WO2003039655A3 - Delivery system and method for interstitial radiation therapy - Google Patents

Delivery system and method for interstitial radiation therapy Download PDF

Info

Publication number
WO2003039655A3
WO2003039655A3 PCT/US2002/035236 US0235236W WO03039655A3 WO 2003039655 A3 WO2003039655 A3 WO 2003039655A3 US 0235236 W US0235236 W US 0235236W WO 03039655 A3 WO03039655 A3 WO 03039655A3
Authority
WO
WIPO (PCT)
Prior art keywords
delivery system
radiation therapy
interstitial radiation
interstitial
elongated member
Prior art date
Application number
PCT/US2002/035236
Other languages
French (fr)
Other versions
WO2003039655A2 (en
Inventor
Richard A Terwilliger
Gary A Lamoureux
Original Assignee
Richard A Terwilliger
Gary A Lamoureux
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richard A Terwilliger, Gary A Lamoureux filed Critical Richard A Terwilliger
Priority to EP02776431A priority Critical patent/EP1450891B1/en
Priority to DK02776431.5T priority patent/DK1450891T3/en
Priority to ES02776431T priority patent/ES2398744T3/en
Priority to AU2002342293A priority patent/AU2002342293A1/en
Publication of WO2003039655A2 publication Critical patent/WO2003039655A2/en
Publication of WO2003039655A3 publication Critical patent/WO2003039655A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1027Interstitial radiation therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007Arrangements or means for the introduction of sources into the body
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/15Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor incorporating preformed parts or layers, e.g. extrusion moulding around inserts
    • B29C48/157Coating linked inserts, e.g. chains
    • GPHYSICS
    • G21NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21GCONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G4/00Radioactive sources
    • G21G4/04Radioactive sources other than neutron sources
    • G21G4/06Radioactive sources other than neutron sources characterised by constructional features
    • G21G4/08Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical application
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N2005/1019Sources therefor
    • A61N2005/1023Means for creating a row of seeds, e.g. spacers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N2005/1019Sources therefor
    • A61N2005/1024Seeds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/03Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the shape of the extruded material at extrusion
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C48/00Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
    • B29C48/15Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor incorporating preformed parts or layers, e.g. extrusion moulding around inserts
    • B29C48/151Coating hollow articles

Abstract

A delivery system and method for interstitial radiation therapy having a substantially axially stiff and longitudinally flexible elongated member (12) carrying radioactive seeds (14).
PCT/US2002/035236 2001-11-02 2002-11-01 Delivery system and method for interstitial radiation therapy WO2003039655A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP02776431A EP1450891B1 (en) 2001-11-02 2002-11-01 Delivery system for interstitial radiation therapy and method for manufacturing the same
DK02776431.5T DK1450891T3 (en) 2001-11-02 2002-11-01 RELEASE SYSTEM FOR INTERSTITIAL RADIATION THERAPY AND METHOD OF PRODUCING THEREOF
ES02776431T ES2398744T3 (en) 2001-11-02 2002-11-01 Administration system for insterstitial radiation therapy and method of manufacturing it
AU2002342293A AU2002342293A1 (en) 2001-11-02 2002-11-01 Delivery system and method for interstitial radiation therapy

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US33632901P 2001-11-02 2001-11-02
US60/336,329 2001-11-02
US10/035,083 US7060020B2 (en) 2001-11-02 2001-12-28 Delivery system and method for interstitial radiation therapy
US10/035,083 2001-12-28

Publications (2)

Publication Number Publication Date
WO2003039655A2 WO2003039655A2 (en) 2003-05-15
WO2003039655A3 true WO2003039655A3 (en) 2003-10-16

Family

ID=26711735

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/035236 WO2003039655A2 (en) 2001-11-02 2002-11-01 Delivery system and method for interstitial radiation therapy

Country Status (7)

Country Link
US (6) US7060020B2 (en)
EP (2) EP2462988B1 (en)
AU (1) AU2002342293A1 (en)
DK (1) DK1450891T3 (en)
ES (2) ES2440079T3 (en)
PT (1) PT1450891E (en)
WO (1) WO2003039655A2 (en)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US8088060B2 (en) 2000-03-15 2012-01-03 Orbusneich Medical, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
EP1545705A4 (en) 2000-11-16 2010-04-28 Microspherix Llc Flexible and/or elastic brachytherapy seed or strand
GB0120645D0 (en) 2001-08-24 2001-10-17 Smiths Group Plc Medico-surgical devices
US7060020B2 (en) 2001-11-02 2006-06-13 Ideamatrix, Inc. Delivery system and method for interstitial radiation therapy
US6761680B2 (en) * 2001-11-02 2004-07-13 Richard A. Terwilliger Delivery system and method for interstitial radiation therapy using seed strands constructed with preformed strand housing
US7074291B2 (en) * 2001-11-02 2006-07-11 Worldwide Medical Technologies, L.L.C. Delivery system and method for interstitial radiation therapy using strands constructed with extruded strand housings
DE10204818C2 (en) * 2002-02-06 2003-11-27 Eurotope Entwicklungsgesellsch Device and method for loading implantation needles with radiation sources from radiation source chains for interstitial brachytherapy of tissue
DE60324448D1 (en) * 2002-09-10 2008-12-11 Cianna Medical Inc brachytherapy
US6969344B2 (en) 2003-02-10 2005-11-29 Bard Brachytherapy, Inc. End portion of first implantation seed spacer that receives and holds any one of implantation seed and second implantation seed spacer
GB0307350D0 (en) 2003-03-29 2003-05-07 Smiths Group Plc Catheters
US6997862B2 (en) * 2003-05-13 2006-02-14 Ideamatrix, Inc. Delivery system and method for interstitial radiation therapy using seed strands with custom end spacing
BRPI0515007A (en) 2004-08-12 2008-07-01 Navotek Medical Ltd computerized system for tracking and tracing of irradiated ionization source, sensor for targeting located on an ionized radiation source, method for determining device location, method of locating device manufacturing, and use of ionizing radiation shield
US7361135B2 (en) * 2004-08-24 2008-04-22 C R Bard, Inc Brachytherapy system for dispensing medication
US7588528B2 (en) * 2004-08-24 2009-09-15 C. R. Bard, Inc. Brachytherapy apparatus for dispensing medication
US20080262473A1 (en) * 2004-10-19 2008-10-23 Navotek Medical Ltd. Locating a Catheter Tip Using a Tracked Guide
US7223226B2 (en) 2004-11-05 2007-05-29 Nuclear Consultants Group, Inc. Brachytherapy needle and methods for assembling same
US8187159B2 (en) 2005-07-22 2012-05-29 Biocompatibles, UK Therapeutic member including a rail used in brachytherapy and other radiation therapy
US7736293B2 (en) * 2005-07-22 2010-06-15 Biocompatibles Uk Limited Implants for use in brachytherapy and other radiation therapy that resist migration and rotation
BRPI0616514A2 (en) * 2005-08-11 2011-06-21 Navotek Medical Ltd medical treatment system and method using position sensor based radioactivity
CN101282760A (en) * 2005-08-11 2008-10-08 纳沃特克医药有限公司 Medical treatment system and method using radioactivity based position sensor
EP1922011B1 (en) * 2005-08-11 2012-05-02 Navotek Medical Ltd. Localization of a radioactive source
US7988611B2 (en) * 2006-05-09 2011-08-02 Biocompatibles Uk Limited After-loader for positioning implants for needle delivery in brachytherapy and other radiation therapy
US20090216063A1 (en) * 2008-01-29 2009-08-27 Biocompatibles Uk Limited Bio-absorbable brachytherapy strands
US20100228074A1 (en) * 2006-08-25 2010-09-09 C.R. Bard, Inc. Therapeutic and Directionally Dosed Implants
US7878964B1 (en) 2006-09-07 2011-02-01 Biocompatibles Uk Limited Echogenic spacers and strands
US7874976B1 (en) 2006-09-07 2011-01-25 Biocompatibles Uk Limited Echogenic strands and spacers therein
US20080269540A1 (en) * 2007-04-27 2008-10-30 Worldwide Medical Technologies Llc Seed cartridge adaptor and methods for use therewith
US7553264B2 (en) * 2007-05-18 2009-06-30 Tuffstuff Fitness Equipment, Inc. Push/pull exercise apparatus, device, and method
US20090054874A1 (en) * 2007-08-23 2009-02-26 C. R. Bard, Inc. Multi-lumen catheter including a lumen having a variable cross sectional area
US8221358B2 (en) * 2007-11-20 2012-07-17 Warsaw Orthopedic, Inc. Devices and methods for delivering drug depots to a site beneath the skin
JP2011510750A (en) * 2008-01-29 2011-04-07 クライマン、ギルバート・エイチ Drug delivery device, kit and methods thereof
US8061215B2 (en) * 2008-06-13 2011-11-22 Ehc Canada, Inc. Apparatus for and method of measuring tension in a handrail for an escalator or moving walkway
EP2156806A1 (en) * 2008-08-18 2010-02-24 Navotek Medical Ltd. Implantation device for soft tissue markers and other implants
US8821364B2 (en) * 2008-09-02 2014-09-02 Battelle Memorial Institute Brachytherapy seed with fast dissolving matrix for optimal delivery of radionuclides to cancer tissue
US20100056843A1 (en) * 2008-09-02 2010-03-04 Battelle Memorial Institute Brachytherapy Seed With Fast Dissolving Matrix for Optimal Delivery of Radionuclides To Cancer Tissue
US8663210B2 (en) 2009-05-13 2014-03-04 Novian Health, Inc. Methods and apparatus for performing interstitial laser therapy and interstitial brachytherapy
WO2011015958A2 (en) * 2009-08-06 2011-02-10 Koninklijke Philips Electronics N.V. Oncology therapies employing radioactive seeds
US10293553B2 (en) 2009-10-15 2019-05-21 Covidien Lp Buttress brachytherapy and integrated staple line markers for margin identification
US20150231409A1 (en) 2009-10-15 2015-08-20 Covidien Lp Buttress brachytherapy and integrated staple line markers for margin identification
EP2533737B1 (en) 2010-02-08 2014-01-08 On Demand Therapeutics, Inc. Low-permeability, laser-activated drug delivery device
WO2012024085A2 (en) 2010-08-20 2012-02-23 Wake Forest University Health Sciences Tethered and/or visually coded brachytherapy devices and related methods
FR3018196A1 (en) * 2014-03-10 2015-09-11 Andriy Bondaryev E12-ENDOSCOPIC NEEDLE I125 RADIOACTIVE SOURCE APPLICATOR FOR ENDOBRACHYTHERAPY OF MALIGNANT TUMORS
US9775978B2 (en) 2014-07-25 2017-10-03 Warsaw Orthopedic, Inc. Drug delivery device and methods having a retaining member
US9764122B2 (en) 2014-07-25 2017-09-19 Warsaw Orthopedic, Inc. Drug delivery device and methods having an occluding member
US10076650B2 (en) 2015-11-23 2018-09-18 Warsaw Orthopedic, Inc. Enhanced stylet for drug depot injector
US10159850B2 (en) 2016-01-06 2018-12-25 Covidien Lp Brachytherapy clip and applicator
USD802755S1 (en) 2016-06-23 2017-11-14 Warsaw Orthopedic, Inc. Drug pellet cartridge
US10434261B2 (en) 2016-11-08 2019-10-08 Warsaw Orthopedic, Inc. Drug pellet delivery system and method
EP3703804B1 (en) 2017-11-02 2022-02-16 IsoRay Medical, Inc. Device for loading brachytherapy seeds into implantation sleeves
FR3093908A1 (en) * 2019-03-21 2020-09-25 Surgical Radiation Products, Llc METAL MARKER BRAIDED SUTURE SYSTEM
US11224761B1 (en) 2019-11-19 2022-01-18 Pointsource Technologies, Llc Radioactive therapeutic device

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6159143A (en) * 1998-06-17 2000-12-12 Scimed Life Systems, Inc. Method and device for delivery of therapeutic agents in conjunction with isotope seed placement
US6497646B1 (en) * 2001-03-14 2002-12-24 Cordis Corporation Intravascular radiotherapy source ribbon having variable radiopacity

Family Cites Families (179)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US586099A (en) * 1897-07-13 Excavator
US470228A (en) * 1892-03-08 Car-coupling
US1578945A (en) 1923-01-08 1926-03-30 Sanford M Withers Radium needle structure
US2067589A (en) 1935-10-08 1937-01-12 Louis C Antrim Fertilizing stick
US2153889A (en) * 1937-07-20 1939-04-11 J A Deknatel & Son Inc Suture
US2575138A (en) 1948-10-29 1951-11-13 Charles E Slaughter Method and apparatus for packaging and package
US2703316A (en) 1951-06-05 1955-03-01 Du Pont Polymers of high melting lactide
US2668162A (en) 1952-03-20 1954-02-02 Du Pont Preparation of high molecular weight polyhydroxyacetic ester
US2758987A (en) 1952-06-05 1956-08-14 Du Pont Optically active homopolymers containing but one antipodal species of an alpha-monohydroxy monocarboxylic acid
US3187752A (en) * 1962-04-27 1965-06-08 American Cyanamid Co Non-absorbable silicone coated sutures and method of making
US3297033A (en) 1963-10-31 1967-01-10 American Cyanamid Co Surgical sutures
US3351049A (en) 1965-04-12 1967-11-07 Hazleton Nuclear Science Corp Therapeutic metal seed containing within a radioactive isotope disposed on a carrier and method of manufacture
US3565869A (en) 1968-12-23 1971-02-23 American Cyanamid Co Extrudable and stretchable polyglycolic acid and process for preparing same
CA927032A (en) * 1969-06-30 1973-05-22 H. Beacham Harry Flame-retardant resin compositions
BE758156R (en) 1970-05-13 1971-04-28 Ethicon Inc ABSORBABLE SUTURE ELEMENT AND ITS
US3839297A (en) 1971-11-22 1974-10-01 Ethicon Inc Use of stannous octoate catalyst in the manufacture of l(-)lactide-glycolide copolymer sutures
US3752630A (en) 1972-01-05 1973-08-14 Takagi H Apparatus for continuous production of thermoplastic synthetic resin tube with heat-shrinking property
US3811426A (en) * 1973-05-21 1974-05-21 Atomic Energy Commission Method and apparatus for the in-vessel radiation treatment of blood
US4052988A (en) 1976-01-12 1977-10-11 Ethicon, Inc. Synthetic absorbable surgical devices of poly-dioxanone
US4141087A (en) 1977-01-19 1979-02-27 Ethicon, Inc. Isomorphic copolyoxalates and sutures thereof
US4086914A (en) 1977-02-11 1978-05-02 Edwin Bailey Moore Implant injector
US4167179A (en) 1977-10-17 1979-09-11 Mark Kirsch Planar radioactive seed implanter
US4416308A (en) * 1979-11-30 1983-11-22 Bower James F Flexible one-way valve and method of producing
US4343931A (en) 1979-12-17 1982-08-10 Minnesota Mining And Manufacturing Company Synthetic absorbable surgical devices of poly(esteramides)
US4402308A (en) 1980-11-03 1983-09-06 Scott Walter P Medical implantation device
US4509506A (en) 1981-05-11 1985-04-09 Minnesota Mining & Manufacturing Co. Shielding device for radioactive seed
US4689424A (en) 1981-08-06 1987-08-25 Ethicon, Inc. Radiation sterilizable absorbable polymeric materials and methods for manufacturing the same
US4416659A (en) * 1981-11-09 1983-11-22 Eli Lilly And Company Sustained release capsule for ruminants
US4441496A (en) 1982-02-08 1984-04-10 Ethicon, Inc. Copolymers of p-dioxanone and 2,5-morpholinediones and surgical devices formed therefrom having accelerated absorption characteristics
US4452973A (en) 1982-11-12 1984-06-05 American Cyanamid Company Poly(glycolic acid)/poly(oxyethylene) triblock copolymers and method of manufacturing the same
US4510295A (en) 1983-01-20 1985-04-09 Ethicon, Inc. Absorbable polymers of substituted benzoic acid
US4473670A (en) 1983-05-25 1984-09-25 Ethicon, Inc. Salt-filled absorbable polymers
US4612923A (en) 1983-12-01 1986-09-23 Ethicon, Inc. Glass-filled, absorbable surgical devices
US4646741A (en) 1984-11-09 1987-03-03 Ethicon, Inc. Surgical fastener made from polymeric blends
US4754745A (en) 1984-11-21 1988-07-05 Horowitz Bruce S Conformable sheet material for use in brachytherapy
US4697575A (en) * 1984-11-21 1987-10-06 Henry Ford Hospital Delivery system for interstitial radiation therapy including substantially non-deflecting elongated member
US4702228A (en) 1985-01-24 1987-10-27 Theragenics Corporation X-ray-emitting interstitial implants
US4741337A (en) 1985-07-17 1988-05-03 Ethicon, Inc. Surgical fastener made from glycolide-rich polymer blends
US4759345A (en) * 1987-02-09 1988-07-26 Mistry Vitthalbhai D Radiation shielded seed loader for hand implanter hypodermic needles apparatus and method
US4772287A (en) * 1987-08-20 1988-09-20 Cedar Surgical, Inc. Prosthetic disc and method of implanting
US4847505A (en) 1987-11-02 1989-07-11 Best Industries, Inc. Storage and transport containers for radioactive medical materials
US4916209A (en) 1987-12-23 1990-04-10 Pfizer Inc. Bioabsorbable polydepsipeptide, preparation and use thereof
US4936823A (en) * 1988-05-04 1990-06-26 Triangle Research And Development Corp. Transendoscopic implant capsule
IL86549A (en) 1988-05-30 1991-04-15 Hydro Plan Eng Ltd Process and installation for producing a drip irrigation conduit
US4891165A (en) 1988-07-28 1990-01-02 Best Industries, Inc. Device and method for encapsulating radioactive materials
US4946435A (en) * 1988-10-24 1990-08-07 Best Industries, Inc. Flexible sealed radioactive film for radiotherapy, and method of making same
US5205289A (en) 1988-12-23 1993-04-27 Medical Instrumentation And Diagnostics Corporation Three-dimensional computer graphics simulation and computerized numerical optimization for dose delivery and treatment planning
AT397468B (en) 1990-07-11 1994-04-25 Oesterr Forsch Seibersdorf SPOTLIGHT HOLDER AND METHOD AND DEVICE FOR PRODUCING THE SAME
US6099457A (en) 1990-08-13 2000-08-08 Endotech, Inc. Endocurietherapy
US5242373A (en) 1991-09-17 1993-09-07 Scott Walter P Medical seed implantation instrument
US5324503A (en) * 1992-02-06 1994-06-28 Mallinckrodt Medical, Inc. Iodo-phenylated chelates for x-ray contrast
US5264540A (en) 1992-07-20 1993-11-23 Ethicon, Inc. Aromatic polyanhydrides
US5391139A (en) 1992-09-03 1995-02-21 William Beaumont Hospital Real time radiation treatment planning system
US5397816A (en) * 1992-11-17 1995-03-14 Ethicon, Inc. Reinforced absorbable polymers
US5405309A (en) 1993-04-28 1995-04-11 Theragenics Corporation X-ray emitting interstitial implants
US5460592A (en) * 1994-01-24 1995-10-24 Amersham Holdings, Inc. Apparatus and method for making carrier assembly for radioactive seed carrier
US5833593A (en) * 1995-11-09 1998-11-10 United States Surgical Corporation Flexible source wire for localized internal irradiation of tissue
US5713828A (en) 1995-11-27 1998-02-03 International Brachytherapy S.A Hollow-tube brachytherapy device
US5761877A (en) 1996-02-23 1998-06-09 Quandt; W. Gerald System for individual dosage medication distribution
GB2314274A (en) * 1996-06-20 1997-12-24 Gyrus Medical Ltd Electrode construction for an electrosurgical instrument
US5860909A (en) 1996-10-18 1999-01-19 Mick Radio Nuclear Instruments, Inc. Seed applicator for use in radiation therapy
US5755704A (en) * 1996-10-29 1998-05-26 Medtronic, Inc. Thinwall guide catheter
US6039684A (en) * 1997-12-11 2000-03-21 Allegheny University Of The Health Sciences Non-lethal conditioning methods for the treatment of acquired immunodeficiency syndrome
US6312374B1 (en) * 1997-03-06 2001-11-06 Progenix, Llc Radioactive wire placement catheter
US6216034B1 (en) * 1997-08-01 2001-04-10 Genetronics, Inc. Method of programming an array of needle electrodes for electroporation therapy of tissue
US6419621B1 (en) 1997-10-24 2002-07-16 Radiomed Corporation Coiled brachytherapy device
US6561967B2 (en) 1997-12-12 2003-05-13 Bruno Schmidt Interstitial brachytherapy device and method
US6213932B1 (en) 1997-12-12 2001-04-10 Bruno Schmidt Interstitial brachytherapy device and method
US5938583A (en) 1997-12-29 1999-08-17 Grimm; Peter D. Precision implant needle and method of using same in seed implant treatment of prostate cancer
US6540693B2 (en) 1998-03-03 2003-04-01 Senorx, Inc. Methods and apparatus for securing medical instruments to desired locations in a patients body
US6327490B1 (en) 1998-02-27 2001-12-04 Varian Medical Systems, Inc. Brachytherapy system for prostate cancer treatment with computer implemented systems and processes to facilitate pre-implantation planning and post-implantation evaluations with storage of multiple plan variations for a single patient
US6360116B1 (en) 1998-02-27 2002-03-19 Varian Medical Systems, Inc. Brachytherapy system for prostate cancer treatment with computer implemented systems and processes to facilitate pre-operative planning and post-operative evaluations
US5928130A (en) 1998-03-16 1999-07-27 Schmidt; Bruno Apparatus and method for implanting radioactive seeds in tissue
DE19815568C2 (en) * 1998-03-31 2000-06-08 Bebig Isotopentechnik Und Umwe Process for the production of medical radioactive ruthenium radiation sources by electrolytic deposition of radioactive ruthenium on a carrier, radiation sources produced with this process and electrolysis cell for producing radioactive ruthenium layers
US6010446A (en) 1998-05-20 2000-01-04 Grimm; Peter D. Spacer element for radioactive seed implant treatment of prostate cancer
US6086942A (en) 1998-05-27 2000-07-11 International Brachytherapy S.A. Fluid-jet deposition of radioactive material for brachytherapy devices
US6053858A (en) 1998-06-04 2000-04-25 Advanced Cardiovascular Systems, Inc. Radiation source
WO2000004953A2 (en) * 1998-07-20 2000-02-03 Cook Urological Inc. Brachytherapy device including an anti-static handle
JP2002524108A (en) 1998-07-28 2002-08-06 インナーダイン, インコーポレイテッド Absorbable brachytherapy and chemotherapy delivery devices and methods
US6080099A (en) 1998-08-12 2000-06-27 Syntheon, Llc Radioactive therapeutic seeds
US6007475A (en) 1998-08-12 1999-12-28 Cns Technology, Inc. Radioactive therapeutic seeds
US6387034B1 (en) * 1998-08-17 2002-05-14 Georia Tech Research Corporation Brachytherapy treatment planning method and apparatus
US20010047185A1 (en) 1998-08-22 2001-11-29 Stanley Satz Radioactivatable composition and implantable medical devices formed therefrom
IL126341A0 (en) * 1998-09-24 1999-05-09 Medirad I R T Ltd Radiation delivery devices and methods of making same
US6354989B1 (en) * 1998-10-14 2002-03-12 Terumo Kabushiki Kaisha Radiation source delivery wire and catheter assembly for radiation therapy provided with the same
US6200255B1 (en) 1998-10-30 2001-03-13 University Of Rochester Prostate implant planning engine for radiotherapy
EP1127355B1 (en) * 1998-11-06 2006-03-01 GE Healthcare Limited Products and methods for brachytherapy
US6689043B1 (en) 1998-11-06 2004-02-10 Amersham Plc Products and methods for brachytherapy
DK1131185T3 (en) 1998-11-20 2005-10-03 Amersham Health As Welding method and apparatus
US6471631B1 (en) 1998-11-27 2002-10-29 Syntheon, Llc Implantable radiation therapy device having controllable radiation emission
US6132359A (en) 1999-01-07 2000-10-17 Nycomed Amersham Plc Brachytherapy seeds
AU2815400A (en) 1999-02-25 2000-09-14 Nycomed Amersham Plc Medical tools and devices with improved ultrasound visibility
US6200258B1 (en) 1999-08-10 2001-03-13 Syntheon, Llc Radioactive therapeutic seed having selective marker configuration
US6132947A (en) 1999-03-10 2000-10-17 Eastman Kodak Company Cyan coupler, and stabilizer-containing photographic element and process
US6200256B1 (en) 1999-03-17 2001-03-13 The Trustees Of Columbia University In The City Of New York Apparatus and method to treat a disease process in a luminal structure
DE60037577T2 (en) 1999-04-09 2008-12-11 Medi Physics, Inc., Arlington Heights METHOD AND DEVICE FOR LOADING ADMINISTRATION SYSTEMS FOR BRACHYTHERAPIESEEDS
US6132677A (en) 1999-04-26 2000-10-17 Lockheed Martin Energy Research Corporation Method for making radioactive metal articles having small dimensions
US6679824B1 (en) 1999-04-28 2004-01-20 Medi-Physics, Inc. Products and methods for brachytherapy
US6482178B1 (en) * 1999-05-21 2002-11-19 Cook Urological Incorporated Localization device with anchoring barbs
WO2001003761A1 (en) 1999-07-14 2001-01-18 Novoste Corporation Radioactive source train
TW427126U (en) * 1999-07-15 2001-03-21 Wu Bo Kuen Connection structure for fixture and containing article
US6454696B1 (en) * 1999-07-23 2002-09-24 Nucletron B. V. Device and method for implanting radioactive seeds
US6595908B2 (en) 1999-07-23 2003-07-22 Nucletron B.V. Method for analyzing amount of activity
US6267718B1 (en) 1999-07-26 2001-07-31 Ethicon, Endo-Surgery, Inc. Brachytherapy seed cartridge
US6221003B1 (en) 1999-07-26 2001-04-24 Indigo Medical, Incorporated Brachytherapy cartridge including absorbable and autoclaveable spacer
US6264599B1 (en) * 1999-08-10 2001-07-24 Syntheon, Llc Radioactive therapeutic seeds having fixation structure
US6752753B1 (en) 1999-10-15 2004-06-22 Deschutes Medical Products, Inc. Brachytherapy instrument and methods
US6398709B1 (en) 1999-10-19 2002-06-04 Scimed Life Systems, Inc. Elongated member for intravascular delivery of radiation
US6264600B1 (en) 1999-10-21 2001-07-24 Peter D. Grimm Hollow suture member with radioactive seeds positioned therein for treatment of prostate cancer
US6436026B1 (en) 1999-10-22 2002-08-20 Radiomed Corporation Flexible, continuous, axially elastic interstitial brachytherapy source
US6450937B1 (en) 1999-12-17 2002-09-17 C. R. Bard, Inc. Needle for implanting brachytherapy seeds
US6575888B2 (en) 2000-01-25 2003-06-10 Biosurface Engineering Technologies, Inc. Bioabsorbable brachytherapy device
US6358195B1 (en) 2000-03-09 2002-03-19 Neoseed Technology Llc Method and apparatus for loading radioactive seeds into brachytherapy needles
US6846283B2 (en) 2000-03-09 2005-01-25 Neoseed Technology Llc Methods and apparatus for loading radioactive seeds into brachytherapy needles
US6450938B1 (en) 2000-03-21 2002-09-17 Promex, Llc Brachytherapy device
US6428504B1 (en) 2000-04-06 2002-08-06 Varian Medical Systems, Inc. Multipurpose template and needles for the delivery and monitoring of multiple minimally invasive therapies
US6438401B1 (en) * 2000-04-28 2002-08-20 Alpha Intervention Technology, Inc. Indentification and quantification of needle displacement departures from treatment plan
US6403916B1 (en) 2000-05-12 2002-06-11 Isostar International, Inc. System and automated method for producing welded end closures in thin-walled metal tubes
GB0011581D0 (en) * 2000-05-15 2000-07-05 Nycomed Amersham Plc Grooved brachytherapy
WO2001087406A2 (en) 2000-05-18 2001-11-22 Integrated Implant Systems, L.L.C. Cartridge for amedical implanting instrument
US6572525B1 (en) 2000-05-26 2003-06-03 Lisa Yoshizumi Needle having an aperture for detecting seeds or spacers loaded therein and colored seeds or spacers
US6616593B1 (en) 2000-06-05 2003-09-09 Mentor Corporation Automated radioisotope seed cartridge
US6537192B1 (en) 2000-06-05 2003-03-25 Mentor Corporation Automated radioisotope seed loader system for implant needles
US6356195B1 (en) * 2000-06-15 2002-03-12 Timex Group B.V. Anti-pilferage system
WO2002007784A2 (en) 2000-07-17 2002-01-31 Medi-Physics, Inc. CARRIER-FREE 103Pd BRACHYTHERAPY SEEDS
US6500109B2 (en) 2000-07-21 2002-12-31 Tayman Medical, Inc. Prostate treatment template
NL1016101C2 (en) 2000-09-05 2002-03-07 Nucletron Bv Row of radioactive seeds and non-radioactive spacers and connecting element therefor.
US6805898B1 (en) 2000-09-28 2004-10-19 Advanced Cardiovascular Systems, Inc. Surface features of an implantable medical device
US6554760B2 (en) 2000-10-25 2003-04-29 Gary A. Lamoureux Pre-loaded needle assembly
US6905455B2 (en) 2000-11-01 2005-06-14 Medi-Physics, Inc. Radioactive member and method of making
US6450939B1 (en) 2000-11-06 2002-09-17 Peter D. Grimm Hinged spacer element for joining radioactive seeds used in treatment of cancer
WO2002038199A2 (en) 2000-11-08 2002-05-16 Theragenics Corporation Radioactive source wire and delivery catheter for brachytherapy
US6612976B2 (en) 2000-11-13 2003-09-02 Isotech, L.L.C. Radioactive medical devices and methods of making radioactive medical devices
US6926657B1 (en) 2000-11-14 2005-08-09 Medi-Physics, Inc. Device for loading radioactive seeds
EP1545705A4 (en) 2000-11-16 2010-04-28 Microspherix Llc Flexible and/or elastic brachytherapy seed or strand
US6746661B2 (en) 2000-11-16 2004-06-08 Microspherix Llc Brachytherapy seed
US6638205B1 (en) * 2000-11-17 2003-10-28 Mds (Canada) Inc. Radioactive medical device for radiation therapy
DE10058163C2 (en) 2000-11-22 2003-07-10 Bebig Isotopen Und Medizintech Method and applicator for positioning and / or ejecting radiation sources via hollow needles into biological tissue
US6719242B2 (en) * 2000-12-01 2004-04-13 Sonoco Development, Inc. Composite core
US6472675B2 (en) 2000-12-15 2002-10-29 Theragenics Corporation Container for storing and shipping needle cartridges
US6723037B2 (en) 2000-12-15 2004-04-20 Kawasumi Laboratories, Inc. Protective tool for therapeutic material delivery device, cartridge for therapeutic material delivery device, and a therapeutic material delivery device
EP1232770A1 (en) * 2001-02-15 2002-08-21 AEA Technology QSA GmbH Radioactive capsule seed
US6800055B2 (en) * 2001-02-21 2004-10-05 Cordis Corporation Low attenuating radioactive seeds
US6572527B2 (en) 2001-02-23 2003-06-03 Mentor Corporation Radioactive seed-holding device
US6669621B2 (en) 2001-03-14 2003-12-30 Cordis Corporation Method and assembly for containing radioactive materials
US6726617B1 (en) 2001-04-09 2004-04-27 Bruno Schmidt Cartridge and applicator
US20020169354A1 (en) 2001-05-10 2002-11-14 Munro John J. Brachytherapy systems and methods
US6723052B2 (en) 2001-06-07 2004-04-20 Stanley L. Mills Echogenic medical device
US6549802B2 (en) 2001-06-07 2003-04-15 Varian Medical Systems, Inc. Seed localization system and method in ultrasound by fluoroscopy and ultrasound fusion
US8267995B2 (en) 2001-08-03 2012-09-18 David Castillejos Method and intra sclera implant for treatment of glaucoma and presbyopia
US6656106B2 (en) 2001-08-17 2003-12-02 Bruno Schmidt Device for checking seeds in brachytherapy needle
US6677496B2 (en) * 2001-08-29 2004-01-13 David Netzer Process for the coproduction of benzene from refinery sources and ethylene by steam cracking
US6755775B2 (en) 2001-08-30 2004-06-29 North American Scientific, Inc. Apparatus and method for loading a brachytherapy seed cartridge
US7060020B2 (en) * 2001-11-02 2006-06-13 Ideamatrix, Inc. Delivery system and method for interstitial radiation therapy
US7074291B2 (en) 2001-11-02 2006-07-11 Worldwide Medical Technologies, L.L.C. Delivery system and method for interstitial radiation therapy using strands constructed with extruded strand housings
US6820318B2 (en) 2001-11-02 2004-11-23 Ideamatrix, Inc. System for manufacturing interstitial radiation therapy seed strands
US6786858B2 (en) 2001-11-02 2004-09-07 Ideamatrix, Inc. Delivery system and method for interstitial radiotherapy using hollow seeds
US6639237B2 (en) 2001-11-02 2003-10-28 Mentor Corporation Brachytherapy medical devices
US6761680B2 (en) 2001-11-02 2004-07-13 Richard A. Terwilliger Delivery system and method for interstitial radiation therapy using seed strands constructed with preformed strand housing
US7094198B2 (en) 2001-11-02 2006-08-22 Worldwide Medical Technologies, Llc Delivery system and method for interstitial radiation therapy using seed elements with ends having one of projections and indentations
AU2003216103A1 (en) 2002-01-25 2003-09-02 Mick Radio-Nuclear Instruments, Inc. Disposable and shielded seed and spacer magazine
WO2003063700A1 (en) 2002-01-29 2003-08-07 Sicel Technologies, Inc. Implantable sensor housing and fabrication methods
DE10204818C2 (en) * 2002-02-06 2003-11-27 Eurotope Entwicklungsgesellsch Device and method for loading implantation needles with radiation sources from radiation source chains for interstitial brachytherapy of tissue
US20030191355A1 (en) 2002-04-04 2003-10-09 Ferguson Patrick J. Hollow bioabsorbable elements for positioning material in living tissue
US6837844B1 (en) 2002-05-14 2005-01-04 Med-Tec Iowa, Inc. Seed cartridge for radiation therapy
US6656107B1 (en) 2002-05-24 2003-12-02 Mentor Corporation Brachytherapy seed applicators
NL1020740C2 (en) 2002-06-03 2003-12-08 Nucletron Bv Method and device for the temporary introduction and placement of at least one energy-emitting source in an animal body.
DE60324448D1 (en) 2002-09-10 2008-12-11 Cianna Medical Inc brachytherapy
US20060121080A1 (en) 2002-11-13 2006-06-08 Lye Whye K Medical devices having nanoporous layers and methods for making the same
US6969344B2 (en) 2003-02-10 2005-11-29 Bard Brachytherapy, Inc. End portion of first implantation seed spacer that receives and holds any one of implantation seed and second implantation seed spacer
US20040158118A1 (en) 2003-02-10 2004-08-12 Drobnik Christopher D. Terminus-spacer component of a string comprising one or more spacer components and one or more implantation seeds
US7322928B2 (en) 2003-03-17 2008-01-29 Medi-Physics, Inc. Products and methods for brachytherapy
US20040225174A1 (en) 2003-05-06 2004-11-11 Fuller Donald B. Method for computed tomography-ultrasound interactive prostate brachytherapy
US6989543B2 (en) 2003-08-15 2006-01-24 C.R. Bard, Inc. Radiation shielding container for radioactive sources
WO2005115543A1 (en) 2004-05-20 2005-12-08 Wisconsin Alumni Research Foundation Directionally emitting radioactive sources for brachytherapy
US7425195B2 (en) 2004-08-13 2008-09-16 Core Oncology, Inc. Radiation shielding device
CN101107021A (en) 2004-12-30 2008-01-16 金文申有限公司 Combination comprising an agent providing a signal, an implant material and a drug
US8170647B2 (en) 2006-01-20 2012-05-01 Best Medical International, Inc Fiduciary markers and method of use thereof
US20070224234A1 (en) 2006-03-22 2007-09-27 Mark Steckel Medical devices having biodegradable polymeric regions

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6159143A (en) * 1998-06-17 2000-12-12 Scimed Life Systems, Inc. Method and device for delivery of therapeutic agents in conjunction with isotope seed placement
US6497646B1 (en) * 2001-03-14 2002-12-24 Cordis Corporation Intravascular radiotherapy source ribbon having variable radiopacity

Also Published As

Publication number Publication date
ES2440079T3 (en) 2014-01-27
EP1450891B1 (en) 2012-12-26
EP2462988A1 (en) 2012-06-13
US20060264688A1 (en) 2006-11-23
WO2003039655A2 (en) 2003-05-15
US7407477B2 (en) 2008-08-05
PT1450891E (en) 2013-01-31
US20030088140A1 (en) 2003-05-08
US20030171637A1 (en) 2003-09-11
US7874974B2 (en) 2011-01-25
US20100121130A1 (en) 2010-05-13
US20060069298A1 (en) 2006-03-30
US7060020B2 (en) 2006-06-13
AU2002342293A1 (en) 2003-05-19
EP1450891A2 (en) 2004-09-01
ES2398744T3 (en) 2013-03-21
US7497818B2 (en) 2009-03-03
DK1450891T3 (en) 2013-02-04
US20070191669A1 (en) 2007-08-16
US7211039B2 (en) 2007-05-01
EP2462988B1 (en) 2013-09-18
US7942803B2 (en) 2011-05-17
EP1450891A4 (en) 2009-05-27

Similar Documents

Publication Publication Date Title
WO2003039655A3 (en) Delivery system and method for interstitial radiation therapy
WO2003039463A3 (en) Hollow radioactive seeds for interstitial brachytherapy
AU2002345612A1 (en) Ultrasound-fluoroscopic seed therapy system and method
AU2001294604A1 (en) Improved radiation therapy treatment method
AU2001263349A1 (en) Radiation therapy device having controllable radiation emission
AU3357500A (en) Method for intravascular radiation therapy
WO2002037934A3 (en) Automated implantation system for radioisotope seeds
AU2654499A (en) System for locating implantable medical device
AU2002315046A1 (en) Delivery and recovery sheaths for medical devices
AU2002353943A1 (en) System for manufacturing interstitial radiation therapy seed strands
AU2002315397A1 (en) A method and system for integrated medical tracking
AU1405600A (en) A medical device comprising an evertable sleeve
AU2867499A (en) Soft x-ray emitting medical devices
AU2002367801A1 (en) Passive telemetry system for implantable medical device
AU2001259524A1 (en) A method and apparatus for radiotherapy treatment planning
AU2002254578A1 (en) Interstitial brachytherapy device and method
AU2002357351A1 (en) Implantable medical device and method for manufacturing the same
AU2002238427A1 (en) Radiotherapeutic apparatus comprising multileaf collimator
AU2320299A (en) Device and method for radiation therapy
AU2002302010A1 (en) Device for Effecting Radiation Therapy in an Animal Body
AU2001287890A1 (en) Radiotherapy apparatus and collimator set therefor
AU1371499A (en) Device for positioning a radiation source at a stenosis treatment site
AU7274598A (en) Light delivery catheter and method for the use thereof
WO2002041762A3 (en) Automated implantation system for radioisotope seeds
IL133026A0 (en) An autonomous planter and method

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2002776431

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2002776431

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP