WO2002096262A3 - Non-alloying core shell nanoparticles - Google Patents

Non-alloying core shell nanoparticles Download PDF

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Publication number
WO2002096262A3
WO2002096262A3 PCT/US2001/050825 US0150825W WO02096262A3 WO 2002096262 A3 WO2002096262 A3 WO 2002096262A3 US 0150825 W US0150825 W US 0150825W WO 02096262 A3 WO02096262 A3 WO 02096262A3
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WO
WIPO (PCT)
Prior art keywords
shell nanoparticles
core shell
core
relates
alloying
Prior art date
Application number
PCT/US2001/050825
Other languages
French (fr)
Other versions
WO2002096262A2 (en
Inventor
Chad A Mirkin
Yunwei Cao
Rongchao Jin
Original Assignee
Univ Northwestern
Chad A Mirkin
Yunwei Cao
Rongchao Jin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Northwestern, Chad A Mirkin, Yunwei Cao, Rongchao Jin filed Critical Univ Northwestern
Priority to AU2002239726A priority Critical patent/AU2002239726A1/en
Priority to US10/153,483 priority patent/US7147687B2/en
Priority to EP02775688A priority patent/EP1392872B1/en
Priority to DE60218840T priority patent/DE60218840T2/en
Priority to PCT/US2002/016382 priority patent/WO2003008539A2/en
Priority to AU2002341539A priority patent/AU2002341539B2/en
Priority to AT02775688T priority patent/ATE356826T1/en
Priority to JP2003514082A priority patent/JP3885054B2/en
Publication of WO2002096262A2 publication Critical patent/WO2002096262A2/en
Publication of WO2002096262A3 publication Critical patent/WO2002096262A3/en
Priority to US11/636,392 priority patent/US20070190551A1/en

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    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6923—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being an inorganic particle, e.g. ceramic particles, silica particles, ferrite or synsorb
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Abstract

The present invention relates composite core/shell nanoparticles and a two-step method for their preparation. The present invention further relates to biomolecule-core/shell nanoparticle conjugates and methods for their preparation. The invention also relates to methods of detection of biomolecules comprising the biomolecule or specific binding substance-core/shell nanoparticle conjugates.
PCT/US2001/050825 2001-05-25 2001-12-28 Non-alloying core shell nanoparticles WO2002096262A2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
AU2002239726A AU2002239726A1 (en) 2001-05-25 2001-12-28 Non-alloying core shell nanoparticles
US10/153,483 US7147687B2 (en) 2001-05-25 2002-05-22 Non-alloying core shell nanoparticles
EP02775688A EP1392872B1 (en) 2001-05-25 2002-05-22 Non-alloying core shell nanoparticles
DE60218840T DE60218840T2 (en) 2001-05-25 2002-05-22 Non-alloyed core-shell nanoparticles
PCT/US2002/016382 WO2003008539A2 (en) 2001-05-25 2002-05-22 Non-alloying core shell nanoparticles
AU2002341539A AU2002341539B2 (en) 2001-05-25 2002-05-22 Non-alloying core shell nanoparticles
AT02775688T ATE356826T1 (en) 2001-05-25 2002-05-22 NON-ALLOYING CORE-SHELL NANOPARTICLES
JP2003514082A JP3885054B2 (en) 2001-05-25 2002-05-22 Non-alloy core-shell nanoparticles
US11/636,392 US20070190551A1 (en) 2001-05-25 2006-12-08 Non-alloying core shell nanoparticles

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29386101P 2001-05-25 2001-05-25
US60/293,861 2001-05-25

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