WO2002078830A3 - Granulation method and device using focused acoustic energy - Google Patents

Granulation method and device using focused acoustic energy Download PDF

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Publication number
WO2002078830A3
WO2002078830A3 PCT/US2002/010384 US0210384W WO02078830A3 WO 2002078830 A3 WO2002078830 A3 WO 2002078830A3 US 0210384 W US0210384 W US 0210384W WO 02078830 A3 WO02078830 A3 WO 02078830A3
Authority
WO
WIPO (PCT)
Prior art keywords
acoustic energy
focused acoustic
solution
granulation method
droplet
Prior art date
Application number
PCT/US2002/010384
Other languages
French (fr)
Other versions
WO2002078830A2 (en
Inventor
David Soong-Hua Lee
Original Assignee
Picoliter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Picoliter Inc filed Critical Picoliter Inc
Priority to JP2002577087A priority Critical patent/JP2005502445A/en
Priority to AU2002311798A priority patent/AU2002311798A1/en
Priority to EP02739126A priority patent/EP1385613B1/en
Priority to AT02739126T priority patent/ATE520454T1/en
Publication of WO2002078830A2 publication Critical patent/WO2002078830A2/en
Publication of WO2002078830A3 publication Critical patent/WO2002078830A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops

Abstract

A method and device for generating solid particles using focused acoustic energy are provided. A solution of a compound of interest is provided in a solvent, which may be an aqueous fluid, a nonaqueous fluid, or a supercritical fluid. Focused acoustic energy is used to eject a droplet of the solution, which is then directed into or through an antisolvent that upon admixture with the solution droplet causes the compounds in the droplet to precipitate. In a preferred embodiment, the solvent is an aqueous or organic liquid, and the antisolvent is a supercritical fluid.
PCT/US2002/010384 2001-03-30 2002-04-01 Granulation method and device using focused acoustic energy WO2002078830A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2002577087A JP2005502445A (en) 2001-03-30 2002-04-01 Concentrated acoustic energy in the production of solid particles.
AU2002311798A AU2002311798A1 (en) 2001-03-30 2002-04-01 Granulation method and device using focused acoustic energy
EP02739126A EP1385613B1 (en) 2001-03-30 2002-04-01 Focused acoustic energy in the generation of solid particles
AT02739126T ATE520454T1 (en) 2001-03-30 2002-04-01 FOCUSED SOUND ENERGY IN THE PRODUCTION OF SOLIDS

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/823,890 US6610223B2 (en) 2001-03-30 2001-03-30 Focused acoustic energy in the generation of solid particles
US09/823,890 2001-03-30

Publications (2)

Publication Number Publication Date
WO2002078830A2 WO2002078830A2 (en) 2002-10-10
WO2002078830A3 true WO2002078830A3 (en) 2003-11-27

Family

ID=25240024

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/010384 WO2002078830A2 (en) 2001-03-30 2002-04-01 Granulation method and device using focused acoustic energy

Country Status (6)

Country Link
US (1) US6610223B2 (en)
EP (1) EP1385613B1 (en)
JP (1) JP2005502445A (en)
AT (1) ATE520454T1 (en)
AU (1) AU2002311798A1 (en)
WO (1) WO2002078830A2 (en)

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US6620351B2 (en) * 2000-05-24 2003-09-16 Auburn University Method of forming nanoparticles and microparticles of controllable size using supercritical fluids with enhanced mass transfer
US6746104B2 (en) * 2000-09-25 2004-06-08 Picoliter Inc. Method for generating molecular arrays on porous surfaces
US6642061B2 (en) * 2000-09-25 2003-11-04 Picoliter Inc. Use of immiscible fluids in droplet ejection through application of focused acoustic energy
US6666541B2 (en) * 2000-09-25 2003-12-23 Picoliter Inc. Acoustic ejection of fluids from a plurality of reservoirs
US6849423B2 (en) * 2000-11-29 2005-02-01 Picoliter Inc Focused acoustics for detection and sorting of fluid volumes
US6893836B2 (en) * 2000-11-29 2005-05-17 Picoliter Inc. Spatially directed ejection of cells from a carrier fluid
US6811895B2 (en) * 2001-03-22 2004-11-02 Lumimove, Inc. Illuminated display system and process
CA2473969A1 (en) * 2001-04-30 2002-11-07 Lumimove, Inc. Electroluminescent devices fabricated with encapsulated light emitting polymer particles
US7717544B2 (en) 2004-10-01 2010-05-18 Labcyte Inc. Method for acoustically ejecting a droplet of fluid from a reservoir by an acoustic fluid ejection apparatus
US7354141B2 (en) * 2001-12-04 2008-04-08 Labcyte Inc. Acoustic assessment of characteristics of a fluid relevant to acoustic ejection
US20030101819A1 (en) * 2001-12-04 2003-06-05 Mutz Mitchell W. Acoustic assessment of fluids in a plurality of reservoirs
US7361413B2 (en) * 2002-07-29 2008-04-22 Lumimove, Inc. Electroluminescent device and methods for its production and use
US7029763B2 (en) * 2002-07-29 2006-04-18 Lumimove, Inc. Light-emitting phosphor particles and electroluminescent devices employing same
US6893115B2 (en) * 2002-09-20 2005-05-17 Picoliter Inc. Frequency correction for drop size control
US7070260B2 (en) * 2003-01-09 2006-07-04 Labcyte Inc. Droplet dispensation from a reservoir with reduction in uncontrolled electrostatic charge
KR100603974B1 (en) * 2003-12-05 2006-07-25 김갑식 Method for preparing nano-scale or amorphous particle using solid fat as a solvent
US7446360B2 (en) * 2004-08-09 2008-11-04 Intel Corporation Polymer device with a nanocomposite barrier layer
US20060210443A1 (en) 2005-03-14 2006-09-21 Stearns Richard G Avoidance of bouncing and splashing in droplet-based fluid transport
GB0602637D0 (en) * 2006-02-09 2006-03-22 Glaxo Group Ltd Novel process
AU2007246277A1 (en) * 2006-05-04 2007-11-15 Bio-Synectics Inc. Method for preparing nano-scale particle of active material
CN101542787A (en) 2006-09-25 2009-09-23 德克萨斯州立大学董事会 Cation-substituted spinel oxide and oxyfluoride cathodes for lithium ion batteries
US7753636B2 (en) * 2008-03-25 2010-07-13 Hennig Emmett D Adjustable bale mover spikes
EP2919762A4 (en) * 2012-11-16 2016-07-20 Merck Sharp & Dohme Process for making agglomerates using acoustic mixing technology
US9159999B2 (en) 2013-03-15 2015-10-13 Nano One Materials Corp. Complexometric precursor formulation methodology for industrial production of fine and ultrafine powders and nanopowders for lithium metal oxides for battery applications
GB2516694B (en) * 2013-07-30 2016-09-07 Mexichem Amanco Holding Sa Heat transfer compositions
US9861987B2 (en) * 2014-01-15 2018-01-09 Labcyte Inc. Roughly cylindrical sample containers having multiple reservoirs therein and being adapted for acoustic ejections
GB201501598D0 (en) 2015-01-30 2015-03-18 Mexichem Fluor Sa De Cv Compositions
KR102645443B1 (en) * 2018-12-21 2024-03-11 (주)아모레퍼시픽 Method for manufacturing of cosmetic composition by using resonance frequency

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997031691A1 (en) * 1996-03-01 1997-09-04 The University Of Kansas Methods and apparatus for particle precipitation and coating using near-critical and supercritical antisolvents
WO2000044468A1 (en) * 1999-01-29 2000-08-03 Bristol-Myers Squibb Company Sonic impinging jet crystallization apparatus and process
US20020000681A1 (en) * 2000-05-24 2002-01-03 Gupta Ram B. Method of forming nanoparticles and microparticles of controllable size using supercritical fluids and ultrasound
WO2002013786A2 (en) * 2000-08-15 2002-02-21 Board Of Trustees Of The University Of Illinois Method of forming microparticles
WO2002024325A2 (en) * 2000-09-25 2002-03-28 Picoliter, Inc. Acoustic ejection of fluids from a plurality of reservoirs

Family Cites Families (5)

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Publication number Priority date Publication date Assignee Title
US4308547A (en) 1978-04-13 1981-12-29 Recognition Equipment Incorporated Liquid drop emitter
US5041849A (en) 1989-12-26 1991-08-20 Xerox Corporation Multi-discrete-phase Fresnel acoustic lenses and their application to acoustic ink printing
US6063910A (en) 1991-11-14 2000-05-16 The Trustees Of Princeton University Preparation of protein microparticles by supercritical fluid precipitation
US5874029A (en) 1996-10-09 1999-02-23 The University Of Kansas Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent
GB9828204D0 (en) 1998-12-21 1999-02-17 Smithkline Beecham Plc Process

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997031691A1 (en) * 1996-03-01 1997-09-04 The University Of Kansas Methods and apparatus for particle precipitation and coating using near-critical and supercritical antisolvents
WO2000044468A1 (en) * 1999-01-29 2000-08-03 Bristol-Myers Squibb Company Sonic impinging jet crystallization apparatus and process
US20020000681A1 (en) * 2000-05-24 2002-01-03 Gupta Ram B. Method of forming nanoparticles and microparticles of controllable size using supercritical fluids and ultrasound
WO2002013786A2 (en) * 2000-08-15 2002-02-21 Board Of Trustees Of The University Of Illinois Method of forming microparticles
WO2002024325A2 (en) * 2000-09-25 2002-03-28 Picoliter, Inc. Acoustic ejection of fluids from a plurality of reservoirs

Also Published As

Publication number Publication date
WO2002078830A2 (en) 2002-10-10
ATE520454T1 (en) 2011-09-15
AU2002311798A1 (en) 2002-10-15
EP1385613A2 (en) 2004-02-04
US20020140118A1 (en) 2002-10-03
US6610223B2 (en) 2003-08-26
JP2005502445A (en) 2005-01-27
EP1385613B1 (en) 2011-08-17

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