WO2007046989A3 - Apparatus and methods for the selective removal of tissue using combinations of ultrasonic energy and cryogenic energy - Google Patents

Apparatus and methods for the selective removal of tissue using combinations of ultrasonic energy and cryogenic energy Download PDF

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Publication number
WO2007046989A3
WO2007046989A3 PCT/US2006/035864 US2006035864W WO2007046989A3 WO 2007046989 A3 WO2007046989 A3 WO 2007046989A3 US 2006035864 W US2006035864 W US 2006035864W WO 2007046989 A3 WO2007046989 A3 WO 2007046989A3
Authority
WO
WIPO (PCT)
Prior art keywords
tissue
energy
methods
cryogenic
ultrasonic
Prior art date
Application number
PCT/US2006/035864
Other languages
French (fr)
Other versions
WO2007046989A2 (en
Inventor
Eilaz P Babaev
Original Assignee
Eilaz P Babaev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eilaz P Babaev filed Critical Eilaz P Babaev
Priority to JP2008535538A priority Critical patent/JP2009511168A/en
Priority to EP06803615A priority patent/EP1933713A4/en
Publication of WO2007046989A2 publication Critical patent/WO2007046989A2/en
Publication of WO2007046989A3 publication Critical patent/WO2007046989A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B18/0206—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques ultrasonic, e.g. for destroying tissue or enhancing freezing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B18/0218—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques with open-end cryogenic probe, e.g. for spraying fluid directly on tissue or via a tissue-contacting porous tip
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
    • A61B2017/320069—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic for ablating tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
    • A61B2017/320089—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic node location
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0231—Characteristics of handpieces or probes
    • A61B2018/0262—Characteristics of handpieces or probes using a circulating cryogenic fluid

Abstract

Ultrasonic apparatus and method for selective and targeted removal of unwanted tissues are disclosed. The apparatus and methods may utilize combinations of ultrasonic and cryogenic energy for the selective removal of tissue. The apparatus generates and delivers to the tissue both cryogenic and ultrasonic energy either in combination or in sequence and provides resize ablation of unwanted tissue parts and may be used on other body tissues including internal organs.
PCT/US2006/035864 2005-10-13 2006-09-15 Apparatus and methods for the selective removal of tissue using combinations of ultrasonic energy and cryogenic energy WO2007046989A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2008535538A JP2009511168A (en) 2005-10-13 2006-09-15 Apparatus and method for selective removal of tissue using a combination of ultrasonic energy and cryogenic energy
EP06803615A EP1933713A4 (en) 2005-10-13 2006-09-15 Apparatus and methods for the selective removal of tissue using combinations of ultrasonic energy and cryogenic energy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/250,870 US7572268B2 (en) 2005-10-13 2005-10-13 Apparatus and methods for the selective removal of tissue using combinations of ultrasonic energy and cryogenic energy
US11/250,870 2005-10-13

Publications (2)

Publication Number Publication Date
WO2007046989A2 WO2007046989A2 (en) 2007-04-26
WO2007046989A3 true WO2007046989A3 (en) 2007-07-12

Family

ID=37949016

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/035864 WO2007046989A2 (en) 2005-10-13 2006-09-15 Apparatus and methods for the selective removal of tissue using combinations of ultrasonic energy and cryogenic energy

Country Status (6)

Country Link
US (1) US7572268B2 (en)
EP (1) EP1933713A4 (en)
JP (1) JP2009511168A (en)
KR (1) KR20080057338A (en)
CN (1) CN101287414A (en)
WO (1) WO2007046989A2 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7830070B2 (en) 2008-02-12 2010-11-09 Bacoustics, Llc Ultrasound atomization system
US7846341B2 (en) 2006-12-04 2010-12-07 Bacoustics, Llc Method of ultrasonically treating a continuous flow of fluid
US7943352B2 (en) 2006-03-29 2011-05-17 Bacoustics, Llc Apparatus and methods for vaccine development using ultrasound technology
US8016208B2 (en) 2008-02-08 2011-09-13 Bacoustics, Llc Echoing ultrasound atomization and mixing system

Families Citing this family (189)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8235919B2 (en) 2001-01-12 2012-08-07 Celleration, Inc. Ultrasonic method and device for wound treatment
US7179449B2 (en) * 2001-01-30 2007-02-20 Barnes-Jewish Hospital Enhanced ultrasound detection with temperature-dependent contrast agents
US11229472B2 (en) 2001-06-12 2022-01-25 Cilag Gmbh International Modular battery powered handheld surgical instrument with multiple magnetic position sensors
US8840608B2 (en) 2002-03-15 2014-09-23 The General Hospital Corporation Methods and devices for selective disruption of fatty tissue by controlled cooling
CN110522505B (en) * 2002-03-15 2023-04-25 总医院公司 System for selective destruction of adipose tissue by controlled cooling
US20040030254A1 (en) * 2002-08-07 2004-02-12 Eilaz Babaev Device and method for ultrasound wound debridement
US8182501B2 (en) 2004-02-27 2012-05-22 Ethicon Endo-Surgery, Inc. Ultrasonic surgical shears and method for sealing a blood vessel using same
JP5009159B2 (en) 2004-10-08 2012-08-22 エシコン・エンド−サージェリィ・インコーポレイテッド Ultrasonic surgical instrument
US7850683B2 (en) * 2005-05-20 2010-12-14 Myoscience, Inc. Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat)
US7713266B2 (en) * 2005-05-20 2010-05-11 Myoscience, Inc. Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat)
US20070031611A1 (en) * 2005-08-04 2007-02-08 Babaev Eilaz P Ultrasound medical stent coating method and device
US8277472B2 (en) * 2005-10-13 2012-10-02 Eilaz Babaev Deflector shield for use with multiple wound care devices
US7842032B2 (en) * 2005-10-13 2010-11-30 Bacoustics, Llc Apparatus and methods for the selective removal of tissue
US20070191713A1 (en) 2005-10-14 2007-08-16 Eichmann Stephen E Ultrasonic device for cutting and coagulating
US7621930B2 (en) 2006-01-20 2009-11-24 Ethicon Endo-Surgery, Inc. Ultrasound medical instrument having a medical ultrasonic blade
US20090221955A1 (en) * 2006-08-08 2009-09-03 Bacoustics, Llc Ablative ultrasonic-cryogenic methods
US20080039727A1 (en) * 2006-08-08 2008-02-14 Eilaz Babaev Ablative Cardiac Catheter System
US9132031B2 (en) 2006-09-26 2015-09-15 Zeltiq Aesthetics, Inc. Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile
US8192474B2 (en) 2006-09-26 2012-06-05 Zeltiq Aesthetics, Inc. Tissue treatment methods
US9254162B2 (en) 2006-12-21 2016-02-09 Myoscience, Inc. Dermal and transdermal cryogenic microprobe systems
US8491521B2 (en) 2007-01-04 2013-07-23 Celleration, Inc. Removable multi-channel applicator nozzle
US8409185B2 (en) * 2007-02-16 2013-04-02 Myoscience, Inc. Replaceable and/or easily removable needle systems for dermal and transdermal cryogenic remodeling
US8142461B2 (en) 2007-03-22 2012-03-27 Ethicon Endo-Surgery, Inc. Surgical instruments
US8911460B2 (en) 2007-03-22 2014-12-16 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instruments
US8057498B2 (en) 2007-11-30 2011-11-15 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instrument blades
US20080243047A1 (en) * 2007-03-27 2008-10-02 Babaev Eilaz P Ultrasound wound care device
US20080287839A1 (en) 2007-05-18 2008-11-20 Juniper Medical, Inc. Method of enhanced removal of heat from subcutaneous lipid-rich cells and treatment apparatus having an actuator
US8523927B2 (en) 2007-07-13 2013-09-03 Zeltiq Aesthetics, Inc. System for treating lipid-rich regions
US8523889B2 (en) 2007-07-27 2013-09-03 Ethicon Endo-Surgery, Inc. Ultrasonic end effectors with increased active length
US8882791B2 (en) * 2007-07-27 2014-11-11 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instruments
US8808319B2 (en) 2007-07-27 2014-08-19 Ethicon Endo-Surgery, Inc. Surgical instruments
US9044261B2 (en) 2007-07-31 2015-06-02 Ethicon Endo-Surgery, Inc. Temperature controlled ultrasonic surgical instruments
US8512365B2 (en) 2007-07-31 2013-08-20 Ethicon Endo-Surgery, Inc. Surgical instruments
US8430898B2 (en) 2007-07-31 2013-04-30 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instruments
EP3488833A1 (en) 2007-08-21 2019-05-29 Zeltiq Aesthetics, Inc. Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue
US8623027B2 (en) 2007-10-05 2014-01-07 Ethicon Endo-Surgery, Inc. Ergonomic surgical instruments
US8298216B2 (en) * 2007-11-14 2012-10-30 Myoscience, Inc. Pain management using cryogenic remodeling
US10010339B2 (en) 2007-11-30 2018-07-03 Ethicon Llc Ultrasonic surgical blades
US20090198157A1 (en) * 2008-02-01 2009-08-06 Eilaz Babaev Ultrasound moxibustion method and device
US7950594B2 (en) * 2008-02-11 2011-05-31 Bacoustics, Llc Mechanical and ultrasound atomization and mixing system
US20090228033A1 (en) * 2008-03-07 2009-09-10 Bacoustics, Llc Ultrasonic scalpel method
US20090228032A1 (en) * 2008-03-06 2009-09-10 Bacoustics, Llc Ultrasonic scalpel
US20090299235A1 (en) * 2008-06-03 2009-12-03 Eilaz Babaev Ultrasonic Endometrial Cryoablation Device
US9089360B2 (en) 2008-08-06 2015-07-28 Ethicon Endo-Surgery, Inc. Devices and techniques for cutting and coagulating tissue
US8323220B2 (en) * 2008-09-19 2012-12-04 Eilaz Babaev Spider vein treatment apparatus
US8376969B2 (en) * 2008-09-22 2013-02-19 Bacoustics, Llc Methods for treatment of spider veins
US8603073B2 (en) 2008-12-17 2013-12-10 Zeltiq Aesthetics, Inc. Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells
EP2373239B1 (en) 2008-12-22 2013-08-14 Myoscience, Inc. Integrated cryosurgical system with refrigerant and electrical power source
US7967814B2 (en) * 2009-02-05 2011-06-28 Icecure Medical Ltd. Cryoprobe with vibrating mechanism
US20100274236A1 (en) * 2009-04-23 2010-10-28 Krimsky William S Apparatuses and methods for applying a cryogenic effect to tissue and cutting tissue
WO2010127315A2 (en) 2009-04-30 2010-11-04 Zeltiq Aesthetics, Inc. Device, system and method of removing heat from subcutaneous lipid-rich cells
US9700339B2 (en) 2009-05-20 2017-07-11 Ethicon Endo-Surgery, Inc. Coupling arrangements and methods for attaching tools to ultrasonic surgical instruments
US8663220B2 (en) 2009-07-15 2014-03-04 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instruments
US8986302B2 (en) 2009-10-09 2015-03-24 Ethicon Endo-Surgery, Inc. Surgical generator for ultrasonic and electrosurgical devices
USRE47996E1 (en) 2009-10-09 2020-05-19 Ethicon Llc Surgical generator for ultrasonic and electrosurgical devices
US9168054B2 (en) 2009-10-09 2015-10-27 Ethicon Endo-Surgery, Inc. Surgical generator for ultrasonic and electrosurgical devices
US10441345B2 (en) 2009-10-09 2019-10-15 Ethicon Llc Surgical generator for ultrasonic and electrosurgical devices
US11090104B2 (en) 2009-10-09 2021-08-17 Cilag Gmbh International Surgical generator for ultrasonic and electrosurgical devices
CN102791227A (en) 2010-01-25 2012-11-21 斯尔替克美学股份有限公司 Home-use applicators for non-invasively removing heat from subcutaneous lipid-rich cells via phase change coolants, and associated devices, systems and methods
US8486096B2 (en) 2010-02-11 2013-07-16 Ethicon Endo-Surgery, Inc. Dual purpose surgical instrument for cutting and coagulating tissue
US8951272B2 (en) 2010-02-11 2015-02-10 Ethicon Endo-Surgery, Inc. Seal arrangements for ultrasonically powered surgical instruments
US8469981B2 (en) 2010-02-11 2013-06-25 Ethicon Endo-Surgery, Inc. Rotatable cutting implement arrangements for ultrasonic surgical instruments
US8579928B2 (en) 2010-02-11 2013-11-12 Ethicon Endo-Surgery, Inc. Outer sheath and blade arrangements for ultrasonic surgical instruments
US8961547B2 (en) 2010-02-11 2015-02-24 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instruments with moving cutting implement
US8676338B2 (en) 2010-07-20 2014-03-18 Zeltiq Aesthetics, Inc. Combined modality treatment systems, methods and apparatus for body contouring applications
US8795327B2 (en) 2010-07-22 2014-08-05 Ethicon Endo-Surgery, Inc. Electrosurgical instrument with separate closure and cutting members
US9192431B2 (en) 2010-07-23 2015-11-24 Ethicon Endo-Surgery, Inc. Electrosurgical cutting and sealing instrument
WO2012103242A1 (en) 2011-01-25 2012-08-02 Zeltiq Aesthetics, Inc. Devices, application systems and methods with localized heat flux zones for removing heat from subcutaneous lipid-rich cells
US9259265B2 (en) 2011-07-22 2016-02-16 Ethicon Endo-Surgery, Llc Surgical instruments for tensioning tissue
US9314290B2 (en) 2012-01-13 2016-04-19 Myoscience, Inc. Cryogenic needle with freeze zone regulation
US9241753B2 (en) 2012-01-13 2016-01-26 Myoscience, Inc. Skin protection for subdermal cryogenic remodeling for cosmetic and other treatments
EP2802278B1 (en) 2012-01-13 2016-12-07 Myoscience, Inc. Cryogenic probe filtration system
US9017318B2 (en) 2012-01-20 2015-04-28 Myoscience, Inc. Cryogenic probe system and method
EP2811932B1 (en) 2012-02-10 2019-06-26 Ethicon LLC Robotically controlled surgical instrument
US9439668B2 (en) 2012-04-09 2016-09-13 Ethicon Endo-Surgery, Llc Switch arrangements for ultrasonic surgical instruments
US9237921B2 (en) 2012-04-09 2016-01-19 Ethicon Endo-Surgery, Inc. Devices and techniques for cutting and coagulating tissue
US9724118B2 (en) 2012-04-09 2017-08-08 Ethicon Endo-Surgery, Llc Techniques for cutting and coagulating tissue for ultrasonic surgical instruments
US20140005705A1 (en) 2012-06-29 2014-01-02 Ethicon Endo-Surgery, Inc. Surgical instruments with articulating shafts
US9408622B2 (en) 2012-06-29 2016-08-09 Ethicon Endo-Surgery, Llc Surgical instruments with articulating shafts
US9326788B2 (en) 2012-06-29 2016-05-03 Ethicon Endo-Surgery, Llc Lockout mechanism for use with robotic electrosurgical device
US9393037B2 (en) 2012-06-29 2016-07-19 Ethicon Endo-Surgery, Llc Surgical instruments with articulating shafts
US9820768B2 (en) 2012-06-29 2017-11-21 Ethicon Llc Ultrasonic surgical instruments with control mechanisms
US20140005702A1 (en) 2012-06-29 2014-01-02 Ethicon Endo-Surgery, Inc. Ultrasonic surgical instruments with distally positioned transducers
US9198714B2 (en) 2012-06-29 2015-12-01 Ethicon Endo-Surgery, Inc. Haptic feedback devices for surgical robot
US9351754B2 (en) 2012-06-29 2016-05-31 Ethicon Endo-Surgery, Llc Ultrasonic surgical instruments with distally positioned jaw assemblies
US9226767B2 (en) 2012-06-29 2016-01-05 Ethicon Endo-Surgery, Inc. Closed feedback control for electrosurgical device
BR112015007010B1 (en) 2012-09-28 2022-05-31 Ethicon Endo-Surgery, Inc end actuator
US9095367B2 (en) 2012-10-22 2015-08-04 Ethicon Endo-Surgery, Inc. Flexible harmonic waveguides/blades for surgical instruments
AU2013342257B2 (en) 2012-11-08 2018-08-30 Smith & Nephew, Inc. Improved reattachment of detached cartilage to subchondral bone
AU2013342255B2 (en) 2012-11-08 2017-05-04 Smith & Nephew, Inc. Methods and compositions suitable for improved reattachment of detached cartilage to subchondral bone
US20140135804A1 (en) 2012-11-15 2014-05-15 Ethicon Endo-Surgery, Inc. Ultrasonic and electrosurgical devices
US10226273B2 (en) 2013-03-14 2019-03-12 Ethicon Llc Mechanical fasteners for use with surgical energy devices
US9545523B2 (en) 2013-03-14 2017-01-17 Zeltiq Aesthetics, Inc. Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue
US9844460B2 (en) 2013-03-14 2017-12-19 Zeltiq Aesthetics, Inc. Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same
US9295512B2 (en) 2013-03-15 2016-03-29 Myoscience, Inc. Methods and devices for pain management
CN105208954B (en) 2013-03-15 2019-06-04 肌肉科技股份有限公司 Low temperature Blunt dissection method and apparatus
US9610112B2 (en) 2013-03-15 2017-04-04 Myoscience, Inc. Cryogenic enhancement of joint function, alleviation of joint stiffness and/or alleviation of pain associated with osteoarthritis
US9241728B2 (en) 2013-03-15 2016-01-26 Ethicon Endo-Surgery, Inc. Surgical instrument with multiple clamping mechanisms
US10016229B2 (en) 2013-03-15 2018-07-10 Myoscience, Inc. Methods and systems for treatment of occipital neuralgia
US9622767B2 (en) 2013-09-11 2017-04-18 Covidien Lp Ultrasonic surgical instrument with cooling system
US9814514B2 (en) 2013-09-13 2017-11-14 Ethicon Llc Electrosurgical (RF) medical instruments for cutting and coagulating tissue
EP3065658B1 (en) 2013-11-05 2021-03-31 Pacira CryoTech, Inc. Secure cryosurgical treatment system
US9265926B2 (en) 2013-11-08 2016-02-23 Ethicon Endo-Surgery, Llc Electrosurgical devices
AU2014355072A1 (en) 2013-11-26 2016-06-02 Alliqua Biomedical, Inc. Systems and methods for producing and delivering ultrasonic therapies for wound treatment and healing
GB2521229A (en) 2013-12-16 2015-06-17 Ethicon Endo Surgery Inc Medical device
GB2521228A (en) 2013-12-16 2015-06-17 Ethicon Endo Surgery Inc Medical device
US9795436B2 (en) 2014-01-07 2017-10-24 Ethicon Llc Harvesting energy from a surgical generator
US9861421B2 (en) 2014-01-31 2018-01-09 Zeltiq Aesthetics, Inc. Compositions, treatment systems and methods for improved cooling of lipid-rich tissue
US9554854B2 (en) 2014-03-18 2017-01-31 Ethicon Endo-Surgery, Llc Detecting short circuits in electrosurgical medical devices
US10675176B1 (en) 2014-03-19 2020-06-09 Zeltiq Aesthetics, Inc. Treatment systems, devices, and methods for cooling targeted tissue
USD777338S1 (en) 2014-03-20 2017-01-24 Zeltiq Aesthetics, Inc. Cryotherapy applicator for cooling tissue
US10092310B2 (en) 2014-03-27 2018-10-09 Ethicon Llc Electrosurgical devices
US10463421B2 (en) 2014-03-27 2019-11-05 Ethicon Llc Two stage trigger, clamp and cut bipolar vessel sealer
US9737355B2 (en) 2014-03-31 2017-08-22 Ethicon Llc Controlling impedance rise in electrosurgical medical devices
US9913680B2 (en) 2014-04-15 2018-03-13 Ethicon Llc Software algorithms for electrosurgical instruments
US10952891B1 (en) 2014-05-13 2021-03-23 Zeltiq Aesthetics, Inc. Treatment systems with adjustable gap applicators and methods for cooling tissue
US10285724B2 (en) 2014-07-31 2019-05-14 Ethicon Llc Actuation mechanisms and load adjustment assemblies for surgical instruments
US10935174B2 (en) 2014-08-19 2021-03-02 Zeltiq Aesthetics, Inc. Stress relief couplings for cryotherapy apparatuses
US10568759B2 (en) 2014-08-19 2020-02-25 Zeltiq Aesthetics, Inc. Treatment systems, small volume applicators, and methods for treating submental tissue
US10639092B2 (en) 2014-12-08 2020-05-05 Ethicon Llc Electrode configurations for surgical instruments
US10245095B2 (en) 2015-02-06 2019-04-02 Ethicon Llc Electrosurgical instrument with rotation and articulation mechanisms
US10342602B2 (en) 2015-03-17 2019-07-09 Ethicon Llc Managing tissue treatment
US10321950B2 (en) 2015-03-17 2019-06-18 Ethicon Llc Managing tissue treatment
US10595929B2 (en) 2015-03-24 2020-03-24 Ethicon Llc Surgical instruments with firing system overload protection mechanisms
US10034684B2 (en) 2015-06-15 2018-07-31 Ethicon Llc Apparatus and method for dissecting and coagulating tissue
US11020140B2 (en) 2015-06-17 2021-06-01 Cilag Gmbh International Ultrasonic surgical blade for use with ultrasonic surgical instruments
US11141213B2 (en) 2015-06-30 2021-10-12 Cilag Gmbh International Surgical instrument with user adaptable techniques
US11051873B2 (en) 2015-06-30 2021-07-06 Cilag Gmbh International Surgical system with user adaptable techniques employing multiple energy modalities based on tissue parameters
US10898256B2 (en) 2015-06-30 2021-01-26 Ethicon Llc Surgical system with user adaptable techniques based on tissue impedance
US10034704B2 (en) 2015-06-30 2018-07-31 Ethicon Llc Surgical instrument with user adaptable algorithms
US11129669B2 (en) 2015-06-30 2021-09-28 Cilag Gmbh International Surgical system with user adaptable techniques based on tissue type
US10357303B2 (en) 2015-06-30 2019-07-23 Ethicon Llc Translatable outer tube for sealing using shielded lap chole dissector
US10154852B2 (en) 2015-07-01 2018-12-18 Ethicon Llc Ultrasonic surgical blade with improved cutting and coagulation features
US11033322B2 (en) 2015-09-30 2021-06-15 Ethicon Llc Circuit topologies for combined generator
US10595930B2 (en) 2015-10-16 2020-03-24 Ethicon Llc Electrode wiping surgical device
ES2892598T3 (en) 2015-10-19 2022-02-04 Zeltiq Aesthetics Inc Vascular treatment methods to cool vascular structures
US10179022B2 (en) 2015-12-30 2019-01-15 Ethicon Llc Jaw position impedance limiter for electrosurgical instrument
US10575892B2 (en) 2015-12-31 2020-03-03 Ethicon Llc Adapter for electrical surgical instruments
JP6833869B2 (en) 2016-01-07 2021-02-24 ゼルティック エステティックス インコーポレイテッド Temperature-dependent adhesion between applicator and skin during tissue cooling
US11229471B2 (en) 2016-01-15 2022-01-25 Cilag Gmbh International Modular battery powered handheld surgical instrument with selective application of energy based on tissue characterization
US11129670B2 (en) 2016-01-15 2021-09-28 Cilag Gmbh International Modular battery powered handheld surgical instrument with selective application of energy based on button displacement, intensity, or local tissue characterization
US10716615B2 (en) 2016-01-15 2020-07-21 Ethicon Llc Modular battery powered handheld surgical instrument with curved end effectors having asymmetric engagement between jaw and blade
US11051840B2 (en) 2016-01-15 2021-07-06 Ethicon Llc Modular battery powered handheld surgical instrument with reusable asymmetric handle housing
US10765552B2 (en) 2016-02-18 2020-09-08 Zeltiq Aesthetics, Inc. Cooling cup applicators with contoured heads and liner assemblies
US10555769B2 (en) 2016-02-22 2020-02-11 Ethicon Llc Flexible circuits for electrosurgical instrument
US10342566B2 (en) 2016-03-29 2019-07-09 Covidien Lp Devices, systems, and methods for cooling a surgical instrument
US10456156B2 (en) 2016-03-29 2019-10-29 Covidien Lp Devices, systems, and methods for cooling a surgical instrument
US10702329B2 (en) 2016-04-29 2020-07-07 Ethicon Llc Jaw structure with distal post for electrosurgical instruments
US10646269B2 (en) 2016-04-29 2020-05-12 Ethicon Llc Non-linear jaw gap for electrosurgical instruments
US10485607B2 (en) 2016-04-29 2019-11-26 Ethicon Llc Jaw structure with distal closure for electrosurgical instruments
US10456193B2 (en) 2016-05-03 2019-10-29 Ethicon Llc Medical device with a bilateral jaw configuration for nerve stimulation
US11382790B2 (en) 2016-05-10 2022-07-12 Zeltiq Aesthetics, Inc. Skin freezing systems for treating acne and skin conditions
US10555831B2 (en) 2016-05-10 2020-02-11 Zeltiq Aesthetics, Inc. Hydrogel substances and methods of cryotherapy
US10682297B2 (en) 2016-05-10 2020-06-16 Zeltiq Aesthetics, Inc. Liposomes, emulsions, and methods for cryotherapy
US11311327B2 (en) 2016-05-13 2022-04-26 Pacira Cryotech, Inc. Methods and systems for locating and treating nerves with cold therapy
US10245064B2 (en) 2016-07-12 2019-04-02 Ethicon Llc Ultrasonic surgical instrument with piezoelectric central lumen transducer
US10893883B2 (en) 2016-07-13 2021-01-19 Ethicon Llc Ultrasonic assembly for use with ultrasonic surgical instruments
US10842522B2 (en) 2016-07-15 2020-11-24 Ethicon Llc Ultrasonic surgical instruments having offset blades
US10376305B2 (en) 2016-08-05 2019-08-13 Ethicon Llc Methods and systems for advanced harmonic energy
US10285723B2 (en) 2016-08-09 2019-05-14 Ethicon Llc Ultrasonic surgical blade with improved heel portion
USD847990S1 (en) 2016-08-16 2019-05-07 Ethicon Llc Surgical instrument
US10828056B2 (en) 2016-08-25 2020-11-10 Ethicon Llc Ultrasonic transducer to waveguide acoustic coupling, connections, and configurations
US10952759B2 (en) 2016-08-25 2021-03-23 Ethicon Llc Tissue loading of a surgical instrument
US10603064B2 (en) 2016-11-28 2020-03-31 Ethicon Llc Ultrasonic transducer
US11266430B2 (en) 2016-11-29 2022-03-08 Cilag Gmbh International End effector control and calibration
US11076879B2 (en) 2017-04-26 2021-08-03 Zeltiq Aesthetics, Inc. Shallow surface cryotherapy applicators and related technology
US10820920B2 (en) 2017-07-05 2020-11-03 Ethicon Llc Reusable ultrasonic medical devices and methods of their use
KR101975258B1 (en) * 2017-10-17 2019-05-07 (주)휴러스트 Handpiece structure of harmonic scalpel for surgical operation
US11134998B2 (en) 2017-11-15 2021-10-05 Pacira Cryotech, Inc. Integrated cold therapy and electrical stimulation systems for locating and treating nerves and associated methods
US10881424B2 (en) 2018-02-13 2021-01-05 Covidien Lp Removable fluid reservoir and ultrasonic surgical instrument including the same
KR20210038661A (en) 2018-07-31 2021-04-07 젤티크 애스세틱스, 인코포레이티드. Methods, devices, and systems for improving skin properties
US11844563B2 (en) 2019-11-19 2023-12-19 Covidien Lp Energy-based surgical instruments incorporating cooling features
US11944366B2 (en) 2019-12-30 2024-04-02 Cilag Gmbh International Asymmetric segmented ultrasonic support pad for cooperative engagement with a movable RF electrode
US11937863B2 (en) 2019-12-30 2024-03-26 Cilag Gmbh International Deflectable electrode with variable compression bias along the length of the deflectable electrode
US11911063B2 (en) 2019-12-30 2024-02-27 Cilag Gmbh International Techniques for detecting ultrasonic blade to electrode contact and reducing power to ultrasonic blade
US11812957B2 (en) 2019-12-30 2023-11-14 Cilag Gmbh International Surgical instrument comprising a signal interference resolution system
US11786294B2 (en) 2019-12-30 2023-10-17 Cilag Gmbh International Control program for modular combination energy device
US11696776B2 (en) 2019-12-30 2023-07-11 Cilag Gmbh International Articulatable surgical instrument
US11744636B2 (en) 2019-12-30 2023-09-05 Cilag Gmbh International Electrosurgical systems with integrated and external power sources
US11452525B2 (en) 2019-12-30 2022-09-27 Cilag Gmbh International Surgical instrument comprising an adjustment system
US11779329B2 (en) 2019-12-30 2023-10-10 Cilag Gmbh International Surgical instrument comprising a flex circuit including a sensor system
US11950797B2 (en) 2019-12-30 2024-04-09 Cilag Gmbh International Deflectable electrode with higher distal bias relative to proximal bias
US11786291B2 (en) 2019-12-30 2023-10-17 Cilag Gmbh International Deflectable support of RF energy electrode with respect to opposing ultrasonic blade
US20210196361A1 (en) 2019-12-30 2021-07-01 Ethicon Llc Electrosurgical instrument with monopolar and bipolar energy capabilities
US11660089B2 (en) 2019-12-30 2023-05-30 Cilag Gmbh International Surgical instrument comprising a sensing system
US11937866B2 (en) 2019-12-30 2024-03-26 Cilag Gmbh International Method for an electrosurgical procedure
US11684412B2 (en) 2019-12-30 2023-06-27 Cilag Gmbh International Surgical instrument with rotatable and articulatable surgical end effector
US11779387B2 (en) 2019-12-30 2023-10-10 Cilag Gmbh International Clamp arm jaw to minimize tissue sticking and improve tissue control
US11633224B2 (en) 2020-02-10 2023-04-25 Icecure Medical Ltd. Cryogen pump

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4528979A (en) * 1982-03-18 1985-07-16 Kievsky Nauchno-Issledovatelsky Institut Otolaringologii Imeni Professora A.S. Kolomiiobenka Cryo-ultrasonic surgical instrument
US4832022A (en) * 1986-05-26 1989-05-23 Tomsky Gosudarstvenny Universitet Im. Kuibysheva Cryogenic ultrasonic scalpel
US6551309B1 (en) * 2000-09-14 2003-04-22 Cryoflex, Inc. Dual action cryoprobe and methods of using the same

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2334181A (en) * 1942-01-14 1943-11-16 Highway Safety Appliances Inc Valve for road sanding machines
GB998173A (en) 1963-02-04 1965-07-14 George Andrew Douglas Gordon Method and apparatus for destroying limited groups of cells
NL129743C (en) 1962-04-30 1900-01-01
NL145136C (en) 1967-07-25 1900-01-01
US4022215A (en) 1973-12-10 1977-05-10 Benson Jerrel W Cryosurgical system
US3889680A (en) 1974-02-07 1975-06-17 Armao T A Cryoadhesion preventing cryosurgical instruments
US4015606A (en) 1975-09-09 1977-04-05 Dynatech Corporation Method and means for controlling the freeze zone of a cryosurgical probe
SU1417868A1 (en) * 1985-11-20 1988-08-23 Томский государственный медицинский институт Cryoultrasonic scalpel
US5108390A (en) 1988-11-14 1992-04-28 Frigitronics, Inc. Flexible cryoprobe
GB2226497B (en) 1988-12-01 1992-07-01 Spembly Medical Ltd Cryosurgical probe
US4946460A (en) 1989-04-26 1990-08-07 Cryo Instruments, Inc. Apparatus for cryosurgery
ZA917281B (en) 1990-09-26 1992-08-26 Cryomedical Sciences Inc Cryosurgical instrument and system and method of cryosurgery
US5139496A (en) 1990-12-20 1992-08-18 Hed Aharon Z Ultrasonic freeze ablation catheters and probes
US5242449A (en) * 1991-04-23 1993-09-07 Allergan, Inc. Ophthalmic instrument
US5261399A (en) 1991-05-22 1993-11-16 Klatz Ronald M Brain cooling device and method for performing the same
US6030412A (en) 1991-05-22 2000-02-29 Life Science Holdings, Inc. Apparatus and method for cooling the brain, brain stem and associated neurologic tissues
US5520682A (en) 1991-09-06 1996-05-28 Cryomedical Sciences, Inc. Cryosurgical instrument with vent means and method using same
US5433717A (en) 1993-03-23 1995-07-18 The Regents Of The University Of California Magnetic resonance imaging assisted cryosurgery
US5452582A (en) 1994-07-06 1995-09-26 Apd Cryogenics, Inc. Cryo-probe
US5629936A (en) * 1994-08-01 1997-05-13 University Of Iowa Research Foundation Inc. Control of consecutive packet loss in a packet buffer
US5649936A (en) 1995-09-19 1997-07-22 Real; Douglas D. Stereotactic guide apparatus for use with neurosurgical headframe
US5716353A (en) 1996-05-03 1998-02-10 Urds, Corp. Cryosurgical instrument
US6039730A (en) 1996-06-24 2000-03-21 Allegheny-Singer Research Institute Method and apparatus for cryosurgery
US5800487A (en) 1996-07-23 1998-09-01 Endocare, Inc. Cryoprobe
US5916242A (en) 1996-11-04 1999-06-29 Schwartz; George R. Apparatus for rapid cooling of the brain and method of performing same
US5794629A (en) 1996-11-27 1998-08-18 The Regents Of The University Of California Method for treating ischemic brain stroke
US5910104A (en) 1996-12-26 1999-06-08 Cryogen, Inc. Cryosurgical probe with disposable sheath
US5899898A (en) 1997-02-27 1999-05-04 Cryocath Technologies Inc. Cryosurgical linear ablation
WO1998041156A1 (en) 1997-03-17 1998-09-24 Boris Rubinsky The use of cryoprotective agent compounds during cryosurgery
US6042579A (en) 1997-04-30 2000-03-28 Medtronic, Inc. Techniques for treating neurodegenerative disorders by infusion of nerve growth factors into the brain
US5906612A (en) 1997-09-19 1999-05-25 Chinn; Douglas O. Cryosurgical probe having insulating and heated sheaths
US6083166A (en) 1997-12-02 2000-07-04 Situs Corporation Method and apparatus for determining a measure of tissue manipulation
US6280441B1 (en) 1997-12-15 2001-08-28 Sherwood Services Ag Apparatus and method for RF lesioning
AU754269B2 (en) 1998-01-12 2002-11-07 Ronald P. Lesser Technique for using brain heat flow management to treat brain disorders
US6245095B1 (en) 1998-03-24 2001-06-12 Innercool Therapies, Inc. Method and apparatus for location and temperature specific drug action such as thrombolysis
US6096068A (en) 1998-01-23 2000-08-01 Innercool Therapies, Inc. Selective organ cooling catheter and method of using the same
US6051019A (en) 1998-01-23 2000-04-18 Del Mar Medical Technologies, Inc. Selective organ hypothermia method and apparatus
US6231595B1 (en) 1998-03-31 2001-05-15 Innercool Therapies, Inc. Circulating fluid hypothermia method and apparatus
US6045532A (en) 1998-02-20 2000-04-04 Arthrocare Corporation Systems and methods for electrosurgical treatment of tissue in the brain and spinal cord
US6106518A (en) 1998-04-09 2000-08-22 Cryocath Technologies, Inc. Variable geometry tip for a cryosurgical ablation device
US6126684A (en) 1998-04-21 2000-10-03 The Regents Of The University Of California Indwelling heat exchange catheter and method of using same
US6565565B1 (en) * 1998-06-17 2003-05-20 Howmedica Osteonics Corp. Device for securing spinal rods
US6217518B1 (en) 1998-10-01 2001-04-17 Situs Corporation Medical instrument sheath comprising a flexible ultrasound transducer
JP2003535615A (en) 1999-02-12 2003-12-02 コルパン，ニコライ Cryosurgical devices, especially for the treatment of tumors
US6546932B1 (en) 1999-04-05 2003-04-15 Cryocath Technologies Inc. Cryogenic method and apparatus for promoting angiogenesis
US6280439B1 (en) * 1999-07-12 2001-08-28 Cryocath Technologies, Inc. Adjustable position injection tubing
US6551337B1 (en) * 1999-10-05 2003-04-22 Omnisonics Medical Technologies, Inc. Ultrasonic medical device operating in a transverse mode
WO2001076517A2 (en) 2000-04-07 2001-10-18 The General Hospital Corporation D/B/A Massachusetts General Hospital Methods and apparatus for thermally affecting tissue
US6413263B1 (en) 2000-04-24 2002-07-02 Axon Instruments, Inc. Stereotactic probe holder and method of use
US6527765B2 (en) 2000-10-06 2003-03-04 Charles D. Kelman Cryogenic surgical system and method of use in removal of tissue
US6648880B2 (en) 2001-02-16 2003-11-18 Cryocath Technologies Inc. Method of using cryotreatment to treat brain tissue
US6478754B1 (en) 2001-04-23 2002-11-12 Advanced Medical Applications, Inc. Ultrasonic method and device for wound treatment
US6936045B2 (en) 2001-09-20 2005-08-30 Endocare, Inc. Malleable cryosurgical probe
US6858025B2 (en) 2002-08-06 2005-02-22 Medically Advanced Designs, Llc Cryo-surgical apparatus and method of use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4528979A (en) * 1982-03-18 1985-07-16 Kievsky Nauchno-Issledovatelsky Institut Otolaringologii Imeni Professora A.S. Kolomiiobenka Cryo-ultrasonic surgical instrument
US4832022A (en) * 1986-05-26 1989-05-23 Tomsky Gosudarstvenny Universitet Im. Kuibysheva Cryogenic ultrasonic scalpel
US6551309B1 (en) * 2000-09-14 2003-04-22 Cryoflex, Inc. Dual action cryoprobe and methods of using the same

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7943352B2 (en) 2006-03-29 2011-05-17 Bacoustics, Llc Apparatus and methods for vaccine development using ultrasound technology
US7846341B2 (en) 2006-12-04 2010-12-07 Bacoustics, Llc Method of ultrasonically treating a continuous flow of fluid
US8016208B2 (en) 2008-02-08 2011-09-13 Bacoustics, Llc Echoing ultrasound atomization and mixing system
US7830070B2 (en) 2008-02-12 2010-11-09 Bacoustics, Llc Ultrasound atomization system

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