WO2005029046A3 - A multi-spectral optical method and system for detecting and classifying biological and non-biological particles - Google Patents

A multi-spectral optical method and system for detecting and classifying biological and non-biological particles Download PDF

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Publication number
WO2005029046A3
WO2005029046A3 PCT/US2004/013672 US2004013672W WO2005029046A3 WO 2005029046 A3 WO2005029046 A3 WO 2005029046A3 US 2004013672 W US2004013672 W US 2004013672W WO 2005029046 A3 WO2005029046 A3 WO 2005029046A3
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WO
WIPO (PCT)
Prior art keywords
biological
detecting
optical method
spectral optical
classifying
Prior art date
Application number
PCT/US2004/013672
Other languages
French (fr)
Other versions
WO2005029046A2 (en
Inventor
David B Silcott
Alexander Fielding
Original Assignee
S3I Llc
David B Silcott
Alexander Fielding
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by S3I Llc, David B Silcott, Alexander Fielding filed Critical S3I Llc
Priority to JP2006514234A priority Critical patent/JP4598766B2/en
Priority to CA2524345A priority patent/CA2524345C/en
Priority to EP04809349A priority patent/EP1620710A2/en
Priority to AU2004274855A priority patent/AU2004274855B2/en
Publication of WO2005029046A2 publication Critical patent/WO2005029046A2/en
Publication of WO2005029046A3 publication Critical patent/WO2005029046A3/en
Priority to IL171663A priority patent/IL171663A/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/22—Devices for withdrawing samples in the gaseous state
    • G01N1/2273—Atmospheric sampling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1434—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N2001/022—Devices for withdrawing samples sampling for security purposes, e.g. contraband, warfare agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/22—Devices for withdrawing samples in the gaseous state
    • G01N1/2202—Devices for withdrawing samples in the gaseous state involving separation of sample components during sampling
    • G01N2001/222—Other features
    • G01N2001/2223—Other features aerosol sampling devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1477—Multiparameters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N2015/1493—Particle size

Abstract

Enhanced methods, apparatuses and systems are disclosed for the real-time detection and classification of biological and non-biological particles by substantially simultaneously measuring a single particle's characteristics in terms of size and density, elastic scattering properties, and absorption and fluorescence.
PCT/US2004/013672 2003-04-29 2004-04-29 A multi-spectral optical method and system for detecting and classifying biological and non-biological particles WO2005029046A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2006514234A JP4598766B2 (en) 2003-04-29 2004-04-29 Multispectral optical method and system for detecting and classifying biological and non-biological microparticles
CA2524345A CA2524345C (en) 2003-04-29 2004-04-29 A multi-spectral optical method and system for detecting and classifying biological and non-biological particles
EP04809349A EP1620710A2 (en) 2003-04-29 2004-04-29 A multi-spectral optical method and system for detecting and classifying biological and non-biological particles
AU2004274855A AU2004274855B2 (en) 2003-04-29 2004-04-29 A multi-spectral optical method and system for detecting and classifying biological and non-biological particles
IL171663A IL171663A (en) 2003-04-29 2005-10-30 Multi-spectral optical method and system for detecting and classifying biological and non-biological particles

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46604203P 2003-04-29 2003-04-29
US60/466,042 2003-04-29

Publications (2)

Publication Number Publication Date
WO2005029046A2 WO2005029046A2 (en) 2005-03-31
WO2005029046A3 true WO2005029046A3 (en) 2005-06-16

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/013672 WO2005029046A2 (en) 2003-04-29 2004-04-29 A multi-spectral optical method and system for detecting and classifying biological and non-biological particles

Country Status (7)

Country Link
US (1) US7106442B2 (en)
EP (1) EP1620710A2 (en)
JP (1) JP4598766B2 (en)
AU (1) AU2004274855B2 (en)
CA (1) CA2524345C (en)
IL (1) IL171663A (en)
WO (1) WO2005029046A2 (en)

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CN106662572B (en) * 2015-02-12 2019-07-05 深圳迈瑞生物医疗电子股份有限公司 Cytoanalyze, method for classifying particles and device

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