WO2005046791A3 - Tissue positioning systems and methods for use with radiation therapy - Google Patents

Tissue positioning systems and methods for use with radiation therapy Download PDF

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Publication number
WO2005046791A3
WO2005046791A3 PCT/US2004/037202 US2004037202W WO2005046791A3 WO 2005046791 A3 WO2005046791 A3 WO 2005046791A3 US 2004037202 W US2004037202 W US 2004037202W WO 2005046791 A3 WO2005046791 A3 WO 2005046791A3
Authority
WO
WIPO (PCT)
Prior art keywords
tissue
surface element
resected
cavity
expandable surface
Prior art date
Application number
PCT/US2004/037202
Other languages
French (fr)
Other versions
WO2005046791A2 (en
Inventor
Timothy J Patrick
James B Stubbs
Original Assignee
Cytyc Corp
Timothy J Patrick
James B Stubbs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytyc Corp, Timothy J Patrick, James B Stubbs filed Critical Cytyc Corp
Priority to AU2004289268A priority Critical patent/AU2004289268B2/en
Priority to CN2004800398511A priority patent/CN1929891B/en
Priority to EP04800876A priority patent/EP1689491A2/en
Priority to BRPI0416242-0A priority patent/BRPI0416242A/en
Priority to JP2006539711A priority patent/JP4880475B2/en
Priority to CA002544756A priority patent/CA2544756A1/en
Publication of WO2005046791A2 publication Critical patent/WO2005046791A2/en
Priority to IL175386A priority patent/IL175386A0/en
Publication of WO2005046791A3 publication Critical patent/WO2005046791A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1014Intracavitary radiation therapy
    • A61N5/1015Treatment of resected cavities created by surgery, e.g. lumpectomy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1049Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam

Abstract

A system for treating tissue surrounding a resected cavity that is subject to a proliferative tissue disorder is provided. The system includes a tissue fixation device including a catheter body member having a proximal end, a distal end, an inner lumen, and an expandable surface element disposed proximate to the distal end of the body member, the expandable surface element sized and configured to reproducibly position tissue surrounding a resected tissue cavity in a predetermined geometry upon expansion. After expansion of the expandable surface element within a resected tissue cavity, an external radiation device positioned outside the resected cavity delivers a dose of radiation to the tissue surrounding the expandable surface element.
PCT/US2004/037202 2003-11-07 2004-11-05 Tissue positioning systems and methods for use with radiation therapy WO2005046791A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
AU2004289268A AU2004289268B2 (en) 2003-11-07 2004-11-05 Tissue positioning systems and methods for use with radiation therapy
CN2004800398511A CN1929891B (en) 2003-11-07 2004-11-05 Tissue positioning systems and methods for use with radiation therapy
EP04800876A EP1689491A2 (en) 2003-11-07 2004-11-05 Tissue positioning systems and methods for use with radiation therapy
BRPI0416242-0A BRPI0416242A (en) 2003-11-07 2004-11-05 method for treating a proliferative tissue disorder, system for treating tissue surrounding a resected cavity, and device for treating a proliferative tissue disorder following a lumpectomy procedure
JP2006539711A JP4880475B2 (en) 2003-11-07 2004-11-05 System for treating tissue around a resected cavity that may be affected by proliferative tissue damage and apparatus for treating proliferative tissue damage after a mammary mass removal procedure
CA002544756A CA2544756A1 (en) 2003-11-07 2004-11-05 Tissue positioning systems and methods for use with radiation therapy
IL175386A IL175386A0 (en) 2003-11-07 2006-05-02 Tissue positioning systems and methods for use with radiation therapy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/704,161 US7524274B2 (en) 2003-11-07 2003-11-07 Tissue positioning systems and methods for use with radiation therapy
US10/704,161 2003-11-07

Publications (2)

Publication Number Publication Date
WO2005046791A2 WO2005046791A2 (en) 2005-05-26
WO2005046791A3 true WO2005046791A3 (en) 2006-11-16

Family

ID=34552060

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/037202 WO2005046791A2 (en) 2003-11-07 2004-11-05 Tissue positioning systems and methods for use with radiation therapy

Country Status (10)

Country Link
US (1) US7524274B2 (en)
EP (1) EP1689491A2 (en)
JP (1) JP4880475B2 (en)
KR (1) KR20070011235A (en)
CN (1) CN1929891B (en)
AU (1) AU2004289268B2 (en)
BR (1) BRPI0416242A (en)
CA (1) CA2544756A1 (en)
IL (1) IL175386A0 (en)
WO (1) WO2005046791A2 (en)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8288745B2 (en) * 1997-10-10 2012-10-16 Senorx, Inc. Method of utilizing an implant for targeting external beam radiation
DE60324448D1 (en) 2002-09-10 2008-12-11 Cianna Medical Inc brachytherapy
GB2415907A (en) * 2004-07-05 2006-01-11 Vishnu Shanker Shukla A radiotherapy device for treating cancers in viscous organs such as the bladder
WO2006039698A1 (en) * 2004-10-01 2006-04-13 Calypso Medical Technologies, Inc. Systems and methods for treating a patient using radiation therapy
US7662082B2 (en) 2004-11-05 2010-02-16 Theragenics Corporation Expandable brachytherapy device
JP2009504269A (en) * 2005-08-08 2009-02-05 サイティック コーポレーション How to inflate and space the skin
US9498647B2 (en) * 2005-09-23 2016-11-22 Allen B. Kantrowitz Fiducial marker system for subject movement compensation during medical treatment
WO2007053823A2 (en) 2005-10-31 2007-05-10 Biolucent, Inc. Brachytherapy apparatus and methods of using same
US7862496B2 (en) 2005-11-10 2011-01-04 Cianna Medical, Inc. Brachytherapy apparatus and methods for using them
US7887476B2 (en) 2005-11-10 2011-02-15 Cianna Medical, Inc. Helical brachytherapy apparatus and methods of using same
US8137256B2 (en) * 2005-12-16 2012-03-20 Portola Medical, Inc. Brachytherapy apparatus
US20070270627A1 (en) 2005-12-16 2007-11-22 North American Scientific Brachytherapy apparatus for asymmetrical body cavities
US9072893B2 (en) 2006-06-02 2015-07-07 Cianna Medical, Inc. Expandable brachytherapy apparatus and methods for using them
WO2008033728A2 (en) * 2006-09-11 2008-03-20 Pluromed, Inc. Atraumatic occlusion balloons and skirts, and methods of use thereof
AU2007307854B2 (en) 2006-10-08 2012-01-19 Cianna Medical, Inc. Expandable brachytherapy apparatus
US7727137B2 (en) 2006-10-13 2010-06-01 Xoft, Inc. Balloon brachytherapy applicator and method
WO2008058089A2 (en) * 2006-11-03 2008-05-15 North American Scientific, Inc. Brachytherapy device having seed tubes with individually-settable tissue spacings
US20080177179A1 (en) * 2006-12-19 2008-07-24 Cytyc Corporation Target Tissue Locator for Image Guided Radiotherapy
AU2008224435B2 (en) 2007-03-15 2014-01-09 Ortho-Space Ltd. Prosthetic devices and methods for using same
US20090024225A1 (en) * 2007-07-16 2009-01-22 Stubbs James B Implant for Targeting Therapeutic Procedure
US7771340B2 (en) * 2007-07-28 2010-08-10 Xoft, Inc. Method and apparatus for modifying distance from a brachytherapy radiation source to sensitive anatomical structures
WO2009053897A1 (en) * 2007-10-26 2009-04-30 Koninklijke Philips Electronics, N.V. Electromagnetic pose sensing of hdr brachytherapy applicator
US8517907B2 (en) 2007-12-16 2013-08-27 Cianna Medical, Inc. Expandable brachytherapy apparatus and methods for using them
US8636635B2 (en) 2008-08-18 2014-01-28 Cianna Medical, Inc. Brachytherapy apparatus, systems, and methods for using them
US9014787B2 (en) * 2009-06-01 2015-04-21 Focal Therapeutics, Inc. Bioabsorbable target for diagnostic or therapeutic procedure
US8828040B2 (en) * 2009-07-07 2014-09-09 Thomas G. Goff Device and methods for delivery and transfer of temporary radiopaque element
US9089314B2 (en) * 2010-01-27 2015-07-28 Medtronic Cryocath Lp Partially compliant balloon device
US8814775B2 (en) 2010-03-18 2014-08-26 Cianna Medical, Inc. Expandable brachytherapy apparatus and methods for using them
US8706198B2 (en) * 2010-07-06 2014-04-22 Quali-Med Gmbh Opacity technology
US9883919B2 (en) 2010-07-21 2018-02-06 Cianna Medical, Inc. Brachytherapy apparatus, systems, and methods for using them
WO2012017438A1 (en) 2010-08-04 2012-02-09 Ortho-Space Ltd. Shoulder implant
WO2012045163A1 (en) * 2010-10-06 2012-04-12 University Health Network Methods and systems for automated planning of radiation therapy
US9067063B2 (en) 2010-11-03 2015-06-30 Cianna Medical, Inc. Expandable brachytherapy apparatus and methods for using them
US20140200489A1 (en) * 2011-09-01 2014-07-17 Perseus-Biomed Inc Method and system for tissue modulation
WO2013057566A2 (en) 2011-10-18 2013-04-25 Ortho-Space Ltd. Prosthetic devices and methods for using same
US9320517B2 (en) 2012-01-12 2016-04-26 Surgical Radiation Products, Llc Targeting implant for external beam radiation
US9943706B2 (en) 2012-01-12 2018-04-17 Surgical Radiation Products, Llc Targeting implant for external beam radiation
US9421349B2 (en) * 2012-01-12 2016-08-23 Stuart H. Miller Angioplasty pressure transducer
US20130289389A1 (en) 2012-04-26 2013-10-31 Focal Therapeutics Surgical implant for marking soft tissue
WO2014039724A1 (en) * 2012-09-06 2014-03-13 Covidien Lp Neurological treatment system
CN106659868B (en) * 2014-06-24 2019-11-29 普罗赛普特生物机器人公司 Sample of tissue and cancer treatment facilities
JP6702635B2 (en) 2014-07-25 2020-06-03 フォーカル セラピューティクス,インコーポレイテッド Implantable devices and techniques for oncoplastic surgery
US11219502B2 (en) 2017-09-11 2022-01-11 Medtronic Advanced Energy, Llc Transformative shape-memory polymer tissue cavity marker devices, systems and deployment methods
US20190117971A1 (en) * 2017-10-23 2019-04-25 Cardiac Pacemakers, Inc. Volume-filling leads for treatment of cancer with electric fields
US11324567B2 (en) 2018-02-01 2022-05-10 Medtronic Advanced Energy, Llc Expandable tissue cavity marker devices, systems and deployment methods
WO2020029089A1 (en) * 2018-08-07 2020-02-13 西安大医集团有限公司 Method and device for position adjustment, and radiotherapy system
DE102018216760A1 (en) * 2018-09-28 2020-04-02 Carl Zeiss Meditec Ag Applicator for intraoperative radiation therapy
CN109331349B (en) * 2018-11-20 2021-03-09 北京大学第一医院 Filling device for radiotherapy tracing after breast protection
CN113727753A (en) 2019-04-22 2021-11-30 波士顿科学国际有限公司 Electrical stimulation device for cancer treatment
WO2020219517A2 (en) 2019-04-23 2020-10-29 Boston Scientific Scimed, Inc. Electrical stimulation for cancer treatment with internal and external electrodes
CN113747936A (en) 2019-04-23 2021-12-03 波士顿科学国际有限公司 Electrode for electrical stimulation to treat cancer
US11712561B2 (en) 2019-04-23 2023-08-01 Boston Scientific Scimed, Inc. Electrical stimulation with thermal treatment or thermal monitoring
DE102019126326B3 (en) 2019-09-30 2021-01-28 Carl Zeiss Meditec Ag Brachytherapy device
CN115515674A (en) 2020-02-24 2022-12-23 波士顿科学国际有限公司 Systems and methods for treating pancreatic cancer

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000022904A2 (en) * 2000-02-02 2000-04-27 Northern Digital Inc. Device for determining the position of body parts and use of the same
US6200257B1 (en) * 1999-03-24 2001-03-13 Proxima Therapeutics, Inc. Catheter with permeable hydrogel membrane
US6413204B1 (en) * 1997-07-24 2002-07-02 Proxima Therapeutics, Inc. Interstitial brachytherapy apparatus and method for treatment of proliferative tissue diseases
US20030028097A1 (en) * 2001-08-03 2003-02-06 D'amico Anthony V. Immobilizer probe system and method

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3324847A (en) * 1964-06-01 1967-06-13 Elias G Zoumboulis Radioactive catheter
US3872856A (en) * 1971-06-09 1975-03-25 Ralph S Clayton Apparatus for treating the walls and floor of the pelvic cavity with radiation
JPS5878654A (en) 1981-09-04 1983-05-12 オクシメトリツクス・インコ−ポレ−テツド Medical apparatus for localizing treatment
US4417576A (en) * 1982-02-25 1983-11-29 Baran Ostap E Double-wall surgical cuff
US4867741A (en) * 1983-11-04 1989-09-19 Portnoy Harold D Physiological draining system with differential pressure and compensating valves
NL8400108A (en) 1984-01-12 1985-08-01 Hooft Eric T METHOD AND APPARATUS FOR TREATING A BODY PART WITH RADIOACTIVE MATERIAL
US4754745A (en) * 1984-11-21 1988-07-05 Horowitz Bruce S Conformable sheet material for use in brachytherapy
FR2582947B1 (en) * 1985-06-07 1988-05-13 Cgr Mev HYPERTHERMIA TREATMENT DEVICE
US4706652A (en) * 1985-12-30 1987-11-17 Henry Ford Hospital Temporary radiation therapy
US4763642A (en) * 1986-04-07 1988-08-16 Horowitz Bruce S Intracavitational brachytherapy
NL8601808A (en) * 1986-07-10 1988-02-01 Hooft Eric T METHOD FOR TREATING A BODY PART WITH RADIOACTIVE MATERIAL AND CART USED THEREIN
JPS6446056U (en) * 1987-09-17 1989-03-22
US5084015A (en) * 1988-05-16 1992-01-28 Terumo Kabushiki Kaisha Catheter assembly of the hypodermic embedment type
US5030195A (en) * 1989-06-05 1991-07-09 Nardi George L Radioactive seed patch for prophylactic therapy
DE3927001A1 (en) * 1989-08-16 1991-02-21 Lucien C Dr Med Olivier CATHETER SYSTEM
US5236410A (en) * 1990-08-02 1993-08-17 Ferrotherm International, Inc. Tumor treatment method
WO1992010932A1 (en) 1990-12-17 1992-07-09 Microwave Medical Systems, Inc. Therapeutic probe for radiating microwave and nuclear radiation
US5484384A (en) * 1991-01-29 1996-01-16 Med Institute, Inc. Minimally invasive medical device for providing a radiation treatment
US5112303A (en) * 1991-05-02 1992-05-12 Pudenz-Schulte Medical Research Corporation Tumor access device and method for delivering medication into a body cavity
US5429582A (en) * 1991-06-14 1995-07-04 Williams; Jeffery A. Tumor treatment
IT1251997B (en) 1991-11-11 1995-05-27 San Romanello Centro Fond RADIANT DEVICE FOR HYPERTHERMIA
US6217503B1 (en) 1994-01-21 2001-04-17 The Trustees Of Columbia University In The City Of New York Apparatus and method to treat a disease process in a luminal structure
US5503613A (en) * 1994-01-21 1996-04-02 The Trustees Of Columbia University In The City Of New York Apparatus and method to reduce restenosis after arterial intervention
US5707332A (en) * 1994-01-21 1998-01-13 The Trustees Of Columbia University In The City Of New York Apparatus and method to reduce restenosis after arterial intervention
US6120523A (en) * 1994-02-24 2000-09-19 Radiance Medical Systems, Inc. Focalized intraluminal balloons
US5750717A (en) * 1994-03-02 1998-05-12 Daicel Chemical Industries, Ltd. 2-isoxazoline derivative and process for producing the same, and process for producing related derivatives from the same
US5566221A (en) * 1994-07-12 1996-10-15 Photoelectron Corporation Apparatus for applying a predetermined x-radiation flux to an interior surface of a body cavity
US5616114A (en) * 1994-12-08 1997-04-01 Neocardia, Llc. Intravascular radiotherapy employing a liquid-suspended source
US5653683A (en) 1995-02-28 1997-08-05 D'andrea; Mark A. Intracavitary catheter for use in therapeutic radiation procedures
US5713828A (en) * 1995-11-27 1998-02-03 International Brachytherapy S.A Hollow-tube brachytherapy device
US5785688A (en) * 1996-05-07 1998-07-28 Ceramatec, Inc. Fluid delivery apparatus and method
US5924973A (en) 1996-09-26 1999-07-20 The Trustees Of Columbia University In The City Of New York Method of treating a disease process in a luminal structure
US5764723A (en) * 1996-10-16 1998-06-09 The Trustees Of Columbia University In The City Of New York Apparatus and method to gate a source for radiation therapy
US6261320B1 (en) * 1996-11-21 2001-07-17 Radiance Medical Systems, Inc. Radioactive vascular liner
US5782742A (en) * 1997-01-31 1998-07-21 Cardiovascular Dynamics, Inc. Radiation delivery balloon
US6458069B1 (en) * 1998-02-19 2002-10-01 Endology, Inc. Multi layer radiation delivery balloon
US6287249B1 (en) * 1998-02-19 2001-09-11 Radiance Medical Systems, Inc. Thin film radiation source
SE511291C2 (en) * 1997-03-18 1999-09-06 Anders Widmark Procedure, arrangement and reference organ for radiation therapy
US6033357A (en) 1997-03-28 2000-03-07 Navius Corporation Intravascular radiation delivery device
US5993374A (en) * 1997-06-17 1999-11-30 Radiance Medical Systems, Inc. Microcapsules for site-specific delivery
AT407009B (en) 1997-09-01 2000-11-27 Ali Dr Hassan CATHETER DEVICE FOR RADIOACTIVE TREATMENT OF BODY CAVES
US6471630B1 (en) * 1998-03-24 2002-10-29 Radiomed Corporation Transmutable radiotherapy device
US6048299A (en) * 1997-11-07 2000-04-11 Radiance Medical Systems, Inc. Radiation delivery catheter
US6149574A (en) * 1997-12-19 2000-11-21 Radiance Medical Systems, Inc. Dual catheter radiation delivery system
JP2001526946A (en) 1997-12-31 2001-12-25 クック インコーポレイティド Radioactive gas injection device
US6036631A (en) * 1998-03-09 2000-03-14 Urologix, Inc. Device and method for intracavitary cancer treatment
US6066856A (en) * 1998-05-18 2000-05-23 Children's Medical Center Corporation Radiation protective device
US6419692B1 (en) * 1999-02-03 2002-07-16 Scimed Life Systems, Inc. Surface protection method for stents and balloon catheters for drug delivery
US6746465B2 (en) 2001-12-14 2004-06-08 The Regents Of The University Of California Catheter based balloon for therapy modification and positioning of tissue

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6413204B1 (en) * 1997-07-24 2002-07-02 Proxima Therapeutics, Inc. Interstitial brachytherapy apparatus and method for treatment of proliferative tissue diseases
US6200257B1 (en) * 1999-03-24 2001-03-13 Proxima Therapeutics, Inc. Catheter with permeable hydrogel membrane
WO2000022904A2 (en) * 2000-02-02 2000-04-27 Northern Digital Inc. Device for determining the position of body parts and use of the same
US20030028097A1 (en) * 2001-08-03 2003-02-06 D'amico Anthony V. Immobilizer probe system and method

Also Published As

Publication number Publication date
AU2004289268A1 (en) 2005-05-26
WO2005046791A2 (en) 2005-05-26
US20050101860A1 (en) 2005-05-12
IL175386A0 (en) 2006-09-05
EP1689491A2 (en) 2006-08-16
JP2007510512A (en) 2007-04-26
AU2004289268B2 (en) 2010-12-16
BRPI0416242A (en) 2007-01-09
CN1929891A (en) 2007-03-14
KR20070011235A (en) 2007-01-24
CN1929891B (en) 2010-10-13
US7524274B2 (en) 2009-04-28
CA2544756A1 (en) 2005-05-26
JP4880475B2 (en) 2012-02-22

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