System for selecting a stimulation protocol based on sensed respiratory effort
CN104039515B (en) 2011-10-20 2016-08-17 艾伯特·凡格拉 For cutting the handheld tool of laminated glass
CN103889324B (en) 2011-10-20 2017-05-17 皇家飞利浦有限公司 A system and method for characterizing an upper airway using speech characteristics
US8959082B2 (en) 2011-10-31 2015-02-17 Elwha Llc Context-sensitive query enrichment
US8702804B2 (en) * 2011-12-02 2014-04-22 Biomet Manufacturing, Llc Variable prosthesis
US8892205B2 (en) * 2011-12-07 2014-11-18 Otologics, Llc Sleep apnea control device
US10426426B2 (en) 2012-06-18 2019-10-01 Breathresearch, Inc. Methods and apparatus for performing dynamic respiratory classification and tracking
US9814438B2 (en) * 2012-06-18 2017-11-14 Breath Research, Inc. Methods and apparatus for performing dynamic respiratory classification and tracking
DE102012219128B4 (en) * 2012-10-19 2016-06-02 Pateca GmbH Method and system for determining anatomical causes for the development of snoring sounds
US9687193B2 (en) * 2013-02-09 2017-06-27 Ali Mireshghi Sleep apnea avoidance and data collection device
WO2014143743A1 (en) 2013-03-15 2014-09-18 Zansors Llc Health monitoring, surveillance and anomaly detection
US11712557B2 (en) 2013-05-30 2023-08-01 Neurostim Technologies Llc Detection and treatment of obstructive sleep apnea
US9603573B2 (en) 2014-04-14 2017-03-28 Brain Sentinel, Inc. Detection of EMG activity using sensors on both sides of the body
WO2016033245A1 (en) 2014-08-26 2016-03-03 Rmx, Llc Devices and methods for reducing intrathoracic pressure
WO2016029869A1 (en) * 2014-08-29 2016-03-03 莱镁医疗器材股份有限公司 Sleep quality detection device
WO2016040914A1 (en) 2014-09-12 2016-03-17 Brain Sentinel, Inc. Method and apparatus for communication between a sensor and a managing device
EP3271008A1 (en) 2015-03-19 2018-01-24 Inspire Medical Systems, Inc. Stimulation for treating sleep disordered breathing
US10729910B2 (en) 2015-11-23 2020-08-04 Zoll Medical Corporation Garments for wearable medical devices
WO2017167630A1 (en) * 2016-03-31 2017-10-05 Koninklijke Philips N.V. System and method for detecting a breathing pattern
CN105901808B (en) * 2016-05-27 2017-12-01 祁德元 Multifunctional intellectual collar
US11009870B2 (en) 2017-06-06 2021-05-18 Zoll Medical Corporation Vehicle compatible ambulatory defibrillator
CN107361770A (en) * 2017-08-15 2017-11-21 杭州医电园科技有限公司 Sleep apnea event discriminating gear
WO2020069308A1 (en) 2018-09-28 2020-04-02 Zoll Medical Corporation Adhesively coupled wearable medical device
US11568984B2 (en) 2018-09-28 2023-01-31 Zoll Medical Corporation Systems and methods for device inventory management and tracking
EP3902598A1 (en) 2018-12-28 2021-11-03 Zoll Medical Corporation Wearable medical device response mechanisms and methods of use
US11266837B2 (en) 2019-03-06 2022-03-08 Medtronic Xomed, Inc. Position sensitive lingual muscle simulation system for obstructive sleep apnea
US11478638B2 (en) 2019-03-22 2022-10-25 Neurostim Technologies Llc Detection and treatment of obstructive sleep apnea
US11305110B2 (en) 2019-03-22 2022-04-19 Neurostim Technologies Llc Detection and treatment of obstructive sleep apnea
CA3139944A1 (en) * 2019-05-15 2020-11-19 Appscent Medical Ltd Device and method to selectively provide an odor stimulation
US11266838B1 (en) 2019-06-21 2022-03-08 Rmx, Llc Airway diagnostics utilizing phrenic nerve stimulation device and method
WO2021222897A2 (en) * 2020-05-01 2021-11-04 The Brigham And Women's Hospital, Inc. System and method for endo-phenotyping and risk stratfying obstructive sleep apnea

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4602644A (en) * 1982-08-18 1986-07-29 Plasmedics, Inc. Physiological detector and monitor
US4715367A (en) * 1986-09-15 1987-12-29 Crossley Robert B Multifunctional behavioral modification device for snoring, bruxism, and apnea
US5522382A (en) * 1987-06-26 1996-06-04 Rescare Limited Device and method for treating obstructed breathing having a delay/ramp feature
US4982738A (en) * 1988-11-30 1991-01-08 Dr. Madaus Gmbh Diagnostic apnea monitor system
US5134995A (en) * 1989-05-19 1992-08-04 Puritan-Bennett Corporation Inspiratory airway pressure system with admittance determining apparatus and method
US5058600A (en) * 1990-01-08 1991-10-22 Center For Innovative Technology Graphical readout of laryngotracheal spectra and airway monitor
US5265624A (en) * 1990-09-06 1993-11-30 Edentec Stimulation collar
US5309922A (en) * 1992-09-21 1994-05-10 Center For Innovative Technology Respiratory sound analyzer for use in high noise environments
US5295490A (en) * 1993-01-21 1994-03-22 Dodakian Wayne S Self-contained apnea monitor
US5738102A (en) * 1994-03-31 1998-04-14 Lemelson; Jerome H. Patient monitoring system
US5671733A (en) * 1994-04-21 1997-09-30 Snap Laboratories, L.L.C. Method of analyzing sleep disorders
US5782240A (en) * 1994-12-22 1998-07-21 Snap Laboratories, L.L.C. Method of classifying respiratory sounds
AUPN304895A0 (en) * 1995-05-19 1995-06-15 Somed Pty Limited Device for detecting and recording snoring
US6168568B1 (en) * 1996-10-04 2001-01-02 Karmel Medical Acoustic Technologies Ltd. Phonopneumograph system
US6241683B1 (en) * 1998-02-20 2001-06-05 INSTITUT DE RECHERCHES CLINIQUES DE MONTRéAL (IRCM) Phonospirometry for non-invasive monitoring of respiration
US6290654B1 (en) * 1998-10-08 2001-09-18 Sleep Solutions, Inc. Obstructive sleep apnea detection apparatus and method using pattern recognition
US6139505A (en) * 1998-10-14 2000-10-31 Murphy; Raymond L. H. Method and apparatus for displaying lung sounds and performing diagnosis based on lung sound analysis
US6935335B1 (en) * 2000-08-17 2005-08-30 Ilife Systems, Inc. System and method for treating obstructive sleep apnea
US6666830B1 (en) * 2000-08-17 2003-12-23 East River Ventures, Lp System and method for detecting the onset of an obstructive sleep apnea event

Also Published As

Publication number Publication date
US7819823B2 (en) 2010-10-26
WO2002013697A1 (en) 2002-02-21
TW579290B (en) 2004-03-11
US6666830B1 (en) 2003-12-23
US20040225226A1 (en) 2004-11-11
AR030367A1 (en) 2003-08-20
AU2001287193A1 (en) 2002-02-25

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