WO2003078583A3 - Optimization of crossover points for directed evolution - Google Patents
Optimization of crossover points for directed evolution Download PDFInfo
- Publication number
- WO2003078583A3 WO2003078583A3 PCT/US2003/007610 US0307610W WO03078583A3 WO 2003078583 A3 WO2003078583 A3 WO 2003078583A3 US 0307610 W US0307610 W US 0307610W WO 03078583 A3 WO03078583 A3 WO 03078583A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- optimization
- methods
- directed evolution
- crossover points
- sequences
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
- G16B15/20—Protein or domain folding
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
- G16B30/10—Sequence alignment; Homology search
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B35/00—ICT specially adapted for in silico combinatorial libraries of nucleic acids, proteins or peptides
- G16B35/20—Screening of libraries
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
- G16C20/60—In silico combinatorial chemistry
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B15/00—ICT specially adapted for analysing two-dimensional or three-dimensional molecular structures, e.g. structural or functional relations or structure alignment
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003576577A JP4851687B2 (en) | 2002-03-09 | 2003-03-10 | Crossover optimization for directed evolution |
EP03711540A EP1488335A4 (en) | 2002-03-09 | 2003-03-10 | Optimization of crossover points for directed evolution |
AU2003213846A AU2003213846A1 (en) | 2002-03-09 | 2003-03-10 | Optimization of crossover points for directed evolution |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36350502P | 2002-03-09 | 2002-03-09 | |
US60/363,505 | 2002-03-09 | ||
US37359102P | 2002-04-18 | 2002-04-18 | |
US60/373,591 | 2002-04-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003078583A2 WO2003078583A2 (en) | 2003-09-25 |
WO2003078583A3 true WO2003078583A3 (en) | 2004-03-18 |
Family
ID=28045308
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/007610 WO2003078583A2 (en) | 2002-03-09 | 2003-03-10 | Optimization of crossover points for directed evolution |
Country Status (5)
Country | Link |
---|---|
US (3) | US7620500B2 (en) |
EP (1) | EP1488335A4 (en) |
JP (3) | JP4851687B2 (en) |
AU (1) | AU2003213846A1 (en) |
WO (1) | WO2003078583A2 (en) |
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WO2001075767A2 (en) * | 2000-03-30 | 2001-10-11 | Maxygen, Inc. | In silico cross-over site selection |
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-
2003
- 2003-03-10 JP JP2003576577A patent/JP4851687B2/en not_active Expired - Fee Related
- 2003-03-10 WO PCT/US2003/007610 patent/WO2003078583A2/en active Application Filing
- 2003-03-10 AU AU2003213846A patent/AU2003213846A1/en not_active Abandoned
- 2003-03-10 EP EP03711540A patent/EP1488335A4/en not_active Withdrawn
- 2003-03-10 US US10/386,903 patent/US7620500B2/en active Active
-
2007
- 2007-06-12 US US11/818,237 patent/US8224580B2/en not_active Expired - Fee Related
-
2009
- 2009-08-17 JP JP2009188786A patent/JP2010015581A/en not_active Withdrawn
- 2009-09-10 US US12/557,434 patent/US8108150B2/en not_active Expired - Fee Related
-
2011
- 2011-05-19 JP JP2011112828A patent/JP2011217751A/en not_active Withdrawn
Patent Citations (1)
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WO2001075767A2 (en) * | 2000-03-30 | 2001-10-11 | Maxygen, Inc. | In silico cross-over site selection |
Non-Patent Citations (1)
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STEMMER W.P.C.: "Rapid evolution of a protein in vitro by DNA shuffling", NATURE, vol. 370, 4 August 1994 (1994-08-04), pages 389 - 391, XP002912216 * |
Also Published As
Publication number | Publication date |
---|---|
US8224580B2 (en) | 2012-07-17 |
JP4851687B2 (en) | 2012-01-11 |
JP2010015581A (en) | 2010-01-21 |
EP1488335A4 (en) | 2006-11-15 |
JP2011217751A (en) | 2011-11-04 |
AU2003213846A8 (en) | 2003-09-29 |
AU2003213846A1 (en) | 2003-09-29 |
US20030198988A1 (en) | 2003-10-23 |
US20080020397A1 (en) | 2008-01-24 |
WO2003078583A2 (en) | 2003-09-25 |
JP2005520244A (en) | 2005-07-07 |
US8108150B2 (en) | 2012-01-31 |
US7620500B2 (en) | 2009-11-17 |
EP1488335A2 (en) | 2004-12-22 |
US20100070192A1 (en) | 2010-03-18 |
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