WO2003076883A8 - Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy - Google Patents
Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopyInfo
- Publication number
- WO2003076883A8 WO2003076883A8 PCT/US2003/007065 US0307065W WO03076883A8 WO 2003076883 A8 WO2003076883 A8 WO 2003076883A8 US 0307065 W US0307065 W US 0307065W WO 03076883 A8 WO03076883 A8 WO 03076883A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- glucose
- infrared spectroscopy
- compact apparatus
- noninvasive measurement
- analyzer
- Prior art date
Links
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title abstract 2
- 239000008103 glucose Substances 0.000 title abstract 2
- 238000005259 measurement Methods 0.000 title abstract 2
- 238000004497 NIR spectroscopy Methods 0.000 title 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 230000003595 spectral effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1495—Calibrating or testing of in-vivo probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/683—Means for maintaining contact with the body
- A61B5/6832—Means for maintaining contact with the body using adhesives
- A61B5/6833—Adhesive patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7225—Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
- G01N21/359—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0223—Operational features of calibration, e.g. protocols for calibrating sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0223—Operational features of calibration, e.g. protocols for calibrating sensors
- A61B2560/0228—Operational features of calibration, e.g. protocols for calibrating sensors using calibration standards
- A61B2560/0233—Optical standards
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0242—Operational features adapted to measure environmental factors, e.g. temperature, pollution
- A61B2560/0247—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value
- A61B2560/0252—Operational features adapted to measure environmental factors, e.g. temperature, pollution for compensation or correction of the measured physiological value using ambient temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/04—Constructional details of apparatus
- A61B2560/0406—Constructional details of apparatus specially shaped apparatus housings
- A61B2560/0412—Low-profile patch shaped housings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/04—Constructional details of apparatus
- A61B2560/0443—Modular apparatus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/04—Constructional details of apparatus
- A61B2560/0456—Apparatus provided with a docking unit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0233—Special features of optical sensors or probes classified in A61B5/00
- A61B2562/0242—Special features of optical sensors or probes classified in A61B5/00 for varying or adjusting the optical path length in the tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/14—Coupling media or elements to improve sensor contact with skin or tissue
- A61B2562/146—Coupling media or elements to improve sensor contact with skin or tissue for optical coupling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/22—Arrangements of medical sensors with cables or leads; Connectors or couplings specifically adapted for medical sensors
- A61B2562/225—Connectors or couplings
- A61B2562/227—Sensors with electrical connectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/22—Arrangements of medical sensors with cables or leads; Connectors or couplings specifically adapted for medical sensors
- A61B2562/225—Connectors or couplings
- A61B2562/228—Sensors with optical connectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7253—Details of waveform analysis characterised by using transforms
- A61B5/726—Details of waveform analysis characterised by using transforms using Wavelet transforms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
- G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
Abstract
Priority Applications (30)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003575060A JP4189322B2 (en) | 2002-03-08 | 2003-03-07 | Compact instrument for non-invasive measurement of glucose by near infrared spectroscopy |
EP03713991A EP1499231A4 (en) | 2002-03-08 | 2003-03-07 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
CA002476421A CA2476421A1 (en) | 2002-03-08 | 2003-03-07 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
MXPA04008713A MXPA04008713A (en) | 2002-03-08 | 2003-03-07 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy. |
IL16353803A IL163538A0 (en) | 2002-03-08 | 2003-03-07 | Compact apparatus for noninvasive measurement of glucose through nearinfrared spectroscopy |
US10/472,856 US7133710B2 (en) | 2002-03-08 | 2003-03-07 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
AU2003218012A AU2003218012A1 (en) | 2002-03-08 | 2003-03-07 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US10/820,322 US7299080B2 (en) | 1999-10-08 | 2004-04-07 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US10/841,200 US20050054908A1 (en) | 2003-03-07 | 2004-05-06 | Photostimulation method and apparatus in combination with glucose determination |
US10/971,447 US20050107676A1 (en) | 2003-03-07 | 2004-10-21 | Method and apparatus for noninvasive glucose concentration estimation through near-infrared spectroscopy |
US10/976,530 US7620674B2 (en) | 2003-03-07 | 2004-10-29 | Method and apparatus for enhanced estimation of an analyte property through multiple region transformation |
US10/978,116 US7317938B2 (en) | 1999-10-08 | 2004-10-29 | Method of adapting in-vitro models to aid in noninvasive glucose determination |
US11/008,001 US7606608B2 (en) | 2000-05-02 | 2004-12-08 | Optical sampling interface system for in-vivo measurement of tissue |
US11/012,428 US7440786B2 (en) | 2002-03-08 | 2004-12-14 | Method and apparatus for presentation of noninvasive glucose concentration information |
US11/012,441 US20050159656A1 (en) | 2003-03-07 | 2004-12-14 | Method and apparatus for presentation of noninvasive glucose concentration information |
US11/031,103 US20050187439A1 (en) | 2003-03-07 | 2005-01-06 | Sampling interface system for in-vivo estimation of tissue analyte concentration |
US11/095,331 US7640140B2 (en) | 2003-03-07 | 2005-03-30 | Method of processing noninvasive spectra |
US11/324,876 US7787924B2 (en) | 2002-03-08 | 2006-01-03 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US11/326,958 US20060195023A1 (en) | 2002-03-08 | 2006-01-05 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US11/328,543 US20060211927A1 (en) | 2002-03-08 | 2006-01-09 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US11/328,902 US20060173255A1 (en) | 2002-03-08 | 2006-01-09 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US11/335,773 US20060183983A1 (en) | 2002-03-08 | 2006-01-18 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US11/335,067 US20060116562A1 (en) | 2002-03-08 | 2006-01-18 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US11/359,700 US20060211931A1 (en) | 2000-05-02 | 2006-02-21 | Noninvasive analyzer sample probe interface method and apparatus |
US11/361,143 US7697966B2 (en) | 2002-03-08 | 2006-02-23 | Noninvasive targeting system method and apparatus |
US11/538,737 US20070149868A1 (en) | 2002-03-08 | 2006-10-04 | Method and Apparatus for Photostimulation Enhanced Analyte Property Estimation |
US12/109,224 US8504128B2 (en) | 2002-03-08 | 2008-04-24 | Method and apparatus for coupling a channeled sample probe to tissue |
US12/110,183 US20090318786A1 (en) | 2002-03-08 | 2008-04-25 | Channeled tissue sample probe method and apparatus |
US12/393,867 US8718738B2 (en) | 2002-03-08 | 2009-02-26 | Method and apparatus for coupling a sample probe with a sample site |
US14/268,709 US20140316228A1 (en) | 2002-03-08 | 2014-05-02 | Method and apparatus for coupling a sample probe with a sample site |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36288502P | 2002-03-08 | 2002-03-08 | |
US36289902P | 2002-03-08 | 2002-03-08 | |
US60/362,885 | 2002-03-08 | ||
US60/362,899 | 2002-03-08 | ||
US44884003P | 2003-02-19 | 2003-02-19 | |
US60/448,840 | 2003-02-19 |
Related Child Applications (16)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/415,389 Continuation-In-Part US6411373B1 (en) | 1999-10-08 | 1999-10-08 | Fiber optic illumination and detection patterns, shapes, and locations for use in spectroscopic analysis |
US10/472,856 A-371-Of-International US7133710B2 (en) | 1999-10-08 | 2003-03-07 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US10/820,322 Continuation-In-Part US7299080B2 (en) | 1999-04-09 | 2004-04-07 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US11/008,001 Continuation-In-Part US7606608B2 (en) | 2000-05-02 | 2004-12-08 | Optical sampling interface system for in-vivo measurement of tissue |
US11/012,428 Continuation-In-Part US7440786B2 (en) | 2002-03-08 | 2004-12-14 | Method and apparatus for presentation of noninvasive glucose concentration information |
US11/324,876 Continuation US7787924B2 (en) | 2002-03-08 | 2006-01-03 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US11/324,876 Division US7787924B2 (en) | 2002-03-08 | 2006-01-03 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US11/326,958 Division US20060195023A1 (en) | 2002-03-08 | 2006-01-05 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US11/328,543 Division US20060211927A1 (en) | 2002-03-08 | 2006-01-09 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US11/328,902 Division US20060173255A1 (en) | 2002-03-08 | 2006-01-09 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US11/335,067 Continuation US20060116562A1 (en) | 2002-03-08 | 2006-01-18 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US11/335,773 Continuation US20060183983A1 (en) | 2002-03-08 | 2006-01-18 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
US11/359,700 Continuation-In-Part US20060211931A1 (en) | 2000-05-02 | 2006-02-21 | Noninvasive analyzer sample probe interface method and apparatus |
US11/361,143 Continuation-In-Part US7697966B2 (en) | 2002-03-08 | 2006-02-23 | Noninvasive targeting system method and apparatus |
US11/538,737 Continuation-In-Part US20070149868A1 (en) | 2002-03-08 | 2006-10-04 | Method and Apparatus for Photostimulation Enhanced Analyte Property Estimation |
US12/393,867 Continuation US8718738B2 (en) | 2002-03-08 | 2009-02-26 | Method and apparatus for coupling a sample probe with a sample site |
Publications (4)
Publication Number | Publication Date |
---|---|
WO2003076883A2 WO2003076883A2 (en) | 2003-09-18 |
WO2003076883A3 WO2003076883A3 (en) | 2004-08-12 |
WO2003076883B1 WO2003076883B1 (en) | 2004-10-14 |
WO2003076883A8 true WO2003076883A8 (en) | 2005-01-13 |
Family
ID=29587644
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/007065 WO2003076883A2 (en) | 1999-10-08 | 2003-03-07 | Compact apparatus for noninvasive measurement of glucose through near-infrared spectroscopy |
Country Status (10)
Country | Link |
---|---|
US (7) | US7133710B2 (en) |
EP (1) | EP1499231A4 (en) |
JP (1) | JP4189322B2 (en) |
CN (1) | CN100421615C (en) |
AU (1) | AU2003218012A1 (en) |
CA (1) | CA2476421A1 (en) |
IL (1) | IL163538A0 (en) |
MX (1) | MXPA04008713A (en) |
TW (1) | TWI284200B (en) |
WO (1) | WO2003076883A2 (en) |
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- 2006-01-18 US US11/335,067 patent/US20060116562A1/en not_active Abandoned
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CN1638690A (en) | 2005-07-13 |
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WO2003076883A2 (en) | 2003-09-18 |
TWI284200B (en) | 2007-07-21 |
US20060195023A1 (en) | 2006-08-31 |
TW200404156A (en) | 2004-03-16 |
CN100421615C (en) | 2008-10-01 |
EP1499231A4 (en) | 2007-09-26 |
US20060211927A1 (en) | 2006-09-21 |
US20060173255A1 (en) | 2006-08-03 |
US7133710B2 (en) | 2006-11-07 |
WO2003076883B1 (en) | 2004-10-14 |
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