WO2007095193A3 - Scaffolds for organ reconstruction and augmentation - Google Patents

Scaffolds for organ reconstruction and augmentation Download PDF

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Publication number
WO2007095193A3
WO2007095193A3 PCT/US2007/003709 US2007003709W WO2007095193A3 WO 2007095193 A3 WO2007095193 A3 WO 2007095193A3 US 2007003709 W US2007003709 W US 2007003709W WO 2007095193 A3 WO2007095193 A3 WO 2007095193A3
Authority
WO
WIPO (PCT)
Prior art keywords
scaffolds
organ
augmentation
patient
seeded
Prior art date
Application number
PCT/US2007/003709
Other languages
French (fr)
Other versions
WO2007095193A2 (en
Inventor
Timothy A Bertram
Andrew Bruce
Deepak Jain
Manuel Jayo
John Ludlow
Darrell Mccoy
Richard Payne
Namrata Sangha
Original Assignee
Tengion Inc
Timothy A Bertram
Andrew Bruce
Deepak Jain
Manuel Jayo
John Ludlow
Darrell Mccoy
Richard Payne
Namrata Sangha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tengion Inc, Timothy A Bertram, Andrew Bruce, Deepak Jain, Manuel Jayo, John Ludlow, Darrell Mccoy, Richard Payne, Namrata Sangha filed Critical Tengion Inc
Priority to JP2008554417A priority Critical patent/JP5416415B2/en
Priority to EP07750540A priority patent/EP1987134A4/en
Priority to CA2641733A priority patent/CA2641733C/en
Publication of WO2007095193A2 publication Critical patent/WO2007095193A2/en
Publication of WO2007095193A3 publication Critical patent/WO2007095193A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/042—Urinary bladders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3813—Epithelial cells, e.g. keratinocytes, urothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3826—Muscle cells, e.g. smooth muscle cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/383—Nerve cells, e.g. dendritic cells, Schwann cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3882—Hollow organs, e.g. bladder, esophagus, urether, uterus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3886—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types
    • A61L27/3891—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells comprising two or more cell types as distinct cell layers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0697—Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2002/047—Urethrae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2002/048—Ureters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1347—Smooth muscle cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/25—Urinary tract cells, renal cells
    • C12N2502/253—Bladder cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/40—Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers

Abstract

Biocompatible synthetic or natural scaffolds are provided for the reconstruction, repair, augmentation or replacement of organs or tissue structures in a patient in need of such treatment. The scaffolds are shaped to conform to at least a part of the organ or tissue structure and may be seeded with one or more cell populations. Inserts, receptacles and ports are also provided for the attachment of tubular vessels to the neo-organ scaffolds. The seeded scaffolds are implanted into the patient at the site in need of treatment to form an organized organ or tissue structure. The scaffolds may be used to form organs or tissues, such as bladders, urethras, valves, and blood vessels.
PCT/US2007/003709 2006-02-10 2007-02-12 Scaffolds for organ reconstruction and augmentation WO2007095193A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2008554417A JP5416415B2 (en) 2006-02-10 2007-02-12 Skeleton for organ reconstruction and augmentation
EP07750540A EP1987134A4 (en) 2006-02-10 2007-02-12 Scaffolds for organ reconstruction and augmentation
CA2641733A CA2641733C (en) 2006-02-10 2007-02-12 Scaffolds for organ reconstruction and augmentation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77275406P 2006-02-10 2006-02-10
US60/772,754 2006-02-10

Publications (2)

Publication Number Publication Date
WO2007095193A2 WO2007095193A2 (en) 2007-08-23
WO2007095193A3 true WO2007095193A3 (en) 2008-11-20

Family

ID=38372067

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/003709 WO2007095193A2 (en) 2006-02-10 2007-02-12 Scaffolds for organ reconstruction and augmentation

Country Status (5)

Country Link
US (3) US7918897B2 (en)
EP (1) EP1987134A4 (en)
JP (3) JP5416415B2 (en)
CA (2) CA2641733C (en)
WO (1) WO2007095193A2 (en)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4057781B2 (en) * 1997-10-31 2008-03-05 チルドレンズ メディカル センター コーポレーション Bladder reconstruction
CA2472184C (en) * 2002-01-14 2011-04-19 David Mark Lucas Magnetically detectable latex articles
US9788821B2 (en) * 2005-04-29 2017-10-17 Cook Biotech Incorporated Physically modified extracellular matrix materials and uses thereof
US7846728B2 (en) * 2006-10-13 2010-12-07 BioStruxs, LLC Tissue engineering in vivo with vascularized scaffolds
US8658851B2 (en) * 2006-10-20 2014-02-25 Keracure, Inc. Devices with cells cultured on flexible supports
JP2010523268A (en) 2007-04-12 2010-07-15 ザ ジェネラル ホスピタル コーポレーション Biomimetic vascular network and device using the same
US20100070020A1 (en) 2008-06-11 2010-03-18 Nanovasc, Inc. Implantable Medical Device
US20090069904A1 (en) * 2007-09-12 2009-03-12 Applied Medical Research Biomaterial including micropores
JP5632749B2 (en) * 2008-02-14 2014-11-26 テンジオン， インコーポレイテッド Tissue engineering scaffold
US20130116799A1 (en) 2008-03-27 2013-05-09 The Cleveland Clinic Foundation Reinforced tissue graft
WO2009120966A2 (en) * 2008-03-27 2009-10-01 The Cleveland Clinic Foundation Reinforced tissue graft
EP2300495A4 (en) * 2008-06-11 2011-08-03 Childrens Mercy Hospital Solutions for tissue engineering and methods of use
US20090318934A1 (en) * 2008-06-20 2009-12-24 Johnson Chad E Compressible/expandable medical graft products, and methods for applying hemostasis
KR20190067267A (en) * 2008-11-04 2019-06-14 인리젠 Cell-scaffold constructs
KR102357077B1 (en) 2008-11-12 2022-01-27 인리젠 Isolated renal cells and uses thereof
WO2010093333A1 (en) * 2009-02-11 2010-08-19 Nanyang Technological University Multi-layered surgical prosthesis
JP5662427B2 (en) 2009-06-04 2015-01-28 ローテーション メディカル インコーポレイテッドＲｏｔａｔｉｏｎ Ｍｅｄｉｃａｌ，Ｉｎｃ． Device for fixing a sheet-like material to a target tissue
US8758447B2 (en) * 2009-06-30 2014-06-24 Ethicon, Inc. Device and method for repair of urological structures
US20100331963A1 (en) * 2009-06-30 2010-12-30 Jackie Donners Method of Making Suture-Less Hollow Scaffolds
US20110224800A1 (en) * 2010-03-09 2011-09-15 Ludlow John W Cell-scaffold constructs
WO2011137394A1 (en) * 2010-04-29 2011-11-03 BioStruxs, LLC Breast reconstruction device and methods
KR20190018737A (en) 2010-05-03 2019-02-25 인리젠 Smooth Muscle Cell Constructs
DE112011101571A5 (en) * 2010-05-06 2013-02-21 Otto-Von-Guericke-Universität Magdeburg Medizinische Fakultät Urinary bladder prosthesis for subcutaneous implantation
US10077442B2 (en) 2010-05-12 2018-09-18 Inregen Bioactive renal cells
US9668846B2 (en) 2010-05-24 2017-06-06 Drexel University Textile-templated electrospun anisotropic scaffolds for tissue engineering and regenerative medicine
WO2011156642A1 (en) 2010-06-11 2011-12-15 Tengion, Inc. Erythropoietin-expressing adipose cell populations
TWI607757B (en) 2010-11-10 2017-12-11 英瑞金公司 Therapeutic formulations
ES2935399T3 (en) 2011-01-06 2023-03-06 Humacyte Inc Constructs generated by tissue engineering
US8597948B2 (en) * 2011-03-10 2013-12-03 First Principles, Inc. Cloned biological material medical device and method thereof
ITMI20110386A1 (en) * 2011-03-11 2012-09-12 Antonio Sambusseti HEAVY-DUTY HEADSET FOR VESCICALE ENLARGEMENT IN LOW COMPLIANCE PATIENTS
ITMI20110387A1 (en) * 2011-03-11 2012-09-12 Antonio Sambusseti HEMISPHERE FOR VESICAL ENLARGEMENT IN PATIENTS WITH LOW COMPLIANCE
PL2773955T3 (en) 2011-11-04 2018-12-31 Inregen Drug screening and potency assays
ITMI20120381A1 (en) * 2012-03-12 2013-09-13 Antonio Sambusseti REINFORTABLE PGA PATCH REINFORCED FOR REPLACEMENT OF A VESCICAL WALL PORTION FOLLOWED BY PARTIAL VESCITECTOMY
ITMI20120380A1 (en) 2012-03-12 2013-09-13 Antonio Sambusseti HEAVY-DUTY HEADSET IMPROVED FOR VESCICALE ENLARGEMENT IN PATIENTS WITH LOW COMPLIANCE OR FOR THE REPLACEMENT OF A WIDER PORTION OF BLIND FOLLOWING BILARZIA
WO2013148264A1 (en) * 2012-03-30 2013-10-03 University Of Rochester Controlling extracellular matrix protein microstructure with ultrasound
WO2013151725A1 (en) 2012-04-05 2013-10-10 The Regents Of The University Of California Regenerative sera cells and mesenchymal stem cells
ITMI20121555A1 (en) * 2012-09-19 2014-03-20 Gianni Cancarini ORTHOTOPIC ENDOPROSTHESIS OF ARTIFICIAL BLADDER
US10952806B2 (en) 2012-09-25 2021-03-23 Axogen Corporation Materials and methods for protecting against neuromas
EP2900292B1 (en) * 2012-09-25 2020-07-22 AxoGen Corporation Materials and methods for protecting against neuromas
ITMI20121743A1 (en) 2012-10-16 2014-04-17 Gianni Cancarini ORTHOTOPIC ENDOPROSTHESIS OF ARTIFICIAL BLADDER
KR102160725B1 (en) 2012-10-24 2020-09-29 인리젠 Renal cell populations and uses thereof
ITMI20121809A1 (en) * 2012-10-24 2014-04-25 Antonio Sambusseti ANASTOMOSIS SYSTEM FOR A Bladder ENDOPROSTHESIS
KR102349183B1 (en) 2013-05-08 2022-01-07 인리젠 Organoids comprising isolated renal cells and uses thereof
ITMI20130799A1 (en) * 2013-05-15 2014-11-16 Antonio Sambusseti ORTHOTOPIC ENDOPROSTHESIS OF ARTIFICIAL BLADDER WITH IMPROVED ANTI-FLUX PROPERTIES
CN103393482B (en) * 2013-08-14 2016-04-06 北京瑞健高科生物科技有限公司 A kind of mammary prostheses supporting device based on tissue matrix material and preparation method thereof
ITMI20132071A1 (en) * 2013-12-12 2015-06-13 Gianni Cancarini ORTHOTOPIC ENDOPROSTHESIS OF ARTIFICIAL BLADDER
AU2015229457B2 (en) 2014-03-11 2018-11-22 Manufacturing Resources International, Inc. Hybrid Rear Cover and Mounting Bracket for Electronic Display
CN106163450A (en) * 2014-04-14 2016-11-23 安东尼奥·桑布瑟蒂 Prosthese in Orthotopic artificial bladder
EP3200722A1 (en) * 2014-09-30 2017-08-09 Antonio Sambusseti Orthotopic artificial bladder endoprosthesis
BR112017006557A2 (en) 2014-09-30 2018-01-23 sambusseti Antonio orthotopic artificial bladder stent graft
FR3045664A1 (en) * 2015-12-17 2017-06-23 Oreal MEMBRANE FOR RECONSTRUCTED FABRIC COMPRISING PORES OF SEVERAL DIAMETERS
US10646616B2 (en) * 2016-04-28 2020-05-12 National University Corporation Nagoya Institute Of Technology Method for manufacturing bone-regeneration material comprising biodegradable fibers by using electrospinning method
US9750591B1 (en) 2016-07-29 2017-09-05 Sam Sultan Systems and methods for assisting patients in emptying their bladder efficiently
US11123372B2 (en) 2016-07-29 2021-09-21 Prokidney Bioactive renal cells for the treatment of chronic kidney disease
KR20230104734A (en) * 2017-04-25 2023-07-10 옥소젠 코포레이션 Materials and methods for protecting against neuromas
WO2019070960A1 (en) * 2017-10-04 2019-04-11 Sampaio Luiz C Artificial blood barrier
WO2020070694A1 (en) * 2018-10-03 2020-04-09 Establishment Labs S.A. Scaffolding for implantable medical devices and methods of use thereof
JP7341047B2 (en) * 2019-12-25 2023-09-08 株式会社荏原製作所 Antimony adsorbent and antimony-containing liquid treatment equipment and treatment method
CN113384379B (en) * 2021-06-17 2022-12-02 深圳华越再生医学生物科技有限公司 For wrapping device for transplanting visceral organs

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6296668B1 (en) * 1997-02-14 2001-10-02 Assistance Publique-Hopitaux De Paris Artificial implant intended to replace the human urinary and excretory organs

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2255877B1 (en) 1973-12-28 1976-10-08 Rhone Poulenc Ind
US5514378A (en) * 1993-02-01 1996-05-07 Massachusetts Institute Of Technology Biocompatible polymer membranes and methods of preparation of three dimensional membrane structures
DE4324085A1 (en) 1993-07-17 1995-01-19 Basf Ag Process for the decomposition of organic halogen compounds in dust-containing exhaust gases
US5654273A (en) * 1994-09-22 1997-08-05 Children's Medical Center Corporation Synducin mediated modulation of tissue repair
US5586438A (en) * 1995-03-27 1996-12-24 Organ, Inc. Portable device for preserving organs by static storage or perfusion
CA2214407C (en) * 1995-04-07 2008-06-17 Purdue Research Foundation Tissue graft and method for urinary bladder reconstruction
US5755791A (en) * 1996-04-05 1998-05-26 Purdue Research Foundation Perforated submucosal tissue graft constructs
US6537567B1 (en) * 1997-07-03 2003-03-25 Massachusetts Institute Of Technology Tissue-engineered tubular construct having circumferentially oriented smooth muscle cells
DE19861492B4 (en) 1997-08-26 2015-04-23 Schaeffler Technologies Gmbh & Co. Kg Hydrodynamic torque converter
JP4057781B2 (en) * 1997-10-31 2008-03-05 チルドレンズ メディカル センター コーポレーション Bladder reconstruction
AU1588099A (en) * 1997-11-17 1999-06-07 Beth Israel Deaconess Medical Center Hybrid tissues for tissue engineering
JP4242078B2 (en) * 1999-03-18 2009-03-18 ヴァッセルマン、ヘルムート Artificial urination device
DE19912472B4 (en) 1999-03-18 2011-03-17 Wassermann, Helmut, Prof. Artificial urinary drainage system
US7131996B2 (en) 1999-03-18 2006-11-07 Helmut Wasserman Artificial urinary diversion device
US6432712B1 (en) * 1999-11-22 2002-08-13 Bioscience Consultants, Llc Transplantable recellularized and reendothelialized vascular tissue graft
US6428802B1 (en) * 1999-12-29 2002-08-06 Children's Medical Center Corp. Preparing artificial organs by forming polylayers of different cell populations on a substrate
EP1448247B1 (en) * 2001-11-16 2011-02-16 Children's Medical Center Corporation Creation of tissue engineered female reproductive organs
US20040029266A1 (en) * 2002-08-09 2004-02-12 Emilio Barbera-Guillem Cell and tissue culture device
WO2005089823A1 (en) * 2004-03-19 2005-09-29 Japan Science And Technology Agency Settling agent for hollow organ to be regenerated, hollow organ to be regenerated of settling type, method of constructing hollow organ to be regenerated of settling type and method of regenerating and settling hollow organ

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6296668B1 (en) * 1997-02-14 2001-10-02 Assistance Publique-Hopitaux De Paris Artificial implant intended to replace the human urinary and excretory organs

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
FALKE ET AL.: "Tissue Engineering of the Bladder", WORLD J. UROL., vol. 18, 2000, pages 36 - 43, XP009122733 *
KENEFICK ET AL.: "Injectable Silicon Biomaterial for Faecal Incontinence Due to Internal Anal Sphincter Dysfunction", GUT, vol. 51, 2002, pages 225 - 228, XP008130359 *
TUBARO A.: "The Artificial Bladder", EUR. UROL., vol. 35, 1999, pages 257 - 266, XP008130372 *

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CA2641733A1 (en) 2007-08-23
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US7918897B2 (en) 2011-04-05
CA2871840A1 (en) 2007-08-23

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