WO2005046788A3 - Pacing system for diastolic dysfunction - Google Patents

Pacing system for diastolic dysfunction Download PDF

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Publication number
WO2005046788A3
WO2005046788A3 PCT/US2004/037129 US2004037129W WO2005046788A3 WO 2005046788 A3 WO2005046788 A3 WO 2005046788A3 US 2004037129 W US2004037129 W US 2004037129W WO 2005046788 A3 WO2005046788 A3 WO 2005046788A3
Authority
WO
WIPO (PCT)
Prior art keywords
diastolic
cardiac
pacing
diastolic dysfunction
pacing system
Prior art date
Application number
PCT/US2004/037129
Other languages
French (fr)
Other versions
WO2005046788A2 (en
Inventor
Rodney W Salo
Matthew Salo
Original Assignee
Cardiac Pacemakers Inc
Rodney W Salo
Matthew Salo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardiac Pacemakers Inc, Rodney W Salo, Matthew Salo filed Critical Cardiac Pacemakers Inc
Priority to EP04800869A priority Critical patent/EP1680179B1/en
Priority to JP2006539696A priority patent/JP4711966B2/en
Priority to AT04800869T priority patent/ATE516850T1/en
Publication of WO2005046788A2 publication Critical patent/WO2005046788A2/en
Publication of WO2005046788A3 publication Critical patent/WO2005046788A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/3627—Heart stimulators for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A61N1/36514—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure

Abstract

Pacing pulses are delivered to one or more cardiac regions to improve diastolic performance in patients having diastolic dysfunction and/or heart failure. A cardiac pacing system executes a pacing algorithm using a parameter indicative of the diastolic performance as an input. The pacing pulses excite the one or more cardiac regions to redistribute the loading on the ventricular wall during diastole, thereby improving the diastolic performance by lowering the degree of cardiac wall motion dyssynchrony associated with diastolic dysfunction.
PCT/US2004/037129 2003-11-07 2004-11-05 Pacing system for diastolic dysfunction WO2005046788A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP04800869A EP1680179B1 (en) 2003-11-07 2004-11-05 Pacing system for diastolic dysfunction
JP2006539696A JP4711966B2 (en) 2003-11-07 2004-11-05 Paging system for diastolic dysfunction
AT04800869T ATE516850T1 (en) 2003-11-07 2004-11-05 CARDIAC STIMULATION IN DIASTOLIC DYSFUNCTION

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/703,398 US9002452B2 (en) 2003-11-07 2003-11-07 Electrical therapy for diastolic dysfunction
US10/703,398 2003-11-07

Publications (2)

Publication Number Publication Date
WO2005046788A2 WO2005046788A2 (en) 2005-05-26
WO2005046788A3 true WO2005046788A3 (en) 2006-09-28

Family

ID=34551898

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/037129 WO2005046788A2 (en) 2003-11-07 2004-11-05 Pacing system for diastolic dysfunction

Country Status (5)

Country Link
US (1) US9002452B2 (en)
EP (2) EP2314347B1 (en)
JP (2) JP4711966B2 (en)
AT (1) ATE516850T1 (en)
WO (1) WO2005046788A2 (en)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030036746A1 (en) 2001-08-16 2003-02-20 Avi Penner Devices for intrabody delivery of molecules and systems and methods utilizing same
US7110817B2 (en) * 1998-05-08 2006-09-19 Cardiac Pacemakers, Inc. Method and apparatus for optimizing ventricular synchrony during DDD resynchronization therapy using adjustable atrio-ventricular delays
US7158830B2 (en) * 1998-05-08 2007-01-02 Cardiac Pacemakers, Inc. Method and apparatus for optimizing stroke volume during DDD resynchronization therapy using adjustable atrio-ventricular delays
US7127289B2 (en) * 2001-12-05 2006-10-24 Cardiac Pacemakers, Inc. Cardiac resynchronization system employing mechanical measurement of cardiac walls
US7041061B2 (en) * 2002-07-19 2006-05-09 Cardiac Pacemakers, Inc. Method and apparatus for quantification of cardiac wall motion asynchrony
US7972275B2 (en) 2002-12-30 2011-07-05 Cardiac Pacemakers, Inc. Method and apparatus for monitoring of diastolic hemodynamics
US9002452B2 (en) 2003-11-07 2015-04-07 Cardiac Pacemakers, Inc. Electrical therapy for diastolic dysfunction
US8086315B2 (en) 2004-02-12 2011-12-27 Asap Medical, Inc. Cardiac stimulation apparatus and method for the control of hypertension
EP1680016A1 (en) * 2004-05-06 2006-07-19 St. Jude Medical AB Detection of diastolic heart failure
US7209786B2 (en) * 2004-06-10 2007-04-24 Cardiac Pacemakers, Inc. Method and apparatus for optimization of cardiac resynchronization therapy using heart sounds
US20060064133A1 (en) 2004-09-17 2006-03-23 Cardiac Pacemakers, Inc. System and method for deriving relative physiologic measurements using an external computing device
US7813808B1 (en) 2004-11-24 2010-10-12 Remon Medical Technologies Ltd Implanted sensor system with optimized operational and sensing parameters
US8010191B2 (en) 2004-12-20 2011-08-30 Cardiac Pacemakers, Inc. Systems, devices and methods for monitoring efficiency of pacing
US8005544B2 (en) 2004-12-20 2011-08-23 Cardiac Pacemakers, Inc. Endocardial pacing devices and methods useful for resynchronization and defibrillation
US8010192B2 (en) 2004-12-20 2011-08-30 Cardiac Pacemakers, Inc. Endocardial pacing relating to conduction abnormalities
US8050756B2 (en) 2004-12-20 2011-11-01 Cardiac Pacemakers, Inc. Circuit-based devices and methods for pulse control of endocardial pacing in cardiac rhythm management
AR047851A1 (en) 2004-12-20 2006-03-01 Giniger Alberto German A NEW MARCAPASOS THAT RESTORES OR PRESERVES THE PHYSIOLOGICAL ELECTRIC DRIVING OF THE HEART AND A METHOD OF APPLICATION
US8290586B2 (en) 2004-12-20 2012-10-16 Cardiac Pacemakers, Inc. Methods, devices and systems for single-chamber pacing using a dual-chamber pacing device
US8014861B2 (en) 2004-12-20 2011-09-06 Cardiac Pacemakers, Inc. Systems, devices and methods relating to endocardial pacing for resynchronization
US8423139B2 (en) 2004-12-20 2013-04-16 Cardiac Pacemakers, Inc. Methods, devices and systems for cardiac rhythm management using an electrode arrangement
US7662104B2 (en) 2005-01-18 2010-02-16 Cardiac Pacemakers, Inc. Method for correction of posture dependence on heart sounds
US8565867B2 (en) 2005-01-28 2013-10-22 Cyberonics, Inc. Changeable electrode polarity stimulation by an implantable medical device
US9314633B2 (en) 2008-01-25 2016-04-19 Cyberonics, Inc. Contingent cardio-protection for epilepsy patients
US20060271121A1 (en) 2005-05-25 2006-11-30 Cardiac Pacemakers, Inc. Closed loop impedance-based cardiac resynchronization therapy systems, devices, and methods
US7922669B2 (en) 2005-06-08 2011-04-12 Cardiac Pacemakers, Inc. Ischemia detection using a heart sound sensor
GB2428977A (en) * 2005-08-08 2007-02-14 Ai Semi Ltd Pacemaker or defibrillator using combined electrogram and haemodynamic data
US9839781B2 (en) 2005-08-22 2017-12-12 Cardiac Pacemakers, Inc. Intracardiac impedance and its applications
US7742815B2 (en) 2005-09-09 2010-06-22 Cardiac Pacemakers, Inc. Using implanted sensors for feedback control of implanted medical devices
EP1933698A2 (en) * 2005-09-16 2008-06-25 The Ohio State University Method and apparatus for detecting intraventricular dyssynchrony
US8131043B2 (en) * 2005-09-16 2012-03-06 The Ohio State University Method and apparatus for detecting interventricular dyssynchrony
US7974691B2 (en) * 2005-09-21 2011-07-05 Cardiac Pacemakers, Inc. Method and apparatus for controlling cardiac resynchronization therapy using cardiac impedance
CN101304692B (en) * 2005-11-08 2012-11-07 皇家飞利浦电子股份有限公司 Ultrasonic diagnosis of myocardial synchronization
US8108034B2 (en) 2005-11-28 2012-01-31 Cardiac Pacemakers, Inc. Systems and methods for valvular regurgitation detection
US8682428B2 (en) * 2005-11-30 2014-03-25 St. Jude Medical Ab Implantable medical device with therapy control
US8615309B2 (en) 2006-03-29 2013-12-24 Catholic Healthcare West Microburst electrical stimulation of cranial nerves for the treatment of medical conditions
US7869871B2 (en) 2006-03-31 2011-01-11 Cardiac Pacemakers, Inc. Pacing therapy for diastolic heart failure
US7869885B2 (en) 2006-04-28 2011-01-11 Cyberonics, Inc Threshold optimization for tissue stimulation therapy
US8620430B2 (en) 2006-06-30 2013-12-31 Cardiac Pacemakers, Inc. Selection of pacing sites to enhance cardiac performance
US7955268B2 (en) 2006-07-21 2011-06-07 Cardiac Pacemakers, Inc. Multiple sensor deployment
US7869867B2 (en) 2006-10-27 2011-01-11 Cyberonics, Inc. Implantable neurostimulator with refractory stimulation
US8725255B2 (en) * 2006-11-17 2014-05-13 Cardiac Pacemakers, Inc. Cardiac resynchronization therapy optimization using cardiac activation sequence information
US8868183B2 (en) * 2006-12-21 2014-10-21 Cardiac Pacemakers, Inc. Method and apparatus to implement multiple parameter sets in an implantable device
US7974701B2 (en) 2007-04-27 2011-07-05 Cyberonics, Inc. Dosing limitation for an implantable medical device
EP2164562B1 (en) * 2007-06-29 2014-10-01 Cardiac Pacemakers, Inc. Endocardial pacing relating to conduction abnormalities
US8768466B2 (en) * 2007-10-12 2014-07-01 Cardiac Pacemakers, Inc. Method and apparatus to trend and optimize an implantable medical device using a patient management system
JP5211177B2 (en) 2008-02-11 2013-06-12 カーディアック ペースメイカーズ， インコーポレイテッド Hemodynamic monitoring method for rhythm discrimination in the heart
WO2009102640A1 (en) 2008-02-12 2009-08-20 Cardiac Pacemakers, Inc. Systems and methods for controlling wireless signal transfers between ultrasound-enabled medical devices
US8204603B2 (en) 2008-04-25 2012-06-19 Cyberonics, Inc. Blocking exogenous action potentials by an implantable medical device
JP2011519665A (en) 2008-05-08 2011-07-14 カーディアック ペースメイカーズ， インコーポレイテッド Atrioventricular delay time calculation system
EP2334230A1 (en) 2008-10-10 2011-06-22 Cardiac Pacemakers, Inc. Systems and methods for determining cardiac output using pulmonary artery pressure measurements
US8457747B2 (en) 2008-10-20 2013-06-04 Cyberonics, Inc. Neurostimulation with signal duration determined by a cardiac cycle
WO2010059291A1 (en) 2008-11-19 2010-05-27 Cardiac Pacemakers, Inc. Assessment of pulmonary vascular resistance via pulmonary artery pressure
US20100191304A1 (en) 2009-01-23 2010-07-29 Scott Timothy L Implantable Medical Device for Providing Chronic Condition Therapy and Acute Condition Therapy Using Vagus Nerve Stimulation
JP2010259628A (en) * 2009-05-07 2010-11-18 Olympus Corp Heart treatment apparatus
EP2437849B1 (en) * 2009-06-01 2017-02-22 Cardiac Pacemakers, Inc. System for decompensation detection and treatment based on patient hemodynamics
US8417336B2 (en) 2009-06-01 2013-04-09 Cardiac Pacemakers, Inc. System and method for pacing rate control utilizing patient hemodynamic status information
EP2471575B1 (en) 2010-12-29 2018-11-21 Sorin CRM SAS Active implantable medical device with auricular stimulation for the treatment of diastolic cardiac insufficiency
US8805500B2 (en) * 2011-03-15 2014-08-12 Medtronic, Inc. Atrial nerve stimulation with ventricular pacing
US9227069B2 (en) 2011-03-15 2016-01-05 Medtronic, Inc. Atrial nerve stimulation with ventricular pacing
US9161724B2 (en) * 2012-07-20 2015-10-20 Koninklijke Philips N.V. Multi-cardiac sound gated imaging and post-processing of imaging data based on cardiac sound
US9008769B2 (en) 2012-12-21 2015-04-14 Backbeat Medical, Inc. Methods and systems for lowering blood pressure through reduction of ventricle filling
US9370662B2 (en) 2013-12-19 2016-06-21 Backbeat Medical, Inc. Methods and systems for controlling blood pressure by controlling atrial pressure
WO2016061176A1 (en) * 2014-10-17 2016-04-21 Cardiac Pacemakers, Inc. System for optimizing multi-site pacing using heart sounds
WO2016061202A1 (en) 2014-10-17 2016-04-21 Cardiac Pacemakers, Inc. System for ambulatory optimization of multi-site pacing using heart sounds
US10342982B2 (en) 2015-09-11 2019-07-09 Backbeat Medical, Inc. Methods and systems for treating cardiac malfunction
US10485658B2 (en) 2016-04-22 2019-11-26 Backbeat Medical, Inc. Methods and systems for controlling blood pressure
EP3496808B1 (en) * 2016-08-11 2020-06-10 Cardiac Pacemakers, Inc. Diastolic endocardial accelerations for heart failure monitoring

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5334222A (en) * 1992-11-03 1994-08-02 Cardiac Pacemakers, Inc. Cardiac stimulating apparatus and method for heart failure therapy
US6280389B1 (en) * 1999-11-12 2001-08-28 Cardiac Pacemakers, Inc. Patient identification for the pacing therapy using LV-RV pressure loop
US20020151938A1 (en) * 2000-11-17 2002-10-17 Giorgio Corbucci Myocardial performance assessment

Family Cites Families (124)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3995623A (en) 1974-12-23 1976-12-07 American Hospital Supply Corporation Multipurpose flow-directed catheter
US4354497A (en) 1977-05-23 1982-10-19 Medtronic, Inc. Cardiac depolarization detection apparatus
US4432362A (en) 1980-05-27 1984-02-21 Cordis Corporation Atrial-based, atrial-ventricular sequential cardiac pacer
US4401119A (en) 1981-02-17 1983-08-30 Medtronic, Inc. Prolongation of timing intervals in response to ectopic heart beats in atrial and ventricular pacemakers
US4686987A (en) 1981-06-18 1987-08-18 Cardiac Pacemakers, Inc. Biomedical method and apparatus for controlling the administration of therapy to a patient in response to changes in physiologic demand
US4485813A (en) 1981-11-19 1984-12-04 Medtronic, Inc. Implantable dynamic pressure transducer system
CA1290813C (en) 1985-08-12 1991-10-15 Michael B. Sweeney Pacemaker for detecting and terminating a tachycardia
US4872459A (en) 1985-08-12 1989-10-10 Intermedics, Inc. Pacemaker for detecting and terminating a tachycardia
US4719921A (en) * 1985-08-28 1988-01-19 Raul Chirife Cardiac pacemaker adaptive to physiological requirements
US4674518A (en) 1985-09-06 1987-06-23 Cardiac Pacemakers, Inc. Method and apparatus for measuring ventricular volume
SE8702523D0 (en) 1987-06-17 1987-06-17 Siemens Elema Ab RATE RESPONSIVE PACEMAKER
US5163429A (en) * 1987-10-06 1992-11-17 Leonard Bloom Hemodynamically responsive system for treating a malfunctioning heart
US5014698A (en) 1987-10-06 1991-05-14 Leonard Bloom Method of and system for monitoring and treating a malfunctioning heart
US4928688A (en) 1989-01-23 1990-05-29 Mieczyslaw Mirowski Method and apparatus for treating hemodynamic disfunction
US4945909A (en) 1989-06-06 1990-08-07 Cook Pacemaker Corporation Pacemaker with activity-dependent rate limiting
US5318595A (en) * 1989-09-25 1994-06-07 Ferek Petric Bozidar Pacing method and system for blood flow velocity measurement and regulation of heart stimulating signals based on blood flow velocity
US5083563A (en) 1990-02-16 1992-01-28 Telectronics Pacing Systems, Inc. Implantable automatic and haemodynamically responsive cardioverting/defibrillating pacemaker
US5156149A (en) 1990-08-10 1992-10-20 Medtronic, Inc. Sensor for detecting cardiac depolarizations particularly adapted for use in a cardiac pacemaker
US5370665A (en) 1990-08-10 1994-12-06 Medtronic, Inc. Medical stimulator with multiple operational amplifier output stimulation circuits
US5233985A (en) 1990-08-10 1993-08-10 Medtronic, Inc. Cardiac pacemaker with operational amplifier output circuit
US5267560A (en) 1990-09-07 1993-12-07 Cohen Fred M Methods for control of the ventricular activation sequence
US5174289A (en) 1990-09-07 1992-12-29 Cohen Fred M Pacing systems and methods for control of the ventricular activation sequence
EP0474957A3 (en) 1990-09-11 1992-06-24 Bozidar Ferek-Petric Ultrasonic doppler synchronized cardiac electrotherapy device
US5179949A (en) * 1990-12-07 1993-01-19 Raul Chirife Cardiac pacemaker with automatic a-v programming for optimization of left heart a-v interval
US5129394A (en) 1991-01-07 1992-07-14 Medtronic, Inc. Method and apparatus for controlling heart rate in proportion to left ventricular pressure
US5158079A (en) 1991-02-25 1992-10-27 Incontrol, Inc. Implantable device for preventing tachyarrhythmias
US5188106A (en) * 1991-03-08 1993-02-23 Telectronics Pacing Systems, Inc. Method and apparatus for chronically monitoring the hemodynamic state of a patient using doppler ultrasound
WO1994008657A1 (en) 1992-10-20 1994-04-28 Noel Desmond Gray A heart pacemaker
US5168869A (en) 1991-06-17 1992-12-08 Raul Chirife Rate responsive pacemaker controlled by isovolumic contraction time
ATE142520T1 (en) * 1991-11-04 1996-09-15 Cardiac Pacemakers Inc IMPLANTABLE HEART MONITORING AND STIMULATION DEVICE FOR DIAGNOSIS AND THERAPY
US5324326A (en) 1991-11-25 1994-06-28 Telectronics Pacing Systems, Inc. Pressure sensing pacing lead
US5342404A (en) 1992-04-03 1994-08-30 Intermedics, Inc. Implantable medical interventional device
US5271395A (en) * 1992-04-17 1993-12-21 Medtronic, Inc. Method and apparatus for rate-responsive cardiac pacing
US5690689A (en) 1992-11-13 1997-11-25 Pacesetter, Inc. Dual-chamber implantable stimulation device having adaptive AV intervall and method for treating cardiomyopathy thereof
US5496362A (en) 1992-11-24 1996-03-05 Cardiac Pacemakers, Inc. Implantable conformal coil patch electrode with multiple conductive elements for cardioversion and defibrillation
US5330511A (en) 1993-01-19 1994-07-19 Vitatron Medical B.V. Dual chamber pacemaker with automatically optimized AV delay
US5372607A (en) 1993-06-23 1994-12-13 Medtronic, Inc. Method and apparatus for monitoring pacemaker intervals
US5628777A (en) 1993-07-14 1997-05-13 Pacesetter, Inc. Implantable leads incorporating cardiac wall acceleration sensors and method of fabrication
US5368040A (en) * 1993-08-02 1994-11-29 Medtronic, Inc. Apparatus and method for determining a plurality of hemodynamic variables from a single, chroniclaly implanted absolute pressure sensor
US5609612A (en) 1993-10-05 1997-03-11 Sorin Biomedica Cardio S.P.A. Device for determining myocardial function and corresponding procedure and method
JP3045642B2 (en) * 1994-01-25 2000-05-29 アロカ株式会社 Ultrasound diagnostic equipment
FR2718036B1 (en) 1994-04-05 1996-08-30 Ela Medical Sa Method for controlling a triple atrial pacemaker of the triple chamber type.
FR2718035B1 (en) 1994-04-05 1996-08-30 Ela Medical Sa Method for controlling a double atrial pacemaker of the triple chamber type programmable in fallback mode.
US5433205A (en) * 1994-04-08 1995-07-18 Visveshwara; Nadarasa Method of optimizing ventilation perfusion match
US5549650A (en) 1994-06-13 1996-08-27 Pacesetter, Inc. System and method for providing hemodynamically optimal pacing therapy
US5534016A (en) 1995-02-21 1996-07-09 Vitatron Medical, B.V. Dual chamber pacing system and method utilizing detection of ventricular fusion for adjustment of the atrial-ventricular delay as therapy for hypertrophic obstructive cardiomyopathy
US5626620A (en) 1995-02-21 1997-05-06 Medtronic, Inc. Dual chamber pacing system and method with continual adjustment of the AV escape interval so as to maintain optimized ventricular pacing for treating cardiomyopathy
US5527347A (en) 1995-02-21 1996-06-18 Medtronic, Inc. Dual chamber pacing system and method with automatic adjustment of the AV escape interval for treating cardiomyopathy
US5514163A (en) 1995-02-21 1996-05-07 Medtronic, Inc. Dual chamber pacing system and method with optimized adjustment of the AV escape interval for treating cardiomyopathy
US5554177A (en) 1995-03-27 1996-09-10 Medtronic, Inc. Method and apparatus to optimize pacing based on intensity of acoustic signal
US5716383A (en) 1996-02-28 1998-02-10 Medtronic, Inc. Dual chamber pacing system and method with continual adjustment of the AV escape interval so as to maintain optimized ventricular pacing for treating cardiomyopathy
US5626623A (en) 1996-04-30 1997-05-06 Medtronic, Inc. Method and apparatus for optimizing pacemaker AV delay
US5683429A (en) 1996-04-30 1997-11-04 Medtronic, Inc. Method and apparatus for cardiac pacing to prevent atrial fibrillation
US6311089B1 (en) 1996-05-14 2001-10-30 Pacesetter, Inc. Implantable stimulation device and method for determining ventricular and atrial sensitivity thresholds
US5728140A (en) 1996-06-17 1998-03-17 Cardiac Pacemakers, Inc. Method for evoking capture of left ventricle using transeptal pacing lead
US5797970A (en) 1996-09-04 1998-08-25 Medtronic, Inc. System, adaptor and method to provide medical electrical stimulation
US5824019A (en) 1996-10-11 1998-10-20 Medtronic, Inc. Pacing system with physiologically timed ventricular pacing
US5713930A (en) 1996-11-06 1998-02-03 Vitatron Medical, B.V. Dual chamber pacing system and method with control of AV interval
US5700283A (en) 1996-11-25 1997-12-23 Cardiac Pacemakers, Inc. Method and apparatus for pacing patients with severe congestive heart failure
US5755766A (en) 1997-01-24 1998-05-26 Cardiac Pacemakers, Inc. Open-ended intravenous cardiac lead
US5935160A (en) 1997-01-24 1999-08-10 Cardiac Pacemakers, Inc. Left ventricular access lead for heart failure pacing
DE19711058A1 (en) 1997-03-03 1998-09-10 Biotronik Mess & Therapieg Device for determining the AV conduction time
US5978707A (en) 1997-04-30 1999-11-02 Cardiac Pacemakers, Inc. Apparatus and method for treating ventricular tachyarrhythmias
US6112117A (en) 1997-05-06 2000-08-29 Cardiac Pacemakers, Inc. Method and apparatus for treating cardiac arrhythmia using electrogram features
WO1999010042A1 (en) 1997-08-27 1999-03-04 Pacesetter, Inc. Dual chamber implantable pacemaker having negative av/pv hysteresis and ectopic discrimination
US6198952B1 (en) 1998-10-30 2001-03-06 Medtronic, Inc. Multiple lens oxygen sensor for medical electrical lead
US5800471A (en) 1997-10-20 1998-09-01 Cardiac Pacemakers, Inc. Method for optimizing cardiac performance by determining the optimal pacing mode-AV delay from a transient heart rate signal for use in CHF, brady, and tachy/brady therapy devices
US6070100A (en) 1997-12-15 2000-05-30 Medtronic Inc. Pacing system for optimizing cardiac output and determining heart condition
US6314322B1 (en) * 1998-03-02 2001-11-06 Abiomed, Inc. System and method for treating dilated cardiomyopathy using end diastolic volume (EDV) sensing
WO1999058191A1 (en) 1998-05-08 1999-11-18 Cardiac Pacemakers, Inc. Cardiac pacing using adjustable atrio-ventricular delays
US6144880A (en) 1998-05-08 2000-11-07 Cardiac Pacemakers, Inc. Cardiac pacing using adjustable atrio-ventricular delays
US7110817B2 (en) 1998-05-08 2006-09-19 Cardiac Pacemakers, Inc. Method and apparatus for optimizing ventricular synchrony during DDD resynchronization therapy using adjustable atrio-ventricular delays
US7158830B2 (en) 1998-05-08 2007-01-02 Cardiac Pacemakers, Inc. Method and apparatus for optimizing stroke volume during DDD resynchronization therapy using adjustable atrio-ventricular delays
US6128534A (en) * 1998-06-16 2000-10-03 Pacesetter, Inc. Implantable cardiac stimulation device and method for varying pacing parameters to mimic circadian cycles
US7599736B2 (en) * 2001-07-23 2009-10-06 Dilorenzo Biomedical, Llc Method and apparatus for neuromodulation and physiologic modulation for the treatment of metabolic and neuropsychiatric disease
US6044298A (en) 1998-10-13 2000-03-28 Cardiac Pacemakers, Inc. Optimization of pacing parameters based on measurement of integrated acoustic noise
US6136021A (en) 1999-03-23 2000-10-24 Cardiac Pacemakers, Inc. Expandable electrode for coronary venous leads
US6108577A (en) 1999-04-26 2000-08-22 Cardiac Pacemakers, Inc. Method and apparatus for detecting changes in electrocardiogram signals
US6309350B1 (en) 1999-05-03 2001-10-30 Tricardia, L.L.C. Pressure/temperature/monitor device for heart implantation
US6285907B1 (en) * 1999-05-21 2001-09-04 Cardiac Pacemakers, Inc. System providing ventricular pacing and biventricular coordination
US6273856B1 (en) 1999-10-19 2001-08-14 Cardiac Pacemakers, Inc. Apparatus and methods for METS measurement by accelerometer and minute ventilation sensors
US6418346B1 (en) * 1999-12-14 2002-07-09 Medtronic, Inc. Apparatus and method for remote therapy and diagnosis in medical devices via interface systems
US6328699B1 (en) * 2000-01-11 2001-12-11 Cedars-Sinai Medical Center Permanently implantable system and method for detecting, diagnosing and treating congestive heart failure
US7483743B2 (en) * 2000-01-11 2009-01-27 Cedars-Sinai Medical Center System for detecting, diagnosing, and treating cardiovascular disease
US6507756B1 (en) 2000-04-03 2003-01-14 Medtronic, Inc. Dual chamber pacing system having time-adaptive AV delay
US6922592B2 (en) 2000-04-04 2005-07-26 Medtronic, Inc. Implantable medical device controlled by a non-invasive physiological data measurement device
US6640135B1 (en) 2000-04-06 2003-10-28 Cardiac Pacemakers, Inc. Apparatus and method for spatially and temporally distributing cardiac electrical stimulation
US6449510B1 (en) 2000-04-27 2002-09-10 Medtronic, Inc. Method and system for operating an implantable medical device
US6754532B1 (en) * 2000-04-28 2004-06-22 Medtronic, Inc. Coronary sinus flow regulated pacing
WO2001087410A2 (en) 2000-05-15 2001-11-22 Pacesetter, Inc. Cardiac stimulation devices and methods for measuring impedances associated with the left side of the heart
US6519495B1 (en) * 2000-08-15 2003-02-11 Cardiac Pacemakers, Inc. Rate-adaptive therapy with sensor cross-checking
US6839593B1 (en) * 2000-09-08 2005-01-04 Cardiac Pacemakers, Inc. Rate-adaptive therapy with automatic limiting of maximum pacing rate
US6398738B1 (en) 2000-09-25 2002-06-04 Millar Instruments, Inc. Method and apparatus for reconstructing a high fidelity pressure waveform with a balloon catheter
US6904315B2 (en) 2000-12-14 2005-06-07 Medtronic, Inc. Atrial aware VVI: a method for atrial synchronous ventricular (VDD/R) pacing using the subcutaneous electrode array and a standard pacing lead
US6480742B2 (en) 2000-12-26 2002-11-12 Cardiac Pacemakers, Inc. Pace counter isolation for cardiac resynchronization pacing
US6522921B2 (en) 2000-12-26 2003-02-18 Cardiac Pacemakers, Inc. System and method for eliminating cross-talk due to far-field signals
US6438421B1 (en) 2000-12-26 2002-08-20 Cardiac Pacemakers, Inc. Mode transition timing for synchronized pacing
US6512952B2 (en) 2000-12-26 2003-01-28 Cardiac Pacemakers, Inc. Method and apparatus for maintaining synchronized pacing
US6553258B2 (en) 2000-12-26 2003-04-22 Cardiac Pacemakers, Inc. System and method for managing refractory periods in a cardiac rhythm management device with biventricular sensing
US6430439B1 (en) 2000-12-26 2002-08-06 Cardiac Pacemakers, Inc. Method for collection of biventricular histograms
US6738667B2 (en) * 2000-12-28 2004-05-18 Medtronic, Inc. Implantable medical device for treating cardiac mechanical dysfunction by electrical stimulation
US6522923B1 (en) 2001-02-09 2003-02-18 Pacesetter, Inc. Methods, systems and devices for optimizing cardiac pacing parameters using evolutionary algorithms
US6597951B2 (en) 2001-03-16 2003-07-22 Cardiac Pacemakers, Inc. Automatic selection from multiple cardiac optimization protocols
US6580946B2 (en) 2001-04-26 2003-06-17 Medtronic, Inc. Pressure-modulated rate-responsive cardiac pacing
US6628988B2 (en) 2001-04-27 2003-09-30 Cardiac Pacemakers, Inc. Apparatus and method for reversal of myocardial remodeling with electrical stimulation
US6654637B2 (en) 2001-04-30 2003-11-25 Medtronic, Inc. Method and system for ventricular fusion prevention
SE0103513D0 (en) * 2001-10-22 2001-10-22 St Jude Medical Pacemaker
US6795732B2 (en) * 2001-10-30 2004-09-21 Medtronic, Inc. Implantable medical device employing sonomicrometer output signals for detection and measurement of cardiac mechanical function
US6980851B2 (en) * 2001-11-15 2005-12-27 Cardiac Pacemakers, Inc. Method and apparatus for determining changes in heart failure status
US6832113B2 (en) 2001-11-16 2004-12-14 Cardiac Pacemakers, Inc. Non-invasive method and apparatus for cardiac pacemaker pacing parameter optimization and monitoring of cardiac dysfunction
US6810284B1 (en) * 2001-11-21 2004-10-26 Pacesetter, Inc. Implantable cardiac stimulation system and method for monitoring diastolic function
US7127289B2 (en) 2001-12-05 2006-10-24 Cardiac Pacemakers, Inc. Cardiac resynchronization system employing mechanical measurement of cardiac walls
US6892095B2 (en) 2001-12-31 2005-05-10 Cardiac Pacemakers, Inc. Method and apparatus for monitoring left ventricular work or power
US6666826B2 (en) 2002-01-04 2003-12-23 Cardiac Pacemakers, Inc. Method and apparatus for measuring left ventricular pressure
US7024244B2 (en) * 2002-04-22 2006-04-04 Medtronic, Inc. Estimation of stroke volume cardiac output using an intracardiac pressure sensor
US7037266B2 (en) * 2002-04-25 2006-05-02 Medtronic, Inc. Ultrasound methods and implantable medical devices using same
US7041061B2 (en) 2002-07-19 2006-05-09 Cardiac Pacemakers, Inc. Method and apparatus for quantification of cardiac wall motion asynchrony
US7206634B2 (en) 2002-07-26 2007-04-17 Cardiac Pacemakers, Inc. Method and apparatus for optimizing cardiac pumping performance
US7013176B2 (en) 2003-01-28 2006-03-14 Cardiac Pacemakers, Inc. Method and apparatus for setting pacing parameters in cardiac resynchronization therapy
US7092759B2 (en) * 2003-07-30 2006-08-15 Medtronic, Inc. Method of optimizing cardiac resynchronization therapy using sensor signals of septal wall motion
EP1670547B1 (en) * 2003-08-18 2008-11-12 Cardiac Pacemakers, Inc. Patient monitoring system
US9002452B2 (en) 2003-11-07 2015-04-07 Cardiac Pacemakers, Inc. Electrical therapy for diastolic dysfunction
US7184835B2 (en) * 2003-12-12 2007-02-27 Cardiac Pacemakers, Inc. Method and apparatus for adjustable AVD programming using a table
US7869871B2 (en) * 2006-03-31 2011-01-11 Cardiac Pacemakers, Inc. Pacing therapy for diastolic heart failure

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5334222A (en) * 1992-11-03 1994-08-02 Cardiac Pacemakers, Inc. Cardiac stimulating apparatus and method for heart failure therapy
US6280389B1 (en) * 1999-11-12 2001-08-28 Cardiac Pacemakers, Inc. Patient identification for the pacing therapy using LV-RV pressure loop
US20020151938A1 (en) * 2000-11-17 2002-10-17 Giorgio Corbucci Myocardial performance assessment

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ATE516850T1 (en) 2011-08-15
EP1680179A2 (en) 2006-07-19
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US9002452B2 (en) 2015-04-07

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