WO2004030678A8 - Polymer compositions containing bioactive agents and methods for their use - Google Patents

Polymer compositions containing bioactive agents and methods for their use

Info

Publication number
WO2004030678A8
WO2004030678A8 PCT/US2003/029971 US0329971W WO2004030678A8 WO 2004030678 A8 WO2004030678 A8 WO 2004030678A8 US 0329971 W US0329971 W US 0329971W WO 2004030678 A8 WO2004030678 A8 WO 2004030678A8
Authority
WO
WIPO (PCT)
Prior art keywords
methods
compositions containing
polymer compositions
bioactive agents
containing bioactive
Prior art date
Application number
PCT/US2003/029971
Other languages
French (fr)
Other versions
WO2004030678A3 (en
WO2004030678A2 (en
Inventor
Antwerp William P Van
Original Assignee
Medtronic Minimed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Minimed Inc filed Critical Medtronic Minimed Inc
Priority to EP20030754849 priority Critical patent/EP1551428A4/en
Priority to AU2003272654A priority patent/AU2003272654A1/en
Publication of WO2004030678A2 publication Critical patent/WO2004030678A2/en
Publication of WO2004030678A3 publication Critical patent/WO2004030678A3/en
Publication of WO2004030678A8 publication Critical patent/WO2004030678A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/727—Heparin; Heparan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31551—Of polyamidoester [polyurethane, polyisocyanate, polycarbamate, etc.]

Abstract

Embodiments of the invention provide polymer coated implantable medical devices having a bioactive material posited in or on at least a portion of the coating layer, wherein the coating layer provides for the controlled release of the bioactive material from the coating layer. Preferably, the medical device is an intravascular stent.
PCT/US2003/029971 2002-09-30 2003-09-24 Polymer compositions containing bioactive agents and methods for their use WO2004030678A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP20030754849 EP1551428A4 (en) 2002-09-30 2003-09-24 Polymer compositions containing bioactive agents and methods for their use
AU2003272654A AU2003272654A1 (en) 2002-09-30 2003-09-24 Polymer compositions containing bioactive agents and methods for their use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/260,786 2002-09-30
US10/260,786 US6770729B2 (en) 2002-09-30 2002-09-30 Polymer compositions containing bioactive agents and methods for their use

Publications (3)

Publication Number Publication Date
WO2004030678A2 WO2004030678A2 (en) 2004-04-15
WO2004030678A3 WO2004030678A3 (en) 2004-05-06
WO2004030678A8 true WO2004030678A8 (en) 2004-06-10

Family

ID=22990618

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/029971 WO2004030678A2 (en) 2002-09-30 2003-09-24 Polymer compositions containing bioactive agents and methods for their use

Country Status (4)

Country Link
US (1) US6770729B2 (en)
EP (1) EP1551428A4 (en)
AU (1) AU2003272654A1 (en)
WO (1) WO2004030678A2 (en)

Families Citing this family (245)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7899511B2 (en) * 2004-07-13 2011-03-01 Dexcom, Inc. Low oxygen in vivo analyte sensor
US20050033132A1 (en) 1997-03-04 2005-02-10 Shults Mark C. Analyte measuring device
US9155496B2 (en) 1997-03-04 2015-10-13 Dexcom, Inc. Low oxygen in vivo analyte sensor
US20030040790A1 (en) 1998-04-15 2003-02-27 Furst Joseph G. Stent coating
US20020099438A1 (en) * 1998-04-15 2002-07-25 Furst Joseph G. Irradiated stent coating
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8070796B2 (en) 1998-07-27 2011-12-06 Icon Interventional Systems, Inc. Thrombosis inhibiting graft
US7967855B2 (en) 1998-07-27 2011-06-28 Icon Interventional Systems, Inc. Coated medical device
US7013182B1 (en) * 2000-05-04 2006-03-14 Cardiac Pacemakers, Inc. Conductive polymer sheath on defibrillator shocking coils
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
US7041468B2 (en) 2001-04-02 2006-05-09 Therasense, Inc. Blood glucose tracking apparatus and methods
US7727221B2 (en) 2001-06-27 2010-06-01 Cardiac Pacemakers Inc. Method and device for electrochemical formation of therapeutic species in vivo
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
US8364229B2 (en) * 2003-07-25 2013-01-29 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US20050008828A1 (en) * 2002-07-25 2005-01-13 Trustees Of Stevens Institute Of Technology Patterned polymer microgel and method of forming same
US8016881B2 (en) 2002-07-31 2011-09-13 Icon Interventional Systems, Inc. Sutures and surgical staples for anastamoses, wound closures, and surgical closures
EP2322798A1 (en) 2002-10-09 2011-05-18 Abbott Diabetes Care Inc. Device and method for delivering medical fluids using a shape memory alloy
US7727181B2 (en) 2002-10-09 2010-06-01 Abbott Diabetes Care Inc. Fluid delivery device with autocalibration
US7993108B2 (en) 2002-10-09 2011-08-09 Abbott Diabetes Care Inc. Variable volume, shape memory actuated insulin dispensing pump
CA2503193A1 (en) * 2002-10-22 2004-05-06 The Biomerix Corporation Method and system for intravesicular delivery of therapeutic agents
US20040106163A1 (en) * 2002-11-12 2004-06-03 Workman Jerome James Non-invasive measurement of analytes
AU2003287735A1 (en) * 2002-11-12 2004-06-03 Argose, Inc. Non-invasive measurement of analytes
US6992127B2 (en) * 2002-11-25 2006-01-31 Ast Products, Inc. Polymeric coatings containing a pH buffer agent
US7811231B2 (en) 2002-12-31 2010-10-12 Abbott Diabetes Care Inc. Continuous glucose monitoring system and methods of use
US8771183B2 (en) 2004-02-17 2014-07-08 Abbott Diabetes Care Inc. Method and system for providing data communication in continuous glucose monitoring and management system
JP2004222953A (en) * 2003-01-22 2004-08-12 Kanegafuchi Chem Ind Co Ltd Indwelling stent
US20040180131A1 (en) * 2003-03-14 2004-09-16 Medtronic Ave. Stent coating method
CA2523267C (en) 2003-04-23 2013-09-03 Biovalve Technologies, Inc. Hydraulically actuated pump for long duration medicament administration
US7679407B2 (en) 2003-04-28 2010-03-16 Abbott Diabetes Care Inc. Method and apparatus for providing peak detection circuitry for data communication systems
US20040220534A1 (en) * 2003-04-29 2004-11-04 Martens Paul W. Medical device with antimicrobial layer
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
CN100558321C (en) * 2003-06-16 2009-11-11 南洋理工大学 Polymer Scaffold And Its Manufacturing Methods
US20070173709A1 (en) * 2005-04-08 2007-07-26 Petisce James R Membranes for an analyte sensor
US9763609B2 (en) 2003-07-25 2017-09-19 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US7651596B2 (en) 2005-04-08 2010-01-26 Dexcom, Inc. Cellulosic-based interference domain for an analyte sensor
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
CA2541974A1 (en) * 2003-10-02 2005-04-14 Trustees Of Stevens Institute Of Technology Capsules of multilayered neutral polymer films associated by hydrogen bonding
US7299082B2 (en) 2003-10-31 2007-11-20 Abbott Diabetes Care, Inc. Method of calibrating an analyte-measurement device, and associated methods, devices and systems
AU2004293463A1 (en) * 2003-11-20 2005-06-09 Angiotech International Ag Implantable sensors and implantable pumps and anti-scarring agents
US7211108B2 (en) * 2004-01-23 2007-05-01 Icon Medical Corp. Vascular grafts with amphiphilic block copolymer coatings
US7699964B2 (en) 2004-02-09 2010-04-20 Abbott Diabetes Care Inc. Membrane suitable for use in an analyte sensor, analyte sensor, and associated method
US8165651B2 (en) * 2004-02-09 2012-04-24 Abbott Diabetes Care Inc. Analyte sensor, and associated system and method employing a catalytic agent
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
WO2006014425A1 (en) 2004-07-02 2006-02-09 Biovalve Technologies, Inc. Methods and devices for delivering glp-1 and uses thereof
US7572600B2 (en) * 2004-08-04 2009-08-11 Chemocentryx, Inc. Enzymatic activities in chemokine-mediated inflammation
WO2006047289A2 (en) * 2004-10-21 2006-05-04 Medtronic, Inc. Angiotensin-(1-7) eluting polymer-coated medical device to reduce restenosis and improve endothelial cell function
JP2006177803A (en) * 2004-12-22 2006-07-06 Seiko Epson Corp Liquid discharge method and microarray manufacturing method
WO2006110197A2 (en) 2005-03-03 2006-10-19 Icon Medical Corp. Polymer biodegradable medical device
US7540995B2 (en) 2005-03-03 2009-06-02 Icon Medical Corp. Process for forming an improved metal alloy stent
US9107899B2 (en) 2005-03-03 2015-08-18 Icon Medical Corporation Metal alloys for medical devices
US20060200048A1 (en) * 2005-03-03 2006-09-07 Icon Medical Corp. Removable sheath for device protection
WO2006102412A2 (en) 2005-03-21 2006-09-28 Abbott Diabetes Care, Inc. Method and system for providing integrated medication infusion and analyte monitoring system
US20060249381A1 (en) * 2005-05-05 2006-11-09 Petisce James R Cellulosic-based resistance domain for an analyte sensor
US8744546B2 (en) * 2005-05-05 2014-06-03 Dexcom, Inc. Cellulosic-based resistance domain for an analyte sensor
US8112240B2 (en) 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
US20060253085A1 (en) * 2005-05-06 2006-11-09 Medtronic Minimed, Inc. Dual insertion set
WO2006124726A2 (en) * 2005-05-12 2006-11-23 The General Hospital Corporation Novel biotinylated compositions
US7768408B2 (en) 2005-05-17 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing data management in data monitoring system
US7620437B2 (en) 2005-06-03 2009-11-17 Abbott Diabetes Care Inc. Method and apparatus for providing rechargeable power in data monitoring and management systems
US20070014830A1 (en) * 2005-06-08 2007-01-18 Tijsma Edze J Drug-releasing sinus stent
US7777035B2 (en) 2005-06-22 2010-08-17 Chemocentryx, Inc. Azaindazole compounds and methods of use
US20070009564A1 (en) * 2005-06-22 2007-01-11 Mcclain James B Drug/polymer composite materials and methods of making the same
CA2615452C (en) 2005-07-15 2015-03-31 Micell Technologies, Inc. Polymer coatings containing drug powder of controlled morphology
US20090062909A1 (en) * 2005-07-15 2009-03-05 Micell Technologies, Inc. Stent with polymer coating containing amorphous rapamycin
US20070184413A1 (en) * 2005-09-28 2007-08-09 Essential Dental Systems, Inc. Pre-coated root canal filling point
US7583190B2 (en) 2005-10-31 2009-09-01 Abbott Diabetes Care Inc. Method and apparatus for providing data communication in data monitoring and management systems
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
US20070110788A1 (en) * 2005-11-14 2007-05-17 Hissong James B Injectable formulation capable of forming a drug-releasing device
US8353881B2 (en) * 2005-12-28 2013-01-15 Abbott Diabetes Care Inc. Infusion sets for the delivery of a therapeutic substance to a patient
US20070154518A1 (en) * 2005-12-29 2007-07-05 Robert Falotico Photoactive biocompatible coating composition
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US9757061B2 (en) 2006-01-17 2017-09-12 Dexcom, Inc. Low oxygen in vivo analyte sensor
US8092819B2 (en) * 2006-01-27 2012-01-10 Cook Medical Technologies LLC. Implantable medical device coated with a bioactive agent
US8344966B2 (en) 2006-01-31 2013-01-01 Abbott Diabetes Care Inc. Method and system for providing a fault tolerant display unit in an electronic device
US8089029B2 (en) 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
EP1832289A3 (en) * 2006-03-08 2007-12-12 Sahajanand Medical Technologies PVT. ltd Compositions and coatings for implantable medical devices
US7881808B2 (en) * 2006-03-29 2011-02-01 Cardiac Pacemakers, Inc. Conductive polymeric coating with optional biobeneficial topcoat for a medical lead
CN103239773B (en) 2006-03-30 2015-08-26 瓦莱里塔斯公司 Multi-cartridge fluid delivery device
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
CA2996768C (en) 2006-04-26 2020-12-08 Micell Technologies, Inc. Coatings containing multiple drugs
US7993675B2 (en) * 2006-05-10 2011-08-09 Medtronic Xomed, Inc. Solvating system and sealant for medical use in the sinuses and nasal passages
US7959943B2 (en) * 2006-05-10 2011-06-14 Medtronics Xomed, Inc. Solvating system and sealant for medical use in the middle or inner ear
US7976873B2 (en) * 2006-05-10 2011-07-12 Medtronic Xomed, Inc. Extracellular polysaccharide solvating system for treatment of bacterial ear conditions
EP2020956A2 (en) * 2006-05-26 2009-02-11 Nanyang Technological University Implantable article, method of forming same and method for reducing thrombogenicity
WO2007143225A2 (en) 2006-06-07 2007-12-13 Abbott Diabetes Care, Inc. Analyte monitoring system and method
US20070298067A1 (en) * 2006-06-22 2007-12-27 Boston Scientific Scimed, Inc. Control release drug coating for medical devices
WO2008005297A2 (en) * 2006-06-29 2008-01-10 Massachusetts Institute Of Technology Coating of devices with effector compounds
US7794495B2 (en) * 2006-07-17 2010-09-14 Advanced Cardiovascular Systems, Inc. Controlled degradation of stents
WO2008011612A2 (en) 2006-07-20 2008-01-24 Orbusneich Medical, Inc. Bioabsorbable polymeric medical device
EP3009477B1 (en) 2006-07-20 2024-01-24 Orbusneich Medical Pte. Ltd Bioabsorbable polymeric composition for a medical device
US8460364B2 (en) * 2006-07-20 2013-06-11 Orbusneich Medical, Inc. Bioabsorbable polymeric medical device
CA2658523C (en) 2006-07-31 2012-06-12 Activesite Pharmaceuticals, Inc. Inhibitors of plasma kallikrein
JP2009545407A (en) 2006-08-02 2009-12-24 ボストン サイエンティフィック サイムド，インコーポレイテッド End prosthesis with 3D decomposition control
WO2008034013A2 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Medical devices and methods of making the same
WO2008034066A1 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Bioerodible endoprostheses and methods of making the same
DE602007011114D1 (en) 2006-09-15 2011-01-20 Boston Scient Scimed Inc BIODEGRADABLE ENDOPROTHESIS WITH BIOSTABILES INORGANIC LAYERS
JP2010503489A (en) 2006-09-15 2010-02-04 ボストン サイエンティフィック リミテッド Biodegradable endoprosthesis and method for producing the same
WO2008036548A2 (en) 2006-09-18 2008-03-27 Boston Scientific Limited Endoprostheses
WO2008042909A2 (en) 2006-10-02 2008-04-10 Micell Technologies Inc. Surgical sutures having increased strength
EP2073754A4 (en) * 2006-10-20 2012-09-26 Orbusneich Medical Inc Bioabsorbable polymeric composition and medical device background
US7959942B2 (en) * 2006-10-20 2011-06-14 Orbusneich Medical, Inc. Bioabsorbable medical device with coating
EP2086599A4 (en) * 2006-10-20 2012-11-28 Orbusneich Medical Inc Bioabsorbable medical device with coating
CA2667228C (en) * 2006-10-23 2015-07-14 Micell Technologies, Inc. Holder for electrically charging a substrate during coating
WO2008052179A2 (en) * 2006-10-27 2008-05-02 Medtronic, Inc. Angiotensin (1-7) eluting stent
US8579853B2 (en) 2006-10-31 2013-11-12 Abbott Diabetes Care Inc. Infusion devices and methods
ES2506144T3 (en) 2006-12-28 2014-10-13 Boston Scientific Limited Bioerodible endoprosthesis and their manufacturing procedure
US20080161666A1 (en) * 2006-12-29 2008-07-03 Abbott Diabetes Care, Inc. Analyte devices and methods
CA2679712C (en) 2007-01-08 2016-11-15 Micell Technologies, Inc. Stents having biodegradable layers
US11426494B2 (en) 2007-01-08 2022-08-30 MT Acquisition Holdings LLC Stents having biodegradable layers
WO2008097511A2 (en) * 2007-02-07 2008-08-14 Cook Incorporated Medical device coatings for releasing a therapeutic agent at multiple rates
US8088095B2 (en) * 2007-02-08 2012-01-03 Medtronic Xomed, Inc. Polymeric sealant for medical use
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
US8093039B2 (en) * 2007-04-10 2012-01-10 The Trustees Of The Stevens Institute Of Technology Surfaces differentially adhesive to eukaryotic cells and non-eukaryotic cells
CA2684482C (en) * 2007-04-17 2014-08-12 Micell Technologies, Inc. Stents having biodegradable layers
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US20200037874A1 (en) 2007-05-18 2020-02-06 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
BRPI0811849A8 (en) 2007-05-22 2019-01-15 Chemocentryx Inc compound, pharmaceutical composition, and methods for preparing the compound and for treating ccr1-mediated diseases or conditions
AU2008256684B2 (en) * 2007-05-25 2012-06-14 Micell Technologies, Inc. Polymer films for medical device coating
WO2008154312A1 (en) 2007-06-08 2008-12-18 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US7984738B2 (en) * 2007-06-26 2011-07-26 Emabond Solutions Llc Temperature controlled polymer composition for inductive control heating using electrical conductive and magnetic particles
US20110130822A1 (en) * 2007-07-20 2011-06-02 Orbusneich Medical, Inc. Bioabsorbable Polymeric Compositions and Medical Devices
US7747302B2 (en) * 2007-08-08 2010-06-29 Lifescan, Inc. Method for integrating facilitated blood flow and blood analyte monitoring
US20090043183A1 (en) * 2007-08-08 2009-02-12 Lifescan, Inc. Integrated stent and blood analyte monitoring system
US9968742B2 (en) * 2007-08-29 2018-05-15 Medtronic Minimed, Inc. Combined sensor and infusion set using separated sites
US20120046533A1 (en) 2007-08-29 2012-02-23 Medtronic Minimed, Inc. Combined sensor and infusion sets
US8052745B2 (en) 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
US9452258B2 (en) 2007-10-09 2016-09-27 Dexcom, Inc. Integrated insulin delivery system with continuous glucose sensor
WO2009051780A1 (en) * 2007-10-19 2009-04-23 Micell Technologies, Inc. Drug coated stents
US20090247984A1 (en) * 2007-10-24 2009-10-01 Masimo Laboratories, Inc. Use of microneedles for small molecule metabolite reporter delivery
US8512731B2 (en) * 2007-11-13 2013-08-20 Medtronic Minimed, Inc. Antimicrobial coatings for medical devices and methods for making and using them
WO2009102795A1 (en) * 2008-02-15 2009-08-20 University Of Southern Mississippi Monomers and polymers with covalently-attached active ingredients
US20090299156A1 (en) * 2008-02-20 2009-12-03 Dexcom, Inc. Continuous medicament sensor system for in vivo use
US8583204B2 (en) 2008-03-28 2013-11-12 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8682408B2 (en) 2008-03-28 2014-03-25 Dexcom, Inc. Polymer membranes for continuous analyte sensors
CN102047101A (en) * 2008-03-28 2011-05-04 德克斯康公司 Polymer membranes for continuous analyte sensors
US11730407B2 (en) 2008-03-28 2023-08-22 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US20090259118A1 (en) * 2008-03-31 2009-10-15 Abbott Diabetes Care Inc. Shallow Implantable Analyte Sensor with Rapid Physiological Response
EP2271294B1 (en) 2008-04-17 2018-03-28 Micell Technologies, Inc. Stents having bioabsorbable layers
US7998192B2 (en) 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
EP2303254B1 (en) 2008-06-12 2019-10-30 Medtronic Xomed, Inc. Product for treating chronic wounds with an extracellular polymeric substance solvating system
US8834446B2 (en) * 2008-06-12 2014-09-16 DePuy Synthes Products, LLC Pulsatile flux drug delivery
IL192262A (en) 2008-06-17 2016-05-31 Z H T Eng Equipment And Tech Ltd Polymer adapted to release bioactive agents in vivo, pharmaceutical composition comprising it and method of preparation thereof
US8206635B2 (en) 2008-06-20 2012-06-26 Amaranth Medical Pte. Stent fabrication via tubular casting processes
US10898620B2 (en) 2008-06-20 2021-01-26 Razmodics Llc Composite stent having multi-axial flexibility and method of manufacture thereof
US8206636B2 (en) 2008-06-20 2012-06-26 Amaranth Medical Pte. Stent fabrication via tubular casting processes
JP2011528275A (en) * 2008-07-17 2011-11-17 ミセル テクノロジーズ，インク． Drug delivery medical device
US7985252B2 (en) 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
ES2536884T3 (en) 2008-09-11 2015-05-29 Chemocentryx, Inc. 4-Amino-3- (imidazolyl) pyrazol [3,4-d] pyrimidines
US8382824B2 (en) 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
WO2010042854A1 (en) * 2008-10-10 2010-04-15 Orbusneich Medical, Inc. Bioabsorbable polymeric medical device
WO2010042952A1 (en) * 2008-10-11 2010-04-15 Orbusneich Medical, Inc. Bioabsorbable polymeric compositions and medical devices
US8834913B2 (en) * 2008-12-26 2014-09-16 Battelle Memorial Institute Medical implants and methods of making medical implants
EP2385960B1 (en) 2009-01-12 2020-03-11 University Of Massachusetts Lowell Polyisobutylene-based polyurethanes
AU2010205223B2 (en) * 2009-01-16 2013-03-14 Toyo Suisan Kaisha, Ltd. Compound retained in tumor
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US8560082B2 (en) 2009-01-30 2013-10-15 Abbott Diabetes Care Inc. Computerized determination of insulin pump therapy parameters using real time and retrospective data processing
EP2403546A2 (en) 2009-03-02 2012-01-11 Boston Scientific Scimed, Inc. Self-buffering medical implants
US20100239635A1 (en) * 2009-03-23 2010-09-23 Micell Technologies, Inc. Drug delivery medical device
CA2756307C (en) * 2009-03-23 2017-08-08 Micell Technologies, Inc. Peripheral stents having layers and reinforcement fibers
WO2010111238A2 (en) * 2009-03-23 2010-09-30 Micell Technologies, Inc. Improved biodegradable polymers
US20100247600A1 (en) * 2009-03-24 2010-09-30 Warsaw Orthopedic, Inc. Therapeutic drug eluting implant cover and method of making the same
EP2236520A1 (en) * 2009-03-31 2010-10-06 Leukocare Ag Stabilizing composition for immobilized biomolecules
CN102481195B (en) * 2009-04-01 2015-03-25 米歇尔技术公司 Drug delivery medical device
US9078712B2 (en) 2009-04-15 2015-07-14 Warsaw Orthopedic, Inc. Preformed drug-eluting device to be affixed to an anterior spinal plate
US9414864B2 (en) 2009-04-15 2016-08-16 Warsaw Orthopedic, Inc. Anterior spinal plate with preformed drug-eluting device affixed thereto
WO2010121187A2 (en) 2009-04-17 2010-10-21 Micell Techologies, Inc. Stents having controlled elution
US9226701B2 (en) 2009-04-28 2016-01-05 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
WO2010129375A1 (en) 2009-04-28 2010-11-11 Abbott Diabetes Care Inc. Closed loop blood glucose control algorithm analysis
US9289540B2 (en) * 2009-05-08 2016-03-22 Greatbatch Ltd. Surface modification for coating
US9184490B2 (en) 2009-05-29 2015-11-10 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
EP2453834A4 (en) 2009-07-16 2014-04-16 Micell Technologies Inc Drug delivery medical device
EP3936032A1 (en) 2009-07-23 2022-01-12 Abbott Diabetes Care, Inc. Real time management of data relating to physiological control of glucose levels
AU2010284137B2 (en) 2009-08-21 2014-11-27 Cardiac Pacemakers, Inc. Crosslinkable polyisobutylene-based polymers and medical devices containing the same
WO2011026148A1 (en) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Analyte monitoring system and methods for managing power and noise
US9314195B2 (en) 2009-08-31 2016-04-19 Abbott Diabetes Care Inc. Analyte signal processing device and methods
US8374704B2 (en) 2009-09-02 2013-02-12 Cardiac Pacemakers, Inc. Polyisobutylene urethane, urea and urethane/urea copolymers and medical leads containing the same
US8644952B2 (en) 2009-09-02 2014-02-04 Cardiac Pacemakers, Inc. Medical devices including polyisobutylene based polymers and derivatives thereof
US8753708B2 (en) 2009-09-02 2014-06-17 Cardiac Pacemakers, Inc. Solventless method for forming a coating on a medical electrical lead body
WO2011041469A1 (en) 2009-09-29 2011-04-07 Abbott Diabetes Care Inc. Method and apparatus for providing notification function in analyte monitoring systems
EP2501431B1 (en) * 2009-11-19 2020-01-08 Wellinq Medical B.V. Narrow profile composition-releasing expandable medical balloon catheter
SG181811A1 (en) 2009-12-18 2012-07-30 Activesite Pharmaceuticals Inc Prodrugs of inhibitors of plasma kallikrein
US11369498B2 (en) 2010-02-02 2022-06-28 MT Acquisition Holdings LLC Stent and stent delivery system with improved deliverability
US8398916B2 (en) 2010-03-04 2013-03-19 Icon Medical Corp. Method for forming a tubular medical device
US10448872B2 (en) 2010-03-16 2019-10-22 Medtronic Minimed, Inc. Analyte sensor apparatuses having improved electrode configurations and methods for making and using them
US8668732B2 (en) 2010-03-23 2014-03-11 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US8795762B2 (en) 2010-03-26 2014-08-05 Battelle Memorial Institute System and method for enhanced electrostatic deposition and surface coatings
WO2011133655A1 (en) 2010-04-22 2011-10-27 Micell Technologies, Inc. Stents and other devices having extracellular matrix coating
US9215995B2 (en) 2010-06-23 2015-12-22 Medtronic Minimed, Inc. Sensor systems having multiple probes and electrode arrays
CA2805631C (en) 2010-07-16 2018-07-31 Micell Technologies, Inc. Drug delivery medical device
EP2697196A1 (en) 2011-04-13 2014-02-19 Activesite Pharmaceuticals, Inc. Prodrugs of inhibitors of plasma kallikrein
WO2012166819A1 (en) 2011-05-31 2012-12-06 Micell Technologies, Inc. System and process for formation of a time-released, drug-eluting transferable coating
CA2841360A1 (en) 2011-07-15 2013-01-24 Micell Technologies, Inc. Drug delivery medical device
EP2771068B1 (en) * 2011-10-03 2021-05-05 Metuas Medikal Saglik Hizmetleri Danismanlik Ihracat Ithalat Limited Sirketi Magnetic diffusional patch
US10188772B2 (en) 2011-10-18 2019-01-29 Micell Technologies, Inc. Drug delivery medical device
US9980669B2 (en) 2011-11-07 2018-05-29 Abbott Diabetes Care Inc. Analyte monitoring device and methods
WO2013103514A1 (en) 2012-01-04 2013-07-11 The Trustees Of The Stevens Institute Of Technology Clay-containing thin films as carriers of absorbed molecules
BR112014032559A2 (en) 2012-06-25 2017-06-27 Bioengineering Laboratories Llc enzyme electrode
EP3441467A3 (en) 2012-08-31 2019-04-24 The General Hospital Corporation Biotin complexes for treatment and diagnosis of alzheimer's disease
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
US9926399B2 (en) 2012-11-21 2018-03-27 University Of Massachusetts High strength polyisobutylene polyurethanes
MX2015007051A (en) 2012-12-07 2016-01-12 Chemocentryx Inc Diazole lactams.
WO2014100735A2 (en) 2012-12-21 2014-06-26 Chemocentryx, Inc. Diazole amides
KR20150143476A (en) 2013-03-12 2015-12-23 미셀 테크놀로지즈, 인코포레이티드 Bioabsorbable biomedical implants
KR102079613B1 (en) 2013-05-15 2020-02-20 미셀 테크놀로지즈, 인코포레이티드 Bioabsorbable biomedical implants
WO2015076908A2 (en) 2013-09-13 2015-05-28 Brandeis University Polymeric materials having active cross-linkers, methods for making them, and use thereof
MX2016007128A (en) 2013-12-02 2016-08-11 Chemocentryx Inc Ccr6 compounds.
CA2933166C (en) 2013-12-31 2020-10-27 Abbott Diabetes Care Inc. Self-powered analyte sensor and devices using the same
MX2020013059A (en) 2014-03-07 2022-10-07 Biocryst Pharm Inc Human plasma kallikrein inhibitors.
BR112016030273A8 (en) 2014-06-24 2021-05-18 Icon Medical Corp medical device and method of forming said device
JP6916171B2 (en) 2015-10-01 2021-08-11 バイオクリスト ファーマスーティカルズ，インコーポレイテッドＢｉｏｃｒｙｓｔ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． Human plasma kallikrein inhibitor
TWI734715B (en) 2015-11-19 2021-08-01 美商卡默森屈有限公司 Modulators of chemokine receptors
TW202222786A (en) 2016-02-01 2022-06-16 美商百歐克斯製藥公司 Benzopyrazole compounds and analogues thereof
US11766506B2 (en) 2016-03-04 2023-09-26 Mirus Llc Stent device for spinal fusion
WO2018034849A1 (en) 2016-08-19 2018-02-22 The Procter & Gamble Company Polymeric materials and articles manufactured there from
IL266223B2 (en) 2016-10-31 2024-04-01 Biocryst Pharmaceuticals Inc Prodrugs of kallikrein inhibitors
WO2018165273A1 (en) 2017-03-07 2018-09-13 Cardiac Pacemakers, Inc. Hydroboration/oxidation of allyl-terminated polyisobutylene
AR112027A1 (en) 2017-06-15 2019-09-11 Biocryst Pharm Inc ALK 2 KINASE INHIBITORS CONTAINING IMIDAZOLE
CN110997746B (en) 2017-08-17 2021-12-28 心脏起搏器股份公司 Photocrosslinked polymers for enhanced durability
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
US20190120785A1 (en) 2017-10-24 2019-04-25 Dexcom, Inc. Pre-connected analyte sensors
EP3740253B1 (en) 2018-01-17 2023-08-16 Cardiac Pacemakers, Inc. End-capped polyisobutylene polyurethane
TW202010742A (en) 2018-04-06 2020-03-16 美商百歐克斯製藥公司 Substituted benzofuran, benzopyrrole,benzothiophene, and structurally related complement inhibitors
US20190309163A1 (en) * 2018-04-10 2019-10-10 The Procter & Gamble Company Polymeric Materials and Articles Manufactured There From
US11723875B2 (en) 2018-04-10 2023-08-15 The Procter & Gamble Company Polymeric materials and articles manufactured there from
KR20220058530A (en) 2019-07-08 2022-05-09 레졸루트 인크 Method for the preparation of plasma kallikrein inhibitors
PE20221009A1 (en) 2019-08-06 2022-06-15 Biocryst Pharm Inc SYNTHESIS OF A PLASMA KALLICEREIN INHIBITOR AT A PROCESS SCALE
AU2022249389A1 (en) 2021-04-02 2023-11-02 Dexcom, Inc. Personalized modeling of blood glucose concentration impacted by individualized sensor characteristics and individualized physiological characteristics
US20230113175A1 (en) 2021-10-08 2023-04-13 Medtronic Minimed, Inc. Immunosuppressant releasing coatings
US20240023849A1 (en) 2022-07-20 2024-01-25 Medtronic Minimed, Inc. Acrylate hydrogel membrane for dual function of diffusion limiting membrane as well as attenuation to the foreign body response

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4484987A (en) * 1983-05-19 1984-11-27 The Regents Of The University Of California Method and membrane applicable to implantable sensor
CA1283872C (en) 1985-02-19 1991-05-07 Steven D. Aust Process for the degradation of environmentally persistent organic compounds
US4890620A (en) * 1985-09-20 1990-01-02 The Regents Of The University Of California Two-dimensional diffusion glucose substrate sensing electrode
US4909908A (en) * 1986-04-24 1990-03-20 Pepi Ross Electrochemical cncentration detector method
US5214119A (en) * 1986-06-20 1993-05-25 Minnesota Mining And Manufacturing Company Block copolymer, method of making the same, dimaine precursors of the same, method of making such diamines and end products comprising the block copolymer
GB2194843A (en) 1986-09-08 1988-03-16 Cambridge Life Sciences Enzyme electrode membrane and method of making same
US4759828A (en) * 1987-04-09 1988-07-26 Nova Biomedical Corporation Glucose electrode and method of determining glucose
US4816130A (en) * 1987-07-02 1989-03-28 Becton, Dickinson And Company Blood electrolyte sensors including crosslinked polyetherurethane membranes
US5128408A (en) * 1987-11-16 1992-07-07 Toyo Boseki Kabushiki Kaisha Gas-permeable material with excellent compatibility with blood
US5000955A (en) * 1988-07-29 1991-03-19 Tyndale Plains-Hunter Ltd. Thermally reversible polyurethane hydrogels and cosmetic, biological and medical uses
JPH02298855A (en) 1989-03-20 1990-12-11 Assoc Univ Inc Electrochemical biosensor using immobilized enzyme and redox polymer
US4990357A (en) * 1989-05-04 1991-02-05 Becton, Dickinson And Company Elastomeric segmented hydrophilic polyetherurethane based lubricious coatings
GB8918589D0 (en) 1989-08-15 1989-09-27 Graham Neil B Polymeric compositions
US5108819A (en) * 1990-02-14 1992-04-28 Eli Lilly And Company Thin film electrical component
US5165407A (en) * 1990-04-19 1992-11-24 The University Of Kansas Implantable glucose sensor
US5334691A (en) * 1990-07-24 1994-08-02 Tyndale Plains-Hunter Ltd. Hydrophilic polyurethanes of improved strength
US5160790A (en) 1990-11-01 1992-11-03 C. R. Bard, Inc. Lubricious hydrogel coatings
EP0643833A1 (en) 1991-06-04 1995-03-22 FISONS plc Analytical device
US5322063A (en) 1991-10-04 1994-06-21 Eli Lilly And Company Hydrophilic polyurethane membranes for electrochemical glucose sensors
US5238732A (en) * 1992-07-16 1993-08-24 Surface Coatings, Inc. Waterproof breathable polyurethane membranes and porous substrates protected therewith
US5239037A (en) * 1992-07-16 1993-08-24 Surface Coatings, Inc. Waterproof breathable polyurethane membranes and porous substrates protected therewith
US5208313A (en) * 1992-07-16 1993-05-04 Surface Coatings, Inc. Waterproof breathable polyurethane membranes and porous substrates protected therewith
CA2121660A1 (en) 1993-05-10 1994-11-11 Gregory J. Mann Biostable polyurethane and medical article therefrom
US5484818A (en) * 1993-07-22 1996-01-16 Imperial Chemical Industries Plc Organic aerogels
AU1060495A (en) 1993-12-01 1995-06-19 Universite Du Quebec A Montreal Albumin based hydrogel
US5788687A (en) * 1994-02-01 1998-08-04 Caphco, Inc Compositions and devices for controlled release of active ingredients
US5391250A (en) * 1994-03-15 1995-02-21 Minimed Inc. Method of fabricating thin film sensors
US5390671A (en) * 1994-03-15 1995-02-21 Minimed Inc. Transcutaneous sensor insertion set
US5674275A (en) * 1994-04-06 1997-10-07 Graphic Controls Corporation Polyacrylate and polymethacrylate ester based hydrogel adhesives
US5614586A (en) * 1994-04-06 1997-03-25 Graphic Controls Corporation Polyacrylate and Polymethacrylate ester based hydrogel adhesives
EP0755244A1 (en) * 1994-04-13 1997-01-29 Novartis AG Temporally controlled drug delivery systems
US6322815B1 (en) * 1994-07-22 2001-11-27 W. Mark Saltzman Multipart drug delivery system
WO1996015443A1 (en) 1994-11-14 1996-05-23 Chiron Diagnostics Corporation_ RANDOMLY SEGMENTED THERMOPLASTIC POLYURETHANES AS MATRIX FOR ELECTROCHEMICAL ANALYSIS OF Ca++ IONS
US6017577A (en) * 1995-02-01 2000-01-25 Schneider (Usa) Inc. Slippery, tenaciously adhering hydrophilic polyurethane hydrogel coatings, coated polymer substrate materials, and coated medical devices
US6231600B1 (en) * 1995-02-22 2001-05-15 Scimed Life Systems, Inc. Stents with hybrid coating for medical devices
US5786439A (en) * 1996-10-24 1998-07-28 Minimed Inc. Hydrophilic, swellable coatings for biosensors
US5882494A (en) * 1995-03-27 1999-03-16 Minimed, Inc. Polyurethane/polyurea compositions containing silicone for biosensor membranes
US5837313A (en) * 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
GB9511233D0 (en) * 1995-06-03 1995-07-26 Watson Jermey Lubricious coatings
US6273913B1 (en) * 1997-04-18 2001-08-14 Cordis Corporation Modified stent useful for delivery of drugs along stent strut
US6221425B1 (en) * 1998-01-30 2001-04-24 Advanced Cardiovascular Systems, Inc. Lubricious hydrophilic coating for an intracorporeal medical device
US6300458B1 (en) * 1998-09-02 2001-10-09 Edwin J. Vandenberg High molecular weight polymers and copolymers of BHMDO for biomedical application
US6287588B1 (en) * 1999-04-29 2001-09-11 Macromed, Inc. Agent delivering system comprised of microparticle and biodegradable gel with an improved releasing profile and methods of use thereof
US6200599B1 (en) * 1999-10-07 2001-03-13 The Regents Of The University Of California Ortho ester lipids

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