WO2004012681A3 - Cancer vaccines containing epitopes of oncofetal antigen - Google Patents
Cancer vaccines containing epitopes of oncofetal antigen Download PDFInfo
- Publication number
- WO2004012681A3 WO2004012681A3 PCT/US2003/024518 US0324518W WO2004012681A3 WO 2004012681 A3 WO2004012681 A3 WO 2004012681A3 US 0324518 W US0324518 W US 0324518W WO 2004012681 A3 WO2004012681 A3 WO 2004012681A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- oncofetal antigen
- cancer vaccines
- vaccines containing
- containing epitopes
- fragments
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 2
- 102000036639 antigens Human genes 0.000 title abstract 2
- 108091007433 antigens Proteins 0.000 title abstract 2
- 229940022399 cancer vaccine Drugs 0.000 title 1
- 238000009566 cancer vaccine Methods 0.000 title 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 102000002297 Laminin Receptors Human genes 0.000 abstract 1
- 108010000851 Laminin Receptors Proteins 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/00118—Cancer antigens from embryonic or fetal origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA2492938A CA2492938C (en) | 2002-08-02 | 2003-08-04 | Cancer vaccines containing epitopes of oncofetal antigen |
ES03767221.9T ES2565578T3 (en) | 2002-08-02 | 2003-08-04 | Cancer vaccines containing oncofetal antigen epitopes |
AU2003258081A AU2003258081A1 (en) | 2002-08-02 | 2003-08-04 | Cancer vaccines containing epitopes of oncofetal antigen |
EP03767221.9A EP1538900B1 (en) | 2002-08-02 | 2003-08-04 | Cancer vaccines containing epitopes of oncofetal antigen |
US10/523,277 US7718762B2 (en) | 2002-08-02 | 2003-08-04 | Cancer vaccines containing epitopes of oncofetal antigen |
US12/462,514 US8709405B2 (en) | 2002-08-02 | 2009-08-05 | Cancer vaccines containing epitopes of oncofetal antigen |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40085102P | 2002-08-02 | 2002-08-02 | |
US60/400,851 | 2002-08-02 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10523277 A-371-Of-International | 2003-08-04 | ||
US12/462,514 Continuation US8709405B2 (en) | 2002-08-02 | 2009-08-05 | Cancer vaccines containing epitopes of oncofetal antigen |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004012681A2 WO2004012681A2 (en) | 2004-02-12 |
WO2004012681A3 true WO2004012681A3 (en) | 2004-11-11 |
Family
ID=31495892
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/024518 WO2004012681A2 (en) | 2002-08-02 | 2003-08-04 | Cancer vaccines containing epitopes of oncofetal antigen |
Country Status (6)
Country | Link |
---|---|
US (2) | US7718762B2 (en) |
EP (1) | EP1538900B1 (en) |
AU (1) | AU2003258081A1 (en) |
CA (1) | CA2492938C (en) |
ES (1) | ES2565578T3 (en) |
WO (1) | WO2004012681A2 (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080286312A1 (en) * | 2002-06-12 | 2008-11-20 | Gavish-Galilee Bio Applications Ltd. | Membrane-anchored beta2 microglobulincovalently linked to MHC class I peptide epitopes |
US20060003315A1 (en) * | 2002-06-12 | 2006-01-05 | Gavish-Galilee Bio Applications Ltd. | Membrane-anchored beta2 microglobulin covalently linked to mhc class 1 peptide epitopes |
ES2282355T3 (en) | 2002-10-11 | 2007-10-16 | Sentoclone Ab | CANCER IMMUNOTHERAPY. |
US20080206270A1 (en) * | 2004-07-08 | 2008-08-28 | Minev Boris R | Enhancing Class I Antigen Presentation With Synthetic Sequences |
EP1717245B1 (en) * | 2005-04-26 | 2011-06-08 | Immatics Biotechnologies GmbH | T-cell epitopes from the oncofetal antigen-immature laminin receptor protein and medical uses thereof |
EP1966369B1 (en) | 2005-12-21 | 2010-10-06 | Sentoclone AB | Method for expansion of tumour-reactive t-lymphocytes for immunotherapy of patients with cancer |
US8211424B2 (en) | 2005-12-21 | 2012-07-03 | Sentoclone International Ab | Method for treating malignant melanoma |
US8211425B2 (en) | 2005-12-21 | 2012-07-03 | Sentoclone International Ab | Method for treating disseminated cancer |
US8101173B2 (en) | 2005-12-21 | 2012-01-24 | Sentoclone International Ab | Method for treating urinary bladder cancer |
EP1981533A1 (en) * | 2006-02-06 | 2008-10-22 | Medizinische Universität Wien | Vaccine and antigen mimotopes against cancerous diseases associated with the carcinoembryonic antigen cea |
CA2597840A1 (en) | 2006-09-01 | 2008-03-01 | Government Of The United States Of America, As Represented By The Secret Ary, Department Of Health And Human Services | Methods and compositions for the treatment and prevention of cancer |
WO2010111669A1 (en) * | 2009-03-26 | 2010-09-30 | Quantum Immunologics, Inc. | Oncofetal antigen/immature laminin receptor peptides for the sensitization of dendritic cells for cancer therapy |
WO2010111671A1 (en) * | 2009-03-26 | 2010-09-30 | Quantum Immunologics, Inc. | Oncofetal antigen/immature laminin receptor antibodies for diagnostic and clinical applications |
US20130052211A1 (en) * | 2009-07-09 | 2013-02-28 | South Alabama Medical Science | Vaccines with oncofetal antigen/ilrp-loaded autologous dendritic cells and uses thereof |
EP2330122A1 (en) * | 2009-12-02 | 2011-06-08 | Asklepios Kliniken Hamburg Gmbh | OFA/iLRP derived modified peptide |
EP3351641A1 (en) | 2011-04-08 | 2018-07-25 | Tufts Medical Center, Inc. | Pepducin design and use |
GB201519557D0 (en) * | 2015-11-05 | 2015-12-23 | Univ Witwatersrand Jhb | Compounds for use in the treatment of telomere related diseases and/or telomere related medical conditions |
WO2017083618A1 (en) | 2015-11-13 | 2017-05-18 | Oasis Pharmaceuticals, LLC | Protease-activated receptor-2 modulators |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6080725A (en) * | 1997-05-20 | 2000-06-27 | Galenica Pharmaceuticals, Inc. | Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6335174B1 (en) * | 1996-04-05 | 2002-01-01 | South Alabama Medical Science Foundation | Oncofetal antigen specific t-lymphocyte mediated immune response: manipulation and uses of oncofetal antigen specific CD4, CD8 cytotoxic and suppressor T cells and interleukin-10 |
WO1998053048A1 (en) * | 1997-05-21 | 1998-11-26 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Methods and compositions for making dendritic cells from expanded populations of monocytes and for activating t cells |
US6602510B1 (en) * | 2000-04-05 | 2003-08-05 | Epimmune Inc. | HLA class I A2 tumor associated antigen peptides and vaccine compositions |
DE10041515A1 (en) | 2000-08-24 | 2002-03-14 | Gerold Schuler | Process for the production of ready-to-use, antigen-loaded or unloaded, cryopreserved mature dendritic cells |
US7118753B2 (en) * | 2002-02-08 | 2006-10-10 | Anawrahta Biotech Co., Ltd. | Enhancing cell-based immunotherapy |
AU2003249382A1 (en) | 2002-06-26 | 2004-01-19 | Pharmablood Inc. | A method and composition to elicit an effective autologous antitumoral immune response in a patient |
EP1717245B1 (en) | 2005-04-26 | 2011-06-08 | Immatics Biotechnologies GmbH | T-cell epitopes from the oncofetal antigen-immature laminin receptor protein and medical uses thereof |
-
2003
- 2003-08-04 WO PCT/US2003/024518 patent/WO2004012681A2/en not_active Application Discontinuation
- 2003-08-04 ES ES03767221.9T patent/ES2565578T3/en not_active Expired - Lifetime
- 2003-08-04 US US10/523,277 patent/US7718762B2/en not_active Expired - Fee Related
- 2003-08-04 EP EP03767221.9A patent/EP1538900B1/en not_active Expired - Lifetime
- 2003-08-04 CA CA2492938A patent/CA2492938C/en not_active Expired - Fee Related
- 2003-08-04 AU AU2003258081A patent/AU2003258081A1/en not_active Abandoned
-
2009
- 2009-08-05 US US12/462,514 patent/US8709405B2/en not_active Expired - Fee Related
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6080725A (en) * | 1997-05-20 | 2000-06-27 | Galenica Pharmaceuticals, Inc. | Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof |
Non-Patent Citations (3)
Title |
---|
ARMSTRONG A:C. ET AL: "Vaccines in Oncology: Background and clinical potential", BRITISH JOURNAL OF RADIOLOGY, vol. 74, no. 887, November 2001 (2001-11-01), pages 991 - 1002, XP002981880 * |
COGGIN JR ET AL: "37 Kilodalton oncofetal antigen protein and immature laminin receptor protein are identical, universal T-cell inducing immunogens on primary rodent and human cancers", ANTICANCER RES., vol. 19, no. 6C, November 1999 (1999-11-01) - December 1999 (1999-12-01), pages 5535 - 5542, XP002981891 * |
NUKAYA I. ET AL: "Identification of HLA-A24 epitope peptides of carcinoembryonic antigen which induce tumor-reactive cytotoxic T lymphocyte", INT. J. CANCER, vol. 80, no. 1, January 1999 (1999-01-01), pages 92 - 97, XP002981879 * |
Also Published As
Publication number | Publication date |
---|---|
CA2492938C (en) | 2012-05-22 |
CA2492938A1 (en) | 2004-02-12 |
EP1538900A2 (en) | 2005-06-15 |
US8709405B2 (en) | 2014-04-29 |
AU2003258081A8 (en) | 2004-02-23 |
WO2004012681A2 (en) | 2004-02-12 |
US20100183643A1 (en) | 2010-07-22 |
US20060165709A1 (en) | 2006-07-27 |
ES2565578T3 (en) | 2016-04-05 |
US7718762B2 (en) | 2010-05-18 |
EP1538900A4 (en) | 2008-09-24 |
EP1538900B1 (en) | 2016-01-06 |
AU2003258081A1 (en) | 2004-02-23 |
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