WO2002060517A3 - Medicament respiratory delivery device and method - Google Patents

Medicament respiratory delivery device and method Download PDF

Info

Publication number
WO2002060517A3
WO2002060517A3 PCT/US2002/000578 US0200578W WO02060517A3 WO 2002060517 A3 WO2002060517 A3 WO 2002060517A3 US 0200578 W US0200578 W US 0200578W WO 02060517 A3 WO02060517 A3 WO 02060517A3
Authority
WO
WIPO (PCT)
Prior art keywords
delivery device
chamber
medicament
outlet
valve
Prior art date
Application number
PCT/US2002/000578
Other languages
French (fr)
Other versions
WO2002060517A2 (en
Inventor
Robert A Casper
John M Snow
David L Gardner
Vincent J Sullivan
Anjana Bhuta Wills
Lawrence A Monahan
Christopher J Knors
Original Assignee
Becton Dickinson Co
Robert A Casper
John M Snow
David L Gardner
Vincent J Sullivan
Anjana Bhuta Wills
Lawrence A Monahan
Christopher J Knors
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/758,776 external-priority patent/US6722364B2/en
Application filed by Becton Dickinson Co, Robert A Casper, John M Snow, David L Gardner, Vincent J Sullivan, Anjana Bhuta Wills, Lawrence A Monahan, Christopher J Knors filed Critical Becton Dickinson Co
Priority to EP02718817A priority Critical patent/EP1349599B1/en
Priority to JP2002560708A priority patent/JP4216600B2/en
Priority to DE60212797T priority patent/DE60212797T2/en
Publication of WO2002060517A2 publication Critical patent/WO2002060517A2/en
Publication of WO2002060517A3 publication Critical patent/WO2002060517A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/06—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump
    • B05B11/061—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump characterised by the means producing the gas or vapour pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/02—Sprayers or atomisers specially adapted for therapeutic purposes operated by air or other gas pressure applied to the liquid or other product to be sprayed or atomised
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0031—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up by bursting or breaking the package, i.e. without cutting or piercing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/0081—Locking means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01—Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/06—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump
    • B05B11/062—Gas or vapour producing the flow, e.g. from a compressible bulb or air pump designed for spraying particulate material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/07—General characteristics of the apparatus having air pumping means
    • A61M2205/071—General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073—Syringe, piston type

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nozzles (AREA)

Abstract

A medicament respiratory delivery device including a housing having a chamber including coaxially aligned inlet and outlet, a medicament cartridge located within the chamber having a passage therethrough and membranes sealing the passage having a burst pressure of less than 10 atmospheres, a manually actuatable fluid delivery device having an outlet in fluid communication with the chamber and a manually actuated valve located between the outlet of the fluid delivery device and the chamber inlet for delivery of fluid under pressure to the valve. The medicament respiratory delivery device of this invention may be utilized to deliver a controlled unit dose of an aerosolizable medicament on demand by first pressurizing a pressure chamber in the pressure delivery device upstream of the valve, then opening the valve to open the membranes and express the medicament through the chamber outlet.
PCT/US2002/000578 2001-01-12 2002-01-09 Medicament respiratory delivery device and method WO2002060517A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP02718817A EP1349599B1 (en) 2001-01-12 2002-01-09 Medicament respiratory delivery device and method
JP2002560708A JP4216600B2 (en) 2001-01-12 2002-01-09 Device and method for drug delivery to the respiratory tract
DE60212797T DE60212797T2 (en) 2001-01-12 2002-01-09 MEDICAMENT HOLDING DEVICE AND METHOD

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/758,776 2001-01-12
US09/758,776 US6722364B2 (en) 2001-01-12 2001-01-12 Medicament inhalation delivery devices and methods for using the same
US09/950,369 2001-09-10
US09/950,369 US6644309B2 (en) 2001-01-12 2001-09-10 Medicament respiratory delivery device and method

Publications (2)

Publication Number Publication Date
WO2002060517A2 WO2002060517A2 (en) 2002-08-08
WO2002060517A3 true WO2002060517A3 (en) 2002-11-07

Family

ID=27116577

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/000578 WO2002060517A2 (en) 2001-01-12 2002-01-09 Medicament respiratory delivery device and method

Country Status (7)

Country Link
US (2) US6644309B2 (en)
EP (1) EP1349599B1 (en)
JP (1) JP4216600B2 (en)
AT (1) ATE331548T1 (en)
DE (1) DE60212797T2 (en)
ES (1) ES2262793T3 (en)
WO (1) WO2002060517A2 (en)

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JP4216600B2 (en) 2009-01-28
ES2262793T3 (en) 2006-12-01
DE60212797D1 (en) 2006-08-10
EP1349599A2 (en) 2003-10-08
JP2004522519A (en) 2004-07-29
EP1349599B1 (en) 2006-06-28
US20020092520A1 (en) 2002-07-18
US7051734B2 (en) 2006-05-30
US6644309B2 (en) 2003-11-11
ATE331548T1 (en) 2006-07-15
US20040079363A1 (en) 2004-04-29
WO2002060517A2 (en) 2002-08-08
DE60212797T2 (en) 2007-06-21

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