WO2004053483A3 - Multi-analyte reference solutions - Google Patents

Multi-analyte reference solutions Download PDF

Info

Publication number
WO2004053483A3
WO2004053483A3 PCT/US2003/039411 US0339411W WO2004053483A3 WO 2004053483 A3 WO2004053483 A3 WO 2004053483A3 US 0339411 W US0339411 W US 0339411W WO 2004053483 A3 WO2004053483 A3 WO 2004053483A3
Authority
WO
WIPO (PCT)
Prior art keywords
reference solution
conductivity
levels
biological samples
glycol
Prior art date
Application number
PCT/US2003/039411
Other languages
French (fr)
Other versions
WO2004053483A2 (en
Inventor
Dennis Robert Conlon
Sohrab Mansouri
Giannantonio Vago
Original Assignee
Instrumentation Lab Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instrumentation Lab Co filed Critical Instrumentation Lab Co
Priority to AU2003296492A priority Critical patent/AU2003296492A1/en
Publication of WO2004053483A2 publication Critical patent/WO2004053483A2/en
Publication of WO2004053483A3 publication Critical patent/WO2004053483A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4915—Blood using flow cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/492—Determining multiple analytes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/102499—Blood gas standard or control
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/104998—Glucose, ketone, nitrate standard or control
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/106664—Blood serum or blood plasma standard or control
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331—Preservative, buffer, anticoagulant or diluent

Abstract

The present invention provides a reference solution for use in instruments that determine hematocrit levels in biological samples by measuring the resistance and/or conductivity of the biological samples. A reference solution according to the invention achieves conductivities representative of known hematocrit levels in blood, while maintaining tolerable levels of interference with the measurement of other analytes in the reference solution. The reference solution comprises at least two compounds selected from the group consisting of a water soluble polymer (e.g. polyethylene glycol), a glycol (e.g. ethylene glycol, and a polysaccharide (e.g. dextran) wherein the conductivity of the solution corresponds to a known hematocrit level.
PCT/US2003/039411 2002-12-11 2003-12-11 Multi-analyte reference solutions WO2004053483A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003296492A AU2003296492A1 (en) 2002-12-11 2003-12-11 Multi-analyte reference solutions

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43237302P 2002-12-11 2002-12-11
US60/432,373 2002-12-11

Publications (2)

Publication Number Publication Date
WO2004053483A2 WO2004053483A2 (en) 2004-06-24
WO2004053483A3 true WO2004053483A3 (en) 2004-09-16

Family

ID=32507915

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/039411 WO2004053483A2 (en) 2002-12-11 2003-12-11 Multi-analyte reference solutions

Country Status (3)

Country Link
US (2) US7422903B2 (en)
AU (1) AU2003296492A1 (en)
WO (1) WO2004053483A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071384B2 (en) * 1997-12-22 2011-12-06 Roche Diagnostics Operations, Inc. Control and calibration solutions and methods for their use
ATE522806T1 (en) * 2002-07-26 2011-09-15 Instrumentation Lab Co METHOD FOR REDUCING THE RATE OF OXYGEN LOSS FROM AQUEOUS SOLUTIONS
WO2004053483A2 (en) * 2002-12-11 2004-06-24 Instrumentation Laboratory Company Multi-analyte reference solutions
US7723099B2 (en) * 2003-09-10 2010-05-25 Abbott Point Of Care Inc. Immunoassay device with immuno-reference electrode
US7356366B2 (en) * 2004-08-02 2008-04-08 Cardiac Pacemakers, Inc. Device for monitoring fluid status
ES2552083T3 (en) * 2005-04-08 2015-11-25 Bayer Healthcare Llc Oxidizable species as internal reference in control solutions for biosensors
US20080149482A1 (en) * 2006-12-21 2008-06-26 Healthwatchsystems, Inc. Reference electrode and reference solutions for use therein
PL2185939T3 (en) 2007-09-01 2012-05-31 Life Assays Ab Disposable analytical microprocessor device
TWI391655B (en) * 2009-04-01 2013-04-01 Apex Biotechnology Corp Control solution for determining performance of electrochemical sensing system and method for the same
CN101852759A (en) * 2009-04-01 2010-10-06 五鼎生物技术股份有限公司 Contrasting fluid deciding effectiveness of electrochemical sensing system and method thereof
US8438898B2 (en) * 2009-07-01 2013-05-14 Edwards Lifesciences Corporation Calibrant infusion fluid source preparation
US20110129574A1 (en) * 2009-11-30 2011-06-02 Pathak Chandrashekhar P Methods and compositions for filling fleshy fruits and vegetables
US9625465B2 (en) 2012-05-15 2017-04-18 Defined Diagnostics, Llc Clinical diagnostic systems
US9075042B2 (en) 2012-05-15 2015-07-07 Wellstat Diagnostics, Llc Diagnostic systems and cartridges
US9213043B2 (en) 2012-05-15 2015-12-15 Wellstat Diagnostics, Llc Clinical diagnostic system including instrument and cartridge
EP3373004B1 (en) * 2017-03-07 2019-12-11 F. Hoffmann-La Roche AG Method of determining an analyte concentration
CN114846332A (en) * 2019-10-25 2022-08-02 仪器实验室公司 Biocide compositions compatible with enzyme biosensors and methods of use thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4686479A (en) * 1985-07-22 1987-08-11 Young Chung C Apparatus and control kit for analyzing blood sample values including hematocrit
US4734184A (en) * 1985-08-29 1988-03-29 Diamond Sensor Systems, Inc. Self-activating hydratable solid-state electrode apparatus
WO1994006019A1 (en) * 1992-08-28 1994-03-17 Via Medical Corporation Calibration solutions useful for analyses of biological fluids and methods employing same
WO2001042473A2 (en) * 1999-12-10 2001-06-14 Instrumentation Laboratory Company Device and method for accelerated hydration of dry chemical sensors

Family Cites Families (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3796634A (en) 1970-03-19 1974-03-12 Us Health Education & Welfare Insolubilized biologically active enzymes
US3658478A (en) 1970-04-07 1972-04-25 Instrumentation Labor Inc Fluid analyzing apparatus
US3723281A (en) 1972-01-31 1973-03-27 Corning Glass Works Bicarbonate ion sensitive electrode
US3915829A (en) 1972-10-10 1975-10-28 Instrumentation Labor Inc Electrochemical structure
US3920580A (en) * 1973-07-12 1975-11-18 Miles Lab Liquid control solution
US3977995A (en) 1974-10-17 1976-08-31 Baxter Laboratories, Inc. Calibrating fluid for blood cell counting and hemoglobin determination
DE2612726C3 (en) 1976-03-25 1979-03-15 Boehringer Mannheim Gmbh, 6800 Mannheim Stabilized urease
US4214968A (en) 1978-04-05 1980-07-29 Eastman Kodak Company Ion-selective electrode
US4219440A (en) 1979-06-06 1980-08-26 Coulter Electronics, Inc. Multiple analysis hematology reference control reagent and method of making the same
CA1112474A (en) 1978-09-18 1981-11-17 Guy Belanger Apparatus for the detection and the measurement of hydrogen concentration in a liquid
US4179349A (en) 1978-09-26 1979-12-18 The United States Of America As Represented By The United States Department Of Energy Portable probe to measure sensitization of stainless steel
US4361539A (en) 1980-05-05 1982-11-30 Instrumentation Laboratory Inc. Analysis system
JPS57118152A (en) 1981-01-14 1982-07-22 Matsushita Electric Ind Co Ltd Enzyme electrode
US4401548A (en) 1981-02-12 1983-08-30 Corning Glass Works Reference electrode with internal diffusion barrier
US4355105A (en) 1981-03-30 1982-10-19 Miles Laboratories, Inc. Glutaraldehyde/polyethylenimine immobilization of whole microbial cells
EP0074498B1 (en) 1981-09-04 1985-12-04 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Method and apparatus for the calibration of sensors
US4390627A (en) 1981-10-26 1983-06-28 Miles Laboratories, Inc. Immobilization of the sucrose mutase in whole cells of protaminobacter rubrum
DK149830C (en) 1982-05-17 1987-02-16 Radiometer As METHOD OF DETERMINING THE CONCENTRATION OF AN ION IN A SAMPLE OF BLOOD OR BLOOD FLUID
DE3223885A1 (en) 1982-06-26 1983-12-29 Basf Ag, 6700 Ludwigshafen MACROPOROISE, HYDROPHILE CARRIER FOR ENZYME
CA1223638A (en) 1983-05-05 1987-06-30 Graham Davis Assay systems utilising more than one enzyme
CA1210717A (en) 1983-08-10 1986-09-02 Oreste J. Lantero, Jr. Immobilization of biocatalysts
US4760024A (en) 1983-08-10 1988-07-26 Miles Inc. Immobilization of enzymes
EP0138150A3 (en) 1983-10-05 1988-06-01 E.I. Du Pont De Nemours And Company Diagnostic electrode membranes utilizing specific enzyme/ionophore pairs
JPS60155959A (en) 1984-01-25 1985-08-16 Matsushita Electric Works Ltd Measurement using biosensor
US4654127A (en) 1984-04-11 1987-03-31 Sentech Medical Corporation Self-calibrating single-use sensing device for clinical chemistry and method of use
AT380741B (en) 1985-01-31 1986-06-25 Avl Ges F R Verbrennungskraftm ION-SENSITIVE MEMBRANE ELECTRODE
US4755461A (en) 1986-04-17 1988-07-05 Bio/Data Corporation Tableted blood plasma microconcentrated thromboplastin coagulation reagent
US4713165A (en) 1986-07-02 1987-12-15 Ilex Corporation Sensor having ion-selective electrodes
GB2194843A (en) 1986-09-08 1988-03-16 Cambridge Life Sciences Enzyme electrode membrane and method of making same
US4810351A (en) 1986-09-18 1989-03-07 Technicon Instruments Corporation Carbonate selective membrane and electrode
US4818365A (en) 1986-10-14 1989-04-04 Monsanto Company Solid state indicator electrode and method of making same
US4908117A (en) 1986-11-13 1990-03-13 Monsanto Company Solid state reference electrode
US4818361A (en) 1986-12-10 1989-04-04 Diamond Sensor Systems Combined pH and dissolved carbon dioxide gas sensor
US4871439A (en) 1987-02-05 1989-10-03 Steven Enzer Disposable self-calibratable electrode package
US4975647A (en) 1987-06-01 1990-12-04 Nova Biomedical Corporation Controlling machine operation with respect to consumable accessory units
US5286364A (en) 1987-06-08 1994-02-15 Rutgers University Surface-modified electochemical biosensor
US5540828A (en) 1987-06-08 1996-07-30 Yacynych; Alexander Method for making electrochemical sensors and biosensors having a polymer modified surface
JPS6423155A (en) 1987-07-17 1989-01-25 Daikin Ind Ltd Electrode refreshing device for biosensor
JPS6423151A (en) 1987-07-20 1989-01-25 Hitachi Ltd Chlorine ion selective electrode
JPS6428555A (en) 1987-07-24 1989-01-31 Terumo Corp Enzyme sensor
US5013666A (en) 1988-06-15 1991-05-07 Bionostics, Incorporated Control for blood gas/calcium analysis instrumentation
US4945062A (en) 1988-06-15 1990-07-31 Bionostics Incorporated Control for blood gas/calcium analysis instrumentation
US5061631A (en) 1988-10-14 1991-10-29 Fisher Scientific Company Method, apparatus and solution for calibration of partial pressure value
US5070023A (en) 1988-10-14 1991-12-03 Fisher Scientific Company Aqueous ferrioxalate compositions useful as calibrants
US4973394A (en) 1988-09-02 1990-11-27 Sri International Immobilized valinomycin molecule for K+ sensor
JPH0287055A (en) 1988-09-24 1990-03-27 Terumo Corp Calibrating solution of sensor and calibrating method therefor
US5212050A (en) 1988-11-14 1993-05-18 Mier Randall M Method of forming a permselective layer
US5200051A (en) 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
US5130010A (en) 1989-03-13 1992-07-14 Beckman Instruments, Inc. Salt bridge for analytical chemistry system
US5558985A (en) 1989-03-27 1996-09-24 Bionostics Incorporated Stable hemoglobin reference solution
US5352349A (en) 1989-08-30 1994-10-04 Daikin Industries, Ltd. Method for reviving an electrode of a biosensor
US5067093A (en) 1990-01-24 1991-11-19 Eastman Kodak Company Reference reading in an analyzer
US5103179A (en) 1990-03-05 1992-04-07 Industrial Chemical Measurement, Inc. Water analyzer with multiple electrodes
US5162077A (en) 1990-12-10 1992-11-10 Bryan Avron I Device for in situ cleaning a fouled sensor membrane of deposits
IE904444A1 (en) 1990-12-10 1992-06-17 Stephen J Harris Ion-selective electrodes
US5262305A (en) 1991-03-04 1993-11-16 E. Heller & Company Interferant eliminating biosensors
US5849517A (en) * 1991-05-08 1998-12-15 Streck Laboratories, Inc. Method and composition for preserving antigens and nucleic acids and process for utilizing cytological material produced by same
EP0520443B1 (en) 1991-06-26 1997-01-08 Ppg Industries, Inc. Electrochemical sensor assembly
US5342498A (en) 1991-06-26 1994-08-30 Graves Jeffrey A Electronic wiring substrate
US5370783A (en) 1991-08-01 1994-12-06 Corrpro Companies, Inc. Electrode
US5776563A (en) * 1991-08-19 1998-07-07 Abaxis, Inc. Dried chemical compositions
WO1993013408A1 (en) 1991-12-31 1993-07-08 Abbott Laboratories Composite membrane
WO1993021533A1 (en) 1992-04-20 1993-10-28 Mallinckrodt Sensor Systems, Inc. Calibration reagent having a stabilized concentration of dissolved gas
US5405510A (en) 1992-05-18 1995-04-11 Ppg Industries, Inc. Portable analyte measuring system for multiple fluid samples
ZA938555B (en) 1992-11-23 1994-08-02 Lilly Co Eli Technique to improve the performance of electrochemical sensors
US5321345A (en) * 1992-12-11 1994-06-14 George Lambros Moisture activated sensor system
WO1994019683A1 (en) 1993-02-25 1994-09-01 Diametrics Medical, Inc. Disposable electrochemical measurement cartridge
WO1994019684A1 (en) 1993-02-25 1994-09-01 Diametrics Medical, Inc. Portable immediate response medical analyzer
US5403451A (en) 1993-03-05 1995-04-04 Riviello; John M. Method and apparatus for pulsed electrochemical detection using polymer electroactive electrodes
US5387329A (en) 1993-04-09 1995-02-07 Ciba Corning Diagnostics Corp. Extended use planar sensors
ATE256179T1 (en) 1993-09-01 2003-12-15 Genencor Int METHOD FOR PRODUCING IMMOBILIZED ENZYME CONJUGATES AND IMMOBILIZED ENZYME CONJUGATES SO OBTAINED
GB9320782D0 (en) 1993-10-08 1993-12-01 Univ Leeds Innovations Ltd Stabilising of proteins on solution
US5522978A (en) 1993-11-18 1996-06-04 E. I. Du Pont De Nemours And Company Monensin amides for sodium-selective electrodes
US5705482A (en) 1995-01-13 1998-01-06 Novo Nordisk A/S Pharmaceutical formulation
US5798030A (en) 1995-05-17 1998-08-25 Australian Membrane And Biotechnology Research Institute Biosensor membranes
US5972199A (en) 1995-10-11 1999-10-26 E. Heller & Company Electrochemical analyte sensors using thermostable peroxidase
EP0771867A3 (en) 1995-10-30 1998-09-02 Ciba-Geigy Japan Limited Enzyme electrode
US5780302A (en) 1995-11-02 1998-07-14 Chiron Diagnostics Corporation Method of packaging oxygen reference solution using flexile package with inside valve
US6136607A (en) 1995-11-02 2000-10-24 Bayer Corporation Multi-analyte reference solutions with stable pO2 in zero headspace containers
AU6084496A (en) 1995-11-03 1997-05-08 Ciba Corning Diagnostics Corp. Reference electrode assembly
US5605837A (en) 1996-02-14 1997-02-25 Lifescan, Inc. Control solution for a blood glucose monitor
US5653862A (en) 1996-04-15 1997-08-05 Dade Chemistry Systems Inc. Biochemical sensor device and method
DE69735127T2 (en) 1996-11-14 2006-08-31 Radiometer Medical Aps ENZYME SENSOR
US6103505A (en) 1996-12-09 2000-08-15 Novo Nordisk A/S Method for reducing phosphorus content of edible oils
EP0872726A1 (en) 1997-04-15 1998-10-21 INSTRUMENTATION LABORATORY S.p.A. Method for calibrating an instrument for measuring electrolytes and metabolites by analysis of blood gases
AT404992B (en) 1997-04-17 1999-04-26 Avl List Gmbh SENSOR FOR DETERMINING AN ENZYME SUBSTRATE
WO2000010674A1 (en) * 1997-08-19 2000-03-02 Arnon Chait Method for evaluation of the ratio of amounts of biomolecules or their sub-populations in a mixture
US5906921A (en) 1997-09-29 1999-05-25 Matsushita Electric Industrial Co., Ltd. Biosensor and method for quantitative measurement of a substrate using the same
AU1628699A (en) 1997-12-05 1999-06-28 Medical College Of Georgia Research Institute, Inc. High-affinity tryptophan transporter
US6030827A (en) 1998-01-23 2000-02-29 I-Stat Corporation Microfabricated aperture-based sensor
US6174728B1 (en) 1998-04-03 2001-01-16 Avl Medical Instruments Ag Control or calibration standard for use with instruments for optical measurement of hemoglobin concentration in blood samples
GB9808517D0 (en) 1998-04-23 1998-06-17 Aea Technology Plc Electrical sensor
US6123820A (en) 1998-06-05 2000-09-26 Grupo Ch-Werfen, S.A. Sensor cartridges
CA2335747A1 (en) * 1998-06-30 2000-01-06 Lamina, Inc. Cytological and histological fixative composition and methods of use
KR20000053521A (en) 1999-01-20 2000-08-25 고사이 아끼오 Metal-corrosion inhibitor and cleaning liquid
SE512534C2 (en) 1999-04-22 2000-03-27 Btg Kaelle Inventing Ab Method for cleaning electrodes in measuring equipment
KR100360774B1 (en) 1999-12-27 2002-11-13 한국전자통신연구원 Enzyme electrode sensor and manufacturing method thereof
US6337189B1 (en) * 2000-02-08 2002-01-08 Streck Laboratories, Inc. Fixative system, method and composition for biological testing
US6652720B1 (en) 2001-05-31 2003-11-25 Instrumentation Laboratory Company Analytical instruments, biosensors and methods thereof
US6872297B2 (en) 2001-05-31 2005-03-29 Instrumentation Laboratory Company Analytical instruments, biosensors and methods thereof
US6960466B2 (en) 2001-05-31 2005-11-01 Instrumentation Laboratory Company Composite membrane containing a cross-linked enzyme matrix for a biosensor
US7022219B2 (en) 2001-08-22 2006-04-04 Instrumentation Laboratory Company Automated system for continuously and automatically calibrating electrochemical sensors
WO2004053483A2 (en) * 2002-12-11 2004-06-24 Instrumentation Laboratory Company Multi-analyte reference solutions
US20040154933A1 (en) 2003-02-11 2004-08-12 Instrumentation Laboratory Company Polymeric membranes for use in electrochemical sensors

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4686479A (en) * 1985-07-22 1987-08-11 Young Chung C Apparatus and control kit for analyzing blood sample values including hematocrit
US4734184A (en) * 1985-08-29 1988-03-29 Diamond Sensor Systems, Inc. Self-activating hydratable solid-state electrode apparatus
WO1994006019A1 (en) * 1992-08-28 1994-03-17 Via Medical Corporation Calibration solutions useful for analyses of biological fluids and methods employing same
WO2001042473A2 (en) * 1999-12-10 2001-06-14 Instrumentation Laboratory Company Device and method for accelerated hydration of dry chemical sensors

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
OHBOSHI S ET AL: "Usefulness of polyethylene glycol for cryopreservation by vitrification of in vitro-derived bovine blastocysts", July 1997, ANIMAL REPRODUCTION SCIENCE, VOL. 48, NR. 1, PAGE(S) 27-36, ISSN: 0378-4320, XP002283341 *
VARLAN A R ET AL: "New design technique for planar conductometric haematocrit sensors", SENSORS AND ACTUATORS B, ELSEVIER SEQUOIA S.A., LAUSANNE, CH, vol. 34, no. 1-3, 1 August 1996 (1996-08-01), pages 258 - 264, XP004077988, ISSN: 0925-4005 *
WANG W B ET AL: "Cryopreservation of Musca domestica (Diptera: Muscidae) embryos", CRYOBIOLOGY (USA), CRYOBIOLOGY, SEPT. 2000, ACADEMIC PRESS, USA, vol. 41, no. 2, September 2000 (2000-09-01), pages 153 - 166, XP002283340, ISSN: 0011-2240 *

Also Published As

Publication number Publication date
US20090215181A1 (en) 2009-08-27
WO2004053483A2 (en) 2004-06-24
US7732210B2 (en) 2010-06-08
US7422903B2 (en) 2008-09-09
US20040209371A1 (en) 2004-10-21
AU2003296492A1 (en) 2004-06-30

Similar Documents

Publication Publication Date Title
WO2004053483A3 (en) Multi-analyte reference solutions
WO2003040728A3 (en) Method and apparatus for the determination of glucose
BR0112871A (en) Analyte detection for aqueous environments
WO2007121111A3 (en) System and methods for providing corrected analyte concentration measurements
WO2002077641A3 (en) Reference electrode
TW200608019A (en) Methods for performing hematocrit adjustment in glucose assays and devices for same
WO2003030731A3 (en) Method and apparatus for improving clinical accuracy of analyte measurements
WO2008078781A1 (en) Hemoglobin measurement method and electrophoresis apparatus
WO2004004647A3 (en) Nanoparticle polyanion conjugates and methods of use thereof in detecting analytes
TWI256975B (en) Compositions containing a urea derivative dye for detecting an analyte and methods for using the same
EP1447665A3 (en) Method for reducing effect of hematocrit on measurement of an analyte in whole blood, and test kit and test article useful in the method
CA2568824A1 (en) Glucose biosensor and method
WO2011079938A3 (en) System and method for determining the concentration of an analyte in a sample fluid
WO2002027326A3 (en) Method and kit for the transderaml determination of analyte concentration in blood
WO2002055008A3 (en) Meter strip dispenser assembly
MX2007001770A (en) Analyte test system for determining the concentration of an analyte in a physiological or aqueous fluid.
WO2008007359A3 (en) Rapid diagnostic devices based on molecular imprinted polymers
WO2007035864A3 (en) Electrophoresis standards, methods and kits
EP1445329A3 (en) Method and test strip for determining glucose in blood
Thavarungkul et al. Continuous monitoring of urea in blood during dialysis
CN109916895A (en) A kind of dry chemistry reagent piece and preparation method thereof quantitative determining creatine concentration
AU615853B2 (en) Process and reagent for the determination of the ionic strength or of the specific weight of aqueous liquids
WO2005086594A3 (en) Measurement value lowering inhibitor for immunoassay method and immunoassay method using the same
TW200739073A (en) Test sensor reagent having cellulose polymers
WO2004016160A3 (en) Redox polymer nanoparticles

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP