WO2004000197A3 - Quick dissolve compositions and tablets based thereon - Google Patents
Quick dissolve compositions and tablets based thereon Download PDFInfo
- Publication number
- WO2004000197A3 WO2004000197A3 PCT/US2003/019527 US0319527W WO2004000197A3 WO 2004000197 A3 WO2004000197 A3 WO 2004000197A3 US 0319527 W US0319527 W US 0319527W WO 2004000197 A3 WO2004000197 A3 WO 2004000197A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- friability
- composition
- inorganic salt
- cellulose derivative
- compositions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ537744A NZ537744A (en) | 2002-06-21 | 2003-06-23 | Oral dosage forms / tablets comprising liquiflash particles manufactured without floss matrices |
AU2003243696A AU2003243696B2 (en) | 2002-06-21 | 2003-06-23 | Quick dissolve compositions and tablets based thereon |
JP2004516037A JP2005535622A (en) | 2002-06-21 | 2003-06-23 | Quick-dissolving composition and tablets based thereon |
CA002490365A CA2490365A1 (en) | 2002-06-21 | 2003-06-23 | Quick dissolve compositions and tablets based thereon |
MXPA04012877A MXPA04012877A (en) | 2002-06-21 | 2003-06-23 | Quick dissolve compositions and tablets based thereon. |
EP03761197A EP1553909A4 (en) | 2002-06-21 | 2003-06-23 | Quick dissolve compositions and tablets based thereon |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/176,135 US7815937B2 (en) | 1998-10-27 | 2002-06-21 | Quick dissolve compositions and tablets based thereon |
US10/176,135 | 2002-06-21 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004000197A2 WO2004000197A2 (en) | 2003-12-31 |
WO2004000197A3 true WO2004000197A3 (en) | 2005-03-24 |
Family
ID=29999057
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/019527 WO2004000197A2 (en) | 2002-06-21 | 2003-06-23 | Quick dissolve compositions and tablets based thereon |
Country Status (8)
Country | Link |
---|---|
US (1) | US7815937B2 (en) |
EP (1) | EP1553909A4 (en) |
JP (2) | JP2005535622A (en) |
AU (1) | AU2003243696B2 (en) |
CA (1) | CA2490365A1 (en) |
MX (1) | MXPA04012877A (en) |
NZ (1) | NZ537744A (en) |
WO (1) | WO2004000197A2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11957694B2 (en) | 2015-06-18 | 2024-04-16 | Estetra Srl | Orodispersible dosage unit containing an estetrol component |
US11964055B2 (en) | 2015-06-18 | 2024-04-23 | Estetra Srl | Orodispersible dosage unit containing an estetrol component |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000024380A1 (en) * | 1998-10-27 | 2000-05-04 | Fuisz Technologies Ltd. | Microparticles containing peg and/or peg glyceryl esters |
US7815937B2 (en) | 1998-10-27 | 2010-10-19 | Biovail Laboratories International Srl | Quick dissolve compositions and tablets based thereon |
US8128957B1 (en) | 2002-02-21 | 2012-03-06 | Valeant International (Barbados) Srl | Modified release compositions of at least one form of tramadol |
US20050182056A9 (en) * | 2002-02-21 | 2005-08-18 | Seth Pawan | Modified release formulations of at least one form of tramadol |
CA2392486A1 (en) * | 2002-07-05 | 2002-12-08 | Duchesnay Inc. | Pharmaceutical dosage form bearing pregnancy-friendly indicia |
US20080213363A1 (en) * | 2003-01-23 | 2008-09-04 | Singh Nikhilesh N | Methods and compositions for delivering 5-HT3 antagonists across the oral mucosa |
US20040265375A1 (en) * | 2003-04-16 | 2004-12-30 | Platteeuw Johannes J. | Orally disintegrating tablets |
US8349361B2 (en) * | 2003-10-15 | 2013-01-08 | Fuji Chemical Industry Co., Ltd. | Composition for rapid disintegrating tablet in oral cavity |
JP3841804B2 (en) * | 2003-10-15 | 2006-11-08 | 富士化学工業株式会社 | Composition for intraorally rapidly disintegrating tablets |
US20050196441A1 (en) * | 2003-11-05 | 2005-09-08 | Dvorsky James E. | Quick dissolving agrochemical and animal health products |
US7879354B2 (en) * | 2004-01-13 | 2011-02-01 | Mcneil-Ppc, Inc. | Rapidly disintegrating gelatinous coated tablets |
KR20130006523A (en) * | 2004-02-17 | 2013-01-16 | 트랜스셉트 파마슈티칼스, 인코포레이티드 | Compositions for delivering hypnotic agents across the oral mucosa and methods of use thereof |
US8545881B2 (en) * | 2004-04-19 | 2013-10-01 | Eurand Pharmaceuticals, Ltd. | Orally disintegrating tablets and methods of manufacture |
US20050244493A1 (en) * | 2004-04-30 | 2005-11-03 | Withiam Michael C | Rapidly disintegrating tablets comprising calcium carbonate |
US20050244343A1 (en) * | 2004-04-30 | 2005-11-03 | Withiam Michael C | Oral care products comprising silica |
US20070196477A1 (en) * | 2004-04-30 | 2007-08-23 | Withiam Michael C | Rapidly dissolving tablets comprising low surface area calcium phosphates |
US20070196475A1 (en) * | 2004-04-30 | 2007-08-23 | Withiam Michael C | Rapidly disintegrating low friability tablets comprising silica materials |
US20050244347A1 (en) * | 2004-04-30 | 2005-11-03 | Mehra Dev K | Oral care products comprising calcium phosphates |
US20070196476A1 (en) * | 2004-04-30 | 2007-08-23 | Withiam Michael C | Rapidly dissolving tablets comprising low surface area titanium dioxide |
US20050244492A1 (en) * | 2004-04-30 | 2005-11-03 | Mehra Dev K | Rapidly disintegrating tablets comprising titanium dioxide |
US20070196474A1 (en) * | 2004-04-30 | 2007-08-23 | Withiam Michael C | Rapidly disintegrating low friability tablets comprising calcium carbonate |
PL1750862T3 (en) | 2004-06-04 | 2011-06-30 | Teva Pharma | Pharmaceutical composition containing irbesartan |
WO2005123040A1 (en) * | 2004-06-22 | 2005-12-29 | Shionogi & Co., Ltd. | Tablet rapidly disintegrating in mouth |
US20070287740A1 (en) * | 2005-05-25 | 2007-12-13 | Transcept Pharmaceuticals, Inc. | Compositions and methods of treating middle-of-the night insomnia |
US20070225322A1 (en) * | 2005-05-25 | 2007-09-27 | Transoral Pharmaceuticals, Inc. | Compositions and methods for treating middle-of-the night insomnia |
KR20080031208A (en) * | 2005-05-25 | 2008-04-08 | 트랜스셉트 파마슈티칼스, 인코포레이티드 | Solid compositions and methods for treating middle-of-the night insomnia |
WO2006133349A2 (en) * | 2005-06-08 | 2006-12-14 | Alpharma, Inc. | Orally disintegrable sleep aid formulations |
EP1897558B1 (en) * | 2005-06-09 | 2013-09-04 | Norgine BV | Solid preparation of 2-hexadecyloxy-6-methyl-4h-3,1-benzoxazin-4-one |
US7811604B1 (en) | 2005-11-14 | 2010-10-12 | Barr Laboratories, Inc. | Non-effervescent, orally disintegrating solid pharmaceutical dosage forms comprising clozapine and methods of making and using the same |
WO2007075408A2 (en) * | 2005-12-16 | 2007-07-05 | Effrx, Inc. | Effervescent compositions for triptans |
CN101431895A (en) * | 2006-05-01 | 2009-05-13 | 卡普里康制药公司 | Novel triptan formulations and methods for making them |
FR2910319B1 (en) | 2006-12-20 | 2011-06-03 | Substipharm Dev | DISPERSIBLE PHARMACEUTICAL FORMULATIONS CONTAINING FLUOXETINE |
US20100055179A1 (en) * | 2006-12-21 | 2010-03-04 | Mallinckrodt Inc. | Composition of and Method for Preparing Orally Disintegrating Tablets Containing a High Dose of Pharmaceutically Active Ingredients |
US8313770B2 (en) * | 2007-05-30 | 2012-11-20 | Neos Therapeutics, Lp | Modifying drug release in suspensions of ionic resin systems |
EP2164460B1 (en) * | 2007-06-06 | 2017-08-09 | Basf Se | Pharmaceutical formulation for the production of rapidly disintegrating tablets |
RU2482839C2 (en) * | 2007-10-31 | 2013-05-27 | МакНЕЙЛС-ППС, ИНК. | Drug form desintegrating in oral cavity |
PE20091084A1 (en) * | 2007-12-07 | 2009-07-23 | Schering Plough Healthcare | PHARMACEUTICAL FORMULATIONS OF PHENYLPHRINE AND COMPOSITIONS FOR TRANSMUCOSAL ABSORPTION |
EP2331076B1 (en) * | 2008-09-04 | 2015-03-04 | Farnam Companies, Inc. | Chewable sustained release formulations |
EP2410995A1 (en) | 2009-03-26 | 2012-02-01 | Royal College of Surgeons in Ireland | Orodispersible tablets |
ES2604307T3 (en) | 2009-05-20 | 2017-03-06 | Sumitomo Dainippon Pharma Co., Ltd. | Dry-coated oral disintegration tablet |
US8858210B2 (en) | 2009-09-24 | 2014-10-14 | Mcneil-Ppc, Inc. | Manufacture of variable density dosage forms utilizing radiofrequency energy |
US9610224B2 (en) | 2009-09-24 | 2017-04-04 | Johnson & Johnson Consumer Inc. | Manufacture of tablet in a die utilizing powder blend containing water-containing material |
US8313768B2 (en) | 2009-09-24 | 2012-11-20 | Mcneil-Ppc, Inc. | Manufacture of tablet having immediate release region and sustained release region |
KR101907218B1 (en) | 2009-12-11 | 2018-10-11 | 다이닛본 스미토모 세이야꾸 가부시끼가이샤 | Press-coated orally disintegrating tablets |
US20130177646A1 (en) * | 2012-01-05 | 2013-07-11 | Mcneil Ab | Solid Nicotine-Comprising Dosage Form with Reduced Organoleptic Disturbance |
JP5956475B2 (en) | 2012-02-03 | 2016-07-27 | 旭化成株式会社 | Orally disintegrating tablets containing bitter mask granules |
US9445971B2 (en) | 2012-05-01 | 2016-09-20 | Johnson & Johnson Consumer Inc. | Method of manufacturing solid dosage form |
US9511028B2 (en) | 2012-05-01 | 2016-12-06 | Johnson & Johnson Consumer Inc. | Orally disintegrating tablet |
JP6045238B2 (en) * | 2012-07-27 | 2016-12-14 | 旭化成株式会社 | Tablet containing thickening polysaccharide |
WO2014022541A1 (en) * | 2012-08-01 | 2014-02-06 | Acura Pharmaceuticals, Inc. | Stabilization of one-pot methamphetamine synthesis systems |
KR20160107254A (en) | 2014-01-10 | 2016-09-13 | 존슨 앤드 존슨 컨수머 인코포레이티드 | Process for making tablet using radiofrequency and lossy coated particles |
CA2845443A1 (en) * | 2014-03-04 | 2015-09-04 | Pharmascience Inc. | Orally disintegrating tablet of nabilone and method of manufacturing |
US20160008310A1 (en) | 2014-07-11 | 2016-01-14 | Azanta A/S | Misoprostol dispersible tablet |
CU24504B1 (en) | 2015-06-18 | 2021-04-07 | Estetra Sprl | ORODISPERSABLE DOSING UNIT CONTAINING A STETROL COMPONENT AND A PROCESS INCLUDING A GRANULATION STEP TO PREPARE THE SAME |
KR20220144885A (en) | 2016-08-05 | 2022-10-27 | 에스테트라, 소시에떼 아 레스폰서빌리떼 리미떼 | Method for the management of dysmenorrhea and menstrual pain |
US10493026B2 (en) | 2017-03-20 | 2019-12-03 | Johnson & Johnson Consumer Inc. | Process for making tablet using radiofrequency and lossy coated particles |
TWI801561B (en) | 2018-04-19 | 2023-05-11 | 比利時商依思特拉私人有限責任公司 | Compounds and their uses for alleviating menopause-associated symptoms |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5871781A (en) * | 1993-09-10 | 1999-02-16 | Fuisz Technologies Ltd. | Apparatus for making rapidly-dissolving dosage units |
Family Cites Families (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5438167B2 (en) | 1974-04-27 | 1979-11-19 | ||
US4517179A (en) * | 1983-04-29 | 1985-05-14 | Pennwalt Corporation | Rapid dissolving, uniform drug compositions and their preparation |
PH20837A (en) * | 1983-04-29 | 1987-05-08 | Pennwalt Corp | Rapid dissolving uniform drug compositon |
FR2571046B1 (en) * | 1984-10-03 | 1987-10-16 | Roquette Freres | PROCESS FOR THE PREPARATION OF DIRECTLY COMPRESSIBLE GRANULAR MANNITOL |
US5536526A (en) * | 1988-01-11 | 1996-07-16 | Cultor Ltd. | Xylitol-based binding and diluting agent and a process for the production thereof |
US5073374A (en) | 1988-11-30 | 1991-12-17 | Schering Corporation | Fast dissolving buccal tablet |
US5204115A (en) * | 1990-12-12 | 1993-04-20 | Suomen Xyrofin Oy | Directly compressible xylitol and method |
US5464632C1 (en) * | 1991-07-22 | 2001-02-20 | Prographarm Lab | Rapidly disintegratable multiparticular tablet |
US6468959B1 (en) | 1991-12-05 | 2002-10-22 | Alfatec-Pharm Gmbh | Peroral dosage form for peptide containing medicaments, in particular insulin |
CA2128820A1 (en) | 1993-07-27 | 1995-01-28 | Walter G. Gowan, Jr. | Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof |
US5472714A (en) * | 1993-09-08 | 1995-12-05 | Ciba-Geigy Corporation | Double-layered oxcarbazepine tablets |
US5595761A (en) | 1994-01-27 | 1997-01-21 | The Board Of Regents Of The University Of Oklahoma | Particulate support matrix for making a rapidly dissolving tablet |
JP3125565B2 (en) * | 1994-03-25 | 2001-01-22 | 松下電器産業株式会社 | Image coding method |
US6083430A (en) | 1994-10-28 | 2000-07-04 | Fuisz Technologies Ltd. | Method of preparing a dosage unit by direct tableting and product therefrom |
US5683720A (en) * | 1994-10-28 | 1997-11-04 | Fuisz Technologies Ltd. | Liquiflash particles and method of making same |
US5686720A (en) | 1995-03-02 | 1997-11-11 | Hewlett Packard Company | Method and device for achieving high contrast surface illumination |
US5762961A (en) | 1996-02-09 | 1998-06-09 | Quadrant Holdings Cambridge Ltd. | Rapidly soluble oral solid dosage forms, methods of making same, and compositions thereof |
US6024981A (en) * | 1997-04-16 | 2000-02-15 | Cima Labs Inc. | Rapidly dissolving robust dosage form |
FR2766089B1 (en) | 1997-07-21 | 2000-06-02 | Prographarm Lab | IMPROVED MULTIPARTICULAR TABLET WITH RAPID DELIVERY |
DK1001748T3 (en) | 1997-07-25 | 2006-08-21 | Alpex Pharma Sa | Process for the preparation of a granule suitable for the preparation of tablets which can be dissolved in the mouth which can be rapidly decomposed |
US5851555A (en) | 1997-08-15 | 1998-12-22 | Fuisz Technologies Ltd. | Controlled release dosage forms containing water soluble drugs |
US5980941A (en) | 1997-08-20 | 1999-11-09 | Fuisz Technologies Ltd. | Self-binding shearform compositions |
US5869098A (en) * | 1997-08-20 | 1999-02-09 | Fuisz Technologies Ltd. | Fast-dissolving comestible units formed under high-speed/high-pressure conditions |
PT1019039E (en) | 1997-10-03 | 2002-04-29 | Warner Lambert Co | NITROGLYCERIN COMPRESSED COMPRESSED AND METHOD FOR THEIR MANUFACTURE |
JP2002528042A (en) | 1997-10-07 | 2002-08-27 | フイズ テクノロジーズ リミテッド | Dosage forms with improved release characteristics |
US5965167A (en) | 1997-10-07 | 1999-10-12 | Sanghvi; Pradeepkumar P. | Dosage units |
HUP0100469A2 (en) * | 1997-12-19 | 2001-08-28 | Smithkline Beecham Corporation | Process for manufacturing bite-dispersion tablets |
CA2322315C (en) | 1998-03-06 | 2008-09-16 | Eurand International S.P.A. | Fast disintegrating tablets |
FR2781152B1 (en) | 1998-07-20 | 2001-07-06 | Permatec Tech Ag | USE OF ACRYLIC-TYPE POLYMER AS A DISAGGREGING AGENT |
US6086920A (en) | 1998-08-12 | 2000-07-11 | Fuisz Technologies Ltd. | Disintegratable microspheres |
US6117452A (en) | 1998-08-12 | 2000-09-12 | Fuisz Technologies Ltd. | Fatty ester combinations |
US20040013613A1 (en) | 2001-05-18 | 2004-01-22 | Jain Rajeev A | Rapidly disintegrating solid oral dosage form |
CA2346001C (en) * | 1998-10-01 | 2003-12-30 | Elan Pharma International, Limited | Controlled release nanoparticulate compositions |
US7815937B2 (en) | 1998-10-27 | 2010-10-19 | Biovail Laboratories International Srl | Quick dissolve compositions and tablets based thereon |
WO2000024380A1 (en) | 1998-10-27 | 2000-05-04 | Fuisz Technologies Ltd. | Microparticles containing peg and/or peg glyceryl esters |
US6165512A (en) | 1998-10-30 | 2000-12-26 | Fuisz Technologies Ltd. | Dosage forms containing taste masked active agents |
SE9804314D0 (en) * | 1998-12-14 | 1998-12-14 | Astra Ab | New pharmaceutical formulation |
FR2790387B1 (en) | 1999-03-01 | 2001-05-18 | Prographarm Laboratoires | ORODISPERSIBLE TABLET HAVING LOW FRIABILITY AND PROCESS FOR THE PREPARATION THEREOF |
US20020071864A1 (en) | 1999-03-25 | 2002-06-13 | Yuhan Corporation | Rapidly disintegrable tablet for oral administration |
DE19931708A1 (en) | 1999-07-08 | 2001-01-18 | Bayer Ag | Process for the preparation of rapidly disintegrating solid pharmaceutical preparations |
GB0001315D0 (en) * | 2000-01-20 | 2000-03-08 | Novartis Ag | Organic compounds |
EP1120109A3 (en) | 2000-01-24 | 2002-07-10 | Pfizer Products Inc. | Rapidly disintegrating and fast dissolving solid dosage form |
WO2003030868A1 (en) | 2001-10-09 | 2003-04-17 | Bristol-Myers Squibb Company | Flashmelt oral dosage formulation |
US6316029B1 (en) | 2000-05-18 | 2001-11-13 | Flak Pharma International, Ltd. | Rapidly disintegrating solid oral dosage form |
JP4698000B2 (en) * | 2000-06-27 | 2011-06-08 | 旭化成ケミカルズ株式会社 | Easily water-soluble drug-containing tablets |
JP2002154988A (en) * | 2000-11-21 | 2002-05-28 | Taiyo Yakuhin Kogyo Kk | Disintegrable tablet in oral cavity and method for producing the same |
US6733781B2 (en) | 2000-12-06 | 2004-05-11 | Wyeth | Fast dissolving tablet |
US7799342B2 (en) | 2000-12-06 | 2010-09-21 | Wyeth Llc | Fast dissolving tablet |
US20030022912A1 (en) | 2001-02-08 | 2003-01-30 | Martino Alice C. | Rapid-onset medicament for treatment of sexual dysfunction |
CA2437762C (en) | 2001-02-23 | 2010-08-10 | Cima Labs Inc. | Emulsions as solid dosage forms for oral administration |
US6692771B2 (en) | 2001-02-23 | 2004-02-17 | Cima Labs Inc. | Emulsions as solid dosage forms for oral administration |
HUP0400098A2 (en) | 2001-02-27 | 2004-04-28 | Ranbaxy Laboratories Limited | Fast dissolving tablets of cyclooxygenase-2 enzyme inhibitors and process for their preparation |
US6872405B2 (en) | 2001-05-10 | 2005-03-29 | Yamanouchi Pharmaceutical Co., Ltd. | Quick-disintegrating tablet in buccal cavity and manufacturing method thereof |
US7255876B2 (en) | 2001-07-27 | 2007-08-14 | Astellas Pharma, Inc. | Composition comprises sustained-release fine particles and manufacturing method thereof |
EA200400455A1 (en) | 2001-09-25 | 2004-10-28 | Ранбакси Лабораторис Лимитед | METHOD FOR PREPARING A QUICKLY SOLUBLE DOSAGE FORM |
HUP0401776A2 (en) | 2001-10-10 | 2004-12-28 | Pharmacia Corporation | Intraorally disintegrating valdecoxid compositions prepared by spray drying process |
US7118765B2 (en) | 2001-12-17 | 2006-10-10 | Spi Pharma, Inc. | Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms |
FR2834889B1 (en) | 2002-01-18 | 2004-04-02 | Roquette Freres | SOLID ORODISPERSIBLE PHARMACEUTICAL FORM |
US20030161875A1 (en) | 2002-02-27 | 2003-08-28 | Deepak Murpani | Fast dissolving tablets of cyclooxygenase-2 enzyme inhibitors |
US20040137060A1 (en) | 2002-05-13 | 2004-07-15 | Siobhan Fogarty | Enalapril microspheres, dosage forms and chronotherapeutic methods based thereon |
ES2199061B1 (en) | 2002-06-10 | 2005-02-16 | Laboratorios Vita, S.A. | TROUBLE-BASED TABLETS AND PROCEDURE FOR OBTAINING. |
-
2002
- 2002-06-21 US US10/176,135 patent/US7815937B2/en not_active Expired - Fee Related
-
2003
- 2003-06-23 CA CA002490365A patent/CA2490365A1/en not_active Abandoned
- 2003-06-23 WO PCT/US2003/019527 patent/WO2004000197A2/en active Search and Examination
- 2003-06-23 JP JP2004516037A patent/JP2005535622A/en active Pending
- 2003-06-23 MX MXPA04012877A patent/MXPA04012877A/en active IP Right Grant
- 2003-06-23 AU AU2003243696A patent/AU2003243696B2/en not_active Ceased
- 2003-06-23 EP EP03761197A patent/EP1553909A4/en not_active Withdrawn
- 2003-06-23 NZ NZ537744A patent/NZ537744A/en not_active IP Right Cessation
-
2011
- 2011-01-17 JP JP2011006565A patent/JP2011079864A/en active Pending
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5871781A (en) * | 1993-09-10 | 1999-02-16 | Fuisz Technologies Ltd. | Apparatus for making rapidly-dissolving dosage units |
Non-Patent Citations (1)
Title |
---|
See also references of EP1553909A4 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11957694B2 (en) | 2015-06-18 | 2024-04-16 | Estetra Srl | Orodispersible dosage unit containing an estetrol component |
US11964055B2 (en) | 2015-06-18 | 2024-04-23 | Estetra Srl | Orodispersible dosage unit containing an estetrol component |
Also Published As
Publication number | Publication date |
---|---|
CA2490365A1 (en) | 2003-12-31 |
NZ537744A (en) | 2010-03-26 |
AU2003243696A1 (en) | 2004-01-06 |
EP1553909A4 (en) | 2007-11-28 |
AU2003243696B2 (en) | 2008-10-09 |
JP2005535622A (en) | 2005-11-24 |
MXPA04012877A (en) | 2005-07-05 |
US7815937B2 (en) | 2010-10-19 |
EP1553909A2 (en) | 2005-07-20 |
JP2011079864A (en) | 2011-04-21 |
WO2004000197A2 (en) | 2003-12-31 |
US20030124184A1 (en) | 2003-07-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2004000197A3 (en) | Quick dissolve compositions and tablets based thereon | |
WO2001085257A3 (en) | Opioid antagonist compositions and dosage forms | |
ATE333265T1 (en) | RAPIDLY DISSOLVING SOLID DOSAGE FORMS FOR ORAL APPLICATION | |
HUP0002316A2 (en) | Flash-melt oral dosage formulation | |
WO2007074472A3 (en) | Mouth dissolving pharmaceutical composition and process for preparing the same using a high amount of silicon dioxide | |
HUP0402293A2 (en) | Orodispersible tablets containing fexofenadine, coated granules and process for its preparation | |
TW200505498A (en) | Sugar-free oral transmucosal solid dosage forms and uses thereof | |
WO2009043844A3 (en) | Orodispersible tablets | |
JP2012001557A (en) | Improved fast disintegrating tablet | |
RS20050239A (en) | Solid pharmaceutical formulations comprising telmisartan | |
WO2007009806A3 (en) | Solid dosage formulations of narcotic drugs having improved buccal adsorption | |
WO2004066910A8 (en) | Controlled release modifying complex and pharmaceutical compositions thereof | |
CA2447807A1 (en) | Abuse resistant pharmaceutical composition containing capsaicin | |
JP2008531681A (en) | Fast disintegrating preparation containing magnesium carbonate heavy | |
EA200000246A1 (en) | QUICKLY DISINTEGRATING METAL CELLULOSE TABLETS | |
HUP0402492A2 (en) | 5ht4 partial agonist pharmaceutical compositions | |
HUP0102676A2 (en) | Solid, quick dissolving pharmaceutical compositions containing cetrizine | |
MA27816A1 (en) | RAPIDLY HYDRODISPERSABLE DOMPERIDONE TABLETS | |
MY127350A (en) | Flash-melt oral dose formulations | |
HUP0301390A2 (en) | Oral pharmaceutical composition containing valsartan | |
WO2006053089A3 (en) | Methods and formulations for making pharmaceutical compositions containing bupropion | |
EA201001108A1 (en) | TABLETS DISPENSABLE IN THE Mouth OF THE TABLET, CONTAINING THE BASIS OF THE ESCITALOPRAM, AND METHOD OF THEIR RECEIVING | |
MXPA04003346A (en) | Flashmelt oral dosage formulation. | |
WO2003005967A3 (en) | Dual release levodopa ethyl ester and decarboxylase in controlled release core | |
WO2005004860A3 (en) | Novel solid pharmaceutical composition comprising amisulpride |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SC SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2490365 Country of ref document: CA |
|
WWE | Wipo information: entry into national phase |
Ref document number: PA/a/2004/012877 Country of ref document: MX |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2004516037 Country of ref document: JP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2006/KOLNP/2004 Country of ref document: IN |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2003243696 Country of ref document: AU |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2003761197 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 537744 Country of ref document: NZ |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
WWP | Wipo information: published in national office |
Ref document number: 2003761197 Country of ref document: EP |