WO2003065904A1 - Method and apparatus for attaching connective tissues to bone using a knotless suture anchoring device - Google Patents
Method and apparatus for attaching connective tissues to bone using a knotless suture anchoring device Download PDFInfo
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- WO2003065904A1 WO2003065904A1 PCT/US2002/041018 US0241018W WO03065904A1 WO 2003065904 A1 WO2003065904 A1 WO 2003065904A1 US 0241018 W US0241018 W US 0241018W WO 03065904 A1 WO03065904 A1 WO 03065904A1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0409—Instruments for applying suture anchors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0412—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors having anchoring barbs or pins extending outwardly from suture anchor body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0414—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors having a suture-receiving opening, e.g. lateral opening
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/042—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors plastically deformed during insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0427—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors having anchoring barbs or pins extending outwardly from the anchor body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0427—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors having anchoring barbs or pins extending outwardly from the anchor body
- A61B2017/0437—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors having anchoring barbs or pins extending outwardly from the anchor body the barbs being resilient or spring-like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0446—Means for attaching and blocking the suture in the suture anchor
- A61B2017/0448—Additional elements on or within the anchor
- A61B2017/0451—Cams or wedges holding the suture by friction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0446—Means for attaching and blocking the suture in the suture anchor
- A61B2017/0454—Means for attaching and blocking the suture in the suture anchor the anchor being crimped or clamped on the suture
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
- A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
- A61B2017/0446—Means for attaching and blocking the suture in the suture anchor
- A61B2017/0458—Longitudinal through hole, e.g. suture blocked by a distal suture knot
Definitions
- This invention relates generally to methods and apparatus for attaching soft tissue to bone, and more particularly to anchors and methods for securing connective tissue, such as ligaments or tendons, to bone.
- the invention has particular application to arthroscopic surgical techniques for reattaching the rotator cuff to the humeral head, in order to repair the rotator cuff.
- tear or detachment is a "rotator cuff tear, wherein the supraspinatus tendon separates from the humerus, causing pain and loss of ability to elevate and externally rotate the arm. Complete separation can occur if the shoulder is subjected to gross trauma, but typically, the tear begins as a small lesion, especially in older patients.
- the classic open approach requires a large incision and complete detachment ofthe deltoid muscle from the acromion to facilitate exposure.
- the cuff is debrided to ensure suture attachment to viable tissue and to create a reasonable edge approximation.
- the humeral head is abraded or notched at the proposed soft tissue to bone reattachment point, as healing is enhanced on a raw bone surface.
- a series of small diameter holes, referred to as "transosseous tunnels” are "punched" through the bone laterally from the abraded or notched surface to a point on the outside surface ofthe greater tuberosity, commonly a distance of 2 to 3 cm.
- the cuff is sutured and secured to the bone by pulling the suture ends through the transosseous tunnels and tying them together using the bone between two successive tunnels as a bridge, after which the deltoid muscle must be surgically reattached to the acromion. Because of this maneuver, the deltoid requires postoperative protection, thus retarding rehabilitation and possibly resulting in residual weakness. Complete rehabilitation takes approximately 9 to 12 months.
- the mini-open technique which represents the current growing trend and the majority of all surgical repair procedures, differs from the classic approach by gaining access through a smaller incision and splitting rather than detaching the deltoid. Additionally, this procedure is typically performed in conjunction with arthroscopic acromial decompression.
- the deltoid is split, it is retracted to expose the rotator cuff tear. As before, the cuff is debrided, the humeral head is abraded, and the so-called "transosseous tunnels", are "punched" through the bone or suture anchors are inserted. Following the suturing ofthe rotator cuff to the humeral head, the split deltoid is surgically repaired.
- Extracorporeal knot tying is somewhat less difficult, but the tightness ofthe knots is difficult to judge, and the tension cannot later be adjusted. Also, because ofthe use of bone anchors to provide a suture fixation point in the bone, the knots that secure the soft tissues to the anchor by necessity leave the knot bundle on top of the soft tissues. In the case of rotator cuff repair, this means that the knot bundle is left in the shoulder capsule where it can be felt by the patient postoperatively when the patient exercises the shoulder joint. So, knots tied arthroscopically are difficult to achieve, impossible to adjust, and are located in less than optimal areas ofthe shoulder. Suture tension is also impossible to measure and adjust once the knot has been fixed. Consequently, because ofthe technical difficulty of the procedure, presently less than 1% of all rotator cuff procedures is ofthe arthroscopic type, and is considered investigational in nature.
- Suture eyelets in bone anchors available today which, like the eye of a needle, are threaded with the thread or suture, are small in radius, and can cause the suture to fail at the eyelet when the anchor is placed under high tensile loads.
- the aspect ratio ofthe anchor is such that it typically has a longer axis and a shorter axis and usually is pre-threaded with a suture.
- These designs use a hole in the cortical bone through which an anchor is inserted. The hole is drilled such that the shorter axis ofthe anchor will fit through the diameter ofthe hole, with the longer axis ofthe anchor being parallel to the axis ofthe drilled hole.
- the anchor is rotated 90 ° so that the long axis is aligned perpendicularly to the axis ofthe hole.
- any ofthe anchor points for sutures mentioned above require that a length of suture be passed through an eyelet fashioned in the anchor and then looped through the soft tissues and tied down to complete the securement.
- Much skill is required, however, to both place the sutures in the soft tissues, and to tie knots while working through a trocar under endoscopic visualization.
- U.S. Patent No. 5,324,308 to Pierce there is disclosed a suture anchor that incorporates both proximal and distal wedge blocks each having inclined mating faces.
- the distal wedge block has two suture thread holes at its base through which a length of suture may be threaded.
- the assembly may be placed in a drilled hole in the bone, and when tension is placed on the suture, the distal wedge block is caused to ride up against the proximal wedge block, expanding the projected area within the drilled hole, and locking the anchor into the bone.
- the anchor member includes at least two axial compressible sections, which define a passageway to receive two end portions of a suture loop.
- the axial sections collapse radially inwardly upon insertion ofthe anchor member within the bore ofthe bead member to securely wedge the suture end portions received within the passageway.
- the Golds et al. patent approach utilizes a wedge-shaped member to lock the sutures in place, the suture legs are passing through the bore ofthe bead only one time, in a proximal to distal direction, and are locked by the collapsing ofthe wedge, which creates interference on the longitudinal bore of the anchor member. Also, no provision is made in this design for attachment of sutures to bone. The design is primarily suited for locking a suture loop, such as is used for ligation or approximation of soft tissues.
- the cavity is open to one end ofthe threaded body, and joins two lumens that run out to the other end ofthe threaded body.
- a gear journaled on an axle.
- a length of suture is threaded through one lumen, around the gear, and out through the other lumen.
- a ball is disposed within the cavity to ride against a tapered race and ostensibly lock the suture in place. What is not clear from the patent disclosure is how the force D shown as the tension in the suture would lock the ball into the race.
- this embodiment purports to be a self-locking anchor adapted for use in blind holes for fixing sutures into bone, the construct shown is complicated, and does not appear to be adequate to reliably fixate the suture.
- the present invention solves the problems outlined above by providing innovative bone anchor and connective techniques which permit a suture attachment which lies entirely beneath the cortical bone surface.
- the sutures which are passed through the tissues to be attached to bone typically are threaded through a small eyelet incorporated into the head of the anchor and then secured by tying knots in the sutures. Endoscopic knot tying is an arduous and technically demanding task. Therefore, the present invention discloses devices and methods for securing sutures to a bone anchor without the requirement of knot tying.
- a knotless suture anchor apparatus for anchoring a length of suture with respect thereto.
- the apparatus includes an anchor body having a proximal end, a distal end, and a lumen opening at the proximal end such that a length of suture may be introduced into the lumen from the proximal end.
- a plurality of suture-locking elements are located within the anchor body lumen and are each movable therewithin from respective first positions to second positions. When in their first positions the locking elements together define a generally uniform cross-section axial passage that is sized to permit axial movement ofthe length of suture therethrough. When displaced to their second positions, the cross-section ofthe axial passage converts to be irregular and therefore substantially restricts axial movement ofthe length of suture therethrough.
- the axial passage may be located generally in the center ofthe lumen, wherein the suture-locking elements each move toward the center ofthe lumen from their first to their second positions.
- the suture- locking elements are substantially C-shaped and each surrounds and defines approximately three-quarters ofthe axial passage. At least one of suture-locking elements desirably moves in a different direction than the others from their respective first to their second positions.
- a pair of suture-locking plugs may be provided that contact different suture-locking elements.
- the anchor body is sized to fit within the body cavity and has a proximal end, a distal end, and a lumen opening at the proximal end such that a length of suture may be introduced therein.
- the locking elements are radially movable within the lumen ofthe anchor body from respective first positions to second positions.
- the locking elements In their first positions, the locking elements together define a least one axial passage sized to permit axial movement ofthe length of suture therethrough. In their second positions, the locking elements reduce the size ofthe passage so as to clamp the length of suture therein and substantially restrict axial movement of the length of suture therethrough.
- the axial passage is centered in the lumen and the suture- locking elements each move radially toward the center ofthe lumen from their first to their second positions.
- the locking elements may be C-shaped, each surrounding approximately three-quarters ofthe axial passage. Desirably, at least one ofthe suture-locking elements moves in a different direction than the others.
- a pair of suture-locking plugs may be provided that, when axially displaced within the lumen, contact different suture-locking elements and move them in different directions.
- Each suture-locking plug has a first cross-sectional size and is attached to an actuation rod having a smaller cross-section, the actuation rod extending through the anchor body and to a proximal end of the apparatus to permit external manipulation ofthe suture-locking plug.
- the actuation rod may be separated from the suture-locking plug at a point of tensile weakness.
- each suture-locking element has an aperture that is offset from the center of the lumen and at least one cavity around an external edge.
- Alternating suture-locking elements have apertures that are offset in opposite directions and partially aligned to permit passage ofthe smaller sized actuation rod.
- the length of suture passes between the cavities and the inner wall ofthe anchor body. Axially displacing the actuation rod pulls the larger locking plug into the partially aligned apertures so as to radially displace the locking elements and clamp the length of suture against the inner wall ofthe anchor body.
- a method of securing soft tissue with respect to a body cavity without knots includes a step of passing a length of suture through soft tissue so that a loop of suture material is embedded in the soft tissue resulting in two free ends.
- An anchor body is provided having an open proximal end and a lumen.
- a plurality of suture-locking elements located within the anchor body lumen are each movable within the lumen from respective first positions to second positions. In their first positions, the locking elements together define a generally uniform cross-section axial passage sized to permit axial movement ofthe length of suture therethrough.
- the locking elements convert the cross- section portion ofthe axial passage to be irregular and therefore substantially restrict axial movement ofthe length of suture therethrough.
- the method includes passing the two free ends ofthe length of suture into the lumen ofthe anchor body through the open proximal end and through the passage with the suture-locking elements in their first positions. The two free ends extend out of the lumen through the open proximal end.
- the anchor body is fixed with respect to a body cavity, and the loop of suture material is tightened by pulling on one or both ofthe two free ends ofthe length of suture. Finally, two free ends ofthe length of suture are fastened with respect to the anchor body without knots by displacing the suture-locking elements to their second positions.
- the soft tissue may be a tendon, and the body cavity is formed in a bone. More particularly, the tendon is the rotator cuff tendon, and the bone is the humeral head.
- the method may further include providing a suture-locking plug that is axially displaceable within the lumen so as to contact at least some ofthe suture- locking elements and move them from their first to their second positions. Desirably, at least one ofthe suture-locking elements moves in the opposite direction to the others from their first to their second positions, and the method includes axial displacement ofthe suture-locking plug to move the suture-locking elements in opposite directions.
- the present invention also provides a method of securing soft tissue with respect to a body cavity without knots.
- the method includes passing a length of suture through soft tissue so that a loop of suture material is embedded in the soft tissue resulting in two free ends.
- An anchor body having an open proximal end and a lumen is provided.
- the two free ends of length of suture are passed into a generally axially uniform passage in the lumen ofthe anchor body through the open proximal end and wrapped around a pulley at a distal end.
- the two free ends extend through the passage and back out of lumen through the open proximal end such that there are four strands within the anchor body.
- the anchor body is fixed with respect to a body cavity, and the loop of suture material is tightened by pulling one or both ofthe two free ends ofthe length of suture that extend out ofthe proximal end ofthe anchor body. Finally, the two free ends of the length of suture are fastened with respect to the anchor body without knots by displacing a series of suture-locking elements within the anchor body to reduce the size ofthe passage and desirably convert it from uniform to irregular.
- the soft tissue may be a tendon and the body cavity may be formed in bone.
- the tendon is the rotator cuff tendon
- the bone is the humeral head.
- the step of fixing the anchor body with respect to the body cavity may include forming a body cavity, passing the anchor body therein, and radially extending an anchoring member.
- the anchoring member is located adjacent a proximal end ofthe anchor body and interferes with the cortical layer ofthe bone to prevent proximal removal ofthe anchor body from the cavity.
- the method may include providing a suture-locking plug movable within the lumen from a first position to a second position that causes displacement ofthe locking elements and compression of the two free ends of the length of suture.
- a proximal actuation rod that extends out ofthe lumen from the proximal end ofthe anchor body may be coupled to the suture-locking plug, wherein the method includes displacing the actuation rod in the proximal direction with respect to the anchor body, and desirably severing the actuation rod from the suture-locking plug after the step of compressing the suture.
- Fig. 1 A is a partial sectional view through the left shoulder of a human as seen from the front showing the use of a minimally invasive soft tissue to bone attachment system, or suture anchor system, ofthe present invention
- Fig. IB is an enlarged sectional view taken within the circle denoted IB in Fig. 1A;
- FIGs. 1C-1F are enlarged sectional views of several steps in the use ofthe suture anchor system of Fig. 1A to reattach a rotator cuff tendon;
- FIG. 2 is a perspective exploded view of a combined suture-locking portion and bone anchor structure in a distal end of an exemplary suture anchor system of the present invention;
- Fig.3 is a partially assembled elevational view ofthe distal end ofthe suture anchor system of Fig. 2;
- Fig. 4 is a plan view ofthe distal end ofthe suture anchor system of Fig. 2 in an assembled state, ready for use in the operational step of Fig. IB;
- Fig.5 is a partial longitudinal sectional view as seen in elevation ofthe distal end ofthe assembled suture anchor system of Fig. 4;
- Fig. 5 A is an end elevational view ofthe suture locking portion ofthe system of Fig. 5 taken along line 5A-5A;
- Fig. 5B is a transverse sectional view of the suture locking portion of the system of Fig. 5 taken along line 5B-5B, showing movable suture-locking elements disposed within an anchor body;
- Fig. 6 is an end elevational view of two ofthe suture-locking elements seen in Fig. 5B isolated to better illustrate their cooperative shapes;
- Fig. 7A is a perspective view of several internal components ofthe suture locking portion of the system of Fig. 2, specifically illustrating a pair of suture- locking plugs arranged for axial movement to the outside of a plurality of inter- engaging suture-locking elements shown in first positions, and four strands of suture slidable within a lumen defined by the suture-locking elements when in their first positions;
- Fig. 7B is a perspective view ofthe suture-locking portion components of Fig.7A after axial displacement ofthe suture-locking plugs which forces the suture- locking elements into second positions, thus reducing the size ofthe lumen defined therein and clamping the strands of suture;
- Figs. 7C and 7D are longitudinal sectional views of the suture locking portion ofthe system of Fig. 2 taken along the corresponding section lines in Figs. 7A and 7B;
- Fig. 8 is a partial longitudinal sectional view ofthe assembled suture anchor system similar to Fig.5, and illustrates deployment of abone anchoring member and tightening ofthe strands of suture within the system; the figure also illustrates the suture-locking plugs and elements in their positions as shown in Fig. 7A;
- Fig. 9 is a view similar to Fig. 8 after axial displacement of the suture- locking plugs have forced the suture-locking elements into their second positions, as was seen in Fig. 7B, thus clamping the strands of suture therein;
- Fig. 9A is a transverse sectional view through the suture-locking portion of the system of Fig. 9 taken along line 9A-9A;
- Fig. 10 is a partial longitudinal sectional view through an alternative suture- locking portion and bone anchor structure in a distal end of an exemplary soft tissue to bone attachment system ofthe present invention
- Fig. 11A is an end elevational view ofthe bone anchor structure of Fig. 10 taken along line 11-11;
- Fig. 1 IB is a plan view of a single bone anchor member ofthe bone anchor structure seen in Fig. 10;
- Figs. 12A and 12B are transverse sectional views through the alternative suture-locking portion seen in Fig. 10 and taken along line 12-12, respectively illustrating suture-locking elements in their first or undeployed positions and their second or deployed positions.
- the present invention provides an improved knotless suture anchor apparatus for anchoring a length of suture with respect to a body cavity.
- the apparatus is used to anchor a length of suture to a bone structure, specifically the humeral bone ofthe human shoulder.
- the length of suture is desirably looped through soft tissue, such as a rotator cuff tendon, to approximate and fix the soft tissue with respect to the body cavity (e.g., bone structure).
- the suture anchor apparatus may be utilized to secure a length of suture to body cavities other than in a bone structure, and may even be used to anchor the suture outside of a body cavity, or merely to a predetermined location within the body.
- the preferred apparatus includes an anchor body within which the length of suture may be anchored without knots. If the anchor body is to be implanted within the body cavity, structure on its exterior or coupled therewith may also be provided for securing the anchor body therein. In a preferred embodiment, the anchor body is positioned within a pre-formed cylindrical cavity in a bone structure, and a bone anchor is deployed at one end ofthe anchor body to hold it within the cavity.
- the present invention is particularly well-suited for repairing rotator cuff injuries by re-attaching the rotator cuff tendon to the outside ofthe humeral head.
- the invention permits minimally invasive surgeries on such injuries and greatly facilitates rapid and secure fixation ofthe rotator cuff tendon to the humeral head. It should be understood that the same principles described herein apply to the repair of other injuries in which soft tissue is to be re-attached to a bone structure.
- Figs. 1A-1F are cross-sectional views through the left shoulder of a human as viewed from the front and illustrate the use of an exemplary soft tissue to bone attachment system, or suture anchor system 20, for repairing a rotator cuff tendon injury.
- the rotator cuff tendon 22 is shown in its natural position overlying the bulbous humeral head 24 ofthe humerus bone 26. In rotator cuff injuries, the tendon 22 partially or completely separates from its attachment point to the humeral head 24, which point of attachment is typically located along an angled shelf, the greater tuberosity 28.
- the surgeon threads one or more sutures through the rotator cuff tendon 22 and anchors them to the greater tuberosity 28.
- the suture anchor system 20 of the present invention facilitates this latter step of anchoring the sutures to the greater tuberosity 28.
- a generally tubular trocar 30 provides a conduit through the soft tissue ofthe shoulder for passage ofthe suture anchor system 20 ofthe present invention.
- the trocar has a proximal end outside ofthe patient that the surgeon manipulates, and a distal probe or end that enters the body and through which the surgery is performed.
- the surgeon makes an incision or stab wound through the outer dermal layers of sufficient size to permit passage ofthe trocar 30 through the skin and the deltoid muscle, into proximity with the humeral head 24.
- Various trocars and techniques for creating the approach passageway are known and may be utilized with the present invention.
- more than one incision and conduit may be necessary to perform the several suturing and anchoring steps.
- the surgeon After establishing one or more direct conduits to the humeral head 24, the surgeon passes a length of suture through the soft tissue ofthe rotator cuff tendon 22 so that a loop 32 of suture material is embedded therein, as seen in Fig. IB.
- the two free ends 34a, 34b ofthe length of suture are withdrawn from the patient and coupled to the suture anchor system 20.
- the specifics of this coupling and subsequent manipulation ofthe two free ends ofthe suture will be described more fully below.
- the two free ends 34a, 34b pass into a lumen at the distal end ofthe suture anchor system 20 and, after being looped around suture anchoring structure, extend through the lumen in a proximal direction to a proximal end ofthe system to enable fixation or pulling ofthe suture ends. Therefore, the two free ends 34a, 34b are shown at the top of Fig. IB projecting from a proximal end ofthe system 20.
- the system 20 further includes a plurality of concentrically disposed cannulas or tubes as shown that perform the knotless suture anchoring operation. The interrelationship and functioning of these tubes will also be more fully explained below.
- the exemplary suture anchor system 20 as illustrated is particularly suitable for anchoring a suture to a body cavity, specifically the humeral head 24 as shown.
- a conventional technique is to first form a blind hole or cavity 40 through the cortical layer 42 and into the soft cancellous matter 44, as seen in Figs. IB and lC.
- the surgeon positions a suture anchor 46 within the cavity 40 and secures it therein to prevent removal from the cavity.
- the suture anchor 46 performs two functions: anchoring itself within the body cavity and anchoring the sutures therein. In the embodiment as illustrated in Figs. 1C and ID, the former function is accomplished using an expandable anchoring member 48 located at the proximal end ofthe suture anchor 46.
- the anchoring member 48 functions like a toggle bolt used in ceiling fixtures, and specifically expands to a larger dimension in the cavity 40 beyond the hard cortical bone 42.
- Fig. ID shows the anchoring member 48 after having been radially expanded from proximal movement ofthe suture anchor 46 (compare to the axial location ofthe suture anchor in Fig. 1C). In this manner, the suture anchor 46 is prevented from being removed from the cavity 40 once the anchoring member 48 is deployed.
- the present invention illustrates a particular anchoring member 48, although any similar expedient will work.
- a different toggle-like anchoring member may be used such as shown in co-pending application Serial Number 09/876, 488 filed on March 2, 2001, expressly incorporated by reference herein.
- an anchoring structure that expands into contact with the cancellous matter 44 or a body resembling a screw may also be used.
- the present invention is not considered to be limited by the particular anchoring structure that secures the suture locking portion to the bone or other body cavity.
- the second function ofthe suture anchor 46 is the anchoring or fixation of the suture with respect to the suture anchor itself, without the use of knots.
- the particular manner of anchoring the suture with respect to the suture anchor 46 permits easy adjustment ofthe length of suture between the suture anchor 46 and the loop 32 formed in the soft tissue prior to anchoring the suture. This adjustment allows the surgeon to establish the proper tension in the length of suture for effective repair ofthe soft tissue, and reattachment ofthe rotator cuff tendon 22 in the illustrated embodiment.
- Fig. ID also illustrates the two free ends 34a, 34b ofthe length of suture having been pulled taught prior to securing within the suture anchor 46 (see comparison with Fig. 1C).
- Fig. IE shows the fully deployed suture anchor 46 after the free ends 34a, 34b have been placed in tension and locked within the suture anchor.
- the step of locking the length of suture within the suture anchor 46 is desirably accomplished by proximal displacement of a pair of suture-locking plugs, which are connected to actuation rods or pull wires.
- the movement arrows 49 indicate this displacement, and the specifics ofthe locking structure will become clear below.
- the present invention enables the length of suture to be anchored without altering the proper tension.
- the remaining steps in the procedure involve withdrawing the concentric tubes from the surgical site as seen in Fig. IF and severing the free ends 34a 1 , 34b' close to the suture anchor 46. It should be noted that no portion ofthe suture anchor 46 or sutures 34a', 34b 1 projects above the outer surface ofthe humeral head 24, and in addition no knots are left to irritate the patient.
- Figs. 1-6 are various views illustrating a distal end ofthe exemplary suture anchor system 20 ofthe present invention.
- the several components ofthe system are seen exploded in Figure 2 and can be grouped as the suture anchor 46, the bone anchoring member 48, and a delivery system 50.
- the right side will be referenced as the proximal side and the left side as the distal side.
- the suture anchor 46 and anchoring member 48 several concentrically disposed tubes comprising the delivery system 50 will be described.
- An inner delivery tube 52 slides within an introducer tube 56 that has a shoulder 54.
- the introducer tube 56 may include a valve (not shown) on a proximal end to prevent fluid leakage therefrom. Alternatively, such a fluid leakage valve may be provided on the proximal end ofthe trocar 30 seen in Fig. 1 A.
- the concentric tubes 52, 56 ofthe suture anchor system 20 are relatively axially movable to deploy the suture anchor 46.
- Various means are known to relatively displace concentric tubes a predetermined distance and/or with a predetermined displacement force.
- the concentric tubes may extend out ofthe trocar 30 to an actuation device in the form of concentric syringe bodies/finger tabs.
- the concentric tubes may be attached to relatively movable parts in a gun-type handle, and actuated by triggers or other such levers. It is to be understood therefore that the present invention is not limited by the particular actuation device on its proximal end, and no further description in this regard will be provided.
- the suture anchor 46 includes a generally tubular anchor body 60, two series of suture-locking elements 62a, 62b, a distal end cap 64, a proximal end cap 66, and a pair of suture-locking plugs 68a, 68b.
- each ofthe suture- locking plugs 68a, 68b has an actuation rod 70 removably attached to a proximal end, that extends proximally within the delivery tube 52 and eventually projects from the proximal end ofthe suture anchor system 20, as seen in Fig. IE.
- the components ofthe suture anchor 46 are shown assembled in Fig. 3, and again in Fig. 4 as assembled with the other components ofthe suture anchor system 20.
- the end caps 64, 66 have stepped extensions that fit closely within the inner diameter ofthe tubular anchor body 60 such that the outer surfaces of these three elements define a smooth outer cylinder.
- the thus assembled anchor body 60 and end caps 64, 66 define a tube having a lumen (not numbered) opening at proximal and distal ends.
- the end caps 64, 66 axially retain the suture-locking elements 62a, 62b within the anchor body 60.
- these elements 62a, 62b cooperate to secure a length of suture within the anchor 46 by relative radial movement, and are stacked closely yet with negligible compression so as to enable relative movement.
- the close stacking of these elements 62a, 62b and presence ofthe end caps 64, 66 prevent relative axial movement therebetween.
- two diametrically opposed bores 71 in the distal end cap 64 receive and align the locking plugs 68, while two smaller diametrically opposed bores 73 in the proximal end cap 66 receive and align the actuation rods 70.
- the bone anchoring member 48 is seen in perspective in Fig. 2, and in elevation in Fig. 3.
- the tubular anchoring member 48 is exemplary only, and other structures may be utilized.
- the anchoring member 48 illustrated is a separate element disconnected from the suture anchor 46.
- an anchoring member that is formed integrally with, or connected to, the suture anchor 46 may be used.
- the bone anchoring member 48 includes a pair of wings 72a, 72b that are connected by a pair of deformable strips 74.
- the wings 72a, 72b are shown in their undeployed, unexpanded states in Figs. 2 and 3, wherein they, along with the strips 74, define something of a U-shape in elevation.
- the wings 72a, 72b are ultimately deployed outwardly with respect to each other such that the strips 74 assume a relatively linear shape, aligned with a proximal surface ofthe wings. This outward deployment is indicated by the arrows 76 in Fig. 3. A pair of stop surfaces 78 ultimately contact and limit this outward deployment, as seen in Fig. 8.
- the exemplary bone anchoring member 48 is located between the suture anchor 46 and the delivery tube 52.
- the U-shaped proximal surface ofthe member 48 conforms and is rotationally fixed with respect to a blunt distal tip 80 ofthe delivery tube 52.
- corners ofthe distal stop surfaces 78 contact the proximal end cap 66 ofthe suture anchor 46.
- the bone anchoring member 48 defines a lumen 82 therethrough, as seen in Fig. 2.
- the actuation rods 70 pass through the hollow suture anchor 46, through the lumen 82, and through a passage 84 in the delivery tube 52, to the proximal end ofthe trocar 30 (Fig. 1A).
- tension on the actuation rods 70 maintains the suture anchor 46 and bone anchoring member 48 together and held against the blunt distal tip 80 ofthe delivery tube 52, as in Fig. 4. Even after removal ofthe delivery tube 52 and actuation rods 70, as seen in Fig. IF, the suture anchor 46 and bone anchoring member 48 remain held together under the tension ofthe two free ends 34a, 34b ofthe length of suture.
- Fig. 4 shows the suture loop 32 extending transversely from within an axial slot 86 ofthe delivery tube 52.
- both the intermediate tube 54 and introducer tube 56 are also provided with axial slots 88, 90, respectively.
- the slots 86, 88, 90 align and permit lateral passage ofthe two free ends 34a, 34b ofthe length of suture into the passage 84 in the delivery tube 52, and from there through the bone anchoring member lumen 82 and into the suture anchor lumen to be anchored.
- Fig. IB there is shown the entrance ofthe two free ends 34a, 34b ofthe length of suture into the aligned slots in the suture anchor system 20.
- the loop 32 is first embedded in the rotator cuff tendon 22 and then the two free ends 34a, 34b can be withdrawn from the body and inserted into the system 20.
- the suture anchor 46 is then fixed in the humeral head 24 and the suture anchored therewithin.
- the aligned slots 86, 88, 90 (Fig. 2) in the system
- the two free ends 34a, 34b ofthe length of suture pass in a distal direction through the bone-anchoring member lumen 82 and into the lumen ofthe suture anchor 46.
- the two ends 34a, 34b pass completely through the suture anchor 46 and loop around a cross member 92 in the distal end cap 64 (see Figs. 2 and 5A).
- the free ends 34a, 34b return in a proximal direction back through the lumen ofthe suture anchor 46 and the bone anchoring member lumen 82.
- the suture anchor 46 there are four separate strands ofthe two free ends 34a, 34b ofthe length of suture, as can be seen in the cross-section of Fig. 5B. At the location ofthe aligned slots 86, 88, 90, the four strands separate and the two free ends 34a 1 , 34b' continue in a proximal direction to the proximal end ofthe system 20.
- Fig. 5B shows the shape of one ofthe first series of suture-locking elements 62a overlying one of the second series of suture-locking elements 62b, and both surrounding the four strands ofthe two free ends 34a, 34b ofthe length of suture.
- the elements 62a, 62b are shown in their undeployed, first positions.
- the interior edges ofthe suture-locking elements 62a, 62b define a generally round passage 94 within which the strands ofthe length of suture are constrained.
- the passage 94 has a generally uniform axial cross-section, meaning that the majority ofthe cross- section ofthe internal passage is relatively smooth axially. Therefore, the shape ofthe passage 94 is generally as seen in Figs. 5B and 6 along the entire axial stack of elements 62a, 62b.
- Each suture-locking element 62a, 62b is substantially C-shaped and surrounds and defines (at its level within the anchor body lumen) at least three- quarters ofthe axial passage 94.
- each element 62a (and each element 62b) has a central bridge portion 96 and a pair of arcuate arms 98a, 98b.
- the passage 94 is defined by the inner edges ofthe bridge portion 96 and arms 98a, 98b, and the profile is generally round except for an inward bulge 100 at the bridge portion.
- Each ofthe arms 98a, 98b terminates at points that are spaced apart a distance corresponding to a circumferential arc around the passage 94 of less than 45°, and preferably about 30°.
- the elements 62a, 62b in the two series are stacked in an alternating fashion, so that each element in the first series of elements 62a is surrounded by two elements in the second series of elements 62b, and visa versa (except, of course, for those on the stack ends).
- the alternating elements 62a, 62b are oppositely oriented 180° about the axis such that the spaced-apart ends of each element 62a align with the inward bulge 100 at the bridge portion 96 of each adjacent element 62b. This can be seen in Fig. 6 at the top and bottom. Because there is a space between the ends ofthe arms 98a, 98b, a slight non-uniformity in the inner wall ofthe passage 94 is created.
- Fig. 6 illustrates an arc ⁇ on one side ofthe two series of elements 62a, 62b that corresponds to the portion ofthe passage 94 on that side that is entirely uniform (i.e., smooth) when the elements are in their first positions.
- each ofthe first series of elements 62a is generally round, and in combination with the outer edges of the second series of elements 62b, defines a cylinder that fits closely within the tubular anchor body 60, as seen in Fig. 5B.
- Each ofthe elements 62a, 62b defines a substantially semi-circular cavity 102 in its outer edge at the location ofthe bridge portion 96.
- the cavities 102 in the first series of elements 62a are diametrically opposed from the cavities in the second series of elements 62b.
- the series of aligned cavities 102 on both sides ofthe suture anchor 46 creates tunnels through which an actuation rod 70 passes, when the suture anchor 46 is assembled, and prior to actuation thereof.
- FIG. 5B illustrates the relative sizes ofthe actuation rods 70 and the larger diameter suture-locking plugs 68a, 68b.
- Fig. 5B illustrates the relative sizes ofthe actuation rods 70 and the larger diameter suture-locking plugs 68a, 68b.
- Figs. 7A and 7B show the suture-locking elements 62a, 62b and suture- locking plugs 68a, 68b isolated to better illustrate their interaction and the advantageous mechanism for anchoring one or more lengths of suture without knots.
- Fig. 7A shows the elements 62a, 62b in their undeployed relationship, as previously illustrated in Figs. 5-6, while Fig. 7B shows the deployed state.
- Fig. 7C is a cross-section through the bridge portions 96 of each element 62a, 62b in their first positions.
- Deployment involves axial movement ofthe suture-locking plugs 68a, 68b in the direction of arrows 110 which causes radial movement ofthe suture- locking elements 62a, 62b.
- Each suture-locking plug 68a, 68b has a proximal taper 112 that initially resides adjacent the distal-most suture-locking element 62a or 62b.
- Proximal movement in the direction of arrows 110 ofthe actuation rods 70 pulls the tapers 112 and then the suture-locking plugs 68a, 68b into the aligned series of cavities 102 defined on the outer edges ofthe suture-locking elements
- Radially inward movement ofthe suture-locking elements 62a, 62b from first positions to second positions converts the cross-section ofthe axial passage 94 from generally uniform to irregular, and therefore substantially restricts axial movement ofthe lengths of suture 34a, 34b that are disposed therein.
- the irregularity can be seen in the cross-section of Fig. 7D and generally comprises alternating misaligned bulges 100 or "teeth" that compress the lengths of suture 34a, 34b from opposite sides. Because the bulges 100 are misaligned, the effect is an irregular compression ofthe lengths of suture 34a, 34b that creates significantly more frictional resistance to suture pull-through, than if the bulges were aligned.
- suture-locking elements 62a, 62b are initially disposed in first positions that together define the axial passage 94 sized to permit axial movement ofthe lengths of suture 34a, 34b therethrough.
- Axial movement ofthe suture-locking plugs 68a, 68b into the tunnels created by the cavities 102 cams the elements 62a, 62b inward toward the center ofthe anchor body lumen into second positions that, taken as an aggregate, reduce the size ofthe passage 94.
- the reduced passage 94 clamps the lengths of suture 34a, 34b therein and substantially restricts their axial movement therethrough.
- the suture-locking elements 62a, 62b are dimensioned to compress or
- the pull force is in a range that would exceed the USP (United States Pharmacopeia) Standard knot pull strength (USP 24) of the suture used.
- USP 24 Standard knot pull strength
- this knot pull strength is approximately 3.5 Kgf. In practice, however, the knot pull strength of commercially available #2 braided polyester sutures approaches 14 Kgf.
- the suture-locking elements 62a, 62b may differ from that shown.
- the elements may not be oriented in radial planes and be displaced radially, but instead may be angled and be displaced at an angle.
- the elements may be arranged to rotate in one or more directions upon axial translation ofthe locking plugs 68a, 68b, thus creating the meshing teeth, so to speak, that grip the suture strands.
- there may be only one series of elements that displace in one direction, thus crushing the suture strands against the inner wall ofthe tubular anchor body 60 or against a fixed structure within.
- the elements 62a, 62b disclosed are exemplary only, and others are contemplated.
- the materials used in the system 20 are surgical grade metals or polymers.
- the implantable suture anchor 46 and bone anchoring element 48 may be made of a biocompatible polymer such as polyethylene or a metal such as titanium.
- the suture locking elements 62a, 62b are desirably metal, although certain hard plastics or polycarbonates may be used.
- the materials ofthe devices used to implant the anchor 46, such as insertion tubes 52, 56, need not be as durable as the implantable materials.
- the anchors may also be fabricated from bio-absorbable materials commonly used for implantation such as polyglycolide (PGA), polylactide (PLA), homopolymer of 1-lactide (LPLA), or other bio- absorbable materials known in the art.
- the various components as described above are first procured and assembled.
- the surgeon creates the operating ports necessary in the dermal layers and forms the body cavity 40 in the humeral head 24 as seen in figures 1 A and IB.
- the hole 40 has been drilled in the bone at the location chosen by the surgeon for anchor fixation.
- the delivery system 50 is inserted through one ofthe operating ports, and the shoulder 54 ofthe introducer tube 56 is positioned within the hole 40.
- the anchor 46 is forced out ofthe introducer tube 46 and down into the hole 40.
- the shoulder 54 ofthe introducer tube 46 ensures that the anchor 46 is delivered into the hole 40 below the hard outer layer of cortical bone 42 so that the anchoring member 48 can bear upon the cortical bone 42.
- Figs. 8 and 9 further illustrate the suture-locking function ofthe present invention along longitudinal sections, and also show the entire bone anchoring and suture-tightening aspects.
- the suture loop 32 can be considered to be embedded in soft tissue, and thus relatively securely positioned.
- the bone anchoring member 48 has been deployed such that its flat proximal surface abuts the inside wall of a body cavity, such as the inside wall ofthe hard cortical bone 42 ofthe humeral head 24, as previously described.
- the suture anchor system 20 including the delivery tube 52 remains in place held against the bone anchoring member 48 by the locking plugs 68a, 68b and the tension in the actuation rods 70. Because the locking plugs 68a, 68b remain in their distal position, the suture-locking elements 62a, 62b are un- deployed in their first positions and the lengths of suture 34a, 34b are free to slide within the passage 94. At this stage, the surgeon adjusts the tension in the lengths of suture 34a, 34b by pulling on the free ends 34a', 34b', or pulling on one end while holding one fixed, in the direction of arrow 120 in Fig. 8.
- Adjustment ofthe length ofthe suture between the suture anchor 46 and the loop 32 is very important to ensure proper fixation ofthe rotator cuff tendon 22 with respect to the humeral head 24. If the suture is pulled too tightly, the rotator cuff tendon 22 may be unduly stressed, and the loop 32 may even pull free from the tendon. On the other hand, if the suture is too loose, the goal of reattaching the tendon 22 in its proper location will be compromised. As mentioned above, the lengths of suture 34a, 34b wrap around the cross member 92 (see Fig. 5 A) which acts as a pulley of sorts and permits the sutures to freely slide therepast.
- the result of pulling on the free ends 34a', 34b' is to pull the portions between the system 20 and the loop 32 taught. This is also depicted in Fig. ID.
- the particular tension established in the sutures 34a, 34b depends on the patient characteristics, the type of soft tissue being reattached, and surgeon judgement.
- actuation rods 70 are displaced in a proximal direction, as indicated at 122 in Fig. 9. As described above, this step causes the suture-locking elements 62a, 62b to cam inward and reduce the size ofthe passage, clamping the sutures 34a, 34b in between an irregular pattern of "teeth.”
- the cross sectional view of Fig. 9 A shows the resulting clamped configuration ofthe sutures 34a, 34b.
- One advantage provided by the present invention is the ability to tighten a suture loop embedded within soft tissue to a predetermined tension, and then lock the suture within a suture anchor without even slightly altering that tension.
- suture-locking elements 62a, 62b are displaced radially, they do not urge the sutures 34a, 34b to migrate axially within the tubular anchor body 60, and therefore do not change the length on either side ofthe cross member 92. This ensures that the proper tension established between the suture anchor 46 and the loop 32 embedded in the soft tissue does not change.
- the actuation rods 70 are detached from the suture-lockmg plugs 68a, 68b by further pulling in the direction of arrows 122, thus causing a point of weakness to sever.
- the point of weakness is not shown, but typically comprises a narrow neck or frangible point on each rod 70 disposed just proximal to, or within a bore of, the corresponding locking plug 68a or 68b.
- the concentric tubes 52, 54, 56 can be removed from the operation site and the sutures 34a, 34b severed close to the bore 82 ofthe bone anchoring member 48. After any further post-procedure steps, the site of he operation can then be closed.
- FIG. 11-12B The distal end of an alternative bone anchoring and suture locking system 130 is shown in Figs. 11-12B and includes a tubular anchor body 132 housing a plurality of identical suture-locking elements 134.
- Fig. 11 also shows the two free ends of a length of suture 136 extending through the anchor body 132 on one side and wrapping around at a distal loops 138 to continue through the body on the opposite side.
- the cross-sectional view in Fig. 12A illustrates the location of the four strands ofthe suture 136.
- the distal loops 138 wrap around a cross member or pulley fixed with respect to the anchor body 132, as in the earlier-described embodiment.
- a suture-locking plug 140 attached to an actuation rod 142 is initially located at the distal end ofthe stack of suture-locking elements 134.
- the actuation rod 142 passes through a partially aligned series of central apertures 144 in the suture-locking elements 134, as seen in Fig. 12A.
- there is a single shape of element 134 having a central aperture 144 that is offset from but overlapping the central axis.
- Adjacent elements 134 are oriented in opposite directions so that their apertures 144 are offset in opposite directions.
- the aligned portions ofthe apertures 144 are large enough for passage ofthe actuation rod 142, though smaller than the locking plug 140.
- each element 134 is initially in first positions as seen in Fig. 12A.
- the outer edge of each element 134 has two diametrically- opposed cavities 146 that are sized to receive two ofthe suture strands 136.
- the cavities 146 form axially-uniform tunnels with the inner wall ofthe tubular anchor body 132 that permit the free ends ofthe sutures to pass easily therethrough, and thus facilitate the suture tensioning step as explained above.
- the tunnels have the an entirely uniform cross- section along their axial length, as seen in Fig. 12A.
- Proximal displacement ofthe actuation rod 142 and attached locking plug 140 forces a taper at the leading or proximal end ofthe locking plug into the partially aligned apertures 144, thus camming alternating elements 134 in opposite radial directions into second positions. That is, the locking plug 140 lies on the central axis ofthe system, and thus each offset aperture 144 is forced toward the axis as well. The size of each aperture 144 is just large enough to permit passage ofthe locking plug 140, and thus the final configuration as seen in Fig. 12B has the apertures 144 aligned concentrically about the locking plug along the central axis. Fig. 12B also shows the clamping ofthe lengths of suture by the outward movement of each suture-locking element 134.
- each pair of two strands of suture is compressed against the inner wall ofthe tubular anchor body 132 by a series of spaced apart edges of the cavities 146 of every second element 134.
- FIGS 11-1 IB also show an alternative bone anchoring structure.
- the system 130 has a plurality of relatively thin bone anchoring members 150 that are stacked axially together.
- This bone anchoring system is described in co-pending application serial number 09/876,260 filed June 6, 2001, which has already been expressly incorporated by reference herein.
- Each member 150 has a V-shape prior to deployment, as seen in Fig. 11, and has a generally oval outer profile as seen in plan view in Fig. 1 IB.
- Two off-center apertures 152 in each member 150 permit passage ofthe strands of suture.
- a central aperture 154 permits passage of the actuation rod 142.
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
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AU2002358268A AU2002358268B2 (en) | 2002-02-04 | 2002-12-19 | Method and apparatus for attaching connective tissues to bone using a knotless suture anchoring device |
EP02792506.4A EP1471832B1 (en) | 2002-02-04 | 2002-12-19 | Apparatus for attaching connective tissues to bone using a knotless suture anchoring device |
JP2003565334A JP4263619B2 (en) | 2002-02-04 | 2002-12-19 | Device for attaching connective tissue to bone using a suturelessly secured suture |
CA2474378A CA2474378C (en) | 2002-02-04 | 2002-12-19 | Method and apparatus for attaching connective tissues to bone using a knotless suture anchoring device |
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US10/067,164 US6855157B2 (en) | 2002-02-04 | 2002-02-04 | Method and apparatus for attaching connective tissues to bone using a knotless suture anchoring device |
US10/067,164 | 2002-02-04 |
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WO2003065904A1 true WO2003065904A1 (en) | 2003-08-14 |
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Also Published As
Publication number | Publication date |
---|---|
US20050240226A1 (en) | 2005-10-27 |
EP1471832A4 (en) | 2010-04-21 |
EP1471832A1 (en) | 2004-11-03 |
EP1471832B1 (en) | 2016-09-07 |
US7637926B2 (en) | 2009-12-29 |
JP4263619B2 (en) | 2009-05-13 |
US6855157B2 (en) | 2005-02-15 |
US20030149448A1 (en) | 2003-08-07 |
CA2474378C (en) | 2010-07-13 |
CA2474378A1 (en) | 2003-08-14 |
AU2002358268B2 (en) | 2008-05-15 |
AU2002358268A1 (en) | 2003-09-02 |
JP2005516661A (en) | 2005-06-09 |
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