WO2003067214A3 - Method and apparatus for obtaining molecular data from a pharmaceutical specimen - Google Patents

Method and apparatus for obtaining molecular data from a pharmaceutical specimen Download PDF

Info

Publication number
WO2003067214A3
WO2003067214A3 PCT/US2003/003015 US0303015W WO03067214A3 WO 2003067214 A3 WO2003067214 A3 WO 2003067214A3 US 0303015 W US0303015 W US 0303015W WO 03067214 A3 WO03067214 A3 WO 03067214A3
Authority
WO
WIPO (PCT)
Prior art keywords
molecular data
obtaining molecular
pharmaceutical
pharmaceutical specimen
specimen
Prior art date
Application number
PCT/US2003/003015
Other languages
French (fr)
Other versions
WO2003067214A2 (en
Inventor
Richard David Bruce
Original Assignee
Ortho Mcneil Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharmaceutical Co filed Critical Ortho Mcneil Pharmaceutical Co
Priority to CA2475233A priority Critical patent/CA2475233C/en
Priority to EP03708927A priority patent/EP1485687A4/en
Priority to MXPA04008549A priority patent/MXPA04008549A/en
Priority to AU2003212885A priority patent/AU2003212885C1/en
Publication of WO2003067214A2 publication Critical patent/WO2003067214A2/en
Publication of WO2003067214A3 publication Critical patent/WO2003067214A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/653—Coherent methods [CARS]
    • G01N2021/656—Raman microprobe
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/849—Manufacture, treatment, or detection of nanostructure with scanning probe
    • Y10S977/852—Manufacture, treatment, or detection of nanostructure with scanning probe for detection of specific nanostructure sample or nanostructure-related property
    • Y10S977/853—Biological sample
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/88—Manufacture, treatment, or detection of nanostructure with arrangement, process, or apparatus for testing
    • Y10S977/881—Microscopy or spectroscopy, e.g. sem, tem

Abstract

This invention relates to a method and apparatus (7) for the analysis of pharmaceutical specimens by nondestructively obtaining the molecular data for a chemical component on the surface or within the matrix of a pharmaceutical specimen (3).
PCT/US2003/003015 2002-02-04 2003-01-31 Method and apparatus for obtaining molecular data from a pharmaceutical specimen WO2003067214A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA2475233A CA2475233C (en) 2002-02-04 2003-01-31 Method and apparatus for obtaining molecular data from a pharmaceutical specimen
EP03708927A EP1485687A4 (en) 2002-02-04 2003-01-31 Method and apparatus for obtaining molecular data from a pharmaceutical specimen
MXPA04008549A MXPA04008549A (en) 2002-02-04 2003-01-31 Method and apparatus for obtaining molecular data from a pharmaceutical specimen.
AU2003212885A AU2003212885C1 (en) 2002-02-04 2003-01-31 Method and apparatus for obtaining molecular data from a pharmaceutical specimen

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US35425202P 2002-02-04 2002-02-04
US60/354,252 2002-02-04
US10/000,000 2002-09-23
US10/339,584 US6654118B2 (en) 2002-02-04 2003-01-09 Method and apparatus for obtaining molecular data from a pharmaceutical specimen

Publications (2)

Publication Number Publication Date
WO2003067214A2 WO2003067214A2 (en) 2003-08-14
WO2003067214A3 true WO2003067214A3 (en) 2003-10-16

Family

ID=27668917

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/003015 WO2003067214A2 (en) 2002-02-04 2003-01-31 Method and apparatus for obtaining molecular data from a pharmaceutical specimen

Country Status (5)

Country Link
US (1) US6654118B2 (en)
AU (1) AU2003212885C1 (en)
CA (1) CA2475233C (en)
MX (1) MXPA04008549A (en)
WO (1) WO2003067214A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7993585B2 (en) * 2005-07-14 2011-08-09 Battelle Memorial Institute Biological and chemical monitoring
US20100294927A1 (en) * 2005-09-12 2010-11-25 Nanolnk, Inc. High throughput inspecting
GB0606891D0 (en) * 2006-04-05 2006-05-17 Council Cent Lab Res Councils Raman Analysis Of Pharmaceutical Tablets
EP2106536B1 (en) * 2007-01-05 2015-08-12 Malvern Instruments Incorporated Spectrometric investigation of heterogeneity
DE102009015341A1 (en) * 2009-03-27 2010-10-07 Carl Zeiss Ag Method for optical testing of sample during e.g. chemical analysis, involves detecting optical emission of sample depending on characteristic modulation i.e. temporally periodic modulation, of particle beam
EP2824445B1 (en) 2013-07-08 2016-03-02 Fei Company Charged-particle microscopy combined with raman spectroscopy
GB201503911D0 (en) 2015-03-09 2015-04-22 Renishaw Plc Transmission raman spectroscopy
US10365229B2 (en) * 2015-12-31 2019-07-30 Kaiser Optical Systems, Inc. Real-time characterization of pharmaceutical tablet coatings using Raman spectroscopy

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5706083A (en) * 1995-12-21 1998-01-06 Shimadzu Corporation Spectrophotometer and its application to a colorimeter
US6067154A (en) * 1998-10-23 2000-05-23 Advanced Micro Devices, Inc. Method and apparatus for the molecular identification of defects in semiconductor manufacturing using a radiation scattering technique such as raman spectroscopy
US6069690A (en) * 1998-11-13 2000-05-30 Uniphase Corporation Integrated laser imaging and spectral analysis system

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3037983C2 (en) * 1980-10-08 1983-03-31 Fa. Carl Zeiss, 7920 Heidenheim Method and device for the light-induced scanning microscopic representation of sample parameters in their spatial distribution
FR2596863B1 (en) * 1986-04-07 1988-06-17 Centre Nat Rech Scient ANALYTICAL MICROSCOPY DEVICE CAPABLE OF FORMING BOTH A RAMAN PROBE AND AN ELECTRONIC PROBE
US5923430A (en) * 1993-06-17 1999-07-13 Ultrapointe Corporation Method for characterizing defects on semiconductor wafers
NL9400111A (en) * 1994-01-24 1995-09-01 Biomat Res Group Stichting Azl Electron microscope with Raman spectroscopy.
JP3258821B2 (en) * 1994-06-02 2002-02-18 三菱電機株式会社 Method for positioning and analyzing minute foreign matter, analyzer used for the method, and method for manufacturing semiconductor element or liquid crystal display element using the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5706083A (en) * 1995-12-21 1998-01-06 Shimadzu Corporation Spectrophotometer and its application to a colorimeter
US6067154A (en) * 1998-10-23 2000-05-23 Advanced Micro Devices, Inc. Method and apparatus for the molecular identification of defects in semiconductor manufacturing using a radiation scattering technique such as raman spectroscopy
US6069690A (en) * 1998-11-13 2000-05-30 Uniphase Corporation Integrated laser imaging and spectral analysis system

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1485687A4 *

Also Published As

Publication number Publication date
CA2475233C (en) 2013-07-02
WO2003067214A2 (en) 2003-08-14
US20030147066A1 (en) 2003-08-07
US6654118B2 (en) 2003-11-25
CA2475233A1 (en) 2003-08-14
MXPA04008549A (en) 2005-09-08
AU2003212885A1 (en) 2003-09-02
AU2003212885B2 (en) 2007-09-20
AU2003212885C1 (en) 2008-04-24

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