WO2005039688A3 - Patient sensory response evaluation for neuromodulation efficacy rating - Google Patents

Patient sensory response evaluation for neuromodulation efficacy rating Download PDF

Info

Publication number
WO2005039688A3
WO2005039688A3 PCT/US2004/029851 US2004029851W WO2005039688A3 WO 2005039688 A3 WO2005039688 A3 WO 2005039688A3 US 2004029851 W US2004029851 W US 2004029851W WO 2005039688 A3 WO2005039688 A3 WO 2005039688A3
Authority
WO
WIPO (PCT)
Prior art keywords
patient
neuromodulation
delivery
stimuli
sensory
Prior art date
Application number
PCT/US2004/029851
Other languages
French (fr)
Other versions
WO2005039688A2 (en
Inventor
Gary W King
Original Assignee
Medtronic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Inc filed Critical Medtronic Inc
Priority to EP04809738A priority Critical patent/EP1687061A2/en
Publication of WO2005039688A2 publication Critical patent/WO2005039688A2/en
Publication of WO2005039688A3 publication Critical patent/WO2005039688A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36021—External stimulators, e.g. with patch electrodes for treatment of pain
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/70—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mental therapies, e.g. psychological therapy or autogenous training
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36025—External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36071—Pain

Abstract

The invention is directed to a technique for rating neuromodulation efficacy based on evaluation of the response of the patient to sensory stimuli with and without delivery of neuromodulation therapy. In addition, the invention may provide a system capable of delivering sensory stimuli on a quantitative basis in a coordinated manner with delivery of neuromodulation therapy. A device programmer may provide a platform for controlling delivery of the sensory stimuli, delivery of neuromodulation therapy, and generation of rating information for neuromodulation efficacy based on patient sensory response to the stimuli. In operation, the programmer controls application of selected sensory stimuli to the patient's body and records the patient's verbal or physiological responses to the stimuli. This invention can be used to be a diagnostic or prognostic test that a given neuromodulation therapy, such as neurostimulation or drug delivery, is and will be successful.
PCT/US2004/029851 2003-10-02 2004-09-14 Patient sensory response evaluation for neuromodulation efficacy rating WO2005039688A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP04809738A EP1687061A2 (en) 2003-10-02 2004-09-14 Patient sensory response evaluation for neuromodulation efficacy rating

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US50831803P 2003-10-02 2003-10-02
US60/508,318 2003-10-02
US50835403P 2003-10-03 2003-10-03
US60/508,354 2003-10-03
US10/768,352 2004-01-30
US10/768,352 US7206632B2 (en) 2003-10-02 2004-01-30 Patient sensory response evaluation for neuromodulation efficacy rating

Publications (2)

Publication Number Publication Date
WO2005039688A2 WO2005039688A2 (en) 2005-05-06
WO2005039688A3 true WO2005039688A3 (en) 2005-06-23

Family

ID=34397033

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/029851 WO2005039688A2 (en) 2003-10-02 2004-09-14 Patient sensory response evaluation for neuromodulation efficacy rating

Country Status (3)

Country Link
US (2) US7206632B2 (en)
EP (1) EP1687061A2 (en)
WO (1) WO2005039688A2 (en)

Families Citing this family (116)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7837719B2 (en) 2002-05-09 2010-11-23 Daemen College Electrical stimulation unit and waterbath system
US20050181341A1 (en) * 2004-02-12 2005-08-18 Ewing Donald P. Self-contained electronic musculoskeletal stimulation apparatus and method of use
US7463927B1 (en) * 2004-09-02 2008-12-09 Intelligent Neurostimulation Microsystems, Llc Self-adaptive system for the automatic detection of discomfort and the automatic generation of SCS therapies for chronic pain control
US20060052720A1 (en) * 2004-09-03 2006-03-09 Ross David B Evaluation of pain in humans
US8560041B2 (en) 2004-10-04 2013-10-15 Braingate Co., Llc Biological interface system
US7991461B2 (en) 2005-01-06 2011-08-02 Braingate Co., Llc Patient training routine for biological interface system
WO2006074029A2 (en) * 2005-01-06 2006-07-13 Cyberkinetics Neurotechnology Systems, Inc. Neurally controlled and multi-device patient ambulation systems and related methods
US8095209B2 (en) 2005-01-06 2012-01-10 Braingate Co., Llc Biological interface system with gated control signal
WO2006076478A2 (en) * 2005-01-12 2006-07-20 Aspect Medical Systems, Inc. System and method for prediction of adverse events during treatment of psychological and neurological disorders
US8744585B2 (en) 2005-02-23 2014-06-03 Medtronics, Inc. Implantable medical device providing adaptive neurostimulation therapy for incontinence
US7680540B2 (en) * 2005-07-29 2010-03-16 Medtronic, Inc. Multi-application trial stimulator
US20070173903A1 (en) * 2005-08-30 2007-07-26 Bioq, Inc. Medical device for restoration of neurological function impaired by peripheral neuropathy
US20070073361A1 (en) * 2005-09-23 2007-03-29 Bioq, Inc. Medical device for restoration of autonomic and immune functions impaired by neuropathy
US8041429B2 (en) * 2005-10-18 2011-10-18 Ric Investments, Llc System and method for controlling hypothalamic function via vestibular stimulation
US20070129769A1 (en) * 2005-12-02 2007-06-07 Medtronic, Inc. Wearable ambulatory data recorder
US7801601B2 (en) * 2006-01-27 2010-09-21 Cyberonics, Inc. Controlling neuromodulation using stimulus modalities
US7715920B2 (en) * 2006-04-28 2010-05-11 Medtronic, Inc. Tree-based electrical stimulator programming
US8380300B2 (en) * 2006-04-28 2013-02-19 Medtronic, Inc. Efficacy visualization
US8306624B2 (en) 2006-04-28 2012-11-06 Medtronic, Inc. Patient-individualized efficacy rating
US8666506B2 (en) * 2006-06-30 2014-03-04 Medtronic, Inc. Selecting electrode combinations for stimulation therapy
US8103341B2 (en) * 2006-08-25 2012-01-24 Cardiac Pacemakers, Inc. System for abating neural stimulation side effects
WO2008031209A1 (en) * 2006-09-16 2008-03-20 Terence Gilhuly Improved sensors and sensing for monitoring neuromuscular blockade
US8540515B2 (en) * 2006-11-27 2013-09-24 Pharos Innovations, Llc Optimizing behavioral change based on a population statistical profile
US8540516B2 (en) * 2006-11-27 2013-09-24 Pharos Innovations, Llc Optimizing behavioral change based on a patient statistical profile
US8540517B2 (en) * 2006-11-27 2013-09-24 Pharos Innovations, Llc Calculating a behavioral path based on a statistical profile
US20080213736A1 (en) * 2006-12-28 2008-09-04 Jon Morris Method and apparatus for emotional profiling
US20080171929A1 (en) * 2007-01-11 2008-07-17 Katims Jefferson J Method for standardizing spacing between electrodes, and medical tape electrodes
AU2008227875B2 (en) 2007-03-19 2014-06-12 Insuline Medical Ltd. Drug delivery device
US9220837B2 (en) 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
US7801618B2 (en) * 2007-06-22 2010-09-21 Neuropace, Inc. Auto adjusting system for brain tissue stimulator
US8444571B2 (en) 2007-09-25 2013-05-21 Uroval, Inc. Obtaining measurements of muscle reflexes for diagnosis of patient symptoms
US7854703B2 (en) * 2007-09-25 2010-12-21 Intel Corporation Peripheral neuropathy detection
US9730605B2 (en) 2007-09-25 2017-08-15 Uroval, Inc. Diagnosis of brain and spinal cord injury by bulbocavernosus reflex measurement
WO2009042818A1 (en) 2007-09-25 2009-04-02 First Choice For Continence, Inc. Obtaining measurements of muscle reflexes for diagnosis of patient symptoms
EP2211988A1 (en) * 2007-10-24 2010-08-04 Medtronic, Inc. Remote titration of therapy delivered by an implantable medical device
US20090149797A1 (en) * 2007-12-05 2009-06-11 Searete Llc, A Limited Liability Corporation Of The State Of Delaware System for reversible chemical modulation of neural activity
US8165668B2 (en) * 2007-12-05 2012-04-24 The Invention Science Fund I, Llc Method for magnetic modulation of neural conduction
US8170658B2 (en) * 2007-12-05 2012-05-01 The Invention Science Fund I, Llc System for electrical modulation of neural conduction
US8180447B2 (en) 2007-12-05 2012-05-15 The Invention Science Fund I, Llc Method for reversible chemical modulation of neural activity
US8165669B2 (en) * 2007-12-05 2012-04-24 The Invention Science Fund I, Llc System for magnetic modulation of neural conduction
US8989858B2 (en) 2007-12-05 2015-03-24 The Invention Science Fund I, Llc Implant system for chemical modulation of neural activity
US8180446B2 (en) * 2007-12-05 2012-05-15 The Invention Science Fund I, Llc Method and system for cyclical neural modulation based on activity state
US8170659B2 (en) 2007-12-05 2012-05-01 The Invention Science Fund I, Llc Method for thermal modulation of neural activity
US8195287B2 (en) * 2007-12-05 2012-06-05 The Invention Science Fund I, Llc Method for electrical modulation of neural conduction
EP2231229A1 (en) 2007-12-18 2010-09-29 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
JP2009178456A (en) * 2008-01-31 2009-08-13 Nippon Koden Corp Autonomic nerve activity measuring apparatus and measuring method
US8892210B2 (en) * 2008-07-02 2014-11-18 Niveus Medical, Inc. Devices, systems, and methods for automated optimization of energy delivery
US9610039B2 (en) * 2008-07-17 2017-04-04 Prosenex, LLC Hand-held neuroscreening device
WO2010008592A2 (en) 2008-07-17 2010-01-21 Electronic Products Accessories And Chemicals Llc Neuropathy diagnostic device
EP2313148B1 (en) 2008-07-30 2013-08-21 Ecole Polytechnique Fédérale de Lausanne Apparatus for optimized stimulation of a neurological target
US20100049265A1 (en) * 2008-08-22 2010-02-25 Dymedix Corporation EMI/ESD hardened sensor interface for a closed loop neuromodulator
US20100069771A1 (en) * 2008-09-12 2010-03-18 Dymedix Corporation Wireless pyro/piezo sensor
US8249701B2 (en) * 2008-10-15 2012-08-21 Spinal Modulation, Inc. Methods, devices and systems for programming neurostimulation
EP2355758A2 (en) 2008-11-07 2011-08-17 Insuline Medical Ltd. Device and method for drug delivery
CA2743575C (en) 2008-11-12 2017-01-31 Ecole Polytechnique Federale De Lausanne Microfabricated neurostimulation device
EP2395916A1 (en) 2009-02-12 2011-12-21 Ramot at Tel-Aviv University Ltd Method and system for detecting neuropathy
US20170246481A1 (en) * 2009-11-11 2017-08-31 David J Mishelevich Devices and methods for optimized neuromodulation and their application
CA2782710C (en) 2009-12-01 2019-01-22 Ecole Polytechnique Federale De Lausanne Microfabricated neurostimulation device and methods of making and using the same
US8670833B2 (en) * 2009-12-04 2014-03-11 Boston Scientific Neuromodulation Corporation Methods and apparatus for using sensors with a deep brain stimulation system
EP2552536B1 (en) 2010-04-01 2016-06-08 Ecole Polytechnique Fédérale de Lausanne (EPFL) Device for interacting with neurological tissue
US10758723B2 (en) 2011-05-19 2020-09-01 Neuros Medical, Inc. Nerve cuff electrode for neuromodulation in large human nerve trunks
US11413458B2 (en) 2011-05-19 2022-08-16 Neuros Medical, Inc. Nerve cuff electrode for neuromodulation in large human nerve trunks
AU2012334926B2 (en) 2011-11-11 2017-07-13 The Regents Of The University Of California Transcutaneous spinal cord stimulation: noninvasive tool for activation of locomotor circuitry
AU2013230893B2 (en) * 2012-03-08 2015-12-03 Medtronic Af Luxembourg S.A.R.L. Neuromodulation and associated systems and methods for the management of pain
JP2015515906A (en) * 2012-05-09 2015-06-04 メドック リミテッド． Improved temperature stimulation probe and method
US9731133B1 (en) 2013-01-22 2017-08-15 Nevro Corp. Systems and methods for systematically testing a plurality of therapy programs in patient therapy devices
US9895538B1 (en) 2013-01-22 2018-02-20 Nevro Corp. Systems and methods for deploying patient therapy devices
US9295840B1 (en) 2013-01-22 2016-03-29 Nevro Corporation Systems and methods for automatically programming patient therapy devices
US9993642B2 (en) 2013-03-15 2018-06-12 The Regents Of The University Of California Multi-site transcutaneous electrical stimulation of the spinal cord for facilitation of locomotion
JP2016523125A (en) 2013-05-30 2016-08-08 グラハム エイチ． クリーシー Local nervous stimulation
US11229789B2 (en) 2013-05-30 2022-01-25 Neurostim Oab, Inc. Neuro activator with controller
US20150273215A1 (en) * 2014-03-26 2015-10-01 Pacesetter, Inc. Systems and methods for assessment of pain and other parameters during trial neurostimulation
US10137299B2 (en) 2013-09-27 2018-11-27 The Regents Of The University Of California Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects
EP3048966A4 (en) * 2013-09-29 2016-10-19 Medasense Biometrics Ltd Device and method for determining spinal cord stimulation efficacy
CN106455985B (en) 2014-05-16 2019-09-17 阿莱瓦神经治疗股份有限公司 With the device and production and preparation method thereof of nerve fiber interaction
US11311718B2 (en) 2014-05-16 2022-04-26 Aleva Neurotherapeutics Sa Device for interacting with neurological tissue and methods of making and using the same
US10155114B2 (en) * 2014-06-03 2018-12-18 Dirk De Ridder Systems and methods of treating a neurological disorder in a patient
US10751533B2 (en) 2014-08-21 2020-08-25 The Regents Of The University Of California Regulation of autonomic control of bladder voiding after a complete spinal cord injury
US9403011B2 (en) 2014-08-27 2016-08-02 Aleva Neurotherapeutics Leadless neurostimulator
CA2959378A1 (en) 2014-08-27 2016-03-03 The Regents Of The University Of California Multi-electrode array for spinal cord epidural stimulation
US9474894B2 (en) 2014-08-27 2016-10-25 Aleva Neurotherapeutics Deep brain stimulation lead
US20150025334A1 (en) * 2014-09-09 2015-01-22 Lakshya JAIN Method and system for monitoring pain of patients
US11077301B2 (en) 2015-02-21 2021-08-03 NeurostimOAB, Inc. Topical nerve stimulator and sensor for bladder control
US9517344B1 (en) 2015-03-13 2016-12-13 Nevro Corporation Systems and methods for selecting low-power, effective signal delivery parameters for an implanted pulse generator
US9717903B1 (en) * 2015-03-17 2017-08-01 Gary Barrett Electronic process to restore, improve and/or strengthen the libido; method to mend the sex drive in males and females
US11298533B2 (en) 2015-08-26 2022-04-12 The Regents Of The University Of California Concerted use of noninvasive neuromodulation device with exoskeleton to enable voluntary movement and greater muscle activation when stepping in a chronically paralyzed subject
AU2016325450A1 (en) * 2015-09-21 2018-05-10 Boston Scientific Neuromodulation Corporation Automated program optimization
US11097122B2 (en) 2015-11-04 2021-08-24 The Regents Of The University Of California Magnetic stimulation of the spinal cord to restore control of bladder and/or bowel
US10300277B1 (en) 2015-12-14 2019-05-28 Nevro Corp. Variable amplitude signals for neurological therapy, and associated systems and methods
WO2017134587A1 (en) 2016-02-02 2017-08-10 Aleva Neurotherapeutics, Sa Treatment of autoimmune diseases with deep brain stimulation
US20170224522A1 (en) * 2016-02-05 2017-08-10 Global Health & Innovation Vacuum therapy apparatus
US10786674B2 (en) * 2016-03-08 2020-09-29 Medtronic, Inc. Medical therapy target definition
US10799701B2 (en) * 2016-03-30 2020-10-13 Nevro Corp. Systems and methods for identifying and treating patients with high-frequency electrical signals
US11446504B1 (en) 2016-05-27 2022-09-20 Nevro Corp. High frequency electromagnetic stimulation for modulating cells, including spontaneously active and quiescent cells, and associated systems and methods
CN106880342A (en) * 2017-03-21 2017-06-23 中山大学附属第医院 A kind of diabetes tactile and pain sensation lesion detection device
EP3421081B1 (en) 2017-06-30 2020-04-15 GTX medical B.V. A system for neuromodulation
KR101950342B1 (en) * 2017-07-14 2019-05-08 재단법인 아산사회복지재단 System, method and program for providing pain improvement training
US11006897B2 (en) 2017-07-18 2021-05-18 Forest Devices, Inc. Electrode array apparatus, neurological condition detection apparatus, and method of using the same
WO2019094365A1 (en) 2017-11-07 2019-05-16 Neurostim Oab, Inc. Non-invasive nerve activator with adaptive circuit
AU2018385603A1 (en) 2017-12-13 2020-07-02 Neuros Medical, Inc. Nerve cuff deployment devices
US10702692B2 (en) 2018-03-02 2020-07-07 Aleva Neurotherapeutics Neurostimulation device
AU2019253298A1 (en) 2018-04-09 2020-10-29 Neuros Medical, Inc. Apparatuses and methods for setting an electrical dose
EP3873335A4 (en) * 2018-11-02 2022-07-27 Saluda Medical Pty Ltd Characterisation of neurostimulation therapeutic efficacy
ES2911465T3 (en) 2018-11-13 2022-05-19 Onward Medical N V Control system for the reconstruction and/or restoration of a patient's movement
AU2020207940A1 (en) * 2019-01-17 2021-08-12 Nevro Corp. Sensory threshold and/or adaptation for neurological therapy screening and/or parameter selection, and associated systems and methods
US11590352B2 (en) 2019-01-29 2023-02-28 Nevro Corp. Ramped therapeutic signals for modulating inhibitory interneurons, and associated systems and methods
EP3695878B1 (en) 2019-02-12 2023-04-19 ONWARD Medical N.V. A system for neuromodulation
EP3990100A4 (en) 2019-06-26 2023-07-19 Neurostim Technologies LLC Non-invasive nerve activator with adaptive circuit
EP3827871A1 (en) 2019-11-27 2021-06-02 ONWARD Medical B.V. Neuromodulation system
JP2023506713A (en) 2019-12-16 2023-02-20 ニューロスティム テクノロジーズ エルエルシー Noninvasive nerve activator using booster charge delivery
AU2021219722A1 (en) 2020-02-11 2022-09-08 Neuros Medical, Inc. System and method for quantifying qualitative patient-reported data sets
USD1018861S1 (en) 2021-04-07 2024-03-19 Forest Devices, Inc. Headgear
US11266476B1 (en) 2021-04-07 2022-03-08 Forest Devices, Inc. Headgear storage device and method of distribution
US11241182B1 (en) 2021-04-07 2022-02-08 Forest Devices, Inc. Gel distribution apparatus and method
USD970019S1 (en) 2021-04-07 2022-11-15 Forest Devices, Inc. Gel distribution module

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6418344B1 (en) * 2000-02-24 2002-07-09 Electrocore Techniques, Llc Method of treating psychiatric disorders by electrical stimulation within the orbitofrontal cerebral cortex
US6612983B1 (en) * 2000-03-28 2003-09-02 Medtronic, Inc. Pancreatic secretion response to stimulation test protocol
WO2003072025A2 (en) * 2002-02-21 2003-09-04 Biovail Laboratories Inc. Modified release formulations of at least one form of tramadol

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2049431B (en) 1979-04-09 1983-05-18 Wyeth John & Brother Ltd Measuring device
US4503863A (en) 1979-06-29 1985-03-12 Katims Jefferson J Method and apparatus for transcutaneous electrical stimulation
US4305402A (en) 1979-06-29 1981-12-15 Katims Jefferson J Method for transcutaneous electrical stimulation
US4570640A (en) 1981-08-06 1986-02-18 Barsa John E Sensory monitoring apparatus and method
EP0236513A1 (en) 1986-02-13 1987-09-16 John E. Barsa Sensory monitoring apparatus and method
US4557271A (en) 1983-05-11 1985-12-10 Stoller Kenneth P Method and apparatus for detecting body illness, dysfunction, disease and/or pathology
US4640266A (en) 1984-08-29 1987-02-03 Zubin Levy Sensory stimulation enclosure
GB8823765D0 (en) 1988-10-11 1988-11-16 Ici America Inc Method & instrument
US5018526A (en) 1989-02-28 1991-05-28 Gaston Johansson Fannie Apparatus and method for providing a multidimensional indication of pain
NL9000983A (en) 1990-04-24 1991-11-18 Univ Nijmegen APPARATUS AND METHOD FOR DETERMINING THE INFLUENCE OF ANESTHETICS ON HUMANS OR ANIMALS.
SE467561B (en) 1990-12-04 1992-08-10 Dorsograf Ab DEVICE FOR SEATING TRANSPORT TIME OF NERV SIGNALS
US5388587A (en) 1990-12-04 1995-02-14 Dorsograf Ab Method and apparatus for measuring the transport time of nerve signals excited in different dermatoms of a patient
US5199428A (en) 1991-03-22 1993-04-06 Medtronic, Inc. Implantable electrical nerve stimulator/pacemaker with ischemia for decreasing cardiac workload
US5233984A (en) 1991-03-29 1993-08-10 Medtronic, Inc. Implantable multi-axis position and activity sensor
US5191896A (en) 1991-06-28 1993-03-09 Medoc Ltd. Apparatus for measuring threshold sensitivity to a stimulus
US5370672A (en) 1992-10-30 1994-12-06 The Johns Hopkins University Computer-controlled neurological stimulation system
CA2100849A1 (en) 1993-07-19 1995-01-20 Anthony John Brammer Method for identifying vibrotactile perception thresholds of nerve endings with inconsistent subject response rejection
US6249703B1 (en) 1994-07-08 2001-06-19 Medtronic, Inc. Handheld patient programmer for implantable human tissue stimulator
US5443486A (en) 1994-09-26 1995-08-22 Medtronic, Inc. Method and apparatus to limit control of parameters of electrical tissue stimulators
US5692500A (en) 1995-01-09 1997-12-02 Gaston-Johansson; Fannie Pain measurement and recording tool and method
US5797854A (en) 1995-08-01 1998-08-25 Hedgecock; James L. Method and apparatus for testing and measuring current perception threshold and motor nerve junction performance
US5806522A (en) 1995-08-15 1998-09-15 Katims; Jefferson Jacob Digital automated current perception threshold (CPT) determination device and method
US5662689A (en) 1995-09-08 1997-09-02 Medtronic, Inc. Method and apparatus for alleviating cardioversion shock pain
US5725472A (en) 1995-12-18 1998-03-10 Weathers; Lawrence R. Psychotherapy apparatus and method for the inputting and shaping new emotional physiological and cognitive response patterns in patients
SE508357C2 (en) 1996-01-02 1998-09-28 Kay Laserow Measuring instruments for measuring pain and a method for measuring pain with a measuring instrument
US6463328B1 (en) * 1996-02-02 2002-10-08 Michael Sasha John Adaptive brain stimulation method and system
US6066163A (en) * 1996-02-02 2000-05-23 John; Michael Sasha Adaptive brain stimulation method and system
US5702429A (en) 1996-04-04 1997-12-30 Medtronic, Inc. Neural stimulation techniques with feedback
WO1997037720A1 (en) 1996-04-04 1997-10-16 Medtronic, Inc. Living tissue stimulation and recording techniques
FR2796562B1 (en) 1996-04-04 2005-06-24 Medtronic Inc TECHNIQUES FOR STIMULATING LIVING TISSUE AND RECORDING WITH LOCAL CONTROL OF ACTIVE SITES
AU3304997A (en) * 1996-05-31 1998-01-05 Southern Illinois University Methods of modulating aspects of brain neural plasticity by vagus nerve stimulation
US5938690A (en) * 1996-06-07 1999-08-17 Advanced Neuromodulation Systems, Inc. Pain management system and method
US5941833A (en) 1997-06-04 1999-08-24 Neuroscience Toolworks, Inc. Heatbeam dolorimeter for pain and sensory evaluation
US6018682A (en) 1998-04-30 2000-01-25 Medtronic, Inc. Implantable seizure warning system
IL125053A (en) 1998-06-22 2004-07-25 Sorin T Teich Method for the detection of inflammatory processes and malignancies in mammals
US6027456A (en) 1998-07-10 2000-02-22 Advanced Neuromodulation Systems, Inc. Apparatus and method for positioning spinal cord stimulation leads
US6366813B1 (en) 1998-08-05 2002-04-02 Dilorenzo Daniel J. Apparatus and method for closed-loop intracranical stimulation for optimal control of neurological disease
US6615081B1 (en) * 1998-10-26 2003-09-02 Birinder R. Boveja Apparatus and method for adjunct (add-on) treatment of diabetes by neuromodulation with an external stimulator
US20060122660A1 (en) * 1998-10-26 2006-06-08 Boveja Birinder R Method and system for modulating sacral nerves and/or its branches in a patient to provide therapy for urological disorders and/or fecal incontinence, using rectangular and/or complex electrical pulses
US6113552A (en) 1998-11-18 2000-09-05 International Medical Device Partners, Inc. Pain measurement system and method
JP2000342690A (en) 1999-06-09 2000-12-12 Nippon Colin Co Ltd Anesthetic depth monitoring device
US6654642B2 (en) 1999-09-29 2003-11-25 Medtronic, Inc. Patient interactive neurostimulation system and method
US6308102B1 (en) 1999-09-29 2001-10-23 Stimsoft, Inc. Patient interactive neurostimulation system and method
US6644321B1 (en) 1999-10-29 2003-11-11 Medtronic, Inc. Tactile feedback for indicating validity of communication link with an implantable medical device
US6929607B2 (en) 1999-12-02 2005-08-16 Neuroscience Toolworks, Inc. Comprehensive pain assessment systems and methods
US20020026223A1 (en) 1999-12-24 2002-02-28 Riff Kenneth M. Method and a system for using implanted medical device data for accessing therapies
MXPA02007262A (en) 2000-01-29 2002-12-09 Paul E Thomson Detection and quantification of joint and tissue inflammation.
US6687538B1 (en) * 2000-06-19 2004-02-03 Medtronic, Inc. Trial neuro stimulator with lead diagnostics
US6757558B2 (en) 2000-07-06 2004-06-29 Algodyne, Ltd. Objective pain measurement system and method
US6847849B2 (en) 2000-11-15 2005-01-25 Medtronic, Inc. Minimally invasive apparatus for implanting a sacral stimulation lead
ATE539681T1 (en) * 2001-01-30 2012-01-15 R Christopher Decharms METHODS FOR PHYSIOLOGICAL MONITORING, TRAINING AND REGULATION
US6547746B1 (en) * 2001-08-27 2003-04-15 Andrew A. Marino Method and apparatus for determining response thresholds
US6647299B2 (en) 2001-09-21 2003-11-11 Medtronic, Inc. Patient programmer for implantable medical device with audio locator signal
US6702767B1 (en) 2001-09-25 2004-03-09 Nelson R. Douglas Multisensory stimulation system and method
US20030208247A1 (en) 2001-09-28 2003-11-06 Michele Spinelli Implantable stimulation lead with tissue in-growth anchor
US7187978B2 (en) 2001-11-01 2007-03-06 Medtronic, Inc. Method and apparatus for programming an implantable medical device
US20030105413A1 (en) 2001-11-02 2003-06-05 Bleustein Clifford B. Non-invasive, quantitative somatosensory method for the evaluation of erectile dysfunction
US20030204274A1 (en) 2002-04-26 2003-10-30 Medtronic, Inc. Patient controlled activation with implantable drug delivery devices
AU2003251486A1 (en) 2002-06-12 2003-12-31 Joseph Arezzo A non-invasive, quantitative somatosensory method for the evaluation of erectile dysfunction
WO2004036372A2 (en) 2002-10-15 2004-04-29 Medtronic Inc. Scoring of sensed neurological signals for use with a medical device system
AU2003287162A1 (en) 2002-10-15 2004-05-04 Medtronic Inc. Configuring and testing treatment therapy parameters for a medical device system
US7089927B2 (en) 2002-10-23 2006-08-15 New York University System and method for guidance of anesthesia, analgesia and amnesia
AU2003285079A1 (en) 2002-10-31 2004-06-07 Medtronic, Inc. Neurostimulation therapy manipulation
WO2004041351A1 (en) 2002-10-31 2004-05-21 Medtronic, Inc. Method and device for applying filter information to identify combinations of electrodes
ATE337048T1 (en) 2002-10-31 2006-09-15 Medtronic Inc FAIL-PROOF PROGRAMMING OF AN IMPLANTABLE MEDICAL DEVICE
WO2004041352A1 (en) 2002-10-31 2004-05-21 Medtronic, Inc. Distributed system for neurostimulation therapy programming
AU2003288959A1 (en) 2002-10-31 2004-06-07 Medtronic, Inc. Body region indication
US7035690B2 (en) 2002-11-15 2006-04-25 Medtronic, Inc. Human-implantable-neurostimulator user interface having multiple levels of abstraction
BRPI0410296A (en) * 2003-05-06 2006-05-16 Aspect Medical Systems Inc system and method for determining the efficacy of treatment of neurological disorders using electroencephalogram
US8041418B2 (en) * 2004-12-17 2011-10-18 Medtronic, Inc. System and method for regulating cardiac triggered therapy to the brain

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6418344B1 (en) * 2000-02-24 2002-07-09 Electrocore Techniques, Llc Method of treating psychiatric disorders by electrical stimulation within the orbitofrontal cerebral cortex
US6612983B1 (en) * 2000-03-28 2003-09-02 Medtronic, Inc. Pancreatic secretion response to stimulation test protocol
WO2003072025A2 (en) * 2002-02-21 2003-09-04 Biovail Laboratories Inc. Modified release formulations of at least one form of tramadol

Also Published As

Publication number Publication date
US7367956B2 (en) 2008-05-06
US20050075669A1 (en) 2005-04-07
EP1687061A2 (en) 2006-08-09
US7206632B2 (en) 2007-04-17
WO2005039688A2 (en) 2005-05-06
US20060270944A1 (en) 2006-11-30

Similar Documents

Publication Publication Date Title
WO2005039688A3 (en) Patient sensory response evaluation for neuromodulation efficacy rating
Khodaparast et al. Vagus nerve stimulation delivered during motor rehabilitation improves recovery in a rat model of stroke
AU2004279285B2 (en) Automatic therapy adjustments
WO2005084389A3 (en) External baroreflex activation
JP6568803B2 (en) Electrical stimulation system with pulse control
Morris Iii A retrospective analysis of the effects of magnet-activated stimulation in conjunction with vagus nerve stimulation therapy
WO2002089655A3 (en) Submucosal gastric implant device and method
US20140336722A1 (en) Method and neuroprosthetic device for monitoring and suppression of pathological tremors through neurostimulation of the afferent pathways
WO2005000153A3 (en) Systems and methods for facilitating and/or effectuating development, rehabilitation, restoration, and/or recovery of visual function through neural stimulation
WO2005027839A3 (en) Methods and reagents for the treatment of immunoinflammatory disorders
ATE499143T1 (en) CONTEXT-SENSITIVE COLLECTION OF NEUROSTIMULATION THERAPY DATA
WO2004062470A3 (en) System and method for stimulation of a person’s brain stem
WO2004030585A3 (en) User interface for medical device
ATE333921T1 (en) DEFIBRILLATORS ADAPTED TO INTENDED PATIENTS
IL166571A0 (en) Medical treatment system by substituting native biological regulatory function: cardiac pacing system blood pressure regulating system and cardiac disease treatment system based on the medical system
WO2008057244A3 (en) Paitient management system for providing data for an implantable medical device
FR2848861B1 (en) ACTIVE MEDICAL DEVICE, IN PARTICULAR IMPLANTABLE DEVICE SUCH AS CARDIAC STIMULATOR, DEFIBRILLATOR, CARDIOVERTER OR MULTISITE DEVICE, COMPRISING MEANS FOR DETECTING SLEEP DISORDERS
CA2275504A1 (en) Pharmacogenetic methods for use in the treatment of nervous system diseases
Khanna Implantable medical electronics
WO2002053106A3 (en) Autoantigen composition
US6041259A (en) Externally worn medical device
SE0102147D0 (en) New methods
Steketee et al. Obsessive compulsive disorder: The latest assessment and treatment strategies.
WO2003099105A3 (en) Diagnosis and treatment of human dormancy syndrome
WO2002058532A3 (en) Method for identifying ligands to lxr-receptor that stimulates pre-adipocyte differentiation and formulations thereof

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2004809738

Country of ref document: EP

DPEN Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed from 20040101)
WWP Wipo information: published in national office

Ref document number: 2004809738

Country of ref document: EP