WO2005124362A3 - Method and test kit for diagnosing ischaemic heart damage, in particular the latent, chronic types, by the serological detection of myosin light chain 1 - Google Patents

Method and test kit for diagnosing ischaemic heart damage, in particular the latent, chronic types, by the serological detection of myosin light chain 1 Download PDF

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Publication number
WO2005124362A3
WO2005124362A3 PCT/IB2005/002385 IB2005002385W WO2005124362A3 WO 2005124362 A3 WO2005124362 A3 WO 2005124362A3 IB 2005002385 W IB2005002385 W IB 2005002385W WO 2005124362 A3 WO2005124362 A3 WO 2005124362A3
Authority
WO
WIPO (PCT)
Prior art keywords
diagnosing
latent
light chain
myosin light
test kit
Prior art date
Application number
PCT/IB2005/002385
Other languages
German (de)
French (fr)
Other versions
WO2005124362B1 (en
WO2005124362A2 (en
Inventor
Viktor Ruzicka
Original Assignee
Biovendor Lab Medicine Inc
Viktor Ruzicka
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biovendor Lab Medicine Inc, Viktor Ruzicka filed Critical Biovendor Lab Medicine Inc
Publication of WO2005124362A2 publication Critical patent/WO2005124362A2/en
Publication of WO2005124362A3 publication Critical patent/WO2005124362A3/en
Publication of WO2005124362B1 publication Critical patent/WO2005124362B1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/325—Heart failure or cardiac arrest, e.g. cardiomyopathy, congestive heart failure

Abstract

The invention relates to a method for diagnosing ischaemic heart damage, in particular the latent and chronic types, by the serological detection of the myosin light chain 1, MLC 1, as a diagnostic marker in the blood of the patients concerned. The invention also relates to an enzyme immunoassay for detecting MLC 1. The invention can be used in the medical field and in particular the medical diagnostics field.
PCT/IB2005/002385 2004-06-17 2005-06-17 Method and test kit for diagnosing ischaemic heart damage, in particular the latent, chronic types, by the serological detection of myosin light chain 1 WO2005124362A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004029116 2004-06-17
DE102004029116.0 2004-06-17

Publications (3)

Publication Number Publication Date
WO2005124362A2 WO2005124362A2 (en) 2005-12-29
WO2005124362A3 true WO2005124362A3 (en) 2006-05-18
WO2005124362B1 WO2005124362B1 (en) 2006-08-03

Family

ID=35414977

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/002385 WO2005124362A2 (en) 2004-06-17 2005-06-17 Method and test kit for diagnosing ischaemic heart damage, in particular the latent, chronic types, by the serological detection of myosin light chain 1

Country Status (1)

Country Link
WO (1) WO2005124362A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5702905A (en) * 1994-09-28 1997-12-30 Spectral Diagnostics Monoclonal antibody to human ventricular myosin light chains
US5747274A (en) * 1990-10-12 1998-05-05 Spectral Diagnostics Inc. Method and device for diagnosing and distinguishing chest pain in early onset thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747274A (en) * 1990-10-12 1998-05-05 Spectral Diagnostics Inc. Method and device for diagnosing and distinguishing chest pain in early onset thereof
US5747274B1 (en) * 1990-10-12 1999-08-24 Spectral Diagnostics Inc Method and device for diagnosing and distinguishing chest pain in early onset thereof
US5702905A (en) * 1994-09-28 1997-12-30 Spectral Diagnostics Monoclonal antibody to human ventricular myosin light chains

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HANSEN MARK S ET AL: "Relation of circulating cardiac myosin light chain 1 isoform in stable severe congestive heart failure to survival and treatment with flosequinan.", AMERICAN JOURNAL OF CARDIOLOGY, vol. 90, no. 9, 1 November 2002 (2002-11-01), pages 969 - 973, XP002357172, ISSN: 0002-9149 *

Also Published As

Publication number Publication date
WO2005124362B1 (en) 2006-08-03
WO2005124362A2 (en) 2005-12-29

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