WO2003037407A1 - Transdermal transport device with suction - Google Patents
Transdermal transport device with suction Download PDFInfo
- Publication number
- WO2003037407A1 WO2003037407A1 PCT/US2002/033830 US0233830W WO03037407A1 WO 2003037407 A1 WO2003037407 A1 WO 2003037407A1 US 0233830 W US0233830 W US 0233830W WO 03037407 A1 WO03037407 A1 WO 03037407A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- skin
- microneedles
- reservoir
- transport device
- needles
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/155—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by gas introduced into the reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M2005/1401—Functional features
- A61M2005/1405—Patient controlled analgesia [PCA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M2005/14204—Pressure infusion, e.g. using pumps with gas-producing electrochemical cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
- A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M2005/14268—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body with a reusable and a disposable component
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
- A61M2005/1581—Right-angle needle-type devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0023—Drug applicators using microneedles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0038—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0266—Shape memory materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/65—Impedance, e.g. conductivity, capacity
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
- A61M5/425—Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means
Definitions
- FIG. 9A is a graph of the magnitude of the impedance measured by the impedance sensor of FIG. 8 A versus frequency.
- FIG. 9B is a graph of the impedance versus the penetration depth.
- FIG. 11 is a cross-sectional view of yet another alternative embodiment of the transdennal transport device.
- the microneedles 14 have an inner diameter of about 10 ⁇ m to 100 ⁇ m, an outer diameter of 30 ⁇ m to 250 ⁇ m, and a length of approximately 5 mm to 10 mm. h the above illustrated embodiment, each of the microneedles has an inner diameter of 54 ⁇ m, and an outer diameter of 108 ⁇ m. Other embodiments use microneedles with an inner diameter of about 100 ⁇ m and outer diameter of about 175 ⁇ m.
- the reservoir 46 is easily loaded with a substance to be delivered. Loading can occur before or after association of the reservoir 46 with the microneedles 14.
- the formulation can be one or more non-liquid drugs (for example, that have been dehydrated) that may be preloaded into the reservoir and then reconstituted before deliveiy.
- the inside of the reservoir 46 is coated with a material prior to assembly of the reservoir.
- the coating can have one or more purposes, including, but not limited to, aiding flow so that the substance exiting or entering the reservoir moves smoothly and/or does not leave behind droplets, serving as a reactant used for detecting the presence or absence of a particular material in the fluid, and/or serving as a preservative.
- the device 10 includes electrical sensors, such as the impedance sensor 32 which detects penetration of the stratum comeum. That is, the sensor 32 signals when the desired insertion of the microneedles 12 have been achieved.
- the determination of the location of the microneedle tip(s) within or through the stratum comeum allows for delivery of a complete, predetermined dose to the patient at a location amenable for absorption by the patient's body. This is accomplished by measuring impedance of the tissue as the microneedles proceed through it. As the stratum comeum creates a high level of impedance, and the tissue beyond the stratum, comeum only provides a relatively low level of impedance, impedance is monitored to detennine when the microneedles have passed through the stratum comeum.
- the top portion 94 of the graph illustrates the measured impedance of pig skin ' over a frequency range before a microneedle penetrates the stratum comeum and the bottom portion 96 represents the measured impedance after the microneedle has penetrated the stratum comeum.
- the difference between the two portions 94 and 96 of the graph can be over three orders of magnitude.
- FIG. 9B there is shown a plot of impedance versus the perpendicular depth into the skin, which clearly illustrate that the penetration into the skin produces smaller impedances.
Abstract
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003539746A JP4610193B2 (en) | 2001-10-26 | 2002-10-22 | Percutaneous transport device having suction mechanism |
EP02784221A EP1448253B1 (en) | 2001-10-26 | 2002-10-22 | Transdermal transport device with suction |
CA2464670A CA2464670C (en) | 2001-10-26 | 2002-10-22 | Transdermal transport device with suction |
AU2002348009A AU2002348009B9 (en) | 2001-10-26 | 2002-10-22 | Transdermal transport device with suction |
DE60230795T DE60230795D1 (en) | 2001-10-26 | 2002-10-22 | TRANSDERMAL TRANSPORT DEVICE WITH INTAKE |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33842501P | 2001-10-26 | 2001-10-26 | |
US60/338,425 | 2001-10-26 | ||
US39948902P | 2002-07-29 | 2002-07-29 | |
US60/399,489 | 2002-07-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003037407A1 true WO2003037407A1 (en) | 2003-05-08 |
Family
ID=26991185
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/033544 WO2003037403A1 (en) | 2001-10-26 | 2002-10-18 | Microneedle transport device |
PCT/US2002/033794 WO2003037404A1 (en) | 2001-10-26 | 2002-10-21 | Microneedle transdermal transport device |
PCT/US2002/033829 WO2003037406A2 (en) | 2001-10-26 | 2002-10-22 | Transdermal transport device with an electrolytic actuator |
PCT/US2002/033823 WO2003037405A1 (en) | 2001-10-26 | 2002-10-22 | Impedance sensor |
PCT/US2002/033830 WO2003037407A1 (en) | 2001-10-26 | 2002-10-22 | Transdermal transport device with suction |
Family Applications Before (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/033544 WO2003037403A1 (en) | 2001-10-26 | 2002-10-18 | Microneedle transport device |
PCT/US2002/033794 WO2003037404A1 (en) | 2001-10-26 | 2002-10-21 | Microneedle transdermal transport device |
PCT/US2002/033829 WO2003037406A2 (en) | 2001-10-26 | 2002-10-22 | Transdermal transport device with an electrolytic actuator |
PCT/US2002/033823 WO2003037405A1 (en) | 2001-10-26 | 2002-10-22 | Impedance sensor |
Country Status (8)
Country | Link |
---|---|
US (7) | US7429258B2 (en) |
EP (5) | EP1439871B1 (en) |
JP (10) | JP2005525141A (en) |
AT (3) | ATE420680T1 (en) |
AU (3) | AU2002353840B2 (en) |
CA (5) | CA2464483C (en) |
DE (3) | DE60230896D1 (en) |
WO (5) | WO2003037403A1 (en) |
Cited By (13)
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---|---|---|---|---|
EP2158908A1 (en) * | 2007-06-21 | 2010-03-03 | Fujimoto Co., Ltd. | Composition for transdermal or transmucosal administration |
US8740838B2 (en) | 2010-10-07 | 2014-06-03 | Massachusetts Institute Of Technology | Injection methods using a servo-controlled needle-free injector |
US8821434B2 (en) | 2010-10-07 | 2014-09-02 | Massachusetts Institute Of Technology | Delivery of a solid body and/or a fluid using a linear Lorentz-force actuated needle-free jet injection system |
US9033898B2 (en) | 2010-06-23 | 2015-05-19 | Seventh Sense Biosystems, Inc. | Sampling devices and methods involving relatively little pain |
US9041541B2 (en) | 2010-01-28 | 2015-05-26 | Seventh Sense Biosystems, Inc. | Monitoring or feedback systems and methods |
US9113836B2 (en) | 2009-03-02 | 2015-08-25 | Seventh Sense Biosystems, Inc. | Devices and techniques associated with diagnostics, therapies, and other applications, including skin-associated applications |
US9119578B2 (en) | 2011-04-29 | 2015-09-01 | Seventh Sense Biosystems, Inc. | Plasma or serum production and removal of fluids under reduced pressure |
US9295417B2 (en) | 2011-04-29 | 2016-03-29 | Seventh Sense Biosystems, Inc. | Systems and methods for collecting fluid from a subject |
US9308326B2 (en) | 2005-02-11 | 2016-04-12 | Massachusetts Institute Of Technology | Controlled needle-free transport |
US9517030B2 (en) | 2009-09-01 | 2016-12-13 | Massachusetts Institute Of Technology | Nonlinear system identification techniques and devices for discovering dynamic and static tissue properties |
US10543310B2 (en) | 2011-12-19 | 2020-01-28 | Seventh Sense Biosystems, Inc. | Delivering and/or receiving material with respect to a subject surface |
US11177029B2 (en) | 2010-08-13 | 2021-11-16 | Yourbio Health, Inc. | Systems and techniques for monitoring subjects |
US11202895B2 (en) | 2010-07-26 | 2021-12-21 | Yourbio Health, Inc. | Rapid delivery and/or receiving of fluids |
Families Citing this family (378)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6464628B1 (en) | 1999-08-12 | 2002-10-15 | Obtech Medical Ag | Mechanical anal incontinence |
US6482145B1 (en) | 2000-02-14 | 2002-11-19 | Obtech Medical Ag | Hydraulic anal incontinence treatment |
US6471635B1 (en) | 2000-02-10 | 2002-10-29 | Obtech Medical Ag | Anal incontinence disease treatment with controlled wireless energy supply |
US6450173B1 (en) | 1999-08-12 | 2002-09-17 | Obtech Medical Ag | Heartburn and reflux disease treatment with controlled wireless energy supply |
EP1253879B1 (en) | 2000-02-10 | 2005-10-12 | Potencia Medical AG | Urinary incontinence treatment with wireless energy supply |
EP1253877B1 (en) | 2000-02-10 | 2005-05-11 | Potencia Medical AG | Mechanical impotence treatment apparatus |
AU759363B2 (en) | 2000-02-10 | 2003-04-10 | Implantica Patent Ltd. | Controlled urinary incontinence treatment |
AU778406B2 (en) | 2000-02-11 | 2004-12-02 | Potentica Ag | Controlled impotence treatment |
US20030125768A1 (en) | 2000-02-11 | 2003-07-03 | Forsell Peter | Impotence treatment apparatus with energy transforming means |
US20030100929A1 (en) | 2000-02-14 | 2003-05-29 | Peter Forsell | Controlled penile prosthesis |
EP1255514B1 (en) | 2000-02-14 | 2006-04-26 | Potencia Medical AG | Male impotence prosthesis apparatus with wireless energy supply |
DE60111019T2 (en) | 2000-02-14 | 2006-05-11 | Potencia Medical Ag | PROSTHESIS |
US7419481B2 (en) * | 2000-10-13 | 2008-09-02 | Alza Corporation | Apparatus and method for piercing skin with microprotrusions |
US8641644B2 (en) | 2000-11-21 | 2014-02-04 | Sanofi-Aventis Deutschland Gmbh | Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means |
DE60207902T2 (en) * | 2001-01-30 | 2006-06-14 | Nissan Chemical Ind Ltd | Isocyanurate compound and process for its preparation |
US9795747B2 (en) | 2010-06-02 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Methods and apparatus for lancet actuation |
US7025774B2 (en) | 2001-06-12 | 2006-04-11 | Pelikan Technologies, Inc. | Tissue penetration device |
US9427532B2 (en) | 2001-06-12 | 2016-08-30 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US9226699B2 (en) | 2002-04-19 | 2016-01-05 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling module with a continuous compression tissue interface surface |
US6966880B2 (en) * | 2001-10-16 | 2005-11-22 | Agilent Technologies, Inc. | Universal diagnostic platform |
US7429258B2 (en) | 2001-10-26 | 2008-09-30 | Massachusetts Institute Of Technology | Microneedle transport device |
US6908453B2 (en) * | 2002-01-15 | 2005-06-21 | 3M Innovative Properties Company | Microneedle devices and methods of manufacture |
US7858112B2 (en) * | 2002-02-28 | 2010-12-28 | Lintec Corporation | Percutaneous absorption system and percutaneous absorption method |
US7115108B2 (en) * | 2002-04-02 | 2006-10-03 | Becton, Dickinson And Company | Method and device for intradermally delivering a substance |
US6912417B1 (en) | 2002-04-05 | 2005-06-28 | Ichor Medical Systmes, Inc. | Method and apparatus for delivery of therapeutic agents |
US8702624B2 (en) | 2006-09-29 | 2014-04-22 | Sanofi-Aventis Deutschland Gmbh | Analyte measurement device with a single shot actuator |
US8579831B2 (en) | 2002-04-19 | 2013-11-12 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US8784335B2 (en) | 2002-04-19 | 2014-07-22 | Sanofi-Aventis Deutschland Gmbh | Body fluid sampling device with a capacitive sensor |
US7226461B2 (en) | 2002-04-19 | 2007-06-05 | Pelikan Technologies, Inc. | Method and apparatus for a multi-use body fluid sampling device with sterility barrier release |
US9248267B2 (en) | 2002-04-19 | 2016-02-02 | Sanofi-Aventis Deustchland Gmbh | Tissue penetration device |
US9795334B2 (en) | 2002-04-19 | 2017-10-24 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for penetrating tissue |
US9314194B2 (en) | 2002-04-19 | 2016-04-19 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
US20040039289A1 (en) * | 2002-04-30 | 2004-02-26 | Christensen Lars Hofmann | Needle insertion sensor |
CN1655834A (en) * | 2002-05-06 | 2005-08-17 | 贝克顿·迪金森公司 | Method and device for controlling drug pharmacokinetics |
EP1389476A1 (en) * | 2002-08-14 | 2004-02-18 | Precimedix S.A. | Programming device for a pump for injecting medicaments |
EP1539241A2 (en) * | 2002-08-30 | 2005-06-15 | Becton, Dickinson and Company | Method of controlling pharmacokinetics of immunomodulatory compounds |
US20120296233A9 (en) * | 2002-09-05 | 2012-11-22 | Freeman Dominique M | Methods and apparatus for an analyte detecting device |
JP2005537907A (en) | 2002-09-06 | 2005-12-15 | マサチューセッツ・インスティテュート・オブ・テクノロジー | Biological property measuring apparatus and method |
US8574895B2 (en) | 2002-12-30 | 2013-11-05 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus using optical techniques to measure analyte levels |
WO2004080306A1 (en) * | 2003-03-06 | 2004-09-23 | Lifescan, Inc. | System and method for piercing dermal tissue |
WO2006001797A1 (en) * | 2004-06-14 | 2006-01-05 | Pelikan Technologies, Inc. | Low pain penetrating |
US20070065463A1 (en) | 2003-06-20 | 2007-03-22 | Ronald Aung-Din | Topical therapy for the treatment of migranes, muscle sprains, muscle spasms, spasticity and related conditions |
CA2534823A1 (en) * | 2003-08-04 | 2005-02-24 | Alza Corporation | Method and device for enhancing transdermal agent flux |
US8282576B2 (en) | 2003-09-29 | 2012-10-09 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for an improved sample capture device |
EP1680014A4 (en) | 2003-10-14 | 2009-01-21 | Pelikan Technologies Inc | Method and apparatus for a variable user interface |
EP1527792A1 (en) | 2003-10-27 | 2005-05-04 | Novo Nordisk A/S | Medical injection device mountable to the skin |
WO2005044333A2 (en) | 2003-10-31 | 2005-05-19 | Alza Corporation | Self-actuating applicator for microprojection array |
US7361182B2 (en) | 2003-12-19 | 2008-04-22 | Lightnix, Inc. | Medical lancet |
DE602004016687D1 (en) * | 2003-12-22 | 2008-10-30 | Paul Hadvary | DERIVED SENSOR DEVICE |
EP1706171A1 (en) * | 2003-12-29 | 2006-10-04 | 3M Innovative Properties Company | Medical devices and kits including same |
EP1706026B1 (en) | 2003-12-31 | 2017-03-01 | Sanofi-Aventis Deutschland GmbH | Method and apparatus for improving fluidic flow and sample capture |
WO2005087311A1 (en) | 2004-03-08 | 2005-09-22 | Ichor Medical Systems, Inc. | Improved apparatus for electrically mediated delivery of therapeutic agents |
BRPI0509806A (en) * | 2004-04-12 | 2007-09-18 | Allergan Inc | multi-site injection system |
WO2005118060A2 (en) * | 2004-04-30 | 2005-12-15 | Boston Scientific Limited | Apparatus with partially insulated needle for measuring tissue impedance and method using same |
US8828203B2 (en) | 2004-05-20 | 2014-09-09 | Sanofi-Aventis Deutschland Gmbh | Printable hydrogels for biosensors |
EP1765194A4 (en) * | 2004-06-03 | 2010-09-29 | Pelikan Technologies Inc | Method and apparatus for a fluid sampling device |
US9775553B2 (en) * | 2004-06-03 | 2017-10-03 | Sanofi-Aventis Deutschland Gmbh | Method and apparatus for a fluid sampling device |
US8247946B2 (en) | 2004-06-14 | 2012-08-21 | Massachusetts Institute Of Technology | Electrochemical actuator |
JP2008503059A (en) | 2004-06-14 | 2008-01-31 | マサチューセッツ・インスティテュート・オブ・テクノロジー | Electrochemical methods, devices, and structures |
US7872396B2 (en) * | 2004-06-14 | 2011-01-18 | Massachusetts Institute Of Technology | Electrochemical actuator |
EP1768617A4 (en) * | 2004-06-29 | 2011-08-10 | Spine Wave Inc | Methods for treating defects and injuries of an intervertebral disc |
US20060030811A1 (en) * | 2004-08-03 | 2006-02-09 | Wong Patrick S | Method and device for enhancing transdermal agent flux |
US8696619B2 (en) * | 2004-08-10 | 2014-04-15 | Robert P. Schnall | Drug delivery devices |
ATE490037T1 (en) | 2004-08-16 | 2010-12-15 | Functional Microstructures Ltd | METHOD FOR PRODUCING A MICRONEEDLE OR A MICROIMPLANT |
US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
CA2580329C (en) | 2004-09-13 | 2015-01-06 | Chrono Therapeutics Inc. | Biosynchronous transdermal drug delivery |
WO2006055799A1 (en) * | 2004-11-18 | 2006-05-26 | 3M Innovative Properties Company | Masking method for coating a microneedle array |
CA2587387C (en) | 2004-11-18 | 2013-06-25 | 3M Innovative Properties Company | Method of contact coating a microneedle array |
US8057842B2 (en) | 2004-11-18 | 2011-11-15 | 3M Innovative Properties Company | Method of contact coating a microneedle array |
KR20130026511A (en) | 2004-11-18 | 2013-03-13 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | Low-profile microneedle array applicator |
JP4927752B2 (en) | 2004-11-18 | 2012-05-09 | スリーエム イノベイティブ プロパティズ カンパニー | Microneedle array applicator and holding device |
US20080009800A1 (en) * | 2004-12-02 | 2008-01-10 | Nickel Janice H | Transdermal drug delivery device |
CN100367906C (en) * | 2004-12-08 | 2008-02-13 | 圣美迪诺医疗科技(湖州)有限公司 | Endermic implantating biological sensors |
US7850645B2 (en) | 2005-02-11 | 2010-12-14 | Boston Scientific Scimed, Inc. | Internal medical devices for delivery of therapeutic agent in conjunction with a source of electrical power |
EP1709989A1 (en) * | 2005-04-04 | 2006-10-11 | Christoph Burckhardt AG | Tattoo machine |
JP5301985B2 (en) * | 2005-04-07 | 2013-09-25 | スリーエム イノベイティブ プロパティズ カンパニー | System and method for tool feedback sensing |
EP1709906A1 (en) * | 2005-04-07 | 2006-10-11 | F. Hoffmann-La Roche Ag | Method and device for blood sampling |
EP1877116A1 (en) | 2005-04-13 | 2008-01-16 | Novo Nordisk A/S | Medical skin mountable device and system |
EP2921169A1 (en) * | 2005-05-24 | 2015-09-23 | Chrono Therapeutics, Inc. | Portable drug delivery device including a detachable and replaceable administration or dosing element |
US8372040B2 (en) | 2005-05-24 | 2013-02-12 | Chrono Therapeutics, Inc. | Portable drug delivery device including a detachable and replaceable administration or dosing element |
WO2006128034A1 (en) * | 2005-05-25 | 2006-11-30 | Georgia Tech Research Corporation | Microneedles and methods for microinfusion |
CN101184523B (en) * | 2005-05-27 | 2011-04-13 | 奥林巴斯株式会社 | Device for introduction into subject |
US8505544B2 (en) * | 2005-05-31 | 2013-08-13 | The Board Of Trustees Of The Leland Stanford Junior University | Optically-implemented microsurgery system and approach |
EP1893256B1 (en) | 2005-06-16 | 2012-09-26 | Novo Nordisk A/S | Method and apparatus for assisting patients in self administration of medication |
EP1904158B1 (en) | 2005-06-24 | 2013-07-24 | 3M Innovative Properties Company | Collapsible patch with microneedle array |
JP5144510B2 (en) * | 2005-06-27 | 2013-02-13 | スリーエム イノベイティブ プロパティズ カンパニー | Microneedle array application device |
US9162037B2 (en) | 2005-07-06 | 2015-10-20 | Vascular Pathways, Inc. | Intravenous catheter insertion device and method of use |
IL175460A (en) | 2006-05-07 | 2011-05-31 | Doron Aurbach | Drug delivery device |
US9687186B2 (en) | 2005-07-21 | 2017-06-27 | Steadymed Ltd. | Drug delivery device |
US9486274B2 (en) | 2005-09-07 | 2016-11-08 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US9011473B2 (en) | 2005-09-07 | 2015-04-21 | Ulthera, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US10548659B2 (en) | 2006-01-17 | 2020-02-04 | Ulthera, Inc. | High pressure pre-burst for improved fluid delivery |
US9358033B2 (en) | 2005-09-07 | 2016-06-07 | Ulthera, Inc. | Fluid-jet dissection system and method for reducing the appearance of cellulite |
US8518069B2 (en) | 2005-09-07 | 2013-08-27 | Cabochon Aesthetics, Inc. | Dissection handpiece and method for reducing the appearance of cellulite |
US20070066934A1 (en) * | 2005-09-19 | 2007-03-22 | Transport Pharmaceuticals, Inc. | Electrokinetic delivery system and methods therefor |
US20070185432A1 (en) * | 2005-09-19 | 2007-08-09 | Transport Pharmaceuticals, Inc. | Electrokinetic system and method for delivering methotrexate |
JP4935286B2 (en) * | 2005-10-12 | 2012-05-23 | パナソニック株式会社 | Blood sensor |
WO2007045644A1 (en) | 2005-10-17 | 2007-04-26 | Novo Nordisk A/S | Vented drug reservoir unit |
SI2926847T1 (en) * | 2005-11-02 | 2022-10-28 | Medicaltree Patents Ltd. | Implantable infusion device with advanceable and retractable needle |
US7885793B2 (en) | 2007-05-22 | 2011-02-08 | International Business Machines Corporation | Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution |
US9248317B2 (en) | 2005-12-02 | 2016-02-02 | Ulthera, Inc. | Devices and methods for selectively lysing cells |
US9636035B2 (en) * | 2005-12-14 | 2017-05-02 | Scibase Ab | Medical apparatus for determination of biological conditions using impedance measurements |
JP4402648B2 (en) * | 2005-12-16 | 2010-01-20 | オリンパス株式会社 | Intra-subject introduction device |
US7736310B2 (en) | 2006-01-30 | 2010-06-15 | Abbott Diabetes Care Inc. | On-body medical device securement |
EP1815790A1 (en) * | 2006-02-04 | 2007-08-08 | Roche Diagnostics GmbH | Lancet device with impedance measuring unit |
US11318249B2 (en) | 2006-02-09 | 2022-05-03 | Deka Products Limited Partnership | Infusion pump assembly |
DE602007013723D1 (en) * | 2006-02-09 | 2011-05-19 | Deka Products Lp | SYSTEMS FOR DISPENSING FLUIDS IN PATCH SIZE |
EP1992386B1 (en) * | 2006-02-10 | 2011-11-09 | Hisamitsu Pharmaceutical Co., Inc. | Transdermal drug administration apparatus having microneedles |
US20070202186A1 (en) | 2006-02-22 | 2007-08-30 | Iscience Interventional Corporation | Apparatus and formulations for suprachoroidal drug delivery |
US7981034B2 (en) | 2006-02-28 | 2011-07-19 | Abbott Diabetes Care Inc. | Smart messages and alerts for an infusion delivery and management system |
JP5681362B2 (en) | 2006-03-14 | 2015-03-04 | ユニバーシティー オブ サザン カリフォルニア | MEMS device for delivery of therapeutic agents |
WO2007124411A1 (en) * | 2006-04-20 | 2007-11-01 | 3M Innovative Properties Company | Device for applying a microneedle array |
US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
WO2007131050A2 (en) * | 2006-05-02 | 2007-11-15 | Georgia Tech Research Corporation | Method for drug delivery to ocular tissue using microneedle |
US7621895B2 (en) * | 2006-05-17 | 2009-11-24 | Abbott Cardiovascular Systems Inc. | Needle array devices and methods |
US20070276318A1 (en) * | 2006-05-26 | 2007-11-29 | Mit, Llp | Iontosonic-microneedle applicator apparatus and methods |
US20090171269A1 (en) * | 2006-06-29 | 2009-07-02 | Abbott Diabetes Care, Inc. | Infusion Device and Methods Therefor |
US9119582B2 (en) * | 2006-06-30 | 2015-09-01 | Abbott Diabetes Care, Inc. | Integrated analyte sensor and infusion device and methods therefor |
JP2009545368A (en) * | 2006-08-01 | 2009-12-24 | エージェンシー フォー サイエンス,テクノロジー アンド リサーチ | Ultrasonic enhanced micro needle |
US8932216B2 (en) | 2006-08-07 | 2015-01-13 | Abbott Diabetes Care Inc. | Method and system for providing data management in integrated analyte monitoring and infusion system |
US8206296B2 (en) | 2006-08-07 | 2012-06-26 | Abbott Diabetes Care Inc. | Method and system for providing integrated analyte monitoring and infusion system therapy management |
EP2073888A4 (en) * | 2006-08-28 | 2011-01-19 | Agency Science Tech & Res | Microneedles and methods for fabricating microneedles |
JP2010502270A (en) * | 2006-08-29 | 2010-01-28 | アルザ・コーポレーシヨン | Chemical electrotransport with hydration measurements in hydratable reservoirs |
JP2010503454A (en) * | 2006-09-18 | 2010-02-04 | エージェンシー フォー サイエンス、テクノロジー アンド リサーチ | Needle structure and method for fabricating the needle structure |
US20100129656A1 (en) * | 2006-10-05 | 2010-05-27 | Technion Research & Develpment Foundation Ltd | Microtubes and methods of producing same |
DK2084802T3 (en) | 2006-10-25 | 2019-05-13 | Hoffmann La Roche | Uninterruptible power supply for medical device |
EP2076172A4 (en) * | 2006-10-27 | 2012-03-21 | Aretais Inc | Use of coherent raman techniques for medical diagnostic and therapeutic purposes, and calibration techniques for same |
US10525246B2 (en) * | 2006-12-22 | 2020-01-07 | Nanomed Skincare, Inc. | Microdevice and method for transdermal delivery and sampling of active substances |
US8845530B2 (en) * | 2007-01-02 | 2014-09-30 | Isense Corporation | Resposable biosensor assembly and method of sensing |
FR2912919B1 (en) * | 2007-02-22 | 2009-05-01 | Bernard Perriere | MINIATURIZED INJECTION DEVICE FOR MEDICAL USE |
US20080249469A1 (en) * | 2007-03-22 | 2008-10-09 | Ponnambalam Selvaganapathy | Method and apparatus for active control of drug delivery using electro-osmotic flow control |
US9114238B2 (en) | 2007-04-16 | 2015-08-25 | Corium International, Inc. | Solvent-cast microprotrusion arrays containing active ingredient |
GB2448493B (en) * | 2007-04-16 | 2009-10-14 | Dewan Fazlul Hoque Chowdhury | Microneedle transdermal delivery device |
EP2272432B1 (en) * | 2007-05-07 | 2012-03-14 | Vascular Pathways Inc. | Intravenous catheter insertion and blood sample devices |
WO2008154338A1 (en) * | 2007-06-07 | 2008-12-18 | Piezo Resonance Innovations, Inc. | Eye surgical tool |
US8641618B2 (en) | 2007-06-27 | 2014-02-04 | Abbott Diabetes Care Inc. | Method and structure for securing a monitoring device element |
US8085151B2 (en) | 2007-06-28 | 2011-12-27 | Abbott Diabetes Care Inc. | Signal converting cradle for medical condition monitoring and management system |
WO2009006291A1 (en) * | 2007-06-29 | 2009-01-08 | Piezo Resonance Innovations, Inc. | Medical tool for reduced penetration force |
US8328738B2 (en) | 2007-06-29 | 2012-12-11 | Actuated Medical, Inc. | Medical tool for reduced penetration force with feedback means |
US9987468B2 (en) | 2007-06-29 | 2018-06-05 | Actuated Medical, Inc. | Reduced force device for intravascular access and guidewire placement |
US8160900B2 (en) | 2007-06-29 | 2012-04-17 | Abbott Diabetes Care Inc. | Analyte monitoring and management device and method to analyze the frequency of user interaction with the device |
US10219832B2 (en) | 2007-06-29 | 2019-03-05 | Actuated Medical, Inc. | Device and method for less forceful tissue puncture |
EP2178584A2 (en) * | 2007-07-26 | 2010-04-28 | Entra Pharmaceuticals Inc. | Skin-patch pump comprising a changing-volume electrochemical actuator |
US8349554B2 (en) * | 2007-08-14 | 2013-01-08 | Fred Hutchinson Cancer Research Center | Needle array assembly and method for delivering therapeutic agents |
WO2009029044A1 (en) * | 2007-08-24 | 2009-03-05 | Agency For Science, Technology And Research | A system and method for detecting skin penetration |
WO2009029572A1 (en) * | 2007-08-24 | 2009-03-05 | Deka Products Limited Partnership | Microneedle systems and apparatus |
US9096845B2 (en) * | 2007-08-29 | 2015-08-04 | Technion Research & Development Foundation Limited | Encapsulation of bacteria and viruses in electrospun fibers |
US20090088682A1 (en) * | 2007-09-28 | 2009-04-02 | Seattle Medical Technologies | Wearable infusion device |
US8439940B2 (en) | 2010-12-22 | 2013-05-14 | Cabochon Aesthetics, Inc. | Dissection handpiece with aspiration means for reducing the appearance of cellulite |
JP5461427B2 (en) | 2007-12-17 | 2014-04-02 | ニューワールド ファーマシューティカルズ,エルエルシー | Integrated intradermal delivery, diagnosis and communication system |
MX364408B (en) | 2007-12-20 | 2019-04-25 | Univ Southern California | APPARATUS and METHODS FOR DELIVERING THERAPEUTIC AGENTS. |
US11357910B2 (en) | 2007-12-31 | 2022-06-14 | Deka Products Limited Partnership | Pump assembly with switch |
CA2919786C (en) | 2007-12-31 | 2019-10-22 | Deka Products Limited Partnership | Infusion pump assembly |
WO2009088956A2 (en) | 2007-12-31 | 2009-07-16 | Deka Products Limited Partnership | Infusion pump assembly |
FI20075978A0 (en) * | 2007-12-31 | 2007-12-31 | Katja Paassilta | Arrangement and method |
US8986253B2 (en) | 2008-01-25 | 2015-03-24 | Tandem Diabetes Care, Inc. | Two chamber pumps and related methods |
EP2244662B1 (en) | 2008-01-28 | 2021-09-29 | Implantica Patent Ltd. | Blood clot removal device and system |
WO2009096861A1 (en) | 2008-01-29 | 2009-08-06 | Milux Holding Sa | Methods and instruments for treating obesity and gastroesophageal reflux disease |
US9469919B2 (en) * | 2008-02-21 | 2016-10-18 | Technion Research & Development Foundation Ltd. | Method of attaching a cell-of-interest to a microtube |
US20090221893A1 (en) * | 2008-02-29 | 2009-09-03 | Path Scientific, Llc | Unitized Painfree Blood Glucose Measuring Device |
JP2009222474A (en) * | 2008-03-14 | 2009-10-01 | Panasonic Corp | Micro-liquid transfer apparatus and micro-mliquid transfer method |
WO2009137780A2 (en) | 2008-05-08 | 2009-11-12 | Replenish Pumps, Llc | Implantable pumps and cannulas therefor |
WO2009137785A2 (en) | 2008-05-08 | 2009-11-12 | Replenish Pumps, Llc | Drug-delivery pumps and methods of manufacture |
US9849238B2 (en) | 2008-05-08 | 2017-12-26 | Minipumps, Llc | Drug-delivery pump with intelligent control |
KR101383285B1 (en) | 2008-05-21 | 2014-04-08 | 테라젝트, 인코포레이티드 | Method of manufacturing solid solution perforator patches and uses thereof |
US8591410B2 (en) | 2008-05-30 | 2013-11-26 | Abbott Diabetes Care Inc. | Method and apparatus for providing glycemic control |
US8924159B2 (en) | 2008-05-30 | 2014-12-30 | Abbott Diabetes Care Inc. | Method and apparatus for providing glycemic control |
WO2010005507A1 (en) | 2008-06-30 | 2010-01-14 | Afgin Pharma, Llc | Topical regional neuro-affective therapy |
WO2010004721A1 (en) * | 2008-07-08 | 2010-01-14 | パナソニック株式会社 | Fluid conveying device using electrically conductive polymer |
US8868176B2 (en) * | 2008-07-22 | 2014-10-21 | New York University | Microelectrode-equipped subdural therapeutic agent delivery strip |
DK2626093T3 (en) * | 2008-08-28 | 2014-02-24 | Hoffmann La Roche | DEVICE FOR INCREASING HYPODERMIC insulin absorption |
US8408421B2 (en) | 2008-09-16 | 2013-04-02 | Tandem Diabetes Care, Inc. | Flow regulating stopcocks and related methods |
EP2334234A4 (en) | 2008-09-19 | 2013-03-20 | Tandem Diabetes Care Inc | Solute concentration measurement device and related methods |
ES2962384T3 (en) | 2008-10-10 | 2024-03-18 | Implantica Patent Ltd | Device for the treatment of female sexual dysfunction |
WO2010042058A1 (en) | 2008-10-10 | 2010-04-15 | Milux Holding S.A. | An improved artificial valve |
US8874215B2 (en) | 2008-10-10 | 2014-10-28 | Peter Forsell | System, an apparatus, and a method for treating a sexual dysfunctional female patient |
WO2010042019A1 (en) | 2008-10-10 | 2010-04-15 | Milux Holding Sa | Heart help device, system, and method |
EP2349078A4 (en) | 2008-10-10 | 2018-02-07 | Kirk Promotion LTD. | Fastening means for implantable medcial control assembly |
EP4282462A3 (en) | 2008-10-10 | 2024-02-21 | MedicalTree Patent Ltd. | Heart help device, system, and method |
EP2349448A1 (en) * | 2008-11-04 | 2011-08-03 | Janisys Limited | A transfer device for transferring a substance between the device and a subject |
US20110301628A1 (en) * | 2008-12-05 | 2011-12-08 | Yossi Gross | Techniques for use with a nail penetration device |
EP2370141A1 (en) | 2008-12-19 | 2011-10-05 | Janisys Limited | A fluid transfer device and an active substance cartridge for the fluid transfer device, and a method for controlling the pressure at which an active substance is delivered to a subject from a fluid transfer device |
US20100187132A1 (en) * | 2008-12-29 | 2010-07-29 | Don Alden | Determination of the real electrochemical surface areas of screen printed electrodes |
US9375169B2 (en) | 2009-01-30 | 2016-06-28 | Sanofi-Aventis Deutschland Gmbh | Cam drive for managing disposable penetrating member actions with a single motor and motor and control system |
US8781576B2 (en) * | 2009-03-17 | 2014-07-15 | Cardiothrive, Inc. | Device and method for reducing patient transthoracic impedance for the purpose of delivering a therapeutic current |
CN102427851B (en) | 2009-03-17 | 2015-04-15 | 卡迪欧思莱夫公司 | External defibrillator |
DE102009002019A1 (en) | 2009-03-31 | 2010-10-07 | Robert Bosch Gmbh | Applicator for the treatment of skin |
US8483967B2 (en) | 2009-04-29 | 2013-07-09 | Abbott Diabetes Care Inc. | Method and system for providing real time analyte sensor calibration with retrospective backfill |
WO2010125551A2 (en) * | 2009-04-29 | 2010-11-04 | Janisys Limited | A micro-needle device and apparatus and a method for applying a micro-needle element to a site on the skin of a subject |
CA2761060A1 (en) * | 2009-05-20 | 2010-12-23 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device |
US10952836B2 (en) | 2009-07-17 | 2021-03-23 | Peter Forsell | Vaginal operation method for the treatment of urinary incontinence in women |
US9949812B2 (en) | 2009-07-17 | 2018-04-24 | Peter Forsell | Vaginal operation method for the treatment of anal incontinence in women |
WO2011014704A2 (en) | 2009-07-30 | 2011-02-03 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
CA2769102C (en) | 2009-07-31 | 2017-09-19 | 3M Innovative Properties Company | Hollow microneedle arrays |
US9358064B2 (en) | 2009-08-07 | 2016-06-07 | Ulthera, Inc. | Handpiece and methods for performing subcutaneous surgery |
US11096708B2 (en) | 2009-08-07 | 2021-08-24 | Ulthera, Inc. | Devices and methods for performing subcutaneous surgery |
EP2467797B1 (en) | 2009-08-18 | 2017-07-19 | MiniPumps, LLC | Electrolytic drug-delivery pump with adaptive control |
US20110060202A1 (en) * | 2009-09-08 | 2011-03-10 | Seth Adrian Miller | Dehydration detector using micro-needles |
US9180246B2 (en) * | 2009-09-10 | 2015-11-10 | Sanofi-Aventis Deutschland Gmbh | Medicament container |
US8834423B2 (en) | 2009-10-23 | 2014-09-16 | University of Pittsburgh—of the Commonwealth System of Higher Education | Dissolvable microneedle arrays for transdermal delivery to human skin |
EP2493537B1 (en) * | 2009-10-30 | 2017-12-06 | Seventh Sense Biosystems, Inc. | Systems and methods for treating, sanitizing, and/or shielding the skin or devices applied to the skin |
US8685038B2 (en) | 2009-12-07 | 2014-04-01 | Incube Labs, Llc | Iontophoretic apparatus and method for marking of the skin |
US20110143310A1 (en) * | 2009-12-15 | 2011-06-16 | Hunter Ian W | Lorentz-Force Actuated Cleaning Device |
US20110172637A1 (en) * | 2010-01-08 | 2011-07-14 | Ratio, Inc. | Drug delivery device including tissue support structure |
JP5806236B2 (en) * | 2010-01-13 | 2015-11-10 | セブンス センス バイオシステムズ,インコーポレーテッド | Rapid delivery and / or collection of fluids |
EP2523603A2 (en) * | 2010-01-13 | 2012-11-21 | Seventh Sense Biosystems, Inc. | Sampling device interfaces |
EP3243435A1 (en) * | 2010-01-13 | 2017-11-15 | Seventh Sense Biosystems, Inc. | Sampling device interfaces |
US8366667B2 (en) * | 2010-02-11 | 2013-02-05 | Baxter International Inc. | Flow pulsatility dampening devices |
US8965476B2 (en) | 2010-04-16 | 2015-02-24 | Sanofi-Aventis Deutschland Gmbh | Tissue penetration device |
EP2560703A2 (en) | 2010-04-20 | 2013-02-27 | MiniPumps, LLC | Electrolytically driven drug pump devices |
US9629979B2 (en) * | 2010-04-28 | 2017-04-25 | Sanovas, Inc. | Pressure/Vacuum actuated catheter drug delivery probe |
EP2563450B1 (en) | 2010-04-28 | 2017-07-26 | Kimberly-Clark Worldwide, Inc. | Device for delivery of rheumatoid arthritis medication |
MX2012012567A (en) | 2010-04-28 | 2012-11-21 | Kimberly Clark Co | Method for increasing permeability of an epithelial barrier. |
JP5871907B2 (en) | 2010-04-28 | 2016-03-01 | キンバリー クラーク ワールドワイド インコーポレイテッド | Nanopatterned medical device with enhanced cell-cell interaction |
RU2585138C2 (en) | 2010-04-28 | 2016-05-27 | Кимберли-Кларк Ворлдвайд, Инк. | Medical devices for delivery of sirna |
WO2011140274A2 (en) | 2010-05-04 | 2011-11-10 | Corium International, Inc. | Method and device for transdermal delivery of parathyroid hormone using a microprojection array |
US8337457B2 (en) | 2010-05-05 | 2012-12-25 | Springleaf Therapeutics, Inc. | Systems and methods for delivering a therapeutic agent |
US9950139B2 (en) | 2010-05-14 | 2018-04-24 | C. R. Bard, Inc. | Catheter placement device including guidewire and catheter control elements |
US11925779B2 (en) | 2010-05-14 | 2024-03-12 | C. R. Bard, Inc. | Catheter insertion device including top-mounted advancement components |
US9872971B2 (en) | 2010-05-14 | 2018-01-23 | C. R. Bard, Inc. | Guidewire extension system for a catheter placement device |
US10384039B2 (en) | 2010-05-14 | 2019-08-20 | C. R. Bard, Inc. | Catheter insertion device including top-mounted advancement components |
US8932258B2 (en) | 2010-05-14 | 2015-01-13 | C. R. Bard, Inc. | Catheter placement device and method |
WO2011156095A2 (en) | 2010-06-10 | 2011-12-15 | The Regents Of The University Of California | Textile-based printable electrodes for electrochemical sensing |
US9227021B2 (en) | 2010-06-29 | 2016-01-05 | Genesis Biosystems, Inc. | Microneedle roller (MNR) infusion system |
ES2561824T3 (en) | 2010-07-16 | 2016-03-01 | Seventh Sense Biosystems, Inc. | Low pressure environment for fluid transfer devices |
US9055925B2 (en) | 2010-07-27 | 2015-06-16 | Carefusion 303, Inc. | System and method for reducing false alarms associated with vital-signs monitoring |
US8814792B2 (en) | 2010-07-27 | 2014-08-26 | Carefusion 303, Inc. | System and method for storing and forwarding data from a vital-signs monitor |
US9585620B2 (en) | 2010-07-27 | 2017-03-07 | Carefusion 303, Inc. | Vital-signs patch having a flexible attachment to electrodes |
US9420952B2 (en) | 2010-07-27 | 2016-08-23 | Carefusion 303, Inc. | Temperature probe suitable for axillary reading |
US9615792B2 (en) | 2010-07-27 | 2017-04-11 | Carefusion 303, Inc. | System and method for conserving battery power in a patient monitoring system |
US9017255B2 (en) | 2010-07-27 | 2015-04-28 | Carefusion 303, Inc. | System and method for saving battery power in a patient monitoring system |
US9357929B2 (en) | 2010-07-27 | 2016-06-07 | Carefusion 303, Inc. | System and method for monitoring body temperature of a person |
DE102010038733A1 (en) | 2010-07-30 | 2012-02-02 | Robert Bosch Gmbh | Modular microneedle transport device |
US9173994B2 (en) * | 2010-08-20 | 2015-11-03 | Purdue Research Foundation | Touch-actuated micropump for transdermal drug delivery and method of use |
WO2012042517A1 (en) * | 2010-09-27 | 2012-04-05 | Steadymed, Ltd. | Size-efficient drug-delivery device |
US20120271272A1 (en) | 2010-10-15 | 2012-10-25 | Iscience Interventional Corporation | Device for ocular access |
WO2012058192A1 (en) * | 2010-10-26 | 2012-05-03 | 7944942 Canada Inc. | Automatic medication injection device |
US9017289B2 (en) | 2010-11-03 | 2015-04-28 | Covidien Lp | Transdermal fluid delivery device |
WO2012064802A1 (en) | 2010-11-09 | 2012-05-18 | Seventh Sense Biosystems, Inc. | Systems and interfaces for blood sampling |
US8368285B2 (en) | 2010-12-17 | 2013-02-05 | Massachusette Institute Of Technology | Electrochemical actuators |
US8690833B2 (en) | 2011-01-31 | 2014-04-08 | Vascular Pathways, Inc. | Intravenous catheter and insertion device with reduced blood spatter |
US10130761B2 (en) | 2011-02-09 | 2018-11-20 | Becton, Dickinson And Company | Infusion systems |
ES2750035T3 (en) | 2011-02-25 | 2020-03-24 | Bard Inc C R | Medical component insertion device including a retractable needle |
US8696637B2 (en) | 2011-02-28 | 2014-04-15 | Kimberly-Clark Worldwide | Transdermal patch containing microneedles |
US10136845B2 (en) | 2011-02-28 | 2018-11-27 | Abbott Diabetes Care Inc. | Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same |
AU2012236099A1 (en) | 2011-03-31 | 2013-10-03 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
WO2012139593A2 (en) * | 2011-04-15 | 2012-10-18 | Rigshospitalet Copenhagen University Hospital | System and method for injecting a substance into a human body |
KR20140025475A (en) * | 2011-04-19 | 2014-03-04 | 인비지덤, 엘엘씨 | Method of producing substances with supersaturated gas??transdermal delivery device thereof??and uses thereof |
BR112013027010A2 (en) * | 2011-04-19 | 2016-12-27 | Invisiderm Llc | method of producing substances with supersaturated gas, device for their transdermal delivery, and their uses |
KR102237667B1 (en) | 2011-04-29 | 2021-04-12 | 세븐쓰 센스 바이오시스템즈, 인크. | Delivering and/or receiving fluids |
USD903101S1 (en) | 2011-05-13 | 2020-11-24 | C. R. Bard, Inc. | Catheter |
US8636696B2 (en) | 2011-06-10 | 2014-01-28 | Kimberly-Clark Worldwide, Inc. | Transdermal device containing microneedles |
WO2013006643A1 (en) | 2011-07-06 | 2013-01-10 | The Parkinson's Institute | Compositions and methods for treatment of symptoms in parkinson's disease patients |
US9737247B2 (en) | 2011-09-02 | 2017-08-22 | The Regents Of The University Of California | Microneedle arrays for biosensing and drug delivery |
BR112014009713A2 (en) | 2011-10-27 | 2017-04-18 | Kimberly Clark Co | transdermal administration of high viscosity bioactive agents |
US20170246439A9 (en) | 2011-10-27 | 2017-08-31 | Kimberly-Clark Worldwide, Inc. | Increased Bioavailability of Transdermally Delivered Agents |
JP6535464B2 (en) | 2011-10-27 | 2019-06-26 | ソレント・セラピューティクス・インコーポレイテッド | Implantable device for delivery of bioactive agents |
SG10201508662SA (en) | 2011-10-28 | 2015-11-27 | Presage Biosciences Inc | Methods for drug delivery |
US9317656B2 (en) | 2011-11-23 | 2016-04-19 | Abbott Diabetes Care Inc. | Compatibility mechanisms for devices in a continuous analyte monitoring system and methods thereof |
CA2859387A1 (en) | 2011-12-16 | 2013-06-20 | Moderna Therapeutics, Inc. | Modified nucleoside, nucleotide, and nucleic acid compositions |
DE102011089723A1 (en) * | 2011-12-23 | 2013-06-27 | Robert Bosch Gmbh | Microneedle array applicator and method of applying a microneedle array |
US10130800B2 (en) | 2012-01-27 | 2018-11-20 | Invisiderm, Llc | Method of producing substances with supersaturated gas, transdermal delivery device thereof, and uses thereof |
WO2013136185A2 (en) | 2012-03-13 | 2013-09-19 | Becton Dickinson France | Method of manufacture for a miniaturized drug delivery device |
ES2672239T3 (en) | 2012-03-15 | 2018-06-13 | Steadymed Ltd. | Improved pain reduction at the infusion site for drug delivery devices |
US9724462B2 (en) | 2012-03-19 | 2017-08-08 | Steadymed Ltd. | Fluid-connection mechanism for patch-pumps |
KR20130114996A (en) * | 2012-04-10 | 2013-10-21 | 삼성디스플레이 주식회사 | Display apparatus and fabricating method thereof |
CA3077452C (en) | 2012-05-01 | 2022-08-09 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Tip-loaded microneedle arrays for transdermal insertion |
US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
US9555186B2 (en) | 2012-06-05 | 2017-01-31 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
JP2015522351A (en) * | 2012-07-06 | 2015-08-06 | ザ ジェネラル ホスピタル コーポレイション | Method and apparatus for dermatological treatment |
US9782538B2 (en) | 2012-09-27 | 2017-10-10 | Becton, Dickinson And Company | Angled inserter for drug infusion |
CN104884049A (en) | 2012-11-08 | 2015-09-02 | 克莱尔塞德生物医学股份有限公司 | Methods and devices for the treatment of ocular diseases in human subjects |
JP6144355B2 (en) | 2012-11-26 | 2017-06-07 | モデルナティエックス インコーポレイテッドModernaTX,Inc. | Chemically modified mRNA |
ES2743404T3 (en) | 2012-12-21 | 2020-02-19 | Corium Inc | Matrix for therapeutic agent supply and manufacturing method |
WO2014113089A2 (en) | 2013-01-17 | 2014-07-24 | Moderna Therapeutics, Inc. | Signal-sensor polynucleotides for the alteration of cellular phenotypes |
US10105487B2 (en) | 2013-01-24 | 2018-10-23 | Chrono Therapeutics Inc. | Optimized bio-synchronous bioactive agent delivery system |
CN105102054B (en) | 2013-01-30 | 2018-04-20 | 血管通路股份有限公司 | The system and method placed for venipuncture and conduit |
CA2901568C (en) * | 2013-02-28 | 2021-02-16 | Kimberly-Clark Worldwide, Inc. | Transdermal drug delivery device |
EP2968887B1 (en) | 2013-03-12 | 2022-05-04 | Corium, Inc. | Microprojection applicators |
WO2014159813A1 (en) | 2013-03-13 | 2014-10-02 | Moderna Therapeutics, Inc. | Long-lived polynucleotide molecules |
US10080839B2 (en) | 2013-03-14 | 2018-09-25 | Becton, Dickinson And Company | Angled inserter for drug infusion |
US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
JP6098250B2 (en) * | 2013-03-14 | 2017-03-22 | セイコーエプソン株式会社 | Liquid transport device |
TWI592183B (en) * | 2013-03-15 | 2017-07-21 | 安美基公司 | Body contour adaptable autoinjector device |
AU2014237279B2 (en) | 2013-03-15 | 2018-11-22 | Corium Pharma Solutions, Inc. | Microarray with polymer-free microstructures, methods of making, and methods of use |
US9821113B2 (en) | 2013-03-15 | 2017-11-21 | Becton, Dickinson And Company | Automatic angled infusion set assembly |
CA2903459C (en) * | 2013-03-15 | 2024-02-20 | Corium International, Inc. | Multiple impact microprojection applicators and methods of use |
EP2968118B1 (en) | 2013-03-15 | 2022-02-09 | Corium, Inc. | Microarray for delivery of therapeutic agent and methods of use |
US9603995B2 (en) | 2013-03-15 | 2017-03-28 | Tandem Diabetes Care. Inc. | Device and method for setting therapeutic parameters for an infusion device |
AU2014259694B2 (en) | 2013-05-03 | 2018-11-08 | Clearside Biomedical, Inc. | Apparatus and methods for ocular injection |
US20140350518A1 (en) | 2013-05-23 | 2014-11-27 | Allergan, Inc. | Syringe extrusion accessory |
US20140350516A1 (en) | 2013-05-23 | 2014-11-27 | Allergan, Inc. | Mechanical syringe accessory |
US10188550B2 (en) | 2013-06-03 | 2019-01-29 | Clearside Biomedical, Inc. | Apparatus and methods for drug delivery using multiple reservoirs |
US9616243B2 (en) | 2013-06-14 | 2017-04-11 | Cardiothrive, Inc. | Dynamically adjustable multiphasic defibrillator pulse system and method |
US10279189B2 (en) | 2013-06-14 | 2019-05-07 | Cardiothrive, Inc. | Wearable multiphasic cardioverter defibrillator system and method |
US10149973B2 (en) | 2013-06-14 | 2018-12-11 | Cardiothrive, Inc. | Multipart non-uniform patient contact interface and method of use |
US9656094B2 (en) | 2013-06-14 | 2017-05-23 | Cardiothrive, Inc. | Biphasic or multiphasic pulse generator and method |
US9833630B2 (en) | 2013-06-14 | 2017-12-05 | Cardiothrive, Inc. | Biphasic or multiphasic pulse waveform and method |
US9907970B2 (en) | 2013-06-14 | 2018-03-06 | Cardiothrive, Inc. | Therapeutic system and method using biphasic or multiphasic pulse waveform |
EP3011992B1 (en) * | 2013-06-18 | 2019-10-16 | Hisamitsu Pharmaceutical Co., Inc. | Applicator |
US10039911B2 (en) | 2013-06-19 | 2018-08-07 | Hisamitsu Pharmaceutical Co., Inc. | Applicator |
US20150027241A1 (en) * | 2013-07-23 | 2015-01-29 | Diba Industries, Inc. | Piercing probes with offset conical piercing tip and fluid-sampling systems comprising the piercing probes |
WO2015059699A2 (en) | 2013-10-23 | 2015-04-30 | Valtech Cardio, Ltd. | Anchor magazine |
US20160367638A1 (en) | 2013-12-19 | 2016-12-22 | Crystal BYERS | LEPTIN mRNA COMPOSITIONS AND FORMULATIONS |
WO2015119906A1 (en) | 2014-02-05 | 2015-08-13 | Amgen Inc. | Drug delivery system with electromagnetic field generator |
GB201403773D0 (en) * | 2014-03-04 | 2014-04-16 | Univ Cardiff | Microneedle based cell delivery |
US10279106B1 (en) | 2014-05-08 | 2019-05-07 | Tandem Diabetes Care, Inc. | Insulin patch pump |
US10029048B2 (en) | 2014-05-13 | 2018-07-24 | Allergan, Inc. | High force injection devices |
CN106488782B (en) | 2014-06-03 | 2021-03-09 | 安姆根有限公司 | Device and method for assisting a user of a drug delivery device |
RU2710491C2 (en) | 2014-06-20 | 2019-12-26 | Клиасайд Байомедикал, Инк. | Device for drug injection into ocular tissue and method for drug injection into ocular tissue |
US10321858B2 (en) | 2014-08-18 | 2019-06-18 | Proteadx, Inc. | Apparatus and methods for transdermal sensing of analytes in interstitial fluid and associated data transmission systems |
EP3188714A1 (en) | 2014-09-04 | 2017-07-12 | Corium International, Inc. | Microstructure array, methods of making, and methods of use |
WO2016037127A1 (en) | 2014-09-05 | 2016-03-10 | C.R. Bard, Inc. | Catheter insertion device including retractable needle |
US10485925B2 (en) * | 2014-09-15 | 2019-11-26 | Sanofi | Medicament delivery device with rotatable housing on a base |
DE102014219719B4 (en) * | 2014-09-29 | 2018-05-03 | Ipr Intelligente Peripherien Für Roboter Gmbh | needle grippers |
US10226585B2 (en) | 2014-10-01 | 2019-03-12 | Allergan, Inc. | Devices for injection and dosing |
USD750223S1 (en) | 2014-10-14 | 2016-02-23 | Clearside Biomedical, Inc. | Medical injector for ocular injection |
CN105873514B (en) * | 2014-10-27 | 2018-10-26 | 深圳市光聚通讯技术开发有限公司 | Dynamic glucose harvester and host |
WO2016100055A1 (en) | 2014-12-19 | 2016-06-23 | Amgen Inc. | Drug delivery device with live button or user interface field |
US10799630B2 (en) | 2014-12-19 | 2020-10-13 | Amgen Inc. | Drug delivery device with proximity sensor |
EP3238352A4 (en) | 2014-12-23 | 2018-08-22 | Axell Wireless Ltd. | Harmonizing noise aggregation and noise management in distributed antenna system |
EP3045185A1 (en) * | 2015-01-16 | 2016-07-20 | Sanofi-Aventis Deutschland GmbH | Connector for a container filled with a liquid medicament |
AU2016211330A1 (en) | 2015-01-28 | 2017-08-03 | Chrono Therapeutics Inc. | Drug delivery methods and systems |
US10583245B2 (en) * | 2015-02-17 | 2020-03-10 | Amgen Inc. | Drug delivery device with vacuum assisted securement and/or feedback |
CA2976544A1 (en) | 2015-03-10 | 2016-09-15 | Allergan Pharmaceuticals Holdings (Ireland) Unlimited Company | Multiple needle injector |
JP2018511127A (en) | 2015-03-12 | 2018-04-19 | クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. | Craving input and support system |
US10441768B2 (en) | 2015-03-18 | 2019-10-15 | University of Pittsburgh—of the Commonwealth System of Higher Education | Bioactive components conjugated to substrates of microneedle arrays |
USD903100S1 (en) | 2015-05-01 | 2020-11-24 | C. R. Bard, Inc. | Catheter placement device |
JP6784352B2 (en) * | 2015-05-11 | 2020-11-11 | 国立大学法人 東京医科歯科大学 | Insulin delivery device |
JP7016261B2 (en) | 2015-05-15 | 2022-02-21 | シー・アール・バード・インコーポレーテッド | Catheter indwelling device with extendable needle safety component |
US10463847B2 (en) | 2015-06-11 | 2019-11-05 | Steadymed Ltd. | Infusion set |
US10857093B2 (en) | 2015-06-29 | 2020-12-08 | Corium, Inc. | Microarray for delivery of therapeutic agent, methods of use, and methods of making |
US10940292B2 (en) | 2015-07-08 | 2021-03-09 | Actuated Medical, Inc. | Reduced force device for intravascular access and guidewire placement |
US11793543B2 (en) | 2015-09-18 | 2023-10-24 | Obvius Robotics, Inc. | Device and method for automated insertion of penetrating member |
US11684763B2 (en) | 2015-10-16 | 2023-06-27 | University of Pittsburgh—of the Commonwealth System of Higher Education | Multi-component bio-active drug delivery and controlled release to the skin by microneedle array devices |
WO2017120322A1 (en) | 2016-01-05 | 2017-07-13 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Skin microenvironment targeted delivery for promoting immune and other responses |
US10390901B2 (en) | 2016-02-10 | 2019-08-27 | Clearside Biomedical, Inc. | Ocular injection kit, packaging, and methods of use |
CN108778248A (en) * | 2016-02-19 | 2018-11-09 | 北卡罗来纳州立大学 | Method and composition related with physiological responses micropin delivery system |
BR112018069659A2 (en) | 2016-03-28 | 2019-02-12 | Ichor Medical Systems, Inc. | method and apparatus for the application of therapeutic agents |
AU2017246114B2 (en) | 2016-04-08 | 2022-03-17 | Allergan, Inc. | Aspiration and injection device |
JP2019514581A (en) | 2016-05-02 | 2019-06-06 | クリアサイド バイオメディカル,インコーポレイテッド | Systems and methods for ocular drug delivery |
US20200306518A1 (en) * | 2016-05-20 | 2020-10-01 | Uprax Microsolutions B.V. | System and method for applying microneedles |
NL2016807B1 (en) * | 2016-05-20 | 2017-11-27 | Uprax | System and method for applying microneedles |
US10220195B2 (en) * | 2016-06-08 | 2019-03-05 | Eclipse Medcorp, Llc | Radio frequency needling device for use with disposable needle cartridges |
IL305537A (en) | 2016-08-12 | 2023-10-01 | Clearside Biomedical Inc | Devices and methods for adjusting the insertion depth of a needle for medicament delivery |
WO2018049413A1 (en) | 2016-09-12 | 2018-03-15 | C.R. Bard, Inc. | Blood control for a catheter insertion device |
US11241563B2 (en) | 2016-12-22 | 2022-02-08 | Johnson & Johnson Consumer Inc. | Microneedle arrays and methods for making and using |
EP3338832A1 (en) * | 2016-12-23 | 2018-06-27 | Sanofi-Aventis Deutschland GmbH | Medicament delivery device |
JP2020503950A (en) | 2017-01-06 | 2020-02-06 | クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. | Device and method for transdermal drug delivery |
JP6953541B2 (en) | 2017-03-01 | 2021-10-27 | シー・アール・バード・インコーポレーテッドC R Bard Incorporated | Catheter insertion device |
USD867582S1 (en) | 2017-03-24 | 2019-11-19 | Allergan, Inc. | Syringe device |
CN109833562B (en) * | 2017-11-27 | 2024-03-15 | 苏州纳通生物纳米技术有限公司 | Disposable self-destruction type vibrating head assembly and permeation promoting instrument using same |
US10828500B2 (en) | 2017-12-22 | 2020-11-10 | Cardiothrive, Inc. | External defibrillator |
BR112020013872A2 (en) * | 2018-01-07 | 2020-12-01 | Avraham Amir | high-load microneedles and skin augmentation compositions |
US11389626B2 (en) | 2018-03-07 | 2022-07-19 | Bard Access Systems, Inc. | Guidewire advancement and blood flashback systems for a medical device insertion system |
US11090506B2 (en) * | 2018-05-15 | 2021-08-17 | Omm Imports, Inc. | Disposable product cap and assembly having a manually usable thermo-optical device for skin care |
AU2019279884A1 (en) | 2018-05-29 | 2020-12-10 | Morningside Venture Investments Limited | Drug delivery methods and systems |
WO2020003247A2 (en) * | 2018-06-29 | 2020-01-02 | Johnson & Johnson Consumer Inc. | Three-dimensional microfluidics devices for the delivery of actives |
USD921884S1 (en) | 2018-07-27 | 2021-06-08 | Bard Access Systems, Inc. | Catheter insertion device |
FR3084578B1 (en) * | 2018-08-03 | 2024-01-12 | Pkvitality | MANAGEMENT OF MICRONEEDLE INVESTMENT |
EP3927394A1 (en) | 2019-02-22 | 2021-12-29 | DEKA Products Limited Partnership | Infusion set and inserter assembly systems and methods |
WO2020188484A1 (en) * | 2019-03-19 | 2020-09-24 | King Abdullah University Of Science And Technology | Miniaturized delivery system and method |
US11590332B2 (en) * | 2019-04-17 | 2023-02-28 | Path Scientific, Llc | Precision microneedling device and methods of use |
GB201908043D0 (en) * | 2019-06-05 | 2019-07-17 | Lekkos Vasileios | Transdermal patch for therapeutic uses |
KR102279603B1 (en) * | 2019-06-11 | 2021-07-20 | (주)비올 | Needle assembly, skin stimulator including the same, and manufacturing method thereof |
JP7455187B2 (en) | 2019-07-12 | 2024-03-25 | キューラブ・メディカル・リミテッド | Electrochemical FET sensor |
WO2021020730A2 (en) * | 2019-07-26 | 2021-02-04 | 주식회사 림사이언스 | Apparatus for applying pressure to medical needle |
CN213312819U (en) | 2019-08-19 | 2021-06-01 | 贝克顿·迪金森公司 | Midline catheter placement device |
US20220379022A1 (en) * | 2019-10-30 | 2022-12-01 | Thermalin, Inc. | Agent delivery systems, devices, and methods |
WO2021167410A1 (en) * | 2020-02-20 | 2021-08-26 | 쥬빌리바이오텍 주식회사 | Applicator for drug delivery and microneedle patch used therefor |
DK4048152T3 (en) | 2020-07-29 | 2024-03-11 | Biolinq Incorporated | SYSTEM FOR CONTINUOUS ANALYTE MONITORING WITH MICRON NEEDLE ARRANGEMENT |
CN112370653B (en) * | 2020-11-12 | 2022-08-30 | 深圳市圣通生物科技有限公司 | Spray disinfection type nanometer microneedle mesoderm leading-in beauty instrument |
WO2022187821A1 (en) * | 2021-03-01 | 2022-09-09 | Bluexthermal, Inc. | Device and method for thermal modulation of tissue |
US11452474B1 (en) | 2021-04-14 | 2022-09-27 | Satio, Inc. | Dual lever dermal patch system |
EP4153276A4 (en) | 2021-05-08 | 2023-11-08 | Biolinq, Inc. | Fault detection for microneedle array based continuous analyte monitoring device |
US11877848B2 (en) | 2021-11-08 | 2024-01-23 | Satio, Inc. | Dermal patch for collecting a physiological sample |
US11510602B1 (en) | 2021-11-08 | 2022-11-29 | Satio, Inc. | Dermal patch for collecting a physiological sample |
EP4295873A1 (en) * | 2022-06-21 | 2023-12-27 | National University of Ireland Galway | An infusion catheter system |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR757501A (en) * | 1932-09-23 | 1933-12-28 | Automatic device for handling injection syringes | |
US3727614A (en) * | 1971-05-13 | 1973-04-17 | Merck & Co Inc | Multiple dosage inoculator |
WO1993017754A1 (en) * | 1992-03-13 | 1993-09-16 | Elan Medical Technologies Limited | Drug delivery devices |
WO1994023777A1 (en) * | 1993-04-08 | 1994-10-27 | Elan Medical Technologies Limited | Intradermal injection device |
Family Cites Families (140)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3537A (en) | 1844-04-13 | X g gupping instrument | ||
US447225A (en) * | 1891-02-24 | Machine for attaching stays to the corners of boxes | ||
US3659A (en) * | 1844-07-11 | Machine for hulling and pearling rice | ||
US1934043A (en) * | 1929-05-17 | 1933-11-07 | Standard Oil Dev Co | Process of improvement of lubricating oils |
DE596981C (en) | 1931-10-30 | 1934-05-12 | Mario Demarchi Dr | Injection syringe |
US2088780A (en) | 1936-10-09 | 1937-08-03 | Sigurd E Follese | Massage device |
US2763935A (en) | 1954-06-11 | 1956-09-25 | Purdne Res Foundation | Determining depth of layers of fat and of muscle on an animal body |
US2945496A (en) | 1958-08-18 | 1960-07-19 | Fosdal Alfred | Dental instrument for immobilizing tissue |
DE1115722B (en) | 1960-04-30 | 1961-10-26 | Hoechst Ag | Metal anode for the electrolytic separation of chlorine |
GB1128329A (en) | 1964-12-23 | 1968-09-25 | Nat Res Dev | Electrodes for making electrical contact to the living body of a mammal |
US3568735A (en) * | 1968-06-26 | 1971-03-09 | Cooke Eng Co | Laboratory microtitration dispensing apparatus |
US3568732A (en) | 1969-02-28 | 1971-03-09 | Kelly James A Jun | Splice straightener for aerial conductors |
US3659600A (en) | 1970-02-24 | 1972-05-02 | Estin Hans H | Magnetically operated capsule for administering drugs |
US3964482A (en) | 1971-05-17 | 1976-06-22 | Alza Corporation | Drug delivery device |
US3738493A (en) | 1971-09-24 | 1973-06-12 | Analytical Instr Spec | Apparatus for simultaneous application of samples to thin layer chromatography plates |
BE795384A (en) | 1972-02-14 | 1973-08-13 | Ici Ltd | DRESSINGS |
CH557178A (en) | 1972-08-10 | 1974-12-31 | Siemens Ag | DEVICE FOR DISPENSING DRUGS. |
US3923060A (en) | 1974-04-23 | 1975-12-02 | Jr Everett H Ellinwood | Apparatus and method for implanted self-powered medication dispensing having timing and evaluator means |
US4140109A (en) | 1977-10-17 | 1979-02-20 | Savic Michael I | Impedance-based method and apparatus for monitoring cryodestruction in controlled cryosurgery |
FR2460343A1 (en) | 1979-06-29 | 1981-01-23 | Solvay | CATHODE FOR THE ELECTROLYTIC PRODUCTION OF HYDROGEN |
JPS5683360A (en) * | 1979-12-10 | 1981-07-07 | Olympus Optical Co | Pneumoperitoneum needle |
US4447225A (en) | 1982-03-22 | 1984-05-08 | Taff Barry E | Multidose jet injector |
US4619652A (en) | 1982-12-23 | 1986-10-28 | Alza Corporation | Dosage form for use in a body mounted pump |
US4505710A (en) | 1983-05-13 | 1985-03-19 | Collins Earl R | Implantable fluid dispensing system |
DE3502913C1 (en) | 1985-01-29 | 1986-07-03 | Günter Prof. Dr.rer.nat. 5100 Aachen Rau | Sensor for non-invasive detection of electrophysiological values |
US4777599A (en) | 1985-02-26 | 1988-10-11 | Gillette Company | Viscoelastometry of skin using shear wave propagation |
FR2594341B1 (en) * | 1986-02-14 | 1990-08-10 | Charton Jean Pierre | INJECTOR APPARATUS FOR THE PRACTICE OF MESOTHERAPY |
AT384737B (en) | 1986-04-04 | 1987-12-28 | Thoma Dipl Ing Dr Techn Herwig | DEVICE FOR CONTINUOUSLY DELIVERING LIQUID MEDICINAL PRODUCTS |
AU7847487A (en) * | 1986-09-18 | 1988-02-04 | Selfridge, A.R. | Cannulation of blood vessels |
CA1283827C (en) * | 1986-12-18 | 1991-05-07 | Giorgio Cirelli | Appliance for injection of liquid formulations |
US4808156A (en) | 1987-03-09 | 1989-02-28 | Dean Consuelo M | Cannular instrument and method for inserting a cannular instrument into a vein |
US6056716A (en) | 1987-06-08 | 2000-05-02 | D'antonio Consultants International Inc. | Hypodermic fluid dispenser |
DD262803A1 (en) | 1987-08-05 | 1988-12-14 | Transform Roentgen Matern Veb | INJECTION DEVICE |
US5312486A (en) | 1987-12-24 | 1994-05-17 | Frank Meyer | Water-containing, hardenable foam compositions with inorganic components and process for their preparation |
US4989614A (en) | 1988-02-23 | 1991-02-05 | Vance Products Incorporated | Fine-needle aspiration cell sampling methods |
CA2008262A1 (en) * | 1989-01-30 | 1990-07-30 | John A. Gilly | Clinical applicator |
US5062834A (en) | 1989-02-24 | 1991-11-05 | Product Development (S.G.Z.) Ltd | Device for dispensing a liquid particularly useful for delivering medicaments at a predetermined rate |
US5425706A (en) | 1989-02-24 | 1995-06-20 | S. I. Scientific Innovations Ltd. | Dispensing device particularly useful for dispensing nutritional liquids |
JPH0648975B2 (en) | 1989-10-02 | 1994-06-29 | 俊郎 樋口 | Micro injection device and injection control method thereof |
US5262128A (en) | 1989-10-23 | 1993-11-16 | The United States Of America As Represented By The Department Of Health And Human Services | Array-type multiple cell injector |
EP0429842B1 (en) | 1989-10-27 | 1996-08-28 | Korea Research Institute Of Chemical Technology | Device for the transdermal administration of protein or peptide drug |
US6090790A (en) | 1989-12-14 | 2000-07-18 | Eriksson; Elof | Gene delivery by microneedle injection |
US5697901A (en) | 1989-12-14 | 1997-12-16 | Elof Eriksson | Gene delivery by microneedle injection |
US5092901A (en) | 1990-06-06 | 1992-03-03 | The Royal Institution For The Advancement Of Learning (Mcgill University) | Shape memory alloy fibers having rapid twitch response |
US5527288A (en) | 1990-12-13 | 1996-06-18 | Elan Medical Technologies Limited | Intradermal drug delivery device and method for intradermal delivery of drugs |
US5156591A (en) | 1990-12-13 | 1992-10-20 | S. I. Scientific Innovations Ltd. | Skin electrode construction and transdermal drug delivery device utilizing same |
TW279133B (en) | 1990-12-13 | 1996-06-21 | Elan Med Tech | |
US5279547A (en) | 1991-01-03 | 1994-01-18 | Alcon Surgical Inc. | Computer controlled smart phacoemulsification method and apparatus |
SE9101022D0 (en) * | 1991-01-09 | 1991-04-08 | Paal Svedman | MEDICAL SUSPENSION DEVICE |
US5312456A (en) | 1991-01-31 | 1994-05-17 | Carnegie Mellon University | Micromechanical barb and method for making the same |
WO1993009842A1 (en) | 1991-11-13 | 1993-05-27 | Elan Corporation, Plc | Drug delivery device |
US6048337A (en) | 1992-01-07 | 2000-04-11 | Principal Ab | Transdermal perfusion of fluids |
KR0145453B1 (en) | 1992-01-21 | 1998-07-01 | 알렌 제이 | Electrosurgical trocar control device |
US5252023A (en) * | 1992-02-10 | 1993-10-12 | Kelly Kevin M | Lifting apparatus |
JP2572823Y2 (en) | 1992-02-13 | 1998-05-25 | 株式会社アドバンス | Simple blood sampler |
WO1993020784A1 (en) | 1992-04-10 | 1993-10-28 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University | A microneedle for injection of ocular blood vessels |
US5478328A (en) | 1992-05-22 | 1995-12-26 | Silverman; David G. | Methods of minimizing disease transmission by used hypodermic needles, and hypodermic needles adapted for carrying out the method |
JPH0698920A (en) * | 1992-09-21 | 1994-04-12 | Hayashi Shigetada | Acupuncture precise measuring instrument |
US5354273A (en) | 1992-12-14 | 1994-10-11 | Mallinckrodt Medical, Inc. | Delivery apparatus with pressure controlled delivery |
US5478323A (en) * | 1993-04-02 | 1995-12-26 | Eli Lilly And Company | Manifold for injection apparatus |
US5335668A (en) * | 1993-04-30 | 1994-08-09 | Medical Scientific, Inc. | Diagnostic impedance measuring system for an insufflation needle |
JP3494183B2 (en) * | 1993-08-10 | 2004-02-03 | 株式会社アドバンス | Simple blood collection device |
EP0746365A4 (en) | 1993-09-14 | 1997-05-21 | North Shore Lab Pty Ltd | Injection device |
US5389222A (en) | 1993-09-21 | 1995-02-14 | The United States Of America As Represented By The United States Department Of Energy | Spring-loaded polymeric gel actuators |
US5599345A (en) | 1993-11-08 | 1997-02-04 | Zomed International, Inc. | RF treatment apparatus |
US5997501A (en) | 1993-11-18 | 1999-12-07 | Elan Corporation, Plc | Intradermal drug delivery device |
CA2149836C (en) | 1994-05-23 | 1999-07-06 | Sang Bae Choi | Perforating device for dermal administration |
CA2149943C (en) | 1994-05-23 | 1999-07-13 | Kwang Kyun Jang | Skin perforating device for transdermal medication |
US5591139A (en) | 1994-06-06 | 1997-01-07 | The Regents Of The University Of California | IC-processed microneedles |
US5649423A (en) | 1994-06-07 | 1997-07-22 | Sandia Corporation | Micromechanism linear actuator with capillary force sealing |
DE4420232A1 (en) | 1994-06-07 | 1995-12-14 | Robert Waltereit | Penetration depth checking device for hollow needle or probe inserted in human or animal patient |
US5478315A (en) | 1994-08-08 | 1995-12-26 | Brothers Family Investments, L.C. | Local anesthetic injection system |
US5432098A (en) | 1994-10-31 | 1995-07-11 | Dynatech Precision Sampling Corporation | Apparatus, and process, for automatically sampling solids and semi-solids materials for analysis |
IE72524B1 (en) * | 1994-11-04 | 1997-04-23 | Elan Med Tech | Analyte-controlled liquid delivery device and analyte monitor |
GB9508606D0 (en) | 1995-04-27 | 1995-06-14 | Svedman Paul | Suction blister sampling |
AU5740496A (en) | 1995-05-22 | 1996-12-11 | General Hospital Corporation, The | Micromechanical device and method for enhancing delivery of compounds through the skin |
WO1996037256A1 (en) | 1995-05-22 | 1996-11-28 | Silicon Microdevices, Inc. | Micromechanical patch for enhancing the delivery of compounds through the skin |
US5827216A (en) * | 1995-06-07 | 1998-10-27 | Cormedics Corp. | Method and apparatus for accessing the pericardial space |
ZA9610374B (en) * | 1995-12-11 | 1997-06-23 | Elan Med Tech | Cartridge-based drug delivery device |
JPH09192218A (en) * | 1996-01-16 | 1997-07-29 | Hitachi Ltd | Blood-sugar level control system |
JPH09239031A (en) * | 1996-03-09 | 1997-09-16 | Honda Electron Co Ltd | Injector mounting ultrasonic vibrator transducer |
US5843016A (en) | 1996-03-18 | 1998-12-01 | Physion S.R.L. | Electromotive drug administration for treatment of acute urinary outflow obstruction |
US6117155A (en) | 1996-05-01 | 2000-09-12 | Lee; Young H. | Coated needle for use with an intramuscular stimulation treatment device |
US5785688A (en) | 1996-05-07 | 1998-07-28 | Ceramatec, Inc. | Fluid delivery apparatus and method |
US5954668A (en) | 1996-06-14 | 1999-09-21 | Medrad, Inc. | Extravasation detector using microwave radiometry |
EP0914178B1 (en) | 1996-06-18 | 2003-03-12 | Alza Corporation | Device for enhancing transdermal agent delivery or sampling |
DE69722414T2 (en) | 1996-07-03 | 2004-05-19 | Altea Therapeutics Corp. | MULTIPLE MECHANICAL MICROPERFORATION OF SKIN OR MUCOSA |
JPH1043296A (en) * | 1996-08-05 | 1998-02-17 | Terumo Corp | Chemical injecting apparatus |
ATE231015T1 (en) | 1996-09-17 | 2003-02-15 | Deka Products Lp | SYSTEM FOR DELIVERY OF MEDICATION THROUGH TRANSPORT |
US6027459A (en) | 1996-12-06 | 2000-02-22 | Abbott Laboratories | Method and apparatus for obtaining blood for diagnostic tests |
SE9604564D0 (en) | 1996-12-12 | 1996-12-12 | Paal Svedman | Method and apparatus for conducting electrical currents |
US6246904B1 (en) | 1996-12-17 | 2001-06-12 | Alza Corporation | Electrotransport drug delivery reservoirs containing inert fillers |
US5928194A (en) | 1997-04-07 | 1999-07-27 | Maget; Henri J. R. | Self-contained liquid microdispenser |
US5928207A (en) | 1997-06-30 | 1999-07-27 | The Regents Of The University Of California | Microneedle with isotropically etched tip, and method of fabricating such a device |
US5972013A (en) | 1997-09-19 | 1999-10-26 | Comedicus Incorporated | Direct pericardial access device with deflecting mechanism and method |
JPH11137684A (en) * | 1997-11-12 | 1999-05-25 | Hiroshi Oya | Indolent and safe syringe |
EP1032441B1 (en) * | 1997-11-26 | 2004-03-03 | E-Z-Em, Inc. | Extravasation detection device |
US6918901B1 (en) * | 1997-12-10 | 2005-07-19 | Felix Theeuwes | Device and method for enhancing transdermal agent flux |
WO1999029365A1 (en) | 1997-12-11 | 1999-06-17 | Alza Corporation | Device for enhancing transdermal agent flux |
WO1999029364A1 (en) | 1997-12-11 | 1999-06-17 | Alza Corporation | Device for enhancing transdermal agent flux |
US6126629A (en) | 1997-12-18 | 2000-10-03 | Bausch & Lomb Surgical, Inc. | Multiple port phaco needle |
US6154673A (en) * | 1997-12-30 | 2000-11-28 | Agilent Technologies, Inc. | Multilingual defibrillator |
US6048204A (en) * | 1998-02-03 | 2000-04-11 | Lifecore Biomedical, Inc. | Self tapping screw type dental implant |
US5957895A (en) | 1998-02-20 | 1999-09-28 | Becton Dickinson And Company | Low-profile automatic injection device with self-emptying reservoir |
US6391005B1 (en) * | 1998-03-30 | 2002-05-21 | Agilent Technologies, Inc. | Apparatus and method for penetration with shaft having a sensor for sensing penetration depth |
US5971998A (en) | 1998-03-31 | 1999-10-26 | Donald G. Russell | Support device and method for controlling breast thickness during stereotactic guided needle biopsy |
EP1077634B1 (en) | 1998-05-13 | 2003-07-30 | Cygnus, Inc. | Monitoring of physiological analytes |
WO1999058050A1 (en) | 1998-05-13 | 1999-11-18 | Cygnus, Inc. | Signal processing for measurement of physiological analytes |
CA2334174A1 (en) | 1998-06-04 | 1999-12-09 | Izrail Tsals | Gas driven drug delivery device |
AU767122B2 (en) | 1998-06-10 | 2003-10-30 | Georgia Tech Research Corporation | Microneedle devices and methods of manufacture and use thereof |
US6678556B1 (en) | 1998-07-13 | 2004-01-13 | Genetronics, Inc. | Electrical field therapy with reduced histopathological change in muscle |
GB9815820D0 (en) | 1998-07-22 | 1998-09-16 | Secr Defence | Improvements relating to micro-machining |
GB9815819D0 (en) | 1998-07-22 | 1998-09-16 | Secr Defence | Transferring materials into cells and a microneedle array |
JP2002521147A (en) | 1998-07-27 | 2002-07-16 | メディ−ジェクト コーポレイション | Loading mechanism for use in medical syringe assemblies |
AU6151599A (en) | 1998-09-18 | 2000-04-10 | University Of Utah Research Foundation | Surface micromachined microneedles |
DE19843733A1 (en) | 1998-09-24 | 2000-03-30 | Voith Sulzer Papiertech Patent | Wiper blade assembly coating paper or card bands with optionally-viscous liquid, employs system of leaf spring tensioning which forms ductor chamber and is readily replaced and adjusted |
US6148232A (en) | 1998-11-09 | 2000-11-14 | Elecsys Ltd. | Transdermal drug delivery and analyte extraction |
US6317630B1 (en) | 1999-01-29 | 2001-11-13 | Yossi Gross | Drug delivery device |
US6132449A (en) | 1999-03-08 | 2000-10-17 | Agilent Technologies, Inc. | Extraction and transportation of blood for analysis |
US6319230B1 (en) | 1999-05-07 | 2001-11-20 | Scimed Life Systems, Inc. | Lateral needle injection apparatus and method |
US6743211B1 (en) * | 1999-11-23 | 2004-06-01 | Georgia Tech Research Corporation | Devices and methods for enhanced microneedle penetration of biological barriers |
ATE462468T1 (en) | 1999-06-04 | 2010-04-15 | Georgia Tech Res Inst | DEVICES FOR ENLARGED MICRONEEDLES PENETRATION IN BIOLOGICAL SKIN LAYERS |
US6611707B1 (en) | 1999-06-04 | 2003-08-26 | Georgia Tech Research Corporation | Microneedle drug delivery device |
US6256533B1 (en) | 1999-06-09 | 2001-07-03 | The Procter & Gamble Company | Apparatus and method for using an intracutaneous microneedle array |
US6379324B1 (en) | 1999-06-09 | 2002-04-30 | The Procter & Gamble Company | Intracutaneous microneedle array apparatus |
US6607495B1 (en) * | 1999-06-18 | 2003-08-19 | University Of Virginia Patent Foundation | Apparatus for fluid transport and related method thereof |
US6408204B1 (en) | 1999-07-28 | 2002-06-18 | Medrad, Inc. | Apparatuses and methods for extravasation detection |
EP1235611B1 (en) * | 1999-11-15 | 2005-09-07 | Velcro Industries B.V. | Skin attachment member |
WO2001043643A1 (en) * | 1999-12-16 | 2001-06-21 | Alza Corporation | Device for enhancing transdermal flux of sampled agents |
US7003336B2 (en) * | 2000-02-10 | 2006-02-21 | Medtronic Minimed, Inc. | Analyte sensor method of making the same |
US6572740B2 (en) | 2000-04-13 | 2003-06-03 | Elan Pharma International Limited | Electrolytic cell |
US6565532B1 (en) | 2000-07-12 | 2003-05-20 | The Procter & Gamble Company | Microneedle apparatus used for marking skin and for dispensing semi-permanent subcutaneous makeup |
US6440096B1 (en) * | 2000-07-14 | 2002-08-27 | Becton, Dickinson And Co. | Microdevice and method of manufacturing a microdevice |
JP2002028247A (en) * | 2000-07-18 | 2002-01-29 | Japan Science & Technology Corp | Method and instrument for sensing venous pricking by puncture needle |
EP2554196B1 (en) | 2000-11-30 | 2018-10-17 | Valeritas, Inc. | Fluid delivery and measurement systems |
AU2002345757A1 (en) | 2001-06-11 | 2002-12-23 | Glaxo Group Limited | Medicament dispenser for containers of varying sizes |
US6835193B2 (en) | 2001-07-10 | 2004-12-28 | Myocardial Therapeutics, Inc. | Methods for controlled depth injections into interior body cavities |
US7429258B2 (en) | 2001-10-26 | 2008-09-30 | Massachusetts Institute Of Technology | Microneedle transport device |
WO2003059192A2 (en) * | 2001-12-21 | 2003-07-24 | The Trustees Of Columbia University In The City Of New York | C3 exoenzyme-coated stents and uses thereof for treating and preventing restenosis |
EP1403519A1 (en) * | 2002-09-27 | 2004-03-31 | Novo Nordisk A/S | Membrane pump with stretchable pump membrane |
-
2002
- 2002-09-09 US US10/238,844 patent/US7429258B2/en not_active Expired - Fee Related
- 2002-10-18 AT AT02789233T patent/ATE420680T1/en not_active IP Right Cessation
- 2002-10-18 DE DE60230896T patent/DE60230896D1/en not_active Expired - Lifetime
- 2002-10-18 CA CA2464483A patent/CA2464483C/en not_active Expired - Fee Related
- 2002-10-18 JP JP2003539742A patent/JP2005525141A/en active Pending
- 2002-10-18 EP EP02789233A patent/EP1439871B1/en not_active Expired - Lifetime
- 2002-10-18 WO PCT/US2002/033544 patent/WO2003037403A1/en active Application Filing
- 2002-10-18 AU AU2002353840A patent/AU2002353840B2/en not_active Ceased
- 2002-10-21 US US10/278,050 patent/US7066922B2/en not_active Expired - Lifetime
- 2002-10-21 CA CA2464485A patent/CA2464485C/en not_active Expired - Fee Related
- 2002-10-21 US US10/278,049 patent/US7364568B2/en not_active Expired - Fee Related
- 2002-10-21 JP JP2003539743A patent/JP4612304B2/en not_active Expired - Fee Related
- 2002-10-21 US US10/277,722 patent/US7645263B2/en not_active Expired - Fee Related
- 2002-10-21 US US10/277,724 patent/US20030083618A1/en not_active Abandoned
- 2002-10-21 AT AT02782208T patent/ATE386561T1/en not_active IP Right Cessation
- 2002-10-21 WO PCT/US2002/033794 patent/WO2003037404A1/en active IP Right Grant
- 2002-10-21 DE DE60225172T patent/DE60225172D1/en not_active Expired - Lifetime
- 2002-10-21 EP EP02782208A patent/EP1446176B1/en not_active Expired - Lifetime
- 2002-10-22 AU AU2002348009A patent/AU2002348009B9/en not_active Ceased
- 2002-10-22 EP EP02784221A patent/EP1448253B1/en not_active Expired - Lifetime
- 2002-10-22 WO PCT/US2002/033829 patent/WO2003037406A2/en not_active Application Discontinuation
- 2002-10-22 AU AU2002353855A patent/AU2002353855B2/en not_active Ceased
- 2002-10-22 EP EP02784220A patent/EP1438092A2/en not_active Withdrawn
- 2002-10-22 AT AT02784221T patent/ATE419885T1/en not_active IP Right Cessation
- 2002-10-22 CA CA2464670A patent/CA2464670C/en not_active Expired - Fee Related
- 2002-10-22 WO PCT/US2002/033823 patent/WO2003037405A1/en active Application Filing
- 2002-10-22 JP JP2003539745A patent/JP2005507715A/en active Pending
- 2002-10-22 CA CA2464673A patent/CA2464673C/en not_active Expired - Fee Related
- 2002-10-22 JP JP2003539744A patent/JP4610192B2/en not_active Expired - Fee Related
- 2002-10-22 JP JP2003539746A patent/JP4610193B2/en not_active Expired - Fee Related
- 2002-10-22 EP EP02789250A patent/EP1443990A1/en not_active Ceased
- 2002-10-22 WO PCT/US2002/033830 patent/WO2003037407A1/en active Application Filing
- 2002-10-22 CA CA002464487A patent/CA2464487A1/en not_active Abandoned
- 2002-10-22 DE DE60230795T patent/DE60230795D1/en not_active Expired - Lifetime
-
2005
- 2005-10-19 JP JP2005304325A patent/JP2006081918A/en active Pending
-
2008
- 2008-01-11 US US11/972,726 patent/US7651475B2/en not_active Expired - Fee Related
- 2008-04-29 US US12/150,606 patent/US8246582B2/en not_active Expired - Fee Related
-
2009
- 2009-05-11 JP JP2009114990A patent/JP2009240790A/en active Pending
- 2009-05-11 JP JP2009114989A patent/JP2009219886A/en active Pending
- 2009-05-11 JP JP2009114991A patent/JP2009219887A/en active Pending
- 2009-05-11 JP JP2009114992A patent/JP2009219888A/en active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR757501A (en) * | 1932-09-23 | 1933-12-28 | Automatic device for handling injection syringes | |
US3727614A (en) * | 1971-05-13 | 1973-04-17 | Merck & Co Inc | Multiple dosage inoculator |
WO1993017754A1 (en) * | 1992-03-13 | 1993-09-16 | Elan Medical Technologies Limited | Drug delivery devices |
WO1994023777A1 (en) * | 1993-04-08 | 1994-10-27 | Elan Medical Technologies Limited | Intradermal injection device |
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US10326347B2 (en) | 2005-02-11 | 2019-06-18 | Massachusetts Institute Of Technology | Controlled needle-free transport |
EP2158908B1 (en) * | 2007-06-21 | 2013-04-24 | Fujimoto Co., Ltd. | Composition for transdermal administration |
EP2158908A1 (en) * | 2007-06-21 | 2010-03-03 | Fujimoto Co., Ltd. | Composition for transdermal or transmucosal administration |
US10939860B2 (en) | 2009-03-02 | 2021-03-09 | Seventh Sense Biosystems, Inc. | Techniques and devices associated with blood sampling |
US9113836B2 (en) | 2009-03-02 | 2015-08-25 | Seventh Sense Biosystems, Inc. | Devices and techniques associated with diagnostics, therapies, and other applications, including skin-associated applications |
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US9033898B2 (en) | 2010-06-23 | 2015-05-19 | Seventh Sense Biosystems, Inc. | Sampling devices and methods involving relatively little pain |
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US8740838B2 (en) | 2010-10-07 | 2014-06-03 | Massachusetts Institute Of Technology | Injection methods using a servo-controlled needle-free injector |
US9295417B2 (en) | 2011-04-29 | 2016-03-29 | Seventh Sense Biosystems, Inc. | Systems and methods for collecting fluid from a subject |
US9119578B2 (en) | 2011-04-29 | 2015-09-01 | Seventh Sense Biosystems, Inc. | Plasma or serum production and removal of fluids under reduced pressure |
US10188335B2 (en) | 2011-04-29 | 2019-01-29 | Seventh Sense Biosystems, Inc. | Plasma or serum production and removal of fluids under reduced pressure |
US10835163B2 (en) | 2011-04-29 | 2020-11-17 | Seventh Sense Biosystems, Inc. | Systems and methods for collecting fluid from a subject |
US10543310B2 (en) | 2011-12-19 | 2020-01-28 | Seventh Sense Biosystems, Inc. | Delivering and/or receiving material with respect to a subject surface |
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