WO2007078821A3 - Method and apparatus for acquiring high resolution spectral data or high definition images in inhomogeneous environments - Google Patents

Method and apparatus for acquiring high resolution spectral data or high definition images in inhomogeneous environments Download PDF

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Publication number
WO2007078821A3
WO2007078821A3 PCT/US2006/047689 US2006047689W WO2007078821A3 WO 2007078821 A3 WO2007078821 A3 WO 2007078821A3 US 2006047689 W US2006047689 W US 2006047689W WO 2007078821 A3 WO2007078821 A3 WO 2007078821A3
Authority
WO
WIPO (PCT)
Prior art keywords
sample
magnetic field
high resolution
spectral data
definition images
Prior art date
Application number
PCT/US2006/047689
Other languages
French (fr)
Other versions
WO2007078821A2 (en
Inventor
Lucio Frydman
Boaz Shapira
Assaf Tal
Original Assignee
Yeda Res & Dev
Fleit Lois
Lucio Frydman
Boaz Shapira
Assaf Tal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev, Fleit Lois, Lucio Frydman, Boaz Shapira, Assaf Tal filed Critical Yeda Res & Dev
Priority to US12/158,364 priority Critical patent/US7944206B2/en
Priority to EP06845404.0A priority patent/EP1963830A4/en
Publication of WO2007078821A2 publication Critical patent/WO2007078821A2/en
Priority to IL192363A priority patent/IL192363A0/en
Publication of WO2007078821A3 publication Critical patent/WO2007078821A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/565—Correction of image distortions, e.g. due to magnetic field inhomogeneities
    • G01R33/56563—Correction of image distortions, e.g. due to magnetic field inhomogeneities caused by a distortion of the main magnetic field B0, e.g. temporal variation of the magnitude or spatial inhomogeneity of B0
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/4818—MR characterised by data acquisition along a specific k-space trajectory or by the temporal order of k-space coverage, e.g. centric or segmented coverage of k-space
    • G01R33/482—MR characterised by data acquisition along a specific k-space trajectory or by the temporal order of k-space coverage, e.g. centric or segmented coverage of k-space using a Cartesian trajectory
    • G01R33/4822—MR characterised by data acquisition along a specific k-space trajectory or by the temporal order of k-space coverage, e.g. centric or segmented coverage of k-space using a Cartesian trajectory in three dimensions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/483—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
    • G01R33/485—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy based on chemical shift information [CSI] or spectroscopic imaging, e.g. to acquire the spatial distributions of metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/561—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by reduction of the scanning time, i.e. fast acquiring systems, e.g. using echo-planar pulse sequences
    • G01R33/5615—Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/561—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by reduction of the scanning time, i.e. fast acquiring systems, e.g. using echo-planar pulse sequences
    • G01R33/5615—Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE]
    • G01R33/5616—Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE] using gradient refocusing, e.g. EPI
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/561—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution by reduction of the scanning time, i.e. fast acquiring systems, e.g. using echo-planar pulse sequences
    • G01R33/5615—Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE]
    • G01R33/5617—Echo train techniques involving acquiring plural, differently encoded, echo signals after one RF excitation, e.g. using gradient refocusing in echo planar imaging [EPI], RF refocusing in rapid acquisition with relaxation enhancement [RARE] or using both RF and gradient refocusing in gradient and spin echo imaging [GRASE] using RF refocusing, e.g. RARE

Abstract

A method and apparatus for treating a sample for acquiring high-definition magnetic resonance images, (MRI images) or high resolution nuclear magnetic resonance (NMR) spectra even in the presence of magnetic field distortions within one or multiple scans The spatial nature and temporal dependence of the field inhomogeneities are determined a pnori using any of several literature procedures A static or oscillating magnetic field gradient is applie d on the sample so as to endow spins at different positions within the sample with different resonance frequencies A phase- and amplitude-modulated radiofrequency (RF) pulse is applied in unison with the magnetic field gradient so as to endow spins a t different positions within the sample with a homogeneous excitation/inversion profile
PCT/US2006/047689 2005-12-21 2006-12-14 Method and apparatus for acquiring high resolution spectral data or high definition images in inhomogeneous environments WO2007078821A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US12/158,364 US7944206B2 (en) 2005-12-21 2006-12-14 Method and apparatus for acquiring high resolution spectral data or high definition images in inhomogeneous environments
EP06845404.0A EP1963830A4 (en) 2005-12-21 2006-12-14 Method and apparatus for acquiring high resolution spectral data or high definition images in inhomogeneous environments
IL192363A IL192363A0 (en) 2005-12-21 2008-06-22 Method and apparatus for acquiring high resolution spectral data or high definition images in inhomogeneous environments

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US75248905P 2005-12-21 2005-12-21
US60/752,489 2005-12-21
US79952706P 2006-05-11 2006-05-11
US60/799,527 2006-05-11

Publications (2)

Publication Number Publication Date
WO2007078821A2 WO2007078821A2 (en) 2007-07-12
WO2007078821A3 true WO2007078821A3 (en) 2008-11-27

Family

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Family Applications (1)

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PCT/US2006/047689 WO2007078821A2 (en) 2005-12-21 2006-12-14 Method and apparatus for acquiring high resolution spectral data or high definition images in inhomogeneous environments

Country Status (4)

Country Link
US (1) US7944206B2 (en)
EP (1) EP1963830A4 (en)
IL (1) IL192363A0 (en)
WO (1) WO2007078821A2 (en)

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WO2009102874A2 (en) * 2008-02-12 2009-08-20 The Research Foundation Of State University Of New York Methods of using combined forward and backward sampling of nuclear magnetic resonance time domain for measurement of secondary phase shifts, detection of absorption mode signals devoid of dispersive components, and/or optimization of nuclear magnetic resonance experiments
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US8085046B2 (en) * 2008-08-28 2011-12-27 The General Hospital Corporation Coil array mode compression for parallel transmission magnetic resonance imaging
JP2010207568A (en) * 2009-02-10 2010-09-24 Toshiba Corp Magnetic resonance imaging apparatus
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WO2012050901A2 (en) * 2010-09-28 2012-04-19 The Regents Of The University Of Colorado, A Body Corporate Fourier domain sensing
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DE102012208425B4 (en) * 2012-05-21 2013-12-12 Siemens Aktiengesellschaft Continuously correct phase errors of a multidimensional, site-selective magnetic resonance measurement sequence
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US9316711B2 (en) * 2012-08-07 2016-04-19 Wisconsin Alumni Research Foundation System and method for accelerated magnetic resonance imaging using spectral sensitivity
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WO2015164709A1 (en) * 2014-04-24 2015-10-29 Regents Of The University Of Minnesota Systems and methods for multiband sweep imaging with fourier transformation
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US9891300B2 (en) * 2014-08-21 2018-02-13 University Of Virginia Patent Foundation Method and apparatus for acquiring magnetic resonance data
JP2018520730A (en) * 2015-05-29 2018-08-02 メイヨ フォンデーシヨン フォー メディカル エジュケーション アンド リサーチ System and method for compensatory magnetic field correction in magnetic resonance imaging using asymmetric gradients
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CN107015181B (en) * 2017-04-07 2020-01-14 厦门大学 Method for measuring proton longitudinal relaxation time under inhomogeneous magnetic field
KR101980893B1 (en) * 2017-11-10 2019-08-28 성균관대학교산학협력단 Device and method for dynamic tagged magnet resonance imaging
CN108169273B (en) * 2017-12-28 2020-04-21 厦门大学 Two-dimensional magnetic resonance single voxel localized J decomposition spectrum method for realizing pure absorption line type
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Also Published As

Publication number Publication date
US20100001727A1 (en) 2010-01-07
WO2007078821A2 (en) 2007-07-12
US7944206B2 (en) 2011-05-17
EP1963830A4 (en) 2013-04-24
IL192363A0 (en) 2008-12-29
EP1963830A2 (en) 2008-09-03

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