WO2005119255A3 - Constrained cis-diol-borate bioconjugation system - Google Patents

Constrained cis-diol-borate bioconjugation system Download PDF

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Publication number
WO2005119255A3
WO2005119255A3 PCT/US2005/016508 US2005016508W WO2005119255A3 WO 2005119255 A3 WO2005119255 A3 WO 2005119255A3 US 2005016508 W US2005016508 W US 2005016508W WO 2005119255 A3 WO2005119255 A3 WO 2005119255A3
Authority
WO
WIPO (PCT)
Prior art keywords
borate
diol
bioconjugation
cis
constrained cis
Prior art date
Application number
PCT/US2005/016508
Other languages
French (fr)
Other versions
WO2005119255A2 (en
Inventor
Ricky F Baggio
Alison L Sparks
Rouh-Rong Juo
Jaime F Arenas
Original Assignee
Applera Corp
Ricky F Baggio
Alison L Sparks
Rouh-Rong Juo
Jaime F Arenas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applera Corp, Ricky F Baggio, Alison L Sparks, Rouh-Rong Juo, Jaime F Arenas filed Critical Applera Corp
Publication of WO2005119255A2 publication Critical patent/WO2005119255A2/en
Publication of WO2005119255A3 publication Critical patent/WO2005119255A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier

Abstract

The invention pertains to bioconjugation systems comprising sterically constrained cis-diols and borates.
PCT/US2005/016508 2004-05-12 2005-05-11 Constrained cis-diol-borate bioconjugation system WO2005119255A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US57031304P 2004-05-12 2004-05-12
US60/570,313 2004-05-12
US57894604P 2004-06-10 2004-06-10
US60/578,946 2004-06-10

Publications (2)

Publication Number Publication Date
WO2005119255A2 WO2005119255A2 (en) 2005-12-15
WO2005119255A3 true WO2005119255A3 (en) 2007-03-01

Family

ID=35463521

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/016508 WO2005119255A2 (en) 2004-05-12 2005-05-11 Constrained cis-diol-borate bioconjugation system

Country Status (2)

Country Link
US (2) US7399645B2 (en)
WO (1) WO2005119255A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005119255A2 (en) * 2004-05-12 2005-12-15 Applera Corporation Constrained cis-diol-borate bioconjugation system
CN102123698B (en) 2008-08-13 2016-06-22 加利福尼亚技术学院 Carrier nanoparticles and relevant compositions, method and system
US20130001137A1 (en) * 2010-01-28 2013-01-03 Mcmaster University Nanoparticle flotation collectors
CN105189614B (en) * 2013-03-01 2019-04-12 加州理工学院 With the nanoparticle that nitrobenzene boronic acid composition is stable
US9468681B2 (en) 2013-03-01 2016-10-18 California Institute Of Technology Targeted nanoparticles
US11754563B2 (en) * 2014-11-20 2023-09-12 Global Life Sciences Solutions Operations UK Ltd Porous membranes with a polymer grafting, methods and uses thereof
WO2017003668A1 (en) 2015-07-01 2017-01-05 California Institute Of Technology Cationic mucic acid polymer-based delivery systems
US10906033B2 (en) 2016-03-28 2021-02-02 Kansas State University Research Foundation Synthesis and application of chiral substituted polyvinylpyrrolidinones
JP2018058868A (en) * 2017-11-24 2018-04-12 カリフォルニア インスティテュート オブ テクノロジー Nanoparticles stabilized with nitrophenylboronic acid compositions
JP2019108372A (en) * 2019-03-04 2019-07-04 カリフォルニア インスティテュート オブ テクノロジー Nanoparticles stabilized with nitrophenylboronic acid compositions
CN111440215B (en) * 2020-05-18 2021-08-20 南京工业大学 Method for preparing Reidesvir by using microchannel reaction device
CN114460310A (en) * 2022-04-12 2022-05-10 天津康博尔生物基因技术有限公司 Colored latex microsphere and preparation method and application thereof
CN114958748B (en) * 2022-04-24 2024-02-13 东北大学 Nanometer magnetic affinity material for efficiently capturing and nondestructively releasing circulating tumor cells

Citations (5)

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Publication number Priority date Publication date Assignee Title
EP0295073A2 (en) * 1987-06-08 1988-12-14 Chromatochem, Inc. Chromatographic material
WO2000012540A1 (en) * 1998-08-28 2000-03-09 Eli Lilly And Company Reversible boronate complexes of 1,2-cis-diol cyclic-peptides
US20030073243A1 (en) * 2001-08-31 2003-04-17 Law Wai Tak Method for quantitative determination of glycated hemoglobin
WO2003102217A2 (en) * 2002-06-03 2003-12-11 Dow Corning Corporation Synthesis of cis-diols from aryl silanes
WO2005016859A2 (en) * 2003-08-14 2005-02-24 Cephalon, Inc. Proteasome inhibitors and methods of using the same

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
US5227474A (en) * 1987-02-13 1993-07-13 Abbott Laboratories Bifunctional chelating agents
US5847192A (en) * 1994-01-28 1998-12-08 Prolinx, Inc. Boronic compound complexing reagents and complexes
US5744627A (en) * 1994-01-28 1998-04-28 Prolinx, Inc. Boronic compound complexing reagents and complexes
US5837878A (en) * 1994-01-28 1998-11-17 Prolinx, Inc. Boronic compound complexing reagents and highly stable complexes
US5777148A (en) * 1994-01-28 1998-07-07 Prolinx, Inc. Boronic compound complexing reagents and highly stable complexes
US5831046A (en) * 1996-08-05 1998-11-03 Prolinx, Incorporated Boronic acid-contaning nucleic acid monomers
US6630577B2 (en) * 1996-08-05 2003-10-07 Prolinx, Inc. 1,2-Phenylenediboronic acid reagents and complexes
US6075126A (en) * 1996-08-05 2000-06-13 Prolinx, Inc. Phenyldiboronic acid reagents and complexes
US6031117A (en) * 1999-03-19 2000-02-29 Prolinx Incorporated Boronic acid containing phosphoramidite reagents
US6013783A (en) * 1999-03-19 2000-01-11 Prolinx Incorporated Boronic acid containing oligonucleotides and polynucleotides
GB0005469D0 (en) * 2000-03-08 2000-04-26 Univ Cranfield A novel building block approach for designing affinity ligands for glycosylated haemoglobin HbA1c
WO2005119255A2 (en) * 2004-05-12 2005-12-15 Applera Corporation Constrained cis-diol-borate bioconjugation system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0295073A2 (en) * 1987-06-08 1988-12-14 Chromatochem, Inc. Chromatographic material
WO2000012540A1 (en) * 1998-08-28 2000-03-09 Eli Lilly And Company Reversible boronate complexes of 1,2-cis-diol cyclic-peptides
US20030073243A1 (en) * 2001-08-31 2003-04-17 Law Wai Tak Method for quantitative determination of glycated hemoglobin
WO2003102217A2 (en) * 2002-06-03 2003-12-11 Dow Corning Corporation Synthesis of cis-diols from aryl silanes
WO2005016859A2 (en) * 2003-08-14 2005-02-24 Cephalon, Inc. Proteasome inhibitors and methods of using the same

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GAMOH K. ET AL: "Stability and reversed-phase liquid chromatographic studies of cyclic boronates", ANALYTICAL SCIENCES, vol. 9, August 1993 (1993-08-01), pages 549 - 552, XP008065466 *
ZANETTE D. ET AL: "Evaluation of phenylboronate agarose for industrial-scale purification of erythropoietin from mammalian cell cultures", JOURNAL OF BIOTECHNOLOGY, vol. 101, 2003, pages 275 - 287, XP008065442 *

Also Published As

Publication number Publication date
WO2005119255A2 (en) 2005-12-15
US20070287825A1 (en) 2007-12-13
US20050277143A1 (en) 2005-12-15
US7399645B2 (en) 2008-07-15

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