WO2006023700A3 - Magnetic resonance imaging interference immune device - Google Patents

Magnetic resonance imaging interference immune device Download PDF

Info

Publication number
WO2006023700A3
WO2006023700A3 PCT/US2005/029500 US2005029500W WO2006023700A3 WO 2006023700 A3 WO2006023700 A3 WO 2006023700A3 US 2005029500 W US2005029500 W US 2005029500W WO 2006023700 A3 WO2006023700 A3 WO 2006023700A3
Authority
WO
WIPO (PCT)
Prior art keywords
resonance imaging
magnetic resonance
interference immune
imaging interference
immune device
Prior art date
Application number
PCT/US2005/029500
Other languages
French (fr)
Other versions
WO2006023700A2 (en
Inventor
Robert W Gray
Original Assignee
Biophan Technologies Inc
Robert W Gray
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biophan Technologies Inc, Robert W Gray filed Critical Biophan Technologies Inc
Publication of WO2006023700A2 publication Critical patent/WO2006023700A2/en
Publication of WO2006023700A3 publication Critical patent/WO2006023700A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01BCABLES; CONDUCTORS; INSULATORS; SELECTION OF MATERIALS FOR THEIR CONDUCTIVE, INSULATING OR DIELECTRIC PROPERTIES
    • H01B7/00Insulated conductors or cables characterised by their form
    • H01B7/04Flexible cables, conductors, or cords, e.g. trailing cables
    • H01B7/048Flexible cables, conductors, or cords, e.g. trailing cables for implantation into a human or animal body, e.g. pacemaker leads
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01BCABLES; CONDUCTORS; INSULATORS; SELECTION OF MATERIALS FOR THEIR CONDUCTIVE, INSULATING OR DIELECTRIC PROPERTIES
    • H01B7/00Insulated conductors or cables characterised by their form
    • H01B7/06Extensible conductors or cables, e.g. self-coiling cords
    • H01B7/065Extensible conductors or cables, e.g. self-coiling cords having the shape of an helix

Abstract

A wire form includes a conductor having a distal end and a proximal end. The conductor is coiled and has a predetermined spacing between adjacent coils. The predetermined spacing provides a parasitic capacitance and an inductance. The parasitic capacitance and inductance have a resonance frequency tuned to about an excitation signal's frequency of a magnetic-resonance imaging scanner.
PCT/US2005/029500 2004-08-20 2005-08-19 Magnetic resonance imaging interference immune device WO2006023700A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US60347604P 2004-08-20 2004-08-20
US60/603,476 2004-08-20
US11/208,065 US8041433B2 (en) 2004-08-20 2005-08-19 Magnetic resonance imaging interference immune device
US11/208,065 2005-08-19

Publications (2)

Publication Number Publication Date
WO2006023700A2 WO2006023700A2 (en) 2006-03-02
WO2006023700A3 true WO2006023700A3 (en) 2007-04-19

Family

ID=35910621

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/029500 WO2006023700A2 (en) 2004-08-20 2005-08-19 Magnetic resonance imaging interference immune device

Country Status (2)

Country Link
US (1) US8041433B2 (en)
WO (1) WO2006023700A2 (en)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8244370B2 (en) * 2001-04-13 2012-08-14 Greatbatch Ltd. Band stop filter employing a capacitor and an inductor tank circuit to enhance MRI compatibility of active medical devices
US9295828B2 (en) 2001-04-13 2016-03-29 Greatbatch Ltd. Self-resonant inductor wound portion of an implantable lead for enhanced MRI compatibility of active implantable medical devices
CA2482202C (en) 2001-04-13 2012-07-03 Surgi-Vision, Inc. Systems and methods for magnetic-resonance-guided interventional procedures
US8014867B2 (en) * 2004-12-17 2011-09-06 Cardiac Pacemakers, Inc. MRI operation modes for implantable medical devices
US7917213B2 (en) 2005-11-04 2011-03-29 Kenergy, Inc. MRI compatible implanted electronic medical lead
US9901731B2 (en) * 2006-01-31 2018-02-27 Medtronic, Inc. Medical electrical lead having improved inductance
US20070179582A1 (en) * 2006-01-31 2007-08-02 Marshall Mark T Polymer reinforced coil conductor for torque transmission
US20070299490A1 (en) * 2006-06-23 2007-12-27 Zhongping Yang Radiofrequency (rf)-shunted sleeve head and use in electrical stimulation leads
US9020610B2 (en) * 2006-06-23 2015-04-28 Medtronic, Inc. Electrode system with shunt electrode
US9827415B2 (en) 2006-11-09 2017-11-28 Greatbatch Ltd. Implantable lead having multi-planar spiral inductor filter
US9468750B2 (en) 2006-11-09 2016-10-18 Greatbatch Ltd. Multilayer planar spiral inductor filter for medical therapeutic or diagnostic applications
US8239041B2 (en) 2010-08-02 2012-08-07 Greatbatch Ltd. Multilayer helical wave filter for medical therapeutic or diagnostic applications
US7610101B2 (en) 2006-11-30 2009-10-27 Cardiac Pacemakers, Inc. RF rejecting lead
WO2008117383A1 (en) * 2007-03-23 2008-10-02 Fujitsu Limited Electronic device, electronic apparatus mounting electronic device, article mounting electronic device, and method for manufacturing electronic device
US8086321B2 (en) 2007-12-06 2011-12-27 Cardiac Pacemakers, Inc. Selectively connecting the tip electrode during therapy for MRI shielding
US8275464B2 (en) 2007-12-06 2012-09-25 Cardiac Pacemakers, Inc. Leads with high surface resistance
AU2008335462B2 (en) * 2007-12-06 2014-02-20 Cardiac Pacemakers, Inc. Implantable lead having a variable coil conductor pitch
EP2224995B1 (en) * 2007-12-06 2015-11-25 Cardiac Pacemakers, Inc. Implantable lead with shielding
US8032228B2 (en) * 2007-12-06 2011-10-04 Cardiac Pacemakers, Inc. Method and apparatus for disconnecting the tip electrode during MRI
WO2009100003A1 (en) 2008-02-06 2009-08-13 Cardiac Pacemakers, Inc. Lead with mri compatible design features
US8311637B2 (en) * 2008-02-11 2012-11-13 Cardiac Pacemakers, Inc. Magnetic core flux canceling of ferrites in MRI
US8255055B2 (en) * 2008-02-11 2012-08-28 Cardiac Pacemakers, Inc. MRI shielding in electrodes using AC pacing
US8160717B2 (en) 2008-02-19 2012-04-17 Cardiac Pacemakers, Inc. Model reference identification and cancellation of magnetically-induced voltages in a gradient magnetic field
US10080889B2 (en) 2009-03-19 2018-09-25 Greatbatch Ltd. Low inductance and low resistance hermetically sealed filtered feedthrough for an AIMD
US9108066B2 (en) 2008-03-20 2015-08-18 Greatbatch Ltd. Low impedance oxide resistant grounded capacitor for an AIMD
US8103360B2 (en) 2008-05-09 2012-01-24 Foster Arthur J Medical lead coil conductor with spacer element
US8571661B2 (en) * 2008-10-02 2013-10-29 Cardiac Pacemakers, Inc. Implantable medical device responsive to MRI induced capture threshold changes
US20100106215A1 (en) * 2008-10-23 2010-04-29 Stubbs Scott R Systems and methods to detect implantable medical device configuaration changes affecting mri conditional safety
JP2012508640A (en) 2008-11-13 2012-04-12 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ Spiral wire in probe of deep brain stimulator
WO2010078552A1 (en) 2009-01-05 2010-07-08 Kenergy, Inc. Mri compatible electrical lead for an implantable electronic medical device
JP5389947B2 (en) 2009-02-19 2014-01-15 カーディアック ペースメイカーズ, インコーポレイテッド System for providing arrhythmia therapy in an MRI environment
US9084883B2 (en) * 2009-03-12 2015-07-21 Cardiac Pacemakers, Inc. Thin profile conductor assembly for medical device leads
DE112010001330T5 (en) 2009-03-26 2012-02-16 Kenergy Inc. MRI-compatible implantable connection electrode interface
US8478423B2 (en) * 2009-04-07 2013-07-02 Boston Scientific Neuromodulation Corporation Insulator layers for leads of implantable electric stimulation systems and methods of making and using
JP5542926B2 (en) * 2009-06-26 2014-07-09 カーディアック ペースメイカーズ, インコーポレイテッド Medical instrument lead comprising a conductor assembly consisting of a single wire coil with improved torque transfer performance and reduced heating by MRI
US8335572B2 (en) 2009-10-08 2012-12-18 Cardiac Pacemakers, Inc. Medical device lead including a flared conductive coil
WO2011043898A2 (en) * 2009-10-09 2011-04-14 Cardiac Pacemakers, Inc. Mri compatible medical device lead including transmission line notch filters
WO2011049684A1 (en) 2009-10-19 2011-04-28 Cardiac Pacemakers, Inc. Mri compatible tachycardia lead
US8554338B2 (en) * 2009-11-05 2013-10-08 Pacesetter, Inc. MRI-compatible implantable lead having a heat spreader and method of using same
WO2011071597A1 (en) 2009-12-08 2011-06-16 Cardiac Pacemakers, Inc. Implantable medical device with automatic tachycardia detection and control in mri environments
US20110144722A1 (en) * 2009-12-10 2011-06-16 Pacesetter, Inc. Mri-compatible implantable lead with improved lc resonant component
US20110152990A1 (en) * 2009-12-22 2011-06-23 Pacesetter, Inc. Mri compatible lead employing multiple miniature inductors
WO2011081697A1 (en) * 2009-12-30 2011-07-07 Cardiac Pacemakers, Inc. Apparatus to selectively increase medical device lead inner conductor inductance
AU2010337309B2 (en) 2009-12-30 2014-01-23 Cardiac Pacemakers, Inc. MRI-conditionally safe medical device lead
US8406895B2 (en) * 2009-12-30 2013-03-26 Cardiac Pacemakers, Inc. Implantable electrical lead including a cooling assembly to dissipate MRI induced electrode heat
US8391994B2 (en) 2009-12-31 2013-03-05 Cardiac Pacemakers, Inc. MRI conditionally safe lead with low-profile multi-layer conductor for longitudinal expansion
JP5542217B2 (en) 2009-12-31 2014-07-09 カーディアック ペースメイカーズ, インコーポレイテッド MRI conditional and safe lead with multilayer conductor
US8834657B2 (en) 2010-08-20 2014-09-16 Kenergy, Inc. Method of manufacturing an mri compatible conductive lead body
US8825181B2 (en) 2010-08-30 2014-09-02 Cardiac Pacemakers, Inc. Lead conductor with pitch and torque control for MRI conditionally safe use
WO2012067713A1 (en) 2010-11-18 2012-05-24 Cardiac Pacemakers, Inc. Insulative structure for mri compatible leads
US11198014B2 (en) 2011-03-01 2021-12-14 Greatbatch Ltd. Hermetically sealed filtered feedthrough assembly having a capacitor with an oxide resistant electrical connection to an active implantable medical device housing
US10596369B2 (en) 2011-03-01 2020-03-24 Greatbatch Ltd. Low equivalent series resistance RF filter for an active implantable medical device
US10350421B2 (en) 2013-06-30 2019-07-16 Greatbatch Ltd. Metallurgically bonded gold pocket pad for grounding an EMI filter to a hermetic terminal for an active implantable medical device
US9427596B2 (en) 2013-01-16 2016-08-30 Greatbatch Ltd. Low impedance oxide resistant grounded capacitor for an AIMD
US9931514B2 (en) 2013-06-30 2018-04-03 Greatbatch Ltd. Low impedance oxide resistant grounded capacitor for an AIMD
US10272252B2 (en) 2016-11-08 2019-04-30 Greatbatch Ltd. Hermetic terminal for an AIMD having a composite brazed conductive lead
WO2013066505A1 (en) 2011-11-04 2013-05-10 Cardiac Pacemakers, Inc. Implantable medical device lead including inner coil reverse-wound relative to shocking coil
AU2013249088B2 (en) 2012-04-20 2015-12-03 Cardiac Pacemakers, Inc. Implantable medical device lead including a unifilar coiled cable
US8954168B2 (en) 2012-06-01 2015-02-10 Cardiac Pacemakers, Inc. Implantable device lead including a distal electrode assembly with a coiled component
JP6069499B2 (en) 2012-08-31 2017-02-01 カーディアック ペースメイカーズ, インコーポレイテッド Lead wire with low peak MRI heating
WO2014062966A1 (en) 2012-10-18 2014-04-24 Cardiac Pacemakers, Inc. Inductive element for providing mri compatibility in an implantable medical device lead
USRE46699E1 (en) 2013-01-16 2018-02-06 Greatbatch Ltd. Low impedance oxide resistant grounded capacitor for an AIMD
EP2835148A1 (en) 2013-08-04 2015-02-11 Greatbatch Ltd. Multilayer planar spiral inductor filter for medical, therapeutic or diagnostic applications
EP3104933A1 (en) 2014-02-11 2016-12-21 Cardiac Pacemakers, Inc. Rf shield for an implantable lead
EP3110499B1 (en) 2014-02-26 2018-01-24 Cardiac Pacemakers, Inc. Construction of an mri-safe tachycardia lead
US10249415B2 (en) 2017-01-06 2019-04-02 Greatbatch Ltd. Process for manufacturing a leadless feedthrough for an active implantable medical device
US10905888B2 (en) 2018-03-22 2021-02-02 Greatbatch Ltd. Electrical connection for an AIMD EMI filter utilizing an anisotropic conductive layer
US10912945B2 (en) 2018-03-22 2021-02-09 Greatbatch Ltd. Hermetic terminal for an active implantable medical device having a feedthrough capacitor partially overhanging a ferrule for high effective capacitance area
KR102533089B1 (en) * 2018-12-20 2023-05-17 에이에스엠엘 네델란즈 비.브이. stage device

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5964705A (en) * 1997-08-22 1999-10-12 Image-Guided Drug Delivery System, Inc. MR-compatible medical devices
US7013180B2 (en) * 2002-01-29 2006-03-14 Medtronic, Inc. Conditioning of coupled electromagnetic signals on a lead

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH653559A5 (en) 1980-11-15 1986-01-15 Osypka Peter Pacemaker electrode
US5217010A (en) 1991-05-28 1993-06-08 The Johns Hopkins University Ecg amplifier and cardiac pacemaker for use during magnetic resonance imaging
US5727552A (en) 1996-01-11 1998-03-17 Medtronic, Inc. Catheter and electrical lead location system
DE19746735C2 (en) 1997-10-13 2003-11-06 Simag Gmbh Systeme Und Instr F NMR imaging method for the display, position determination or functional control of a device inserted into an examination object and device for use in such a method
US6032063A (en) 1997-12-09 2000-02-29 Vital Connections, Inc. Distributed resistance leadwire harness assembly for physiological monitoring during magnetic resonance imaging
US8244370B2 (en) 2001-04-13 2012-08-14 Greatbatch Ltd. Band stop filter employing a capacitor and an inductor tank circuit to enhance MRI compatibility of active medical devices
US7844319B2 (en) 1998-11-04 2010-11-30 Susil Robert C Systems and methods for magnetic-resonance-guided interventional procedures
US6701176B1 (en) 1998-11-04 2004-03-02 Johns Hopkins University School Of Medicine Magnetic-resonance-guided imaging, electrophysiology, and ablation
US6393314B1 (en) 1999-05-06 2002-05-21 General Electric Company RF driven resistive ablation system for use in MRI guided therapy
JP2003502085A (en) 1999-06-14 2003-01-21 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ MRI apparatus having anti-jamming supply leads for electrically connected equipment
US8002700B2 (en) 1999-12-30 2011-08-23 Medtronic, Inc. Communications system for an implantable medical device and a delivery device
US6501978B2 (en) 1999-12-30 2002-12-31 Transurgical, Inc. Interleaved operation of MRI and electronic equipment
US6471645B1 (en) 1999-12-30 2002-10-29 Medtronic, Inc. Communications system for an implantable device and a drug dispenser
US6925328B2 (en) 2000-04-20 2005-08-02 Biophan Technologies, Inc. MRI-compatible implantable device
US8527046B2 (en) 2000-04-20 2013-09-03 Medtronic, Inc. MRI-compatible implantable device
DE10030620A1 (en) 2000-06-28 2002-01-17 Karlsruhe Forschzent Device for injecting medical preparations under CT / MRI control
US6949929B2 (en) 2003-06-24 2005-09-27 Biophan Technologies, Inc. Magnetic resonance imaging interference immune device
US6564084B2 (en) 2001-03-02 2003-05-13 Draeger Medical, Inc. Magnetic field shielding and detecting device and method thereof
US6503272B2 (en) 2001-03-21 2003-01-07 Cordis Corporation Stent-based venous valves
US6675049B2 (en) 2001-07-17 2004-01-06 Medtronic, Inc. Method and apparatus for automatic implantable medical lead recognition and configuration
DE10293622D2 (en) 2001-08-08 2004-08-12 Buecker Arno Magnetic resonance compatible metallic endoprosthesis
US6944489B2 (en) 2001-10-31 2005-09-13 Medtronic, Inc. Method and apparatus for shunting induced currents in an electrical lead
US6871091B2 (en) 2001-10-31 2005-03-22 Medtronic, Inc. Apparatus and method for shunting induced currents in an electrical lead
US6700472B2 (en) 2001-12-11 2004-03-02 Intersil Americas Inc. Magnetic thin film inductors
US6799067B2 (en) 2001-12-26 2004-09-28 Advanced Cardiovascular Systems, Inc. MRI compatible guide wire
US6506972B1 (en) 2002-01-22 2003-01-14 Nanoset, Llc Magnetically shielded conductor
US6906256B1 (en) 2002-01-22 2005-06-14 Nanoset, Llc Nanomagnetic shielding assembly
US6844492B1 (en) 2002-01-22 2005-01-18 Nanoset, Llc Magnetically shielded conductor
US7162302B2 (en) 2002-03-04 2007-01-09 Nanoset Llc Magnetically shielded assembly
US6846985B2 (en) 2002-01-22 2005-01-25 Nanoset, Llc Magnetically shielded assembly
US20040210289A1 (en) 2002-03-04 2004-10-21 Xingwu Wang Novel nanomagnetic particles
WO2003061755A2 (en) 2002-01-22 2003-07-31 Nanoset, Llc Nanomagnetically shielded substrate
US6864418B2 (en) 2002-12-18 2005-03-08 Nanoset, Llc Nanomagnetically shielded substrate
US20050155779A1 (en) 2003-04-08 2005-07-21 Xingwu Wang Coated substrate assembly
US7765005B2 (en) 2004-02-12 2010-07-27 Greatbatch Ltd. Apparatus and process for reducing the susceptability of active implantable medical devices to medical procedures such as magnetic resonance imaging
US9155877B2 (en) 2004-03-30 2015-10-13 Medtronic, Inc. Lead electrode for use in an MRI-safe implantable medical device
US8989840B2 (en) 2004-03-30 2015-03-24 Medtronic, Inc. Lead electrode for use in an MRI-safe implantable medical device
US7877150B2 (en) 2004-03-30 2011-01-25 Medtronic, Inc. Lead electrode for use in an MRI-safe implantable medical device
US7174219B2 (en) 2004-03-30 2007-02-06 Medtronic, Inc. Lead electrode for use in an MRI-safe implantable medical device
US7844344B2 (en) 2004-03-30 2010-11-30 Medtronic, Inc. MRI-safe implantable lead
US7844343B2 (en) 2004-03-30 2010-11-30 Medtronic, Inc. MRI-safe implantable medical device
US8825180B2 (en) 2005-03-31 2014-09-02 Medtronic, Inc. Medical electrical lead with co-radial multi-conductor coil
US8027736B2 (en) 2005-04-29 2011-09-27 Medtronic, Inc. Lead electrode for use in an MRI-safe implantable medical device
US7853332B2 (en) 2005-04-29 2010-12-14 Medtronic, Inc. Lead electrode for use in an MRI-safe implantable medical device

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5964705A (en) * 1997-08-22 1999-10-12 Image-Guided Drug Delivery System, Inc. MR-compatible medical devices
US7013180B2 (en) * 2002-01-29 2006-03-14 Medtronic, Inc. Conditioning of coupled electromagnetic signals on a lead

Also Published As

Publication number Publication date
WO2006023700A2 (en) 2006-03-02
US20060041294A1 (en) 2006-02-23
US8041433B2 (en) 2011-10-18

Similar Documents

Publication Publication Date Title
WO2006023700A3 (en) Magnetic resonance imaging interference immune device
US9332926B2 (en) MRI imaging probe
US7205768B2 (en) Connection lead for an electrical accessory device of an MRI system
WO2011043898A3 (en) Mri compatible medical device lead including transmission line notch filters
EP1912329A3 (en) Inductance device and noise filter comprising the same
JP5226318B2 (en) Transmission path used in RF field
KR20210013567A (en) Radio frequency coil signal chain for low-field MRI system
JP2008529588A5 (en)
EP1130412A3 (en) Interface system for magnetic resonance imaging coils
WO2000064003A8 (en) Magnetic resonance imaging guidewire probe
WO2006078409A3 (en) Nmr rf coils with split movable capacitance bands
US7725160B2 (en) Tunable MRI enhancing device
WO1999010035A3 (en) Invasive medical device including an opposed solenoid rf coil for mri
WO2007138547A3 (en) Detuning a radio-frequency coil
DE60045731D1 (en) Head coil for imaging magnetic resonance
RU2524447C2 (en) Devices and cable connection to be used in multiresonant system of magnetic resonance
EP1113286A3 (en) Quadrature RF coil for MRI systems
EP0850595A1 (en) Nuclear magnetic resonance imaging apparatus
US8841909B2 (en) Balanced-to-unbalanced transformer for converting a symmetrical high-frequency signal into an asymmetrical high-frequency signal
WO2009134920A3 (en) Method and apparatus for magnetic resonance imaging and spectroscopy using multiple-mode coils
NL1020979A1 (en) High frequency coil for magnetic resonance imaging.
DE69317327D1 (en) Asymmetric high-frequency coil arrangement for magnetic resonance imaging
NL1011364C2 (en) Catheter with circuit for positioning and imaging.
EP1283529A3 (en) Mn-Zn ferrite and coil component using the same
DE60207099D1 (en) UNIVERSAL CONNECTING AND RECEIVING DEVICE FOR A DEVICE FOR IMAGING BY MEANS OF MAGNETIC RESONANCE

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NG NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU LV MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase