WO2004042360A2 - Deuterated glucose or fat tolerance tests for high-throughput measurement of the metabolism of sugars or fatty acids in the body - Google Patents
Deuterated glucose or fat tolerance tests for high-throughput measurement of the metabolism of sugars or fatty acids in the body Download PDFInfo
- Publication number
- WO2004042360A2 WO2004042360A2 PCT/US2003/035107 US0335107W WO2004042360A2 WO 2004042360 A2 WO2004042360 A2 WO 2004042360A2 US 0335107 W US0335107 W US 0335107W WO 2004042360 A2 WO2004042360 A2 WO 2004042360A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- glucose
- labeled
- metabolism
- individual
- fatty acids
- Prior art date
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Emergency Medicine (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Child & Adolescent Psychology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03768624A EP1558293A4 (en) | 2002-11-04 | 2003-11-04 | Deuterated glucose or fat tolerance tests for high-throughput measurement of the metabolism of sugars or fatty acids in the body |
AU2003291731A AU2003291731B2 (en) | 2002-11-04 | 2003-11-04 | Deuterated glucose or fat tolerance tests for high-throughput measurement of the metabolism of sugars or fatty acids in the body |
JP2004550465A JP4611025B2 (en) | 2002-11-04 | 2003-11-04 | Deuterated glucose or fat tolerance test for high-throughput measurement of glucose or fatty acid metabolism in the body |
CA2504313A CA2504313C (en) | 2002-11-04 | 2003-11-04 | Deuterated glucose or fat tolerance tests for high-throughput measurement of the metabolism of sugars or fatty acids in the body |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42396402P | 2002-11-04 | 2002-11-04 | |
US60/423,964 | 2002-11-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004042360A2 true WO2004042360A2 (en) | 2004-05-21 |
WO2004042360A3 WO2004042360A3 (en) | 2004-09-10 |
Family
ID=32312729
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/035107 WO2004042360A2 (en) | 2002-11-04 | 2003-11-04 | Deuterated glucose or fat tolerance tests for high-throughput measurement of the metabolism of sugars or fatty acids in the body |
Country Status (7)
Country | Link |
---|---|
US (2) | US7504233B2 (en) |
EP (1) | EP1558293A4 (en) |
JP (1) | JP4611025B2 (en) |
AU (1) | AU2003291731B2 (en) |
CA (1) | CA2504313C (en) |
SG (1) | SG152922A1 (en) |
WO (1) | WO2004042360A2 (en) |
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US7001587B2 (en) | 2001-10-24 | 2006-02-21 | The Regents Of The University Of California | Measurement of protein synthesis rates in humans and experimental systems by use of isotopically labeled water |
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US7255850B2 (en) | 2002-09-13 | 2007-08-14 | The Regents Of The University Of California | Methods for measuring rates of reserve cholesterol transport in vivo, as an index of anti-atherogenesis |
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US8005623B2 (en) | 2004-02-20 | 2011-08-23 | The Regents Of The University Of California | Molecular flux rates through critical pathways measured by stable isotope labeling in vivo, as biomarkers of drug action and disease activity |
US8481478B2 (en) | 2002-07-30 | 2013-07-09 | The Regents Of The University Of California | Method for automated, large-scale measurement of the molecular flux rates of the proteome or the organeome using mass spectrometry |
US8663602B2 (en) | 2003-11-25 | 2014-03-04 | The Regents Of The University Of California | Method for high-throughput screening of compounds and combinations of compounds for discovery and quantification of actions, particularly unanticipated therapeutic or toxic actions, in biological systems |
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US10386371B2 (en) | 2011-09-08 | 2019-08-20 | The Regents Of The University Of California | Metabolic flux measurement, imaging and microscopy |
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US7449171B2 (en) * | 2002-02-12 | 2008-11-11 | The Regents Of The University Of California | Measurement of biosynthesis and breakdown rates of biological molecules that are inaccessible or not easily accessible to direct sampling, non-invasively, by label incorporation into metabolic derivatives and catabolic products |
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US20070248540A1 (en) * | 2002-09-16 | 2007-10-25 | The Regents Of The University Of California | Biochemical methods for measuring metabolic fitness of tissues or whole organisms |
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US8460243B2 (en) | 2003-06-10 | 2013-06-11 | Abbott Diabetes Care Inc. | Glucose measuring module and insulin pump combination |
US7722536B2 (en) | 2003-07-15 | 2010-05-25 | Abbott Diabetes Care Inc. | Glucose measuring device integrated into a holster for a personal area network device |
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2003
- 2003-11-04 AU AU2003291731A patent/AU2003291731B2/en not_active Ceased
- 2003-11-04 EP EP03768624A patent/EP1558293A4/en not_active Withdrawn
- 2003-11-04 US US10/701,990 patent/US7504233B2/en active Active
- 2003-11-04 JP JP2004550465A patent/JP4611025B2/en not_active Expired - Fee Related
- 2003-11-04 WO PCT/US2003/035107 patent/WO2004042360A2/en active Application Filing
- 2003-11-04 SG SG200705275-6A patent/SG152922A1/en unknown
- 2003-11-04 CA CA2504313A patent/CA2504313C/en not_active Expired - Fee Related
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2009
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Also Published As
Publication number | Publication date |
---|---|
US7910323B2 (en) | 2011-03-22 |
JP4611025B2 (en) | 2011-01-12 |
EP1558293A4 (en) | 2006-10-25 |
AU2003291731B2 (en) | 2009-09-10 |
US20100041082A1 (en) | 2010-02-18 |
AU2003291731A1 (en) | 2004-06-07 |
SG152922A1 (en) | 2009-06-29 |
CA2504313A1 (en) | 2004-05-21 |
WO2004042360A3 (en) | 2004-09-10 |
EP1558293A2 (en) | 2005-08-03 |
CA2504313C (en) | 2012-01-17 |
US20040115131A1 (en) | 2004-06-17 |
US7504233B2 (en) | 2009-03-17 |
JP2006505777A (en) | 2006-02-16 |
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