WO2005076796A3 - Systems and methods for calibrating osmolarity measuring devices - Google Patents

Systems and methods for calibrating osmolarity measuring devices Download PDF

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Publication number
WO2005076796A3
WO2005076796A3 PCT/US2005/001573 US2005001573W WO2005076796A3 WO 2005076796 A3 WO2005076796 A3 WO 2005076796A3 US 2005001573 W US2005001573 W US 2005001573W WO 2005076796 A3 WO2005076796 A3 WO 2005076796A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
osmolarity
calibrating
systems
measuring devices
Prior art date
Application number
PCT/US2005/001573
Other languages
French (fr)
Other versions
WO2005076796A2 (en
Inventor
Benjamin Sullivan
Eric Donsky
Original Assignee
Ocusense Inc
Benjamin Sullivan
Eric Donsky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ocusense Inc, Benjamin Sullivan, Eric Donsky filed Critical Ocusense Inc
Priority to EP05711596A priority Critical patent/EP1711797A4/en
Priority to JP2006551205A priority patent/JP4782020B2/en
Publication of WO2005076796A2 publication Critical patent/WO2005076796A2/en
Publication of WO2005076796A3 publication Critical patent/WO2005076796A3/en

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N13/00Investigating surface or boundary effects, e.g. wetting power; Investigating diffusion effects; Analysing materials by determining surface, boundary, or diffusion effects
    • G01N13/04Investigating osmotic effects

Abstract

An osmolarity measuring system comprising micro scale electrode arrays is configured to account for variations and defects in the arrays using a tiered approach comprising several calibration methods. One method accounts for the intrinsic conductivity of the electrodes and subtracts out the intrinsic conductivity on a pair-wise basis, when determining osmolarity of a sample fluid. Other methods in the tiered approach use standards to determine calibration factors for the electrodes that can then be used to adjust subsequent osmolarity measurements for a sample fluid. The use of a standard can also be combined with a washing step.
PCT/US2005/001573 2004-02-03 2005-01-21 Systems and methods for calibrating osmolarity measuring devices WO2005076796A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP05711596A EP1711797A4 (en) 2004-02-03 2005-01-21 Systems and methods for calibrating osmolarity measuring devices
JP2006551205A JP4782020B2 (en) 2004-02-03 2005-01-21 System and method for calibrating an osmotic pressure measuring device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/772,084 2004-02-03
US10/772,084 US7051569B2 (en) 2002-08-06 2004-02-03 Systems and methods for calibrating osmolarity measuring devices

Publications (2)

Publication Number Publication Date
WO2005076796A2 WO2005076796A2 (en) 2005-08-25
WO2005076796A3 true WO2005076796A3 (en) 2006-05-11

Family

ID=34860778

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/001573 WO2005076796A2 (en) 2004-02-03 2005-01-21 Systems and methods for calibrating osmolarity measuring devices

Country Status (4)

Country Link
US (2) US7051569B2 (en)
EP (1) EP1711797A4 (en)
JP (1) JP4782020B2 (en)
WO (1) WO2005076796A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8020433B2 (en) 2003-03-25 2011-09-20 Tearlab Research, Inc. Systems and methods for a sample fluid collection device
US8627712B2 (en) 2006-12-11 2014-01-14 Tearlab Research, Inc. Systems and methods for collecting tear film and measuring tear film osmolarity

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US7905134B2 (en) * 2002-08-06 2011-03-15 The Regents Of The University Of California Biomarker normalization
US7472576B1 (en) * 2004-11-17 2009-01-06 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Portland State University Nanometrology device standards for scanning probe microscopes and processes for their fabrication and use
JP2006223501A (en) * 2005-02-17 2006-08-31 Japan Health Science Foundation Biological fluid osmotic pressure sensor
US8173071B2 (en) 2006-08-29 2012-05-08 International Business Machines Corporation Micro-fluidic test apparatus and method
US7908906B2 (en) * 2006-08-29 2011-03-22 International Business Machines Corporation Fluidic test apparatus and method
AU2008240036B2 (en) * 2007-04-16 2013-11-28 The Regents Of The University Of California Biomarker normalization
AU2014201103B2 (en) * 2007-04-16 2014-10-23 The Regents Of The University Of California Biomarker normalization
WO2009032553A2 (en) * 2007-08-31 2009-03-12 Leon Dejournett Catheter and computerized system for intravenous blood chemistry monitoring
JP5558902B2 (en) * 2010-04-28 2014-07-23 日立コンシューマエレクトロニクス株式会社 Motor function analyzer
GB201202387D0 (en) 2012-02-13 2012-03-28 Nachum Zvi Device for in-vivo determination of eye moisture
ES2828278T3 (en) 2014-09-23 2021-05-25 Tearlab Res Inc Microfluidic tear collection integration system and lateral flow analysis of analytes of interest
WO2017195861A1 (en) * 2016-05-13 2017-11-16 国立研究開発法人物質・材料研究機構 Droplet size determining device and droplet size determining method
CN112485301B (en) * 2020-11-25 2023-07-14 三诺生物传感股份有限公司 Test method, system, equipment and medium of electrochemical test device

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US20040036485A1 (en) * 2002-08-06 2004-02-26 Sullivan Benjamin D. Tear film osmometry

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JPH0689954B2 (en) * 1986-10-09 1994-11-14 株式会社日立製作所 Cryogenic cooling unit structure
US4996993A (en) * 1988-12-07 1991-03-05 York Kenneth K In vivo osmometer
US4951683A (en) 1989-01-19 1990-08-28 Davis Jeffrey P Device for detecting keratoconjunctivitis sicca
JP3166471B2 (en) * 1994-02-28 2001-05-14 株式会社島津製作所 Conductivity measurement method
US6886421B2 (en) * 1997-07-21 2005-05-03 Vijay Mathur Modular film sensors with record memory for modular automated diagnostic apparatus
US7021122B1 (en) * 1998-03-19 2006-04-04 Orgenics Biosensors Ltd. Device for the determination of blood clotting by capacitance or resistance
US6558945B1 (en) * 1999-03-08 2003-05-06 Aclara Biosciences, Inc. Method and device for rapid color detection
WO2002012129A1 (en) * 2000-08-07 2002-02-14 Sievers Instruments, Inc. Low-level boron detection and measurement

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5132012A (en) * 1988-06-24 1992-07-21 Hitachi, Ltd. Liquid chromatograph
US5571568A (en) * 1989-06-15 1996-11-05 Biocircuits Corporation Multilayered bioelectronic sensors
US5851489A (en) * 1994-05-17 1998-12-22 Micronas Intermetall Gmbh Specimen slide for a microscope
US20040036485A1 (en) * 2002-08-06 2004-02-26 Sullivan Benjamin D. Tear film osmometry

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1711797A4 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8020433B2 (en) 2003-03-25 2011-09-20 Tearlab Research, Inc. Systems and methods for a sample fluid collection device
US8628731B2 (en) 2003-03-25 2014-01-14 Tearlab Research, Inc. Systems and methods for collecting tear film and measuring tear film osmolarity
US8713997B2 (en) 2003-03-25 2014-05-06 Tearlab Research, Inc. Systems and methods for collecting tear film and measuring tear film osmolarity
US8627712B2 (en) 2006-12-11 2014-01-14 Tearlab Research, Inc. Systems and methods for collecting tear film and measuring tear film osmolarity
US9335243B2 (en) 2006-12-11 2016-05-10 Tearlab Research, Inc. Systems and methods for collecting tear film and measuring tear film osmolarity

Also Published As

Publication number Publication date
US20050120772A1 (en) 2005-06-09
US7051569B2 (en) 2006-05-30
US20060107729A1 (en) 2006-05-25
EP1711797A1 (en) 2006-10-18
EP1711797A4 (en) 2011-02-09
JP2007520709A (en) 2007-07-26
JP4782020B2 (en) 2011-09-28
US7204122B2 (en) 2007-04-17
WO2005076796A2 (en) 2005-08-25

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