WO2002066151A3 - Apparatus and methods for parallel processing of multiple reaction mixtures - Google Patents
Apparatus and methods for parallel processing of multiple reaction mixtures Download PDFInfo
- Publication number
- WO2002066151A3 WO2002066151A3 PCT/US2002/002617 US0202617W WO02066151A3 WO 2002066151 A3 WO2002066151 A3 WO 2002066151A3 US 0202617 W US0202617 W US 0202617W WO 02066151 A3 WO02066151 A3 WO 02066151A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cannula
- reactor
- reaction mixtures
- methods
- parallel processing
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00281—Individual reactor vessels
- B01J2219/00283—Reactor vessels with top opening
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00308—Reactor vessels in a multiple arrangement interchangeably mounted in racks or blocks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00331—Details of the reactor vessels
- B01J2219/00333—Closures attached to the reactor vessels
- B01J2219/00335—Septa
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00331—Details of the reactor vessels
- B01J2219/00333—Closures attached to the reactor vessels
- B01J2219/00337—Valves
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00373—Hollow needles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00418—Means for dispensing and evacuation of reagents using pressure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00477—Means for pressurising the reaction vessels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00479—Means for mixing reactants or products in the reaction vessels
- B01J2219/00481—Means for mixing reactants or products in the reaction vessels by the use of moving stirrers within the reaction vessels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00495—Means for heating or cooling the reaction vessels
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00601—High-pressure processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00686—Automatic
- B01J2219/00689—Automatic using computers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00686—Automatic
- B01J2219/00691—Automatic using robots
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/14—Libraries containing macromolecular compounds and not covered by groups C40B40/06 - C40B40/12
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25875—Gaseous sample or with change of physical state
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Devices And Processes Conducted In The Presence Of Fluids And Solid Particles (AREA)
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26448901P | 2001-01-26 | 2001-01-26 | |
US60/264,489 | 2001-01-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002066151A2 WO2002066151A2 (en) | 2002-08-29 |
WO2002066151A3 true WO2002066151A3 (en) | 2003-02-27 |
Family
ID=23006292
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/002617 WO2002066151A2 (en) | 2001-01-26 | 2002-01-28 | Apparatus and methods for parallel processing of multiple reaction mixtures |
Country Status (2)
Country | Link |
---|---|
US (2) | US7335513B2 (en) |
WO (1) | WO2002066151A2 (en) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7288228B2 (en) * | 2002-02-12 | 2007-10-30 | Gilson, Inc. | Sample injection system |
US7160513B2 (en) * | 2002-12-20 | 2007-01-09 | Symyx Technologies, Inc. | Batch reactor with injection system |
DE60305912T2 (en) * | 2003-08-05 | 2007-02-01 | Lasag Ag | Method of making a medical needle |
US7789872B2 (en) * | 2005-03-23 | 2010-09-07 | Shippert Ronald D | Tissue transplantation method and apparatus |
US7780649B2 (en) * | 2005-03-23 | 2010-08-24 | Shippert Ronald D | Tissue transplantation method and apparatus |
US8622997B2 (en) * | 2005-03-23 | 2014-01-07 | Ronald D. Shippert | Tissue transfer method and apparatus |
US9581942B1 (en) | 2005-03-23 | 2017-02-28 | Shippert Enterprises, Llc | Tissue transfer method and apparatus |
US8062286B2 (en) * | 2005-03-23 | 2011-11-22 | Shippert Ronald D | Tissue transplantation method and apparatus |
US7794449B2 (en) | 2005-03-23 | 2010-09-14 | Shippert Ronald D | Tissue transplantation method and apparatus |
US20080286170A1 (en) * | 2007-05-14 | 2008-11-20 | Symyx Technologies, Inc. | Parallel batch reactor |
US7655191B2 (en) * | 2007-05-14 | 2010-02-02 | Symyx Solutions, Inc. | Methods for chemical reactions in a parallel batch reactor |
US7960313B2 (en) * | 2007-06-14 | 2011-06-14 | Intermolecular, Inc. | Combinatorial processing including stirring |
US7785172B2 (en) * | 2007-08-14 | 2010-08-31 | Intermolecular, Inc. | Combinatorial processing including rotation and movement within a region |
CA2702925C (en) | 2007-10-17 | 2016-09-20 | Aushon Biosystems | Continual flow pin washer |
US9044774B2 (en) * | 2007-12-18 | 2015-06-02 | Intermolecular, Inc. | Vented combinatorial processing cell |
JP2009222474A (en) * | 2008-03-14 | 2009-10-01 | Panasonic Corp | Micro-liquid transfer apparatus and micro-mliquid transfer method |
US9016233B1 (en) * | 2008-04-23 | 2015-04-28 | Intermolecular, Inc. | Volume combinatorial processing chamber |
WO2011140668A1 (en) * | 2010-05-12 | 2011-11-17 | Eth Zurich | 3d nanocrystals and manufacturing methods |
US8887770B1 (en) | 2011-03-17 | 2014-11-18 | Ronald D. Shippert | Vessel fill control method and apparatus |
WO2013148669A1 (en) | 2012-03-26 | 2013-10-03 | Freeslate, Inc. | Parallel reactor systems and methods for preparing materials |
US10492876B2 (en) | 2012-09-17 | 2019-12-03 | Omniguide, Inc. | Devices and methods for laser surgery |
US9468709B2 (en) | 2012-11-12 | 2016-10-18 | Shippert Enterprises, Llc | Syringe fill method and apparatus |
US9915591B2 (en) | 2013-04-30 | 2018-03-13 | Unchained Labs | Methods for sampling from non-atmospheric vessels in a parallel reactor system |
US10772997B2 (en) | 2014-05-15 | 2020-09-15 | Ronald D. Shippert | Tissue parcelization method and apparatus |
EP3322310B1 (en) * | 2015-07-13 | 2021-09-29 | Philip Morris Products S.A. | Producing an aerosol-forming composition |
WO2020014416A1 (en) * | 2018-07-13 | 2020-01-16 | Baker Hughes, A Ge Company, Llc | Method and system for demulsifier testing |
Citations (8)
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US3683977A (en) * | 1969-05-21 | 1972-08-15 | Beckman Instruments Ltd | Liquid dispensing apparatus |
US5380495A (en) * | 1993-08-27 | 1995-01-10 | Chang; Heng-Wei | Solid phase peptide synthesizer |
WO1996033805A2 (en) * | 1995-04-17 | 1996-10-31 | Ontogen Corporation | Pipetting needle and rinse station therefor for fluid transfer under inert atmosphere operations |
DE19749557A1 (en) * | 1997-11-10 | 1999-05-12 | Jung Guenther Prof Dr | Appts for parallel chemical reactions |
WO1999051980A2 (en) * | 1998-04-03 | 1999-10-14 | Symyx Technologies | Rapid characterization of polymers |
US5976470A (en) * | 1998-05-29 | 1999-11-02 | Ontogen Corporation | Sample wash station assembly |
WO2000009255A2 (en) * | 1998-08-13 | 2000-02-24 | Symyx Technologies | Parallel reactor with internal sensing and method of using same |
WO2001036087A1 (en) * | 1999-11-17 | 2001-05-25 | Dsm N.V. | Examining chemical reactions |
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US2217602A (en) | 1938-05-12 | 1940-10-08 | Macgregor Instr Company | Hypodermic needle |
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IT998674B (en) | 1973-09-28 | 1976-02-20 | Orinospital Spa | PERFECTED SUCTION AND INFUSION NEEDLE |
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-
2002
- 2002-01-28 WO PCT/US2002/002617 patent/WO2002066151A2/en not_active Application Discontinuation
- 2002-01-28 US US10/060,075 patent/US7335513B2/en active Active
-
2007
- 2007-12-20 US US11/961,326 patent/US7858049B2/en not_active Expired - Lifetime
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3683977A (en) * | 1969-05-21 | 1972-08-15 | Beckman Instruments Ltd | Liquid dispensing apparatus |
US5380495A (en) * | 1993-08-27 | 1995-01-10 | Chang; Heng-Wei | Solid phase peptide synthesizer |
WO1996033805A2 (en) * | 1995-04-17 | 1996-10-31 | Ontogen Corporation | Pipetting needle and rinse station therefor for fluid transfer under inert atmosphere operations |
DE19749557A1 (en) * | 1997-11-10 | 1999-05-12 | Jung Guenther Prof Dr | Appts for parallel chemical reactions |
WO1999051980A2 (en) * | 1998-04-03 | 1999-10-14 | Symyx Technologies | Rapid characterization of polymers |
US5976470A (en) * | 1998-05-29 | 1999-11-02 | Ontogen Corporation | Sample wash station assembly |
WO2000009255A2 (en) * | 1998-08-13 | 2000-02-24 | Symyx Technologies | Parallel reactor with internal sensing and method of using same |
WO2001036087A1 (en) * | 1999-11-17 | 2001-05-25 | Dsm N.V. | Examining chemical reactions |
Non-Patent Citations (1)
Title |
---|
CORK D G ET AL: "FURTHER DEVELOPMENT OF A VERSATILE MICROSALE AUTOMATED WORKSTATION FOR PARALLEL ADAPTIVE EXPERIMENTATION", LABORATORY ROBOTICS AND AUTOMATION, VCH PUBLISHERS, NEW YORK, US, vol. 11, no. 4, 1999, pages 217 - 223, XP000923084, ISSN: 0895-7533 * |
Also Published As
Publication number | Publication date |
---|---|
US7335513B2 (en) | 2008-02-26 |
WO2002066151A2 (en) | 2002-08-29 |
US7858049B2 (en) | 2010-12-28 |
US20080138260A1 (en) | 2008-06-12 |
US20020106813A1 (en) | 2002-08-08 |
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