WO2007059149A3 - Scutellaria barbata extract for the treatment of cancer - Google Patents

Scutellaria barbata extract for the treatment of cancer Download PDF

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Publication number
WO2007059149A3
WO2007059149A3 PCT/US2006/044224 US2006044224W WO2007059149A3 WO 2007059149 A3 WO2007059149 A3 WO 2007059149A3 US 2006044224 W US2006044224 W US 2006044224W WO 2007059149 A3 WO2007059149 A3 WO 2007059149A3
Authority
WO
WIPO (PCT)
Prior art keywords
scutellaria barbata
extract
cancer
treatment
cancers
Prior art date
Application number
PCT/US2006/044224
Other languages
French (fr)
Other versions
WO2007059149A2 (en
Inventor
Isaac Cohen
Original Assignee
Bionovo Inc
Isaac Cohen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bionovo Inc, Isaac Cohen filed Critical Bionovo Inc
Priority to GB0810224A priority Critical patent/GB2448249A/en
Priority to CA002629638A priority patent/CA2629638A1/en
Priority to JP2008541285A priority patent/JP2009515977A/en
Priority to AU2006315459A priority patent/AU2006315459A1/en
Priority to EP06837591A priority patent/EP1965819A4/en
Publication of WO2007059149A2 publication Critical patent/WO2007059149A2/en
Publication of WO2007059149A3 publication Critical patent/WO2007059149A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

An extract of Scutellaria barbata D. Don is effective in the arrest of cancer cell growth in the Gl phase, the induction of apoptosis in cancer cells and the shrinking of solid cancers. The extract may be prepared as a pharmaceutical composition for administration to mammals for the treatment of solid cancers, such as epithelial cancers. Such epithelial cancers include breast cancer and ovarian cancers. The extract is obtained from Scutellaria barbata D. Don by contacting aerial portions of a plant from the species Scutellaria barbata D. Don with an aqueous or alcoholic solvent.
PCT/US2006/044224 2005-11-14 2006-11-14 Scutellaria barbata extract for the treatment of cancer WO2007059149A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
GB0810224A GB2448249A (en) 2005-11-14 2006-11-14 Scutellaria barbata extract for the treatment of cancer
CA002629638A CA2629638A1 (en) 2005-11-14 2006-11-14 Scutellaria barbata extract for the treatment of cancer
JP2008541285A JP2009515977A (en) 2005-11-14 2006-11-14 Scutellaria barbata extract for the treatment of cancer
AU2006315459A AU2006315459A1 (en) 2005-11-14 2006-11-14 Scutellaria barbata extract for the treatment of cancer
EP06837591A EP1965819A4 (en) 2005-11-14 2006-11-14 Scutellaria barbata extract for the treatment of cancer

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US73662005P 2005-11-14 2005-11-14
US60/736,620 2005-11-14
US11/559,324 US7700136B2 (en) 2005-11-14 2006-11-13 Scutellaria barbata extract for the treatment of cancer
US11/559,324 2006-11-13

Publications (2)

Publication Number Publication Date
WO2007059149A2 WO2007059149A2 (en) 2007-05-24
WO2007059149A3 true WO2007059149A3 (en) 2008-01-24

Family

ID=38041130

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/044224 WO2007059149A2 (en) 2005-11-14 2006-11-14 Scutellaria barbata extract for the treatment of cancer

Country Status (7)

Country Link
US (2) US7700136B2 (en)
EP (1) EP1965819A4 (en)
JP (1) JP2009515977A (en)
AU (1) AU2006315459A1 (en)
CA (1) CA2629638A1 (en)
GB (2) GB2448249A (en)
WO (1) WO2007059149A2 (en)

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AU2008329902A1 (en) * 2007-11-19 2009-06-04 Bionovo, Inc. A process of making purified extract of scutellaria barbata D. Don
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JP2012501974A (en) * 2008-09-03 2012-01-26 バイオノボ・インコーポレーテッド Methods and compositions for the treatment of cancer
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Also Published As

Publication number Publication date
CA2629638A1 (en) 2007-05-24
GB0808665D0 (en) 2008-06-18
GB2448249A (en) 2008-10-08
US7700136B2 (en) 2010-04-20
EP1965819A4 (en) 2011-03-23
AU2006315459A1 (en) 2007-05-24
US20100143511A1 (en) 2010-06-10
EP1965819A2 (en) 2008-09-10
US20070110832A1 (en) 2007-05-17
GB0810224D0 (en) 2008-07-09
WO2007059149A2 (en) 2007-05-24
JP2009515977A (en) 2009-04-16

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