WO2007001342A3 - Exhaled breath condensate collection and assay system and method - Google Patents

Exhaled breath condensate collection and assay system and method Download PDF

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Publication number
WO2007001342A3
WO2007001342A3 PCT/US2005/029604 US2005029604W WO2007001342A3 WO 2007001342 A3 WO2007001342 A3 WO 2007001342A3 US 2005029604 W US2005029604 W US 2005029604W WO 2007001342 A3 WO2007001342 A3 WO 2007001342A3
Authority
WO
WIPO (PCT)
Prior art keywords
assay system
exhaled breath
condensate collection
breath condensate
determining
Prior art date
Application number
PCT/US2005/029604
Other languages
French (fr)
Other versions
WO2007001342A2 (en
WO2007001342A9 (en
Inventor
John F Hunt
Brian Walsh
Alfred R Baddour
Dan Mackey
Original Assignee
Univ Virginia
Respiratory Res Inc
John F Hunt
Brian Walsh
Alfred R Baddour
Dan Mackey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Virginia, Respiratory Res Inc, John F Hunt, Brian Walsh, Alfred R Baddour, Dan Mackey filed Critical Univ Virginia
Priority to CA002578615A priority Critical patent/CA2578615A1/en
Priority to US11/660,653 priority patent/US20080214947A1/en
Publication of WO2007001342A2 publication Critical patent/WO2007001342A2/en
Publication of WO2007001342A3 publication Critical patent/WO2007001342A3/en
Publication of WO2007001342A9 publication Critical patent/WO2007001342A9/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14539Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring pH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/083Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/097Devices for facilitating collection of breath or for directing breath into or through measuring devices

Abstract

A method and system that provides for minute-to-minute EBC pH monitoring (or for other EBC characteristic monitoring) of a subject that greatly assists in determining the time-course of airway pH changes (or other characteristic changes) in evolving disease processes, and may assist in determining the predictive ability of these tests, as well as determining response to therapy.
PCT/US2005/029604 2004-08-20 2005-08-19 Exhaled breath condensate collection and assay system and method WO2007001342A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002578615A CA2578615A1 (en) 2004-08-20 2005-08-19 Exhaled breath condensate collection and assay system and related method thereof
US11/660,653 US20080214947A1 (en) 2004-08-20 2005-08-19 Exhaled Breath Condensate Collection and Assay System and Method

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US60316904P 2004-08-20 2004-08-20
US60/603,169 2004-08-20
US69688605P 2005-07-06 2005-07-06
US60/696,886 2005-07-06

Publications (3)

Publication Number Publication Date
WO2007001342A2 WO2007001342A2 (en) 2007-01-04
WO2007001342A3 true WO2007001342A3 (en) 2007-03-22
WO2007001342A9 WO2007001342A9 (en) 2007-04-26

Family

ID=37595561

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/029604 WO2007001342A2 (en) 2004-08-20 2005-08-19 Exhaled breath condensate collection and assay system and method

Country Status (3)

Country Link
US (1) US20080214947A1 (en)
CA (1) CA2578615A1 (en)
WO (1) WO2007001342A2 (en)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6024089A (en) 1997-03-14 2000-02-15 Nelcor Puritan Bennett Incorporated System and method for setting and displaying ventilator alarms
FR2858236B1 (en) 2003-07-29 2006-04-28 Airox DEVICE AND METHOD FOR SUPPLYING RESPIRATORY GAS IN PRESSURE OR VOLUME
US8021310B2 (en) 2006-04-21 2011-09-20 Nellcor Puritan Bennett Llc Work of breathing display for a ventilation system
US7784461B2 (en) 2006-09-26 2010-08-31 Nellcor Puritan Bennett Llc Three-dimensional waveform display for a breathing assistance system
GB2451249A (en) * 2007-07-24 2009-01-28 Equine Healthcare Ltd A breath condensate collector
US8457706B2 (en) 2008-05-16 2013-06-04 Covidien Lp Estimation of a physiological parameter using a neural network
WO2010036816A1 (en) 2008-09-25 2010-04-01 Nellcor Puritan Bennett Llc Inversion-based feed-forward compensation of inspiratory trigger dynamics in medical ventilators
US8302602B2 (en) 2008-09-30 2012-11-06 Nellcor Puritan Bennett Llc Breathing assistance system with multiple pressure sensors
US8434479B2 (en) 2009-02-27 2013-05-07 Covidien Lp Flow rate compensation for transient thermal response of hot-wire anemometers
US8394030B2 (en) * 2009-03-18 2013-03-12 Carefusion 207, Inc. Exhaled breath condensate biometric marker measurement apparatus and method
US8439036B2 (en) 2009-12-01 2013-05-14 Covidien Lp Exhalation valve assembly with integral flow sensor
US8469031B2 (en) 2009-12-01 2013-06-25 Covidien Lp Exhalation valve assembly with integrated filter
US8469030B2 (en) 2009-12-01 2013-06-25 Covidien Lp Exhalation valve assembly with selectable contagious/non-contagious latch
US8439037B2 (en) 2009-12-01 2013-05-14 Covidien Lp Exhalation valve assembly with integrated filter and flow sensor
US8335992B2 (en) 2009-12-04 2012-12-18 Nellcor Puritan Bennett Llc Visual indication of settings changes on a ventilator graphical user interface
USD638852S1 (en) 2009-12-04 2011-05-31 Nellcor Puritan Bennett Llc Ventilator display screen with an alarm icon
US8924878B2 (en) 2009-12-04 2014-12-30 Covidien Lp Display and access to settings on a ventilator graphical user interface
US9119925B2 (en) 2009-12-04 2015-09-01 Covidien Lp Quick initiation of respiratory support via a ventilator user interface
USD649157S1 (en) 2009-12-04 2011-11-22 Nellcor Puritan Bennett Llc Ventilator display screen with a user interface
US8499252B2 (en) 2009-12-18 2013-07-30 Covidien Lp Display of respiratory data graphs on a ventilator graphical user interface
US9262588B2 (en) 2009-12-18 2016-02-16 Covidien Lp Display of respiratory data graphs on a ventilator graphical user interface
USD655405S1 (en) 2010-04-27 2012-03-06 Nellcor Puritan Bennett Llc Filter and valve body for an exhalation module
USD653749S1 (en) 2010-04-27 2012-02-07 Nellcor Puritan Bennett Llc Exhalation module filter body
USD655809S1 (en) 2010-04-27 2012-03-13 Nellcor Puritan Bennett Llc Valve body with integral flow meter for an exhalation module
WO2012006250A1 (en) * 2010-07-06 2012-01-12 Deton Corp. System for airborne bacterial sample collection and analysis
US9629971B2 (en) 2011-04-29 2017-04-25 Covidien Lp Methods and systems for exhalation control and trajectory optimization
US9364624B2 (en) 2011-12-07 2016-06-14 Covidien Lp Methods and systems for adaptive base flow
US9498589B2 (en) 2011-12-31 2016-11-22 Covidien Lp Methods and systems for adaptive base flow and leak compensation
US9144658B2 (en) 2012-04-30 2015-09-29 Covidien Lp Minimizing imposed expiratory resistance of mechanical ventilator by optimizing exhalation valve control
US10362967B2 (en) 2012-07-09 2019-07-30 Covidien Lp Systems and methods for missed breath detection and indication
USD731049S1 (en) 2013-03-05 2015-06-02 Covidien Lp EVQ housing of an exhalation module
USD744095S1 (en) 2013-03-08 2015-11-24 Covidien Lp Exhalation module EVQ internal flow sensor
USD731065S1 (en) 2013-03-08 2015-06-02 Covidien Lp EVQ pressure sensor filter of an exhalation module
USD692556S1 (en) 2013-03-08 2013-10-29 Covidien Lp Expiratory filter body of an exhalation module
USD736905S1 (en) 2013-03-08 2015-08-18 Covidien Lp Exhalation module EVQ housing
USD731048S1 (en) 2013-03-08 2015-06-02 Covidien Lp EVQ diaphragm of an exhalation module
USD701601S1 (en) 2013-03-08 2014-03-25 Covidien Lp Condensate vial of an exhalation module
USD693001S1 (en) 2013-03-08 2013-11-05 Covidien Lp Neonate expiratory filter assembly of an exhalation module
EP2970858A4 (en) 2013-03-12 2016-11-16 Deton Corp System for breath sample collection and analysis
US9950135B2 (en) 2013-03-15 2018-04-24 Covidien Lp Maintaining an exhalation valve sensor assembly
GB201313817D0 (en) * 2013-08-01 2013-09-18 Maddison Product Design Ltd Exhaled breath condensate collector
EP3096824A1 (en) 2014-01-24 2016-11-30 Cole Research&Design, Inc. Oral suction device
US9950129B2 (en) 2014-10-27 2018-04-24 Covidien Lp Ventilation triggering using change-point detection
USD775345S1 (en) 2015-04-10 2016-12-27 Covidien Lp Ventilator console
CN108780081B (en) 2015-08-10 2021-04-09 Essenlix公司 Simplified-procedure, small-sample, rapid, easy-to-use bio/chemical analysis apparatus and method
MX2018003147A (en) * 2015-09-14 2018-09-06 Essenlix Corp Device and system for collecting and analyzing vapor condensate, particularly exhaled breath condensate, as well as method of using the same.
MX2018003148A (en) 2015-09-14 2019-02-20 Essenlix Corp Device and system for analyzing a sample, particularly blood, as well as methods of using the same.
US10502665B2 (en) 2016-04-18 2019-12-10 University Of Maryland, College Park Aerosol collection system and method
WO2018119318A1 (en) 2016-12-21 2018-06-28 Essenlix Corporation Devices and methods for authenticating a sample and use of the same
CN111246945A (en) 2017-02-07 2020-06-05 Essenlix公司 Compressed open flow assay and use
CA3053002A1 (en) 2017-02-08 2018-08-16 Essenlix Corp. Bio/chemical material extraction and assay
CA3053114A1 (en) 2017-02-09 2018-08-16 Essenlix Corporation Assay using different spacing heights
JP2020507770A (en) 2017-02-09 2020-03-12 エッセンリックス コーポレーション Colorimetric assay
CA3053132A1 (en) 2017-02-09 2018-08-16 Essenlix Corp. Assay with amplification
CA3053301A1 (en) 2017-02-16 2018-08-23 Essenlix Corporation Assay with textured surface
GB201704367D0 (en) 2017-03-20 2017-05-03 Exhalation Tech Ltd A breath condensate analyser
US11280706B2 (en) 2017-08-01 2022-03-22 Essenlix Corporation Dilution calibration
WO2019028133A1 (en) 2017-08-01 2019-02-07 Essenlix Corporation Devices and methods for examining drug effects on microorganisms
WO2019028123A1 (en) 2017-08-01 2019-02-07 Essenlix Corporation Sample collection, holding, and assaying
US11393561B2 (en) 2017-10-13 2022-07-19 Essenlix Corporation Devices and methods for authenticating a medical test and use of the same
US10807095B2 (en) 2017-10-26 2020-10-20 Essenlix Corporation Making and tracking assay card
US11237113B2 (en) 2017-10-26 2022-02-01 Essenlix Corporation Rapid pH measurement
US11609224B2 (en) 2017-10-26 2023-03-21 Essenlix Corporation Devices and methods for white blood cell analyses
US11648551B2 (en) 2017-12-12 2023-05-16 Essenlix Corporation Sample manipulation and assay with rapid temperature change
CN112534259A (en) 2017-12-14 2021-03-19 Essenlix公司 Device, system and method for monitoring hair
US11156606B2 (en) 2018-01-11 2021-10-26 Essenlix Corporation Homogeneous assay (II)
WO2019178175A1 (en) * 2018-03-13 2019-09-19 Gilmartin Charles Hcl sensor platform for respiratory assist device
US11885952B2 (en) 2018-07-30 2024-01-30 Essenlix Corporation Optics, device, and system for assaying and imaging
US11896767B2 (en) 2020-03-20 2024-02-13 Covidien Lp Model-driven system integration in medical ventilators
JP2023522357A (en) * 2020-04-19 2023-05-30 ジョン・ジェイ・ダニエルズ Mask-based diagnostic system using exhaled breath condensate
EP4146067A1 (en) * 2020-05-06 2023-03-15 Jerry Aguren A photonic method and apparatus for detecting compounds and pathogens in a respiratory sample
US11672934B2 (en) 2020-05-12 2023-06-13 Covidien Lp Remote ventilator adjustment
WO2023014887A1 (en) * 2021-08-04 2023-02-09 The Trustees Of Indiana University Methods of treating compromised lung function and assessing clinical improvement

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6033368A (en) * 1996-03-28 2000-03-07 Nitromed, Inc. Condensate colorimetric nitrogen oxide analyzer
US20040127808A1 (en) * 2001-04-17 2004-07-01 Vaughan John W. Device and method for assessing asthma and other diseases
US20040162500A1 (en) * 2003-02-14 2004-08-19 The Charlotte-Mecklenburg Hospital Authority Device and method for collection of exhaled alveolar breath condensate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1139870A4 (en) * 1998-12-18 2004-07-28 Univ Virginia Device and method for monitoring asthma
US7118537B2 (en) * 2001-04-30 2006-10-10 Respiratory Research, Inc. Method and device for collecting and analyzing exhaled breath
US7101341B2 (en) * 2003-04-15 2006-09-05 Ross Tsukashima Respiratory monitoring, diagnostic and therapeutic system

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6033368A (en) * 1996-03-28 2000-03-07 Nitromed, Inc. Condensate colorimetric nitrogen oxide analyzer
US20040127808A1 (en) * 2001-04-17 2004-07-01 Vaughan John W. Device and method for assessing asthma and other diseases
US20040162500A1 (en) * 2003-02-14 2004-08-19 The Charlotte-Mecklenburg Hospital Authority Device and method for collection of exhaled alveolar breath condensate

Also Published As

Publication number Publication date
CA2578615A1 (en) 2007-01-04
WO2007001342A2 (en) 2007-01-04
US20080214947A1 (en) 2008-09-04
WO2007001342A9 (en) 2007-04-26

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