WO2002016903A3 - Microfluidic device and method with trapping of sample in carities having lids that can be opened or closed - Google Patents

Microfluidic device and method with trapping of sample in carities having lids that can be opened or closed Download PDF

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Publication number
WO2002016903A3
WO2002016903A3 PCT/SE2001/001798 SE0101798W WO0216903A3 WO 2002016903 A3 WO2002016903 A3 WO 2002016903A3 SE 0101798 W SE0101798 W SE 0101798W WO 0216903 A3 WO0216903 A3 WO 0216903A3
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WO
WIPO (PCT)
Prior art keywords
sample
carities
lids
trapping
opened
Prior art date
Application number
PCT/SE2001/001798
Other languages
French (fr)
Other versions
WO2002016903A2 (en
Inventor
David Storek
Niklaus Schneeberger
Britta Ottosson
Anatol Krozer
Robert P Otillar
Original Assignee
Imego Ab
David Storek
Niklaus Schneeberger
Britta Ottosson
Anatol Krozer
Robert P Otillar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0002990A external-priority patent/SE0002990L/en
Application filed by Imego Ab, David Storek, Niklaus Schneeberger, Britta Ottosson, Anatol Krozer, Robert P Otillar filed Critical Imego Ab
Priority to JP2002521950A priority Critical patent/JP2004507731A/en
Priority to EP01961525A priority patent/EP1311854A2/en
Priority to AU2001282785A priority patent/AU2001282785A1/en
Publication of WO2002016903A2 publication Critical patent/WO2002016903A2/en
Publication of WO2002016903A3 publication Critical patent/WO2002016903A3/en
Priority to US10/248,847 priority patent/US7431887B2/en

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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
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    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
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    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Abstract

The present invention relates to a sample preparing arrangement (10) submergible in a liquid medium, comprising a carrier structure (11), at least one cavity (12) in said carrier, in communication with said cavity an arrangement (13) for controllable generation of a magnetic filed through influence of a control signal. The sample preparing arrangement comprises a magnetic covering structure (4) for covering/uncovering said cavity in operative interaction with said magnetic field.
PCT/SE2001/001798 2000-08-23 2001-08-23 Microfluidic device and method with trapping of sample in carities having lids that can be opened or closed WO2002016903A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2002521950A JP2004507731A (en) 2000-08-23 2001-08-23 Microfluidic device and method for capturing a sample in a recess with a lid that can be opened and closed
EP01961525A EP1311854A2 (en) 2000-08-23 2001-08-23 Microfuidic device and method with trapping of sample in carities having lids that can be opened or closed
AU2001282785A AU2001282785A1 (en) 2000-08-23 2001-08-23 A sample collecting arrangement and a method
US10/248,847 US7431887B2 (en) 2000-08-24 2003-02-24 Microfluidic device and method with trapping of sample in cavities having lids that can be opened or closed

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE0002990A SE0002990L (en) 2000-08-23 2000-08-23 An arrangement for sample preparation and a method for such an arrangement
SE0002990-0 2000-08-23
US22801500P 2000-08-24 2000-08-24
US60/228,015 2000-08-24

Related Child Applications (1)

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WO2002016903A2 WO2002016903A2 (en) 2002-02-28
WO2002016903A3 true WO2002016903A3 (en) 2002-05-30

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PCT/SE2001/001799 WO2002016904A2 (en) 2000-08-23 2001-08-23 Microfluidic device and method with transport of magnetic particles into and out of wells
PCT/SE2001/001798 WO2002016903A2 (en) 2000-08-23 2001-08-23 Microfluidic device and method with trapping of sample in carities having lids that can be opened or closed

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EP (2) EP1340082A2 (en)
JP (2) JP2004507731A (en)
AU (2) AU2001282786A1 (en)
WO (2) WO2002016904A2 (en)

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JP2004507731A (en) 2004-03-11
JP2004507732A (en) 2004-03-11
US7351592B2 (en) 2008-04-01
AU2001282785A1 (en) 2002-03-04
WO2002016904A3 (en) 2002-05-23
US20040166577A1 (en) 2004-08-26
EP1311854A2 (en) 2003-05-21
WO2002016903A2 (en) 2002-02-28
EP1340082A2 (en) 2003-09-03
AU2001282786A1 (en) 2002-03-04

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