WO2002026939A3 - Microfabrication of membranes for the growth of cells - Google Patents

Microfabrication of membranes for the growth of cells Download PDF

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Publication number
WO2002026939A3
WO2002026939A3 PCT/US2001/029846 US0129846W WO0226939A3 WO 2002026939 A3 WO2002026939 A3 WO 2002026939A3 US 0129846 W US0129846 W US 0129846W WO 0226939 A3 WO0226939 A3 WO 0226939A3
Authority
WO
WIPO (PCT)
Prior art keywords
cells
microfabrication
membranes
growth
present
Prior art date
Application number
PCT/US2001/029846
Other languages
French (fr)
Other versions
WO2002026939A2 (en
Inventor
Brenda Russell
Tejal A Desai
Luke Henley
Original Assignee
Univ Illinois
Brenda Russell
Tejal A Desai
Luke Henley
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Illinois, Brenda Russell, Tejal A Desai, Luke Henley filed Critical Univ Illinois
Priority to AU2001294671A priority Critical patent/AU2001294671A1/en
Publication of WO2002026939A2 publication Critical patent/WO2002026939A2/en
Publication of WO2002026939A3 publication Critical patent/WO2002026939A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657—Cardiomyocytes; Heart cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2535/00—Supports or coatings for cell culture characterised by topography
    • C12N2535/10—Patterned coating

Abstract

The present invention provides a novel substrate for use in growing cells and for the study of mechanobiology. The membrane of the present invention comprises appropriate microtopography and surface chemical modifications to facilitate the production of adherent and oriented cells that phenotypically resemble cells in vivo.
PCT/US2001/029846 2000-09-25 2001-09-24 Microfabrication of membranes for the growth of cells WO2002026939A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001294671A AU2001294671A1 (en) 2000-09-25 2001-09-24 Microfabrication of membranes for the growth of cells

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23509400P 2000-09-25 2000-09-25
US60/235,094 2000-09-25

Publications (2)

Publication Number Publication Date
WO2002026939A2 WO2002026939A2 (en) 2002-04-04
WO2002026939A3 true WO2002026939A3 (en) 2002-08-15

Family

ID=22884080

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/029846 WO2002026939A2 (en) 2000-09-25 2001-09-24 Microfabrication of membranes for the growth of cells

Country Status (3)

Country Link
US (2) US6942873B2 (en)
AU (1) AU2001294671A1 (en)
WO (1) WO2002026939A2 (en)

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US20120129209A1 (en) * 2009-03-19 2012-05-24 The Regents Of The University Of California Aligning cells on wrinkled surface
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Also Published As

Publication number Publication date
US20020081726A1 (en) 2002-06-27
US7695967B1 (en) 2010-04-13
WO2002026939A2 (en) 2002-04-04
AU2001294671A1 (en) 2002-04-08
US6942873B2 (en) 2005-09-13

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