WO2002043564A3 - Systems and methods for making non-invasive physiological assessments - Google Patents

Systems and methods for making non-invasive physiological assessments Download PDF

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Publication number
WO2002043564A3
WO2002043564A3 PCT/US2001/044433 US0144433W WO0243564A3 WO 2002043564 A3 WO2002043564 A3 WO 2002043564A3 US 0144433 W US0144433 W US 0144433W WO 0243564 A3 WO0243564 A3 WO 0243564A3
Authority
WO
WIPO (PCT)
Prior art keywords
systems
methods
tissue
properties
monitoring
Prior art date
Application number
PCT/US2001/044433
Other languages
French (fr)
Other versions
WO2002043564A2 (en
WO2002043564A9 (en
Inventor
Pierre Mourad
Michel Kliot
Ali Mesiwala
Rex Patterson
Jeffrey G Jarvik
Original Assignee
Allez Physionix Ltd
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allez Physionix Ltd, Univ Washington filed Critical Allez Physionix Ltd
Priority to EP01987113A priority Critical patent/EP1345527A4/en
Priority to AU2002239360A priority patent/AU2002239360A1/en
Priority to JP2002545551A priority patent/JP2004520870A/en
Priority to CA2428872A priority patent/CA2428872C/en
Publication of WO2002043564A2 publication Critical patent/WO2002043564A2/en
Publication of WO2002043564A3 publication Critical patent/WO2002043564A3/en
Publication of WO2002043564A9 publication Critical patent/WO2002043564A9/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/415—Evaluating particular organs or parts of the immune or lymphatic systems the glands, e.g. tonsils, adenoids or thymus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0048—Detecting, measuring or recording by applying mechanical forces or stimuli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/4064—Evaluating the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/418—Evaluating particular organs or parts of the immune or lymphatic systems lymph vessels, ducts or nodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4824—Touch or pain perception evaluation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
    • A61B8/0808—Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of the brain
    • A61B8/0816—Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of the brain using echo-encephalography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/485—Diagnostic techniques involving measuring strain or elastic properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/03—Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs
    • A61B5/031—Intracranial pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/04—Measuring blood pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/488—Diagnostic techniques involving Doppler signals

Abstract

Systems and methods for assessment of tissue properties, noninvasively, by acquiring data relating to at least one aspect of intrinsic and/or induced tissue displacement, or associated biological responses, are provided. Data relating to tissue displacement and associated biological changes may be acquired by detecting acoustic properties of tissue using ultrasound interrogation pulses, preferably in a scatter or Doppler detection mode. Based on this data, tissue properties are assessed, characterized and monitored. Specific applications for systems and methods of the present invention include non-invasive assessment and monitoring of intracranial pressure (ICP), arterial blood pressure (ABP), CNS autoregulation status, vasospasm, stroke, local edema, infection and vasculitus, as well as diagnosis and monitoring of diseases and conditions that are characterized by physical changes in tissue properties. Methods and systems for localizing physiological condition(s) and/or biological response(s), such as pain, by targeting and selectively palpating tissues using the application of acoustic radiation forces are also provided.
PCT/US2001/044433 2000-11-28 2001-11-28 Systems and methods for making non-invasive physiological assessments WO2002043564A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP01987113A EP1345527A4 (en) 2000-11-28 2001-11-28 Systems and methods for making non-invasive physiological assessments
AU2002239360A AU2002239360A1 (en) 2000-11-28 2001-11-28 Systems and methods for making non-invasive physiological assessments
JP2002545551A JP2004520870A (en) 2000-11-28 2001-11-28 Non-invasive physiological evaluation system and method
CA2428872A CA2428872C (en) 2000-11-28 2001-11-28 Systems and methods for making non-invasive physiological assessments

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25395900P 2000-11-28 2000-11-28
US60/253,959 2000-11-28

Publications (3)

Publication Number Publication Date
WO2002043564A2 WO2002043564A2 (en) 2002-06-06
WO2002043564A3 true WO2002043564A3 (en) 2003-01-30
WO2002043564A9 WO2002043564A9 (en) 2003-08-07

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/044433 WO2002043564A2 (en) 2000-11-28 2001-11-28 Systems and methods for making non-invasive physiological assessments

Country Status (6)

Country Link
US (1) US6875176B2 (en)
EP (1) EP1345527A4 (en)
JP (2) JP2004520870A (en)
AU (1) AU2002239360A1 (en)
CA (1) CA2428872C (en)
WO (1) WO2002043564A2 (en)

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