WO2007134140A3 - A fluid light guide system - Google Patents

A fluid light guide system Download PDF

Info

Publication number
WO2007134140A3
WO2007134140A3 PCT/US2007/068615 US2007068615W WO2007134140A3 WO 2007134140 A3 WO2007134140 A3 WO 2007134140A3 US 2007068615 W US2007068615 W US 2007068615W WO 2007134140 A3 WO2007134140 A3 WO 2007134140A3
Authority
WO
WIPO (PCT)
Prior art keywords
fluid light
light guide
fluid
flow channel
guide system
Prior art date
Application number
PCT/US2007/068615
Other languages
French (fr)
Other versions
WO2007134140A2 (en
Inventor
Barrett E Cole
Original Assignee
Honeywell Int Inc
Barrett E Cole
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Honeywell Int Inc, Barrett E Cole filed Critical Honeywell Int Inc
Publication of WO2007134140A2 publication Critical patent/WO2007134140A2/en
Publication of WO2007134140A3 publication Critical patent/WO2007134140A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/02—Optical fibres with cladding with or without a coating
    • G02B6/032—Optical fibres with cladding with or without a coating with non solid core or cladding
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure

Abstract

A system having a flow channel for conveying a sample and having fluid light guides for projecting light to the sample target area and collecting light from the sample target area. The system may have fluid light guides on or off the card containing the flow channel. Accurate alignment may be provided by the fluid light guides in lieu of requiring precise alignment for the light source and detectors. The flow channel may be a part of a cytometer system.
PCT/US2007/068615 2006-05-12 2007-05-10 A fluid light guide system WO2007134140A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/383,166 US7551278B2 (en) 2006-05-12 2006-05-12 Fluid light guide system
US11/383,166 2006-05-12

Publications (2)

Publication Number Publication Date
WO2007134140A2 WO2007134140A2 (en) 2007-11-22
WO2007134140A3 true WO2007134140A3 (en) 2008-03-13

Family

ID=38684798

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/068615 WO2007134140A2 (en) 2006-05-12 2007-05-10 A fluid light guide system

Country Status (2)

Country Link
US (1) US7551278B2 (en)
WO (1) WO2007134140A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9034277B2 (en) 2008-10-24 2015-05-19 Honeywell International Inc. Surface preparation for a microfluidic channel
US10036881B2 (en) 2014-05-23 2018-07-31 Pathonomic Digital microscope system for a mobile device
JP2019184337A (en) * 2018-04-05 2019-10-24 ソニー株式会社 Microchip, particulate measurement device, and particulate measurement method

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6438279B1 (en) * 1999-01-07 2002-08-20 Cornell Research Foundation, Inc. Unitary microcapiliary and waveguide structure and method of fabrication
GB2383127A (en) * 2001-12-12 2003-06-18 Proimmune Ltd Device and method for investigating analytes in liquid suspension or solution
US20030214057A1 (en) * 2002-05-15 2003-11-20 Zhili Huang Microstructure fabrication and microsystem integration
WO2005033654A2 (en) * 2003-08-28 2005-04-14 The Regents Of The University Of Michigan Micro flow cytometer with multiangular waveguide detectors having spectral capabilities

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
DE2433219A1 (en) * 1973-10-19 1976-01-22 Nath Guenther FLEXIBLE LIGHT GUIDE
DE2854684C2 (en) * 1978-12-18 1980-10-30 Original Hanau Heraeus Gmbh, 6450 Hanau Light guides, in particular for operating or examination lights
US4711126A (en) * 1985-03-13 1987-12-08 501 Nederlandse Centrale Organisatie Voor Toegepast-Enschappelijk Onderzoek Sensor for the measurement of the refractive index of a fluid and/or phase boundary between two fluids by means of visible or invisible light
DE3812203A1 (en) * 1988-04-13 1989-10-26 Fraunhofer Ges Forschung ARRANGEMENT FOR IN / OUT COUPLING LIGHT IN / OUT OF A LIGHT WAVE GUIDE
US5573531A (en) * 1994-06-20 1996-11-12 Gregory; Kenton W. Fluid core laser angioscope
US5608834A (en) * 1994-10-07 1997-03-04 United States Surgical Corporation Liquid Light guide
US5717807A (en) * 1995-07-14 1998-02-10 United States Surgical Corporation Liquid light guide with improved sealing characteristics
US5859946A (en) * 1997-06-27 1999-01-12 Southeastern Univ. Research Assn. Liquid-core light guide designed to withstand interior bubble formation from temperature-induced volumetric variations
US5836750A (en) * 1997-10-09 1998-11-17 Honeywell Inc. Electrostatically actuated mesopump having a plurality of elementary cells
EP1119786B1 (en) * 1998-08-12 2007-02-21 Rofin Australia PTY Ltd Fluid light guide
US6597438B1 (en) * 2000-08-02 2003-07-22 Honeywell International Inc. Portable flow cytometry
US6970245B2 (en) * 2000-08-02 2005-11-29 Honeywell International Inc. Optical alignment detection system

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6438279B1 (en) * 1999-01-07 2002-08-20 Cornell Research Foundation, Inc. Unitary microcapiliary and waveguide structure and method of fabrication
GB2383127A (en) * 2001-12-12 2003-06-18 Proimmune Ltd Device and method for investigating analytes in liquid suspension or solution
US20030214057A1 (en) * 2002-05-15 2003-11-20 Zhili Huang Microstructure fabrication and microsystem integration
WO2005033654A2 (en) * 2003-08-28 2005-04-14 The Regents Of The University Of Michigan Micro flow cytometer with multiangular waveguide detectors having spectral capabilities

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BROWN MATT ET AL: "Optical waveguides via viscosity-mismatched microfluidic flows", APPLIED PHYSICS LETTERS, AIP, AMERICAN INSTITUTE OF PHYSICS, MELVILLE, NY, US, vol. 88, no. 13, 30 March 2006 (2006-03-30), pages 134109 - 134109, XP012080898, ISSN: 0003-6951 *
KOU Q ET AL: "On-chip optical components and microfluidic systems", MICROELECTRONIC ENGINEERING, ELSEVIER PUBLISHERS BV., AMSTERDAM, NL, vol. 73-74, June 2004 (2004-06-01), pages 876 - 880, XP004510571, ISSN: 0167-9317 *
LEE G-B ET AL: "Micro flow cytometers with buried SU-8/SOG optical waveguides", SENSORS AND ACTUATORS A, ELSEVIER SEQUOIA S.A., LAUSANNE, CH, vol. 103, no. 1-2, 15 January 2003 (2003-01-15), pages 165 - 170, XP004400396, ISSN: 0924-4247 *
LIEN V ET AL: "Monolithically integrating photonic and microfluldic devices using a self-aligned process", LEOS 2003. 16TH. ANNUAL MEETING OF THE IEEE LASERS & ELECTRO-OPTICS SOCIETY. TUCSON, AZ, OCT. 27 - 28, 2003, ANNUAL MEETING OF THE IEEE LASERS AND ELECTRO-OPTICS SOCIETY, NEW YORK, NY : IEEE, US, vol. VOL. 1 OF 2, 26 October 2003 (2003-10-26), pages 525 - 526, XP010674886, ISBN: 0-7803-7888-1 *
VEZENOV DMITRI ET AL: "Integrated fluorescent light source for optofluidic applications", APPLIED PHYSICS LETTERS, AIP, AMERICAN INSTITUTE OF PHYSICS, MELVILLE, NY, US, vol. 86, no. 4, 18 January 2005 (2005-01-18), pages 41104 - 41104, XP012066159, ISSN: 0003-6951 *
WOLFE D B ET AL: "Dynamic control of liquid-core/liquid-cladding optical waveguides", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 101, no. 34, 24 August 2004 (2004-08-24), pages 12434 - 12438, XP002395276, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
WO2007134140A2 (en) 2007-11-22
US20070263216A1 (en) 2007-11-15
US7551278B2 (en) 2009-06-23

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