WO2007070642A3 - Methods for increasing accuracy of nucleic acid sequencing - Google Patents

Methods for increasing accuracy of nucleic acid sequencing Download PDF

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Publication number
WO2007070642A3
WO2007070642A3 PCT/US2006/047739 US2006047739W WO2007070642A3 WO 2007070642 A3 WO2007070642 A3 WO 2007070642A3 US 2006047739 W US2006047739 W US 2006047739W WO 2007070642 A3 WO2007070642 A3 WO 2007070642A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
methods
acid sequencing
increasing accuracy
sequencing
Prior art date
Application number
PCT/US2006/047739
Other languages
French (fr)
Other versions
WO2007070642A2 (en
Inventor
Eric G Lander
Stanley N Lapidus
Original Assignee
Helicos Biosciences Corp
Eric G Lander
Stanley N Lapidus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helicos Biosciences Corp, Eric G Lander, Stanley N Lapidus filed Critical Helicos Biosciences Corp
Priority to US12/097,023 priority Critical patent/US20090305248A1/en
Publication of WO2007070642A2 publication Critical patent/WO2007070642A2/en
Publication of WO2007070642A3 publication Critical patent/WO2007070642A3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing

Abstract

The invention provides methods for improving the fidelity of a sequencing-by-synthesis reaction by resequencing at least a portion of a nucleic acid template.
PCT/US2006/047739 2005-12-15 2006-12-15 Methods for increasing accuracy of nucleic acid sequencing WO2007070642A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/097,023 US20090305248A1 (en) 2005-12-15 2006-12-15 Methods for increasing accuracy of nucleic acid sequencing

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30304605A 2005-12-15 2005-12-15
US11/303,046 2005-12-15

Publications (2)

Publication Number Publication Date
WO2007070642A2 WO2007070642A2 (en) 2007-06-21
WO2007070642A3 true WO2007070642A3 (en) 2008-08-21

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/047739 WO2007070642A2 (en) 2005-12-15 2006-12-15 Methods for increasing accuracy of nucleic acid sequencing

Country Status (2)

Country Link
US (1) US20090305248A1 (en)
WO (1) WO2007070642A2 (en)

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US8551704B2 (en) 2007-02-16 2013-10-08 Pacific Biosciences Of California, Inc. Controllable strand scission of mini circle DNA
AU2008282862B2 (en) * 2007-07-26 2014-07-31 Pacific Biosciences Of California, Inc. Molecular redundant sequencing
US8617811B2 (en) 2008-01-28 2013-12-31 Complete Genomics, Inc. Methods and compositions for efficient base calling in sequencing reactions
WO2009073629A2 (en) * 2007-11-29 2009-06-11 Complete Genomics, Inc. Efficient shotgun sequencing methods
MX2010010600A (en) 2008-03-28 2011-03-30 Pacific Biosciences California Inc Compositions and methods for nucleic acid sequencing.
US8628940B2 (en) 2008-09-24 2014-01-14 Pacific Biosciences Of California, Inc. Intermittent detection during analytical reactions
US8236499B2 (en) 2008-03-28 2012-08-07 Pacific Biosciences Of California, Inc. Methods and compositions for nucleic acid sample preparation
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US8383369B2 (en) 2008-09-24 2013-02-26 Pacific Biosciences Of California, Inc. Intermittent detection during analytical reactions
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WO2007070642A2 (en) 2007-06-21
US20090305248A1 (en) 2009-12-10

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