WO2007084976A3 - Methods of detection of iron deficiency - Google Patents

Methods of detection of iron deficiency Download PDF

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Publication number
WO2007084976A3
WO2007084976A3 PCT/US2007/060752 US2007060752W WO2007084976A3 WO 2007084976 A3 WO2007084976 A3 WO 2007084976A3 US 2007060752 W US2007060752 W US 2007060752W WO 2007084976 A3 WO2007084976 A3 WO 2007084976A3
Authority
WO
WIPO (PCT)
Prior art keywords
detection
iron deficiency
methods
mean cell
mch
Prior art date
Application number
PCT/US2007/060752
Other languages
French (fr)
Other versions
WO2007084976A2 (en
Inventor
Robert T Magari
Ramon Simon-Lopez
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Priority to JP2008551541A priority Critical patent/JP4925364B2/en
Priority to EP07717317A priority patent/EP2016423B1/en
Publication of WO2007084976A2 publication Critical patent/WO2007084976A2/en
Publication of WO2007084976A3 publication Critical patent/WO2007084976A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/22—Haematology
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]

Abstract

New diagnostic indexes and the method of use for detection of iron deficiency have been disclosed. These include a logistic function of mean cell hemoglobin (MCH) and mean cell volume (MCV), and a logistic function of mean cell hemoglobin concentration (MCHC) and MCH.
PCT/US2007/060752 2006-01-20 2007-01-19 Methods of detection of iron deficiency WO2007084976A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2008551541A JP4925364B2 (en) 2006-01-20 2007-01-19 How to detect iron deficiency
EP07717317A EP2016423B1 (en) 2006-01-20 2007-01-19 Methods of detection of iron deficiency

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76052006P 2006-01-20 2006-01-20
US60/760,520 2006-01-20

Publications (2)

Publication Number Publication Date
WO2007084976A2 WO2007084976A2 (en) 2007-07-26
WO2007084976A3 true WO2007084976A3 (en) 2008-03-27

Family

ID=38288401

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2007/060753 WO2007084977A2 (en) 2006-01-20 2007-01-19 Low hemoglobin concentration cell percentage and method of use in detection of iron deficiency
PCT/US2007/060752 WO2007084976A2 (en) 2006-01-20 2007-01-19 Methods of detection of iron deficiency

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2007/060753 WO2007084977A2 (en) 2006-01-20 2007-01-19 Low hemoglobin concentration cell percentage and method of use in detection of iron deficiency

Country Status (4)

Country Link
US (2) US7361510B2 (en)
EP (2) EP1976541B1 (en)
JP (3) JP4822562B2 (en)
WO (2) WO2007084977A2 (en)

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US7960343B2 (en) 2007-09-18 2011-06-14 Acceleron Pharma Inc. Activin-ActRIIa antagonists and uses for decreasing or inhibiting FSH secretion
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US8058229B2 (en) 2008-08-14 2011-11-15 Acceleron Pharma Inc. Method of increasing red blood cell levels or treating anemia in a patient
WO2010054180A1 (en) * 2008-11-07 2010-05-14 Beckman Coulter, Inc. High sensitivity parameters for the detection of vitamin b12 and/or folate deficiencies and methods of use
CA2749544A1 (en) 2009-01-13 2010-07-22 Acceleron Pharma Inc. Methods for increasing adiponectin
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US8178488B2 (en) 2009-06-08 2012-05-15 Acceleron Pharma, Inc. Methods for increasing thermogenic adipocytes
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ES2869580T3 (en) * 2009-09-09 2021-10-25 Acceleron Pharma Inc ActRIIB antagonists and dosage and uses thereof for treating obesity or type 2 diabetes by regulating body fat content
EP2496247B1 (en) * 2009-11-03 2017-08-23 Acceleron Pharma, Inc. Methods for treating fatty liver disease
AU2010322011B2 (en) * 2009-11-17 2016-03-31 Acceleron Pharma Inc. ActRIIB proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy
US8906308B2 (en) * 2010-01-15 2014-12-09 Abbott Laboratories Method for determining volume and hemoglobin content of individual red blood cells
JP5782318B2 (en) * 2010-07-16 2015-09-24 住友化学株式会社 Composition containing polymer compound and light emitting device using the same
JP5868982B2 (en) * 2010-09-16 2016-02-24 ザ ジェネラル ホスピタル コーポレイション Red blood cell dynamics for diagnosis
JP2014502260A (en) 2010-11-08 2014-01-30 アクセルロン ファーマ， インコーポレイテッド ACTRIIA binders and uses thereof
CN103827658B (en) * 2011-07-22 2016-04-13 罗氏血液诊断股份有限公司 Identify and measure desmacyte
RU2018145985A (en) 2012-11-02 2019-02-18 Селджин Корпорейшн ACTIVIN-ACTRII ANTAGONISTS AND THEIR APPLICATION FOR TREATMENT OF BONE TISSUE DISORDERS AND OTHER DISORDERS
EP3152322B1 (en) * 2014-06-05 2019-09-11 The General Hospital Corporation Estimating risk of death using the clearance volume of red blood cells as biomarker
BR122023023170A2 (en) 2014-06-13 2024-02-20 Acceleron Pharma Inc. USE OF AN ACTRII ANTAGONIST IN THE TREATMENT OR PREVENTION OF SKIN ULCERS ASSOCIATED WITH BETA-THALASSEMIA
MA41052A (en) 2014-10-09 2017-08-15 Celgene Corp TREATMENT OF CARDIOVASCULAR DISEASE USING ACTRII LIGAND TRAPS
IL252631B1 (en) 2014-12-03 2024-02-01 Celgene Corp Activin-actrii antagonists and uses for treating anemia
JP6952683B2 (en) 2015-09-17 2021-10-20 エス．ディー．サイト ダイアグノスティクス リミテッド Methods and devices for detecting entities in body samples
US10955423B2 (en) 2015-12-15 2021-03-23 The General Hospital Corporation Methods of estimating blood glucose and related systems
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US11293852B2 (en) 2016-04-07 2022-04-05 The General Hospital Corporation White blood cell population dynamics
AU2017263807B2 (en) * 2016-05-11 2023-02-02 S.D. Sight Diagnostics Ltd Performing optical measurements on a sample
WO2017195205A1 (en) 2016-05-11 2017-11-16 S.D. Sight Diagnostics Ltd Sample carrier for optical measurements
US11921272B2 (en) 2017-11-14 2024-03-05 S.D. Sight Diagnostics Ltd. Sample carrier for optical measurements
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Also Published As

Publication number Publication date
JP2009524069A (en) 2009-06-25
JP4822562B2 (en) 2011-11-24
EP1976541A2 (en) 2008-10-08
WO2007084977A3 (en) 2007-11-29
WO2007084976A2 (en) 2007-07-26
EP1976541B1 (en) 2011-07-13
JP2012042488A (en) 2012-03-01
JP2009524068A (en) 2009-06-25
EP1976541A4 (en) 2010-03-03
JP4925364B2 (en) 2012-04-25
US20070172955A1 (en) 2007-07-26
EP2016423A2 (en) 2009-01-21
JP5592339B2 (en) 2014-09-17
EP2016423B1 (en) 2011-07-13
US7361512B2 (en) 2008-04-22
WO2007084977A2 (en) 2007-07-26
US7361510B2 (en) 2008-04-22
US20070172956A1 (en) 2007-07-26
EP2016423A4 (en) 2010-03-03

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