WO2003074990A3 - Artificial receptors, building blocks, and methods - Google Patents
Artificial receptors, building blocks, and methods Download PDFInfo
- Publication number
- WO2003074990A3 WO2003074990A3 PCT/US2003/005328 US0305328W WO03074990A3 WO 2003074990 A3 WO2003074990 A3 WO 2003074990A3 US 0305328 W US0305328 W US 0305328W WO 03074990 A3 WO03074990 A3 WO 03074990A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- building blocks
- artificial receptors
- receptors
- methods
- arrays
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00387—Applications using probes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00572—Chemical means
- B01J2219/00576—Chemical means fluorophore
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/0061—The surface being organic
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/00626—Covalent
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00632—Introduction of reactive groups to the surface
- B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
- B01J2219/00662—Two-dimensional arrays within two-dimensional arrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2600/00—Assays involving molecular imprinted polymers/polymers created around a molecular template
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Abstract
Priority Applications (20)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003213204A AU2003213204B2 (en) | 2002-03-01 | 2003-02-19 | Artificial receptors, building blocks, and methods |
NZ535080A NZ535080A (en) | 2002-03-01 | 2003-02-19 | Artificial receptors, building blocks, and methods |
CA002477749A CA2477749A1 (en) | 2002-03-01 | 2003-02-19 | Artificial receptors, building blocks, and methods |
EP03709250A EP1483578B1 (en) | 2002-03-01 | 2003-02-19 | Artificial receptors, building blocks, and methods |
IL16368603A IL163686A0 (en) | 2002-03-01 | 2003-02-19 | Artificial receptors, building blocks, and methods |
AT03709250T ATE538379T1 (en) | 2002-03-01 | 2003-02-19 | ARTIFICIAL RECEPTORS, COMPONENTS AND PROCESSES |
MXPA04008467A MXPA04008467A (en) | 2002-03-01 | 2003-02-19 | Artificial receptors, building blocks, and methods. |
JP2003573401A JP4988147B2 (en) | 2002-03-01 | 2003-02-19 | Artificial receptors, building blocks, and methods |
US10/813,568 US20050037381A1 (en) | 2002-09-16 | 2004-03-29 | Artificial receptors, building blocks, and methods |
US10/812,850 US20050037428A1 (en) | 2002-09-16 | 2004-03-29 | Artificial receptors including reversibly immobilized building blocks, the building blocks, and methods |
IL163686A IL163686A (en) | 2002-03-01 | 2004-08-23 | Methods of making arrays of artificial receptors |
ZA200406710A ZA200406710B (en) | 2002-03-01 | 2004-08-24 | Artificial receptors, building blocks, and methods |
US10/934,865 US20050106630A1 (en) | 2002-09-16 | 2004-09-03 | Building blocks for artificial receptors |
US10/934,977 US7960311B2 (en) | 2002-09-16 | 2004-09-03 | Methods employing combinatorial artificial receptors |
US11/004,593 US20050170385A1 (en) | 2002-09-16 | 2004-12-02 | Artificial receptors including gradients |
US11/217,384 US20060057625A1 (en) | 2002-09-16 | 2005-09-01 | Scaffold-based artificial receptors and methods |
US11/709,696 US20070238091A1 (en) | 2002-09-16 | 2007-02-22 | Artificial receptors, building blocks, and methods |
US11/978,936 US20080058225A1 (en) | 2002-09-16 | 2007-10-30 | Artificial receptors, building blocks, and methods |
AU2009200852A AU2009200852A1 (en) | 2002-03-01 | 2009-03-04 | Artificial receptors, building blocks, and methods |
IL199259A IL199259A0 (en) | 2002-03-01 | 2009-06-09 | Artificial receptors, building blocks, and methods |
Applications Claiming Priority (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36098002P | 2002-03-01 | 2002-03-01 | |
US60/360,980 | 2002-03-01 | ||
US36260002P | 2002-03-08 | 2002-03-08 | |
US60/362,600 | 2002-03-08 | ||
US37565502P | 2002-04-26 | 2002-04-26 | |
US60/375,655 | 2002-04-26 | ||
US40060502P | 2002-08-02 | 2002-08-02 | |
US60/400,605 | 2002-08-02 | ||
US10/244,727 US7504364B2 (en) | 2002-03-01 | 2002-09-16 | Methods of making arrays and artificial receptors |
US10/244,727 | 2002-09-16 |
Related Child Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/813,568 Continuation-In-Part US20050037381A1 (en) | 2002-09-16 | 2004-03-29 | Artificial receptors, building blocks, and methods |
US10/812,850 Continuation-In-Part US20050037428A1 (en) | 2002-09-16 | 2004-03-29 | Artificial receptors including reversibly immobilized building blocks, the building blocks, and methods |
US10/934,865 Continuation-In-Part US20050106630A1 (en) | 2002-09-16 | 2004-09-03 | Building blocks for artificial receptors |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2003074990A2 WO2003074990A2 (en) | 2003-09-12 |
WO2003074990A9 WO2003074990A9 (en) | 2004-01-22 |
WO2003074990A3 true WO2003074990A3 (en) | 2004-07-29 |
Family
ID=29255676
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/005328 WO2003074990A2 (en) | 2002-03-01 | 2003-02-19 | Artificial receptors, building blocks, and methods |
Country Status (11)
Country | Link |
---|---|
US (5) | US7504364B2 (en) |
EP (1) | EP1483578B1 (en) |
JP (1) | JP4988147B2 (en) |
CN (1) | CN100533145C (en) |
AT (1) | ATE538379T1 (en) |
AU (2) | AU2003213204B2 (en) |
CA (1) | CA2477749A1 (en) |
IL (3) | IL163686A0 (en) |
MX (1) | MXPA04008467A (en) |
NZ (1) | NZ535080A (en) |
WO (1) | WO2003074990A2 (en) |
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US7504364B2 (en) | 2002-03-01 | 2009-03-17 | Receptors Llc | Methods of making arrays and artificial receptors |
US7469076B2 (en) | 2003-09-03 | 2008-12-23 | Receptors Llc | Sensors employing combinatorial artificial receptors |
US7736909B2 (en) * | 2003-01-09 | 2010-06-15 | Board Of Regents, The University Of Texas System | Methods and compositions comprising capture agents |
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EP1613737A4 (en) | 2003-03-28 | 2008-12-03 | Receptors Llc | Artificial receptors including reversibly immobilized building blocks and methods |
EP1664792A2 (en) * | 2003-09-03 | 2006-06-07 | Receptors LLC | Building blocks for artificial receptors |
CA2537306A1 (en) * | 2003-09-03 | 2005-03-17 | Receptors Llc | Methods employing combinatorial artificial receptors |
JP4711326B2 (en) * | 2003-12-22 | 2011-06-29 | キヤノン株式会社 | Preparation method of calibration sample and calibration curve |
WO2006028930A2 (en) | 2004-09-03 | 2006-03-16 | Receptors Llc | Combinatorial artificial receptors including tether building blocks on scaffolds |
EP1789792A2 (en) | 2004-09-11 | 2007-05-30 | Receptors LLC | Combinatorial artificial receptors including peptide building blocks |
US7879764B2 (en) * | 2004-12-28 | 2011-02-01 | Intel Corporation | Electrically active combinatorial chemical (EACC) chip for biochemical analyte detection |
US20090203980A1 (en) * | 2007-11-29 | 2009-08-13 | Carlson Robert E | Sensors employing combinatorial artificial receptors |
US20100137143A1 (en) * | 2008-10-22 | 2010-06-03 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
US20100301398A1 (en) | 2009-05-29 | 2010-12-02 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
CA2763685A1 (en) * | 2009-05-29 | 2010-12-02 | The Board Of Regents Of The University Of Texas System | Peptoid ligands for isolation and treatment of autoimmune t-cells |
AU2010256880B2 (en) * | 2009-06-02 | 2015-01-22 | Opko Health, Inc. | Identification of small molecules recognized by antibodies in subjects with neurodegenerative diseases |
US8759259B2 (en) * | 2009-10-16 | 2014-06-24 | The Board Of Regents Of The University Of Texas System | Compositions and methods for producing cyclic peptoid libraries |
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US8900352B2 (en) | 2011-07-06 | 2014-12-02 | Northwestern University | System and method for generating and/or screening potential metal-organic frameworks |
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CN105229467A (en) * | 2013-03-15 | 2016-01-06 | 普林斯顿大学理事会 | Quick and sensitive analysis measurement determination method |
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US20030203405A1 (en) | 2003-10-30 |
NZ535080A (en) | 2007-05-31 |
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