WO2004112890A3 - Method for intraoperative radiation treatment of breast cancer - Google Patents

Method for intraoperative radiation treatment of breast cancer Download PDF

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Publication number
WO2004112890A3
WO2004112890A3 PCT/US2004/019621 US2004019621W WO2004112890A3 WO 2004112890 A3 WO2004112890 A3 WO 2004112890A3 US 2004019621 W US2004019621 W US 2004019621W WO 2004112890 A3 WO2004112890 A3 WO 2004112890A3
Authority
WO
WIPO (PCT)
Prior art keywords
radiation
cavity
breast cancer
excision
radiation treatment
Prior art date
Application number
PCT/US2004/019621
Other languages
French (fr)
Other versions
WO2004112890A2 (en
WO2004112890A9 (en
Inventor
Paul A Lovoi
Original Assignee
Xoft Microtube Inc
Paul A Lovoi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xoft Microtube Inc, Paul A Lovoi filed Critical Xoft Microtube Inc
Priority to JP2006517442A priority Critical patent/JP2007526010A/en
Priority to EP04755661A priority patent/EP1658110A4/en
Publication of WO2004112890A2 publication Critical patent/WO2004112890A2/en
Publication of WO2004112890A9 publication Critical patent/WO2004112890A9/en
Publication of WO2004112890A3 publication Critical patent/WO2004112890A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1014—Intracavitary radiation therapy
    • A61N5/1015—Treatment of resected cavities created by surgery, e.g. lumpectomy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1014—Intracavitary radiation therapy
    • A61N2005/1018—Intracavitary radiation therapy with multiple channels for guiding radioactive sources
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/103—Treatment planning systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods

Abstract

Breast cancer patients are treated intraoperatively with radiation shortly after excision of a tumor. Pathology of the tissue is determined with a nearly instantaneous method, further excision is performed if needed, and the patient, still anesthetized and preferably unmoved, is then treated with radiation therapy. In a preferred embodiment an applicator is inserted into the excision cavity, the cavity is three­dimensionally mapped using radiation sources and a sensor, a radiation treatment plan is developed using a radiation prescription and the determined shape and location of the cavity, and the treatment plan is executed, all while the patient remains under anesthesia.
PCT/US2004/019621 2003-06-18 2004-06-18 Method for intraoperative radiation treatment of breast cancer WO2004112890A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2006517442A JP2007526010A (en) 2003-06-18 2004-06-18 Radiotherapy during surgery for breast cancer
EP04755661A EP1658110A4 (en) 2003-06-18 2004-06-18 Method for intraoperative radiation treatment of breast cancer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/464,140 US7322929B2 (en) 2003-06-18 2003-06-18 Method for radiation treatment
US10/464,140 2003-06-18

Publications (3)

Publication Number Publication Date
WO2004112890A2 WO2004112890A2 (en) 2004-12-29
WO2004112890A9 WO2004112890A9 (en) 2005-02-03
WO2004112890A3 true WO2004112890A3 (en) 2006-09-14

Family

ID=33517226

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/019621 WO2004112890A2 (en) 2003-06-18 2004-06-18 Method for intraoperative radiation treatment of breast cancer

Country Status (5)

Country Link
US (1) US7322929B2 (en)
EP (1) EP1658110A4 (en)
JP (1) JP2007526010A (en)
KR (1) KR100990553B1 (en)
WO (1) WO2004112890A2 (en)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030038837A (en) * 2001-11-06 2003-05-17 피티플러스(주) A Crystalline Silicon Thin Film Transistor Panel for LCD and Fabrication Method Thereof
EP2008690B1 (en) 2002-09-10 2013-11-06 Cianna Medical, Inc. Brachytherapy apparatus
US8328710B2 (en) 2002-11-06 2012-12-11 Senorx, Inc. Temporary catheter for biopsy site tissue fixation
US6923754B2 (en) 2002-11-06 2005-08-02 Senorx, Inc. Vacuum device and method for treating tissue adjacent a body cavity
US7513861B2 (en) * 2003-06-18 2009-04-07 Xoft, Inc. Real time verification in radiation treatment
US8262555B2 (en) * 2003-06-18 2012-09-11 Xoft, Inc. Method for adaptive radiation treatment of breast tissue surrounding a cancer resection cavity of arbitrary shape
US7338430B2 (en) * 2003-06-18 2008-03-04 Xoft, Inc. Gynecological brachytherapy applicator and system
US20060173232A1 (en) * 2003-06-18 2006-08-03 Lovoi Paul A HDR adapter for electronic radiation source applicator
US7578780B2 (en) * 2003-06-18 2009-08-25 Xoft, Inc. Brachytherapy applicator for delivery and assessment of low-level ionizing radiation therapy and methods of use
DE102004008373B3 (en) * 2004-02-20 2005-09-29 Siemens Ag Apparatus for performing and monitoring endovascular brachytherapy
US7672705B2 (en) * 2004-07-19 2010-03-02 Resonant Medical, Inc. Weighted surface-to-surface mapping
US20060067467A1 (en) * 2004-09-28 2006-03-30 Minnesota Medical Physics Llc Apparatus and method for conformal radiation brachytherapy for breast and other tumors
US8989349B2 (en) 2004-09-30 2015-03-24 Accuray, Inc. Dynamic tracking of moving targets
US7662082B2 (en) 2004-11-05 2010-02-16 Theragenics Corporation Expandable brachytherapy device
CA2597711A1 (en) * 2005-02-15 2006-08-24 Advanced Radiation Therapy, Llc Peripheral brachytherapy of protruding conformable organs
US20100127181A1 (en) * 2005-09-22 2010-05-27 Lovoi Paul A Radiation sensor arrays for use with brachytherapy
US7372940B2 (en) * 2005-09-30 2008-05-13 Topel, Llc Radiation therapy system with risk mitigation
WO2007053823A2 (en) 2005-10-31 2007-05-10 Biolucent, Inc. Brachytherapy apparatus and methods of using same
US7887476B2 (en) 2005-11-10 2011-02-15 Cianna Medical, Inc. Helical brachytherapy apparatus and methods of using same
US7862496B2 (en) 2005-11-10 2011-01-04 Cianna Medical, Inc. Brachytherapy apparatus and methods for using them
US8273006B2 (en) * 2005-11-18 2012-09-25 Senorx, Inc. Tissue irradiation
US7465268B2 (en) * 2005-11-18 2008-12-16 Senorx, Inc. Methods for asymmetrical irradiation of a body cavity
US7413539B2 (en) * 2005-11-18 2008-08-19 Senorx, Inc. Treatment of a body cavity
EP2029230A2 (en) 2006-06-02 2009-03-04 Cianna Medical, Inc. Expandable brachytherapy apparatus
US20080021300A1 (en) * 2006-06-29 2008-01-24 Allison John W Four-dimensional target modeling and radiation treatment
US20090080602A1 (en) * 2006-08-03 2009-03-26 Kenneth Brooks Dedicated breast radiation imaging/therapy system
US9451928B2 (en) 2006-09-13 2016-09-27 Elekta Ltd. Incorporating internal anatomy in clinical radiotherapy setups
US8734313B2 (en) * 2006-10-04 2014-05-27 Hampton University Accelerated partial breast irradiation with shielded brachytherapy applicator system and method of use
EP2380630B1 (en) 2006-10-08 2013-01-16 Cianna Medical, Inc. Expandable brachytherapy apparatus
US8287442B2 (en) 2007-03-12 2012-10-16 Senorx, Inc. Radiation catheter with multilayered balloon
US8740873B2 (en) * 2007-03-15 2014-06-03 Hologic, Inc. Soft body catheter with low friction lumen
US20080228023A1 (en) * 2007-03-15 2008-09-18 Senorx, Inc. Soft body catheter with low friction lumen
WO2009012577A1 (en) 2007-07-20 2009-01-29 Resonant Medical Inc. Methods and systems for compensating for changes in anatomy of radiotherapy patients
US10531858B2 (en) 2007-07-20 2020-01-14 Elekta, LTD Methods and systems for guiding the acquisition of ultrasound images
US8135198B2 (en) 2007-08-08 2012-03-13 Resonant Medical, Inc. Systems and methods for constructing images
US8467497B2 (en) * 2007-10-25 2013-06-18 Tomotherapy Incorporated System and method for motion adaptive optimization for radiation therapy delivery
WO2009055801A2 (en) * 2007-10-25 2009-04-30 Tomo Therapy Incorporated System and method for motion adaptive optimization for radiation therapy delivery
US8517907B2 (en) 2007-12-16 2013-08-27 Cianna Medical, Inc. Expandable brachytherapy apparatus and methods for using them
WO2009080085A1 (en) * 2007-12-21 2009-07-02 Elekta Ab (Publ) Apparatus for respiration state gated brachytherapy
US20090188098A1 (en) * 2008-01-24 2009-07-30 Senorx, Inc. Multimen brachytherapy balloon catheter
EP2269693A4 (en) * 2008-04-14 2015-07-08 Gmv Aerospace And Defence S A Planning system for intraoperative radiation therapy and method for carrying out said planning
US8189738B2 (en) 2008-06-02 2012-05-29 Elekta Ltd. Methods and systems for guiding clinical radiotherapy setups
US20100010287A1 (en) * 2008-07-09 2010-01-14 Senorx, Inc. Brachytherapy device with one or more toroidal balloons
US20110144476A1 (en) * 2008-08-18 2011-06-16 The Brigham And Women's Hospital, Inc. Integrated Surgical Sampling Probe
WO2010022103A1 (en) 2008-08-18 2010-02-25 Cianna Medical, Inc. Brachytherapy apparatus, systems, and methods for using them
US20100280409A1 (en) * 2008-09-30 2010-11-04 Mark Joseph L Real-time pathology
US8206315B2 (en) * 2008-09-30 2012-06-26 Suros Surgical Systems, Inc. Real-time pathology
US9579524B2 (en) 2009-02-11 2017-02-28 Hologic, Inc. Flexible multi-lumen brachytherapy device
US9248311B2 (en) 2009-02-11 2016-02-02 Hologic, Inc. System and method for modifying a flexibility of a brachythereapy catheter
US10207126B2 (en) 2009-05-11 2019-02-19 Cytyc Corporation Lumen visualization and identification system for multi-lumen balloon catheter
US8663210B2 (en) * 2009-05-13 2014-03-04 Novian Health, Inc. Methods and apparatus for performing interstitial laser therapy and interstitial brachytherapy
US10542962B2 (en) 2009-07-10 2020-01-28 Elekta, LTD Adaptive radiotherapy treatment using ultrasound
US9248316B2 (en) 2010-01-12 2016-02-02 Elekta Ltd. Feature tracking using ultrasound
US20110172526A1 (en) 2010-01-12 2011-07-14 Martin Lachaine Feature Tracking Using Ultrasound
CA2791990A1 (en) * 2010-03-01 2011-09-09 Intraop Medical Corporation Radiotherapy combined with hypoxic cell sensitizers
US8814775B2 (en) 2010-03-18 2014-08-26 Cianna Medical, Inc. Expandable brachytherapy apparatus and methods for using them
DE102010020352A1 (en) 2010-05-12 2011-11-17 Carl Zeiss Surgical Gmbh Method for generating and / or providing data for a tissue treatment
US9883919B2 (en) 2010-07-21 2018-02-06 Cianna Medical, Inc. Brachytherapy apparatus, systems, and methods for using them
US9352172B2 (en) 2010-09-30 2016-05-31 Hologic, Inc. Using a guide member to facilitate brachytherapy device swap
US9067063B2 (en) 2010-11-03 2015-06-30 Cianna Medical, Inc. Expandable brachytherapy apparatus and methods for using them
US10342992B2 (en) 2011-01-06 2019-07-09 Hologic, Inc. Orienting a brachytherapy applicator
DE102011110615A1 (en) * 2011-08-16 2013-02-21 Carl Zeiss Meditec Ag Generation of a defined radiation dose rate curve
JP6328110B2 (en) 2012-07-17 2018-05-23 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． Determination device for determining the orientation and shape of an introduction element
EP2962309B1 (en) 2013-02-26 2022-02-16 Accuray, Inc. Electromagnetically actuated multi-leaf collimator
WO2015008188A1 (en) 2013-07-17 2015-01-22 Koninklijke Philips N.V. Portal imaging for brachytherapy
CN107158581B (en) * 2017-05-15 2019-11-22 中国医学科学院肿瘤医院 Radiotherapy system in radiotherapy planning parameters of scanning paths method and art in art
RU2664191C1 (en) * 2017-07-17 2018-08-15 Федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет им. Н.Н. Бурденко" Министерства здравоохранения Российской Федерации Method of organ-preserving treatment of localized breast cancer
JP2020532364A (en) * 2017-08-31 2020-11-12 メイヨ フオンデーシヨン フオー メデイカル エジユケーシヨン アンド リサーチ Carbon particle therapy systems and methods for the treatment of cardiac arrhythmias and other disorders
KR102098254B1 (en) 2018-01-17 2020-05-26 사회복지법인 삼성생명공익재단 Evaluation system for radiodermatitis and evaluation method using the same
CN112057736B (en) * 2020-09-18 2022-02-22 张鲁燕 Cervical cancer afterloading radiotherapy applicator
DE102022209110A1 (en) 2022-09-01 2024-03-07 Carl Zeiss Meditec Ag Radiotherapy arrangement and method for operating a radiotherapy arrangement

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251059B1 (en) * 1997-09-11 2001-06-26 Cook Incorporated Medical radiation treatment delivery apparatus
US6320935B1 (en) * 2000-02-28 2001-11-20 X-Technologies, Ltd. Dosimeter for a miniature energy transducer for emitting X-ray radiation
US6402689B1 (en) * 1998-09-30 2002-06-11 Sicel Technologies, Inc. Methods, systems, and associated implantable devices for dynamic monitoring of physiological and biological properties of tumors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4598415A (en) 1982-09-07 1986-07-01 Imaging Sciences Associates Limited Partnership Method and apparatus for producing X-rays
JPS60193477A (en) * 1984-03-14 1985-10-01 日本電気株式会社 Radioactive ray irradiation apparatus
US5653683A (en) * 1995-02-28 1997-08-05 D'andrea; Mark A. Intracavitary catheter for use in therapeutic radiation procedures
JPH09164216A (en) * 1995-12-14 1997-06-24 Hitachi Medical Corp Radiotherapy equipment
JPH11178942A (en) * 1997-12-17 1999-07-06 Olympus Optical Co Ltd Radio therapeutic device with small radiation source
DE19854287A1 (en) * 1998-11-19 2000-06-08 Juergen Leonhardt Device for preventing restenosis after angioplasty; has fine focus X-ray tube in catheter head outside patient, where catheter forms flexible X-ray wave conductor and has dispersion appliance for X-radiation at far end
EP1316330A1 (en) * 2001-11-29 2003-06-04 Nucletron B.V. Quality assurance for brachytherapy using a dose measuring system

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251059B1 (en) * 1997-09-11 2001-06-26 Cook Incorporated Medical radiation treatment delivery apparatus
US6402689B1 (en) * 1998-09-30 2002-06-11 Sicel Technologies, Inc. Methods, systems, and associated implantable devices for dynamic monitoring of physiological and biological properties of tumors
US6320935B1 (en) * 2000-02-28 2001-11-20 X-Technologies, Ltd. Dosimeter for a miniature energy transducer for emitting X-ray radiation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1658110A4 *

Also Published As

Publication number Publication date
KR100990553B1 (en) 2010-10-29
US7322929B2 (en) 2008-01-29
EP1658110A2 (en) 2006-05-24
KR20060011893A (en) 2006-02-03
JP2007526010A (en) 2007-09-13
EP1658110A4 (en) 2010-07-28
WO2004112890A2 (en) 2004-12-29
US20040260142A1 (en) 2004-12-23
WO2004112890A9 (en) 2005-02-03

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